Clinical trials: Brain Activity
Brain Diseases
Physical Activity, Sleep and Brain Health Based on the Glymphatic System
This study is aiming to analyze the impact of physical activity on neurohydrodynamics and glymphatic activity on young adults. This study is designed as a multicenter descriptive observational study with information collection at…
- Trial name
- NCT06378515
- Testing
- Physical activity, postural changes and cognitive tasks
- Where
- Spain
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Brain Tumor Adult
Feasibility Assessment of Adapted Physical Activity in Patients Treated for a Brain Tumor
The goal of this clinical trial is to assess the feasibility of an adapted physical activity (APA) program in adult patients (≥18 years) with primary brain tumors, regardless of tumor type, grade, treatment stage, or the presence…
- Trial name
- APATC (NCT07570485)
- Testing
- adapted physical activity
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Center Eugene Marquis
Visual Impairment, Stroke
Re-Orchestration of Interregional Oscillatory Activity to Promote Visual Recovery
This project assesses the effect of bifocal cross-frequency transcranial alternating current stimulation (tACS) combined with visual training to improve visual recovery and orchestrated oscillatory activity in stroke patients…
- Conditions
- Visual Impairment, Stroke, Parkinson Disease
- Trial name
- R4V (NCT05220449)
- Testing
- Cross-frequency dual-site tACS
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Atrial Fibrillation
Explore the Efficacy and Safety of Once-daily Oral Rivaroxaban for the Prevention of Cardiovascular Events in Subjects With Nonvalvular Atrial Fibrillation Scheduled for Cardioversion
A study for patients with abnormal heart rhythm (atrial fibrillation) who need to undergo cardioversion (procedure to restore normal heart rhythm).
- Trial name
- X-VERT (NCT01674647)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Vitamin K antagonist (VKA)
- Where
- 178 sites in United States, Belgium and 15 more
- Volunteers
- 1,504 people
- Sponsor
- Bayer
Learning Disabilities, Cerebral Palsy
Efficacy of AAC for Functional Communication
There is a considerable number children who are unable to speak, and our currently not being provided with any AAC options in their therapeutic facilities.
- Conditions
- Learning Disabilities, Cerebral Palsy, Down Syndrome
- Trial name
- NCT04583332
- Testing
- Rhymes, Individual Items in Rhymes, Objects
- Where
- Pakistan
- Volunteers
- 12 people
- Sponsor
- Riphah International University
Alzheimer Disease
PET Study of Acetylcholine Esterase Activity in Alzheimer's Disease
The aim of this study is to understand regional variations in acetylcholine esterase activity in Alzheimer's disease. In this study the aim is to identify by PET the physiological values of the regional activity of acetylcholine…
- Trial name
- NCT06180252
- Testing
- PET with 11C MP4
- Volunteers
- 30 people
- Sponsor
- IRCCS San Raffaele
Old Age; Dementia, Old Age; Debility
Significant Activities in the Integrated Person-centered Care Model
The increasing life expectancy and global aging population necessitate changes in long-term gerontological services based on Person-Centred Care approaches.
- Trial name
- IO/20240924 (NCT06623864)
- Testing
- meaningful activities, other activities
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad de Burgos
Cerebrovascular Accident, Stroke
Reshaping Exercise Habits and Beliefs (REHAB)
Regular exercise has been demonstrated to improve muscle strength, balance, coordination as well as improve cardiovascular fitness levels and overall quality of life in stroke survivors.
- Trial name
- REHAB (NCT00431821)
- Testing
- Exercise, Stroke education
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- US Department of Veterans Affairs
Stroke
Comparative Effects of Motor Imagery and Mirror Therapy Versus Motor Relearning Program in Subacute Stroke Patients
Use of motor imagery, mirror therapy and motor relearning program in rehabilitation of people with stroke is on rise and these are unique and emerging techniques.
- Trial name
- NCT06308211
- Testing
- MOTOR IMAGERY+MIRROR THERAPY+ROUTINE PHYSICAL THERAPY, MOTOR RELEARNING PROGRAM+ROUTINE PHYSICAL THERAPY
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Stroke
Just In Time Intervention to Enhance Physical Activity Among Stroke Survivors
A 3-month single-arm pilot trial to evaluate the feasibility of an automated and individualized coping intervention among stroke survivors.
- Trial name
- NCT06693999
- Testing
- Google-Pixel Watch 3, Exercise prompts
- Sponsor
- Milton S. Hershey Medical Center
fMRI Research
Brain Activity During Bladder Filling: Pilot Study of an fMRI Protocol
Urinary incontinence is the most frequently observed lower urinary tract symptom (LUTS) in children with cerebral palsy (CP) (Samijn et al., 2016).
- Trial name
- NCT05255692
- Testing
- invasive urodynamic evaluation, functional magnetic resonance imaging during bladder filling
- Where
- Belgium
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment
Effects of Combined Aerobic and Cognitive Training in a Simultaneous or Sequential Paradigm on Cognition and Brain Functional Activity in Patients with AMCI
Mild Cognitive Impairment (MCI) is a condition in which patients show an objective evidence of impairment in one or more cognitive domains but a spared independence in daily functional abilities.
- Conditions
- Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment, Neurodegenerative Dementia, Neurodegenerative Disease
- Trial name
- NCT06755164
- Testing
- Simultaneous aerobic and cognitive training (SIM), Sequential aerobic and cognitive training (SEQ)
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Stroke
Exercise For Sub-acute Stroke Patients in Jamaica
Chronic hemiparetic stroke is associated changes in body composition, skeletal muscle and cardiometabolic health; specific changes include paretic limb muscular atrophy, increased intramuscular fat deposition, elevated prevalence…
- Trial name
- JAMMS (NCT01392391)
- Testing
- Task Oriented Exercise Training, Stroke Care "Get with the Guidelines"
- Where
- 2 sites in United States, Jamaica
- Volunteers
- 150 people
- Sponsor
- Baltimore VA Medical Center
Cognitive Dysfunction
Cognitive Leisure and Preclinical Alzheimer's Disease: Exploring Neural Mechanisms
The goal of this clinical trial is aims to: 1. Translate and culturally adapt the Cognitive Leisure Activity Scale (CLAS) into Chinese and Conduct reliability and validity tests for the Chinese version of CLAS. 2.
- Trial name
- NCT06215274
- Testing
- Relationship of the cognitive leisure activity levels, cognitive function, and MRI characteristics.
- Where
- China
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Yuanjiao Yan
Cognitive Change
Sharing History Through Active Reminiscence and Photo-imagery (SHARP) Pilot Program
SHARP is a neighborhood-based and technology-supported approach to brain health for older Black adults that integrates walking and image-prompted social reminiscence to maintain or improve brain health.
- Trial name
- SHARP (NCT05906654)
- Testing
- Sharing History through Active Reminiscence and Photo-imagery (SHARP)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Fetal Hypoxia
Intra-uterine Fetal Brain Activity Monitoring.
Fetal cardiac monitoring is used during labor. Fetal decelerations may imply fetal hypoxia and distress. Brain activity monitoring is not used to evaluate fetal distress during labor.
- Trial name
- NCT03930277
- Testing
- Electroencephalogram
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
Hemiplegic Cerebral Palsy, Motor Activity
Action Observation Based Rehabilitation of Children With Unilateral Cerebral Palsy
Recent evidence suggested that Action Observation Therapy (AOT), based on observation of actions followed by immediate reproduction, could be a useful rehabilitative strategy for promoting functional recovery of children affected…
- Trial name
- NCT04088994
- Testing
- AOT Pathological Model Experimental Group, AOT Healthy Model Control Group
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Parma
Motor Learning and Physiological Adaptation
Effects of Active Upper-Limb Exoskeleton Training in Simulated Hyper-Gravity on Fine Motor Performance, Brain-Muscle Connectivity, Cardiovascular System and Stress Responses in Real Hyper-Gravity
The aim of the study presented here is to assess the effects of exoskeleton training on performance in a real hypergravity situation.
- Trial name
- EGOS (NCT07278245)
- Testing
- Training with an exoskeleton
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre National d'Etudes Spatiales
Frozen Shoulder
Effects of App-assisted Home Exercise Program in Patients With Frozen Shoulder
Abstract Introduction Frozen shoulder is a common musculoskeletal disorder with reported lifetime prevalence to be 2%~5% in the general population.
- Trial name
- NCT05980572
- Testing
- Glenohumeral joint and subacromial space triamcinolone injections, App-assisted exercise, Nonsteroidal anti-inflammatory drugs (aceclofenac)
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- Chang Gung Memorial Hospital
Bipolar Disorder Depression
Broadband Near Infrared Spectroscopy to Understand the Role of Brain Cytochrome C Oxidase in Bipolar Disorder
People with a diagnosis of bipolar disorder who are depressed will have a light-based imaging of the brain (Near Infrared Spectroscopy) before and after they have treatment for their depression with a standard, approved…
- Trial name
- NCT07806227
- Testing
- Lurasidone (Latuda)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Martin Lan
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