Clinical trials: Brain Activity
Parkinson Disease
Pre-Active PD: Looking At Physical Activity Behavior Change in Parkinson's Disease
Pre-Active PD is a randomized controlled feasibility study to evaluate the implementation of a telehealth-delivered physical activity behavior change intervention for people with early-mid stage Parkinson's disease.
- Trial name
- NCT05308238
- Testing
- Occupational therapy intervention group, Disease management education group
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- San Jose State University
Stroke, Upper Extremity Paresis
Effects of Robot-Assisted Rehabilitation on Upper Extremity Functions in Chronic Stroke
The most common problem caused by stroke is motor activity limitation that reduces muscle movement and mobility. But stroke can also lead to sensory and cognitive impairment.
- Trial name
- NCT06306313
- Testing
- ReoGo, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Nicotine Dependence
Brain Activity and Smoking Cessation
In the current study, the investigators propose to test: (1) whether brain activation and connectivity in a resting state, assessed by ASL perfusion MRI, BOLD fMRI, and diffusion tensor imaging (DTI) predicts smoking relapse, and…
- Trial name
- NCT01186055
- Testing
- Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Traumatic Brain Injury
MENTOR Wellness Program
This randomized trial aims to determine the effectiveness a virtual wellness intervention program in individuals with traumatic brain injury (TBI).
- Trial name
- NCT06148324
- Testing
- MENTOR Program
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- NYU Langone Health
Mild Cognitive Impairment, Mild Dementia
Shanghai Non-pharmacological Intervention for Mild Cognitive Impairment and Mild Alzheimer's Disease
This study is a multicentre, randomized, double-blind, controlled trial that aims to investigate the efficacy of multi-domain life-style intervention including low inflammatory-index diet, exercise, and cognitive training in…
- Trial name
- SIM-2 (NCT05887674)
- Testing
- Diet intervention, Exercise, Cognitive training
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Ruijin Hospital
Memory Loss (Excluding Dementia), Lifestyle (Sedentary Behavior and Physical Activity)
Pilot Study of a Brain Health Program in Senior Centers
The investigators will evaluate a brain health programs in older adults with subjective cognitive decline. The primary aim of the study is to determine the credibility, expectancy, feasibility, acceptability, appropriateness…
- Conditions
- Memory Loss (Excluding Dementia), Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Risk Reduction, Healthy Lifestyle Behaviors
- Trial name
- NCT07424443
- Testing
- My Healthy Brain
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Parkinson Disease
Effects of Home-based Exercise in Parkinson's Disease
Home-based exercise program focusing on axial rigidity could be used as an adjunct rehabilitation program to improve rotational movement, gait and functional movement associated with axial rigidity in individuals with PD.
- Trial name
- NCT04810897
- Testing
- Exercise
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Parkinson Disease (PD)
Passive Versus Active Music Therapy Parkinson's Disease
The purpose of this pilot study is to identify the effects of active versus passive music therapy on functional ability and psychophysiological responses to goal-directed exercise in people with Parkinson's disease.
- Trial name
- NCT07661524
- Testing
- Passive music therapy, Active music therapy
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- University of Alabama at Birmingham
Brain Health, Cognition
Exercise Effects on Cognition in School-Aged Children
Recent trends have identified decreasing levels of physical activity, fitness, and health in preadolescent children. Examining factors, such as physical activity behavior and aerobic fitness that positively influence cognitive…
- Conditions
- Brain Health, Cognition, Scholastic Achievement
- Trial name
- FITKids (NCT01334359)
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Cardiovascular Diseases (CVD), Metabolic Syndrome
Ambient Air and Noise Effect on Cardiovascular Health Risk and Lifestyle Intervention to Attenuate It (METSGREEN)
This study, combining both an observational study and an interventional clinical trial, aims to assess how exposure to ultrafine particulate matter (PM0.1) and noise pollution affects the risk of cardiovascular diseases and…
- Conditions
- Cardiovascular Diseases (CVD), Metabolic Syndrome, Air Pollution Exposure, Environmental Exposure
- Trial name
- METSGREEN (NCT07111208)
- Testing
- Green Space Activity Group - Daily Physical Activity, Mediterranean Diet Group - Dietary Intervention
- Where
- 2 sites in Lithuania
- Volunteers
- 180 people
- Sponsor
- Regina Grazuleviciene
Schizophrenia
Brain Image Markers Associated With Cognitive Training and Aerobic Exercise in Schizophrenia
This study evaluates the brain correlates of Cognitive Training and Aerobic Exercise in schizophrenia. A third of participants will receive Cognitive Training plus Standard Care for schizophrenia.
- Trial name
- CORTEX-SP (NCT03509597)
- Testing
- Aerobic Exercise, Cognitive Training, Treatment as usual
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Red Salud Mental Araba
Cerebral Palsy
Diet and Activity in Cerebral Palsy
This study aims to fill a gap in the literature, identify relevant clinical measures, and provide insight into the independent modifiable risk factors of obesity in the CP population with the long-term goal of improving…
- Trial name
- NCT02175108
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Shirley Ryan AbilityLab
Mental Fatigue, Recovery
Effects of Different Nap Durations on Volleyball Performance and EEG Activity Following Mental Fatigue
Mental fatigue is known to impair cognitive and physical performance in athletes, but the effectiveness of different nap durations in counteracting these effects remains unclear.
- Conditions
- Mental Fatigue, Recovery, Volleyball, Sport Performance
- Trial name
- MFNAP (NCT07700576)
- Testing
- Mental Fatigue Induction, Control Condition, Daytime Nap 20 Minutes
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Inonu University
Dementia
Decreasing Agitation in Patients With Dementia Through the Use of Weighted Blankets
The purpose of this research study is to determine whether the use of weighted blankets help reduce behavioral and psychological symptoms, including agitation in people with dementia.
- Trial name
- NCT03643991
- Testing
- Weighted Blanket
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Tension-Type Headache
Exercise Treatment in Tension Type Headache
Tension-type headache (TTH) is a common type of headache. Its incidence in women has been reported as 18%. It is thought to be associated with stress, contractions in peripheral muscles, and changes in pain transmission and…
- Trial name
- NCT05431335
- Testing
- Structured exercise program, Aerobic exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Munzur University
Idiopathic Parkinson's Disease
The Effect of Pramipexole on Metabolic Network Activity Compared With Levodopa in Early Parkinson's Disease
Levodopa and non-ergot dopaminergic agonists such as pramipexole are both recommended as the first-line symptomatic treatment for early untreated Parkinson's disease (PD), previous clinical trial indicated that initial…
- Trial name
- NCT01470859
- Testing
- pramipexole, Sinemet CR
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huashan Hospital
Chronic Brain Injury
SPIRIT Club Chronic Brain Injury Exercise Platform
Many physical fitness centers and online exercise programs are not designed to support people with intellectual and developmental disabilities.
- Trial name
- SPIRITClubCBI (NCT07169370)
- Testing
- SPIRIT Club CBI Pathway
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ohio State University
Multiple Sclerosis
Acute Effects of Walking Exercise on Brain Functioning in Multiple Sclerosis
The project will involve a within-subjects, repeated-measures research design. Participants will initially be screened for relevant inclusion/exclusion criteria for maximizing safety of participating in an exercise study.
- Trial name
- PRIMERS (NCT06233370)
- Testing
- Moderate intensity walking exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kessler Foundation
Stroke, Stress, Psychological
Stroke Rehabilitation Utilizing Therapeutical Methods Designed for Nature Environments
Outpatient participants with a recent stroke diagnoses receive complimentary rehabilitation. The nature interventions include ergo- and physiotherapeutic and neurocognitive tasks with the support of an psychotherapeutic frame…
- Conditions
- Stroke, Stress, Psychological, Post Traumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT06633146
- Testing
- Therapies in nature
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Stroke, Hemiplegia
Cardiovascular Function in Sub Maximal Exercise and Performance in Three Daily Activity Tests After Stroke
The purpose of this study is to explore the relationship between cardiovascular function of persons with post stroke conditions and their performance in three field tests.
- Trial name
- NCT01396746
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hillel Yaffe Medical Center
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