Clinical trials: Brain Damage, Chronic
Cerebral Palsy, Hip Dislocation
GUIDed Growth of the Proximal Femur to Prevent Further Hip MigrAtion in CErebral Palsy Patients
In recent literature, the potential of guided growth of the proximal femur to modify hip growth in patients with cerebral palsy has been shown.
- Trial name
- GUIDANCE (NCT06118736)
- Testing
- Temporary Medial Hemi-epiphysiodesis of the proximal femur
- Where
- 5 sites in Netherlands
- Volunteers
- 84 people
- Sponsor
- Erasmus Medical Center
Cerebral Palsy, Spasticity, Muscle
Shock Wave Therapy for Management of Spasticity in Patients With Cerebral Palsy
Spasticity is the most common motor disorder in cerebral palsy (CP). The objectives of his therapeutic approach include; reducing pain, ease of use of orthopedic aids, improving posture, minimizing contractures and deformity, and…
- Conditions
- Cerebral Palsy, Spasticity, Muscle, Extracorporeal Shock Wave Therapy
- Trial name
- NCT05702606
- Testing
- Radial extracorporeal shock wave therapy (rESWT)
- Where
- Spain
- Volunteers
- 73 people
- Sponsor
- Fundacio Aspace Catalunya
Cerebral Palsy, Hemiplegia
Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy
A randomized control trial of bimanual training. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement therapy in children with…
- Conditions
- Cerebral Palsy, Hemiplegia, Children, Pediatric
- Trial name
- NCT00305006
- Testing
- Constraint-Induced Movement Therapy (CIMT), Hand-Arm Bimanual Intensive Therapy (HABIT)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Teachers College, Columbia University
Disorder of Consciousness, Minimally Conscious State
Two Intensities of Transcranial Direct Current Stimulation to Improve Consciousness in Severely Brain Injured Patients
Limited treatments are available to improve consciousness in severely brain injured patients. Transcranial Direct Current stimulation (tDCS) is one of the few therapeutics that showed evidence of efficacy to increase level of…
- Conditions
- Disorder of Consciousness, Minimally Conscious State, Vegetative State, Cognitive Impairment
- Trial name
- STIMCOM (NCT03007784)
- Testing
- transcranial direct current stimulation (tDCS) / Comparison of current intensities
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Spastic Diplegia Cerebral Palsy
Post Facilitation Stretch, Post Isometric Relaxation and Myofascial Release in Spastic Cerebral Palsy.
The purpose of the study is to compare the effect of Post Facilitation Stretch, Post Isometric Relaxation and Myofascial Release on Lower Limb Spasticity in Spastic Cerebral Palsy.
- Trial name
- NCT06686719
- Testing
- Post Facilitation, Post Isometric Relaxation, Myofascial Release
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation
Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI
Provision of interventions that address cognitive and emotional problems faced by Veterans with history of TBI pursuing community reintegration is an important concern for VA.
- Conditions
- Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation, Veteran
- Trial name
- GOALS TH (NCT07190365)
- Testing
- GOALS TH, EDU TH
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
CP (Cerebral Palsy)
Examination of the Effects of Video-Based Games on Balance, Trunk Proprioception, Motivation and Quality of Life in Individuals With Cerebral Palsy
In the study we planned, 42 individuals diagnosed with cerebral palsy will be divided into 2 groups according to age groups. Individuals aged 4-11 will be included in the child group, and individuals aged 12-18 will be included…
- Trial name
- NCT05667792
- Testing
- Microsoft Kinect 360, Pediatric Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Mustafa Kemal University
Cerebral Palsy (CP)
Evaluating the Bambini Teens Exoskeleton for Pediatric Cerebral Palsy
The goal of this clinical trial is to evaluate the safety and effectiveness of the Bambini Teens exoskeleton as a gait training tool in children aged 5 to 14 years diagnosed with cerebral palsy (CP).
- Trial name
- NCT07146932
- Testing
- Pediatric Lower Limb Exoskeleton (Bambini Teens)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- COSMO ROBOTICS CO., Ltd
Cerebral Palsy, Periventricular Leukomalacia
A Study to Investigate the Safety and Efficacy of UC-MSCs in Pediatric Patients With Cerebral Palsy
UDI-001 is administered to pediatric patients with cerebral palsy attributed to periventricular leukomalacia (PVL) multiple times to investigate its safety and efficacy.
- Trial name
- NCT04873752
- Testing
- UDI-001
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Rohto Pharmaceutical Co., Ltd.
Traumatic Brain Injury
Executive Function Training Intervention for Chronic Traumatic Brain Injury
Traumatic Brain Injury (TBI) is a prevalent disorder developed by military personnel. While some individuals recover function within months after injury, others continue to suffer from cognitive problems months to years later and…
- Trial name
- NCT03704116
- Testing
- Expedition
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The University of Texas at Dallas
Rehabilitation, Cerebral Palsy (CP)
Effects of Motor Imagery Training After Muscle Lengthening Surgery in Children With Cerebral Palsy
In children with cerebral palsy (CP), spasticity occurs in the muscles due to upper motor neuron lesions. The muscle groups that are mostly spastic in the lower extremity are; the hip adductor and flexors, hamstrings, and ankle…
- Conditions
- Rehabilitation, Cerebral Palsy (CP), Exercise, Tenotomy
- Trial name
- NCT06838858
- Testing
- Motor Imagery Training, Conventional Post-operative Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Saglik Bilimleri Universitesi
Hemiplegic Stroke, Hemiplegic Cerebral Palsy
Evaluating Human-Machine Interfaces in a Robotic Thumb Orthosis
We plan to investigate whether the Isolated Orthosis for Thumb Actuation (IOTA) can effectively facilitate the ability of participants to perform a specific set of clinically relevant tasks conducted in a clinic setting.
- Trial name
- IOTA (NCT01973426)
- Testing
- Isolated Orthosis for Thumb Actuation (IOTA)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wyss Institute at Harvard University
Disorder of Consciousness, Minimally Conscious State
Temporal Interference Stimulation for Disorders of Consciousness
This study aims to investigate whether a new non-invasive brain stimulation technique, called temporal interference stimulation, can influence brain activity and potentially improve signs of consciousness in patients with severe…
- Conditions
- Disorder of Consciousness, Minimally Conscious State, Vegetative State, Unresponsive Wakefulness Syndrome
- Trial name
- NCT07874178
- Testing
- Temporal Interference
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Spastic Cerebral Palsy, Motor Activity
Investigation of the Relationship Between Lower and Upper Extremity Selective Motor Control and Sensory Functions in Children With Spastic Cerebral Palsy
Although spasticity, contractures and muscle weakness in children with CP are disorders that can be observed more easily and are more focused and given more importance in evaluation and treatment approaches; Inadequate or loss of…
- Conditions
- Spastic Cerebral Palsy, Motor Activity, Lower Extremity Problem, Upper Extremity Problem
- Trial name
- NCT05696535
- Volunteers
- 100 people
- Sponsor
- Mustafa Kemal University
Cerebral Palsy
Multiple Transplantation of Bone Marrow Derived CD133 Cell in Cerebral Palsy
Cerebral palsy (CP) is condition, sometimes thought of as a group of disorders that can involve brain and nervous system functions such as movement, learning, hearing, seeing, and thinking.Cerebral palsy is caused by injuries or…
- Trial name
- NCT01763255
- Testing
- stem cell intrathecal injection
- Where
- Iran
- Volunteers
- 8 people
- Sponsor
- Royan Institute
Cerebral Palsy, Perinatal Stroke
Home-based Early Intensive Hemiparesis Therapy: Engaging Nurture
The purpose of the study is to assess implementation and effectiveness of a caregiver-delivered rehabilitation intervention for infants and toddlers with cerebral palsy.
- Trial name
- HEIGHTEN (NCT05346887)
- Testing
- Home-based Therapy
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Neuromotor Impairments, Cerebral Palsy
The FBRI VTC Neuromotor Research Clinic
The FBRI VTC Neuromotor Research Clinic was established and opened in May of 2013 to provide intensive therapeutic services to individuals with motor impairment secondary to neuromotor disorders. It is direct by Dr.
- Conditions
- Neuromotor Impairments, Cerebral Palsy, Microcephaly, Autism
- Trial name
- NCT03325946
- Testing
- ACQUIRE Therapy
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Virginia Polytechnic Institute and State University
Cerebral Palsy, Mobile Phone Use
Using Augmented Reality to Promote Physical Activity in Children With Cerebral Palsy
Children with cerebral palsy (CP), Gross Motor Functional Classification Scale (GMFCS) I-II will be recruited to participate in a home based physical activity intervention for 4 weeks.
- Conditions
- Cerebral Palsy, Mobile Phone Use, Pediatric ALL, Physical Disability
- Trial name
- NCT06096272
- Testing
- Augment Reality Exergames
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital Los Angeles
Cerebral Palsy
Effects of Pediatric Endurance and Limb Strengthening (PEDALS) Program VS Task-Oriented Training (TOT) Improving Gross Motor Function in Children With Cerebral Palsy
To compare the Effects of Pediatric endurance and limb strengthening (PEDALS) program VS Task-oriented Training (TOT) improving gross motor function among children with Cerebral Palsy.
- Trial name
- PEDALS (NCT06479395)
- Testing
- Pediatric Endurance and Limb Strengthening (PEDALS) program, Task-Oriented Training (TOT)
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Shalamar Institute of Health Sciences
Cerebral Palsy (CP)
TENS With Proprioceptive-Visual Training on Gait Parameters in CP
This study aimed to evaluate the effect of TENS with proprioceptive - visual training on gait parameters in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07338994
- Testing
- TENS, 1. Tekscan Walkway system
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University