Clinical trials: Brain Damage, Chronic
Cerebral Palsy, Bilateral Cerebral Palsy
Stepping to Understand Lower Limb Impairments in Bilateral Cerebral Palsy
The purpose of this study is to investigate lower limb impairments in children with bilateral cerebral palsy during stepping tasks.
- Conditions
- Cerebral Palsy, Bilateral Cerebral Palsy, Diplegic Cerebral Palsy
- Trial name
- NCT04957277
- Testing
- load modulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cerebral Palsy
Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities
This study is investigating the potential effects of a high-intensity home-exercise program among children with cerebral palsy. The program includes rhythmic movements to music that are adapted for wheelchair uses and…
- Trial name
- NCT05619211
- Testing
- Sprint-Intensity Interval Training with Telecoaching
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
TBI Traumatic Brain Injury
ESWT as a Treatment for Chronic NHO in TBI Patients
Effect of Extracorporeal Shock Wave Therapy on Chronic Neurogenic Heterotopic Ossification in Traumatic Brain Injured (TBI) patients Chronic Neurogenic Heterotopic Ossification (NHO) - Heterotopic ossification is a well known…
- Trial name
- NCT02331628
- Testing
- ESWT - Extracorporeal Shockwave Therapy
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Loewenstein Hospital
Cerebral Palsy, Spasticity, Muscle
Can Transcutaneous Electrical Stimulation Garment Improve Gait in Children With Cerebral Palsy?
Living with cerebral palsy is challenging for the child as well as the family charged with their care and support needs. Many families seek effective and sustainable interventions to improve gait of their children with cerebral…
- Trial name
- NCT04715334
- Testing
- Mollii suit
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- KK Women's and Children's Hospital
Gait Impairment, Cerebral Palsy (CP)
Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Kids device in pediatric patients with neurological gait disorders or muscular weakness during a 10-session gait training program…
- Conditions
- Gait Impairment, Cerebral Palsy (CP), Neuromuscular Diseases (NMD), Spinal Cord Injuries (SCI)
- Trial name
- NCT07745712
- Testing
- ABLE Kids
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- ABLE Human Motion S.L.
Cerebral Palsy
Hydrotherapy CP and Lying Down to Sitting Position
The purpose of this study is to investigate the effect of a very specific hydrotherapy programm on the movement from lying down to sitting position for children with CP
- Trial name
- NCT05091892
- Testing
- Hydrotherapy programm
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Thessaly
Cerebral Palsy
The Effects Of Upper Extremity Robotic Rehabilitation On Upper Extremity Functions And Gait Parameters
Cerebral Palsy is defined as the cause of movement and posture disorders and activity limitation that develops in the fetal or infant brain that has not yet completed its development.
- Trial name
- NCT05136612
- Testing
- conventional physiothrapy, robotic rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gazi University
Cerebral Palsy, Autism
Rehabilitation of Children With Multiple Disabilities
The objective of the study is to compare the usual care and treatment of children and youth (0-19 years) with multiple developmental delays and disabilities and their families in Simcoe York with a co-ordinated, navigated…
- Conditions
- Cerebral Palsy, Autism, Down's Syndrome, Brain Injury
- Trial name
- NCT01379443
- Testing
- CTN model of care for children and their families
- Where
- Canada
- Volunteers
- 445 people
- Sponsor
- Children's Treatment Network
Cerebral Palsy, Spina Bifida
Evaluation of the Transitional and Lifelong Care Program
The population cared for in the Transitional and Lifelong Care (TLC) clinic is youth and adults with childhood-onset disability, of which the large majority are adults with brain-based, neurodevelopmental conditions such as…
- Conditions
- Cerebral Palsy, Spina Bifida, Developmental Disability
- Trial name
- NCT05849285
- Testing
- TLC Clinic
- Where
- Canada
- Volunteers
- 410 people
- Sponsor
- Western University, Canada
Spastic Cerebral Palsy
Evaluation of Multifocal Transcutaneous Electrical Stimulation for Self-treatment Among Children With Cerebral Palsy
The main purpose with this study is to investigate the effectiveness of a garment with integrated electrodes for multifocal transcutaneous electrical stimulation intended for treatment of spasticity in children with cerebral…
- Trial name
- NCT04078321
- Testing
- Mollii ®
- Where
- Sweden
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sormland County Council, Sweden
Cerebral Palsy
Stem Cells in Umbilical Blood Infusion for CP
This study will investigate the safety of single dose intravenous infusion of cord blood cells which were cryopreserved after the birth of a brother or sister to a child with cerebral palsy.
- Trial name
- SCUBI-CP (NCT03087110)
- Testing
- Matched sibling donor cord blood cell infusion
- Where
- 2 sites in Australia
- Volunteers
- 12 people
- Sponsor
- Murdoch Childrens Research Institute
Rehabilitation, Cerebral Palsy (CP)
Effects of Motor Imagery Training After Muscle Lengthening Surgery in Children With Cerebral Palsy
In children with cerebral palsy (CP), spasticity occurs in the muscles due to upper motor neuron lesions. The muscle groups that are mostly spastic in the lower extremity are; the hip adductor and flexors, hamstrings, and ankle…
- Conditions
- Rehabilitation, Cerebral Palsy (CP), Exercise, Tenotomy
- Trial name
- NCT06838858
- Testing
- Motor Imagery Training, Conventional Post-operative Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Saglik Bilimleri Universitesi
Cerebral Palsy, Spastic, Balance; Distorted
Evaluation of Pediatric Balance Scale and Quantitative Balance Parameters in Patients With Cerebral Palsy
This study aims to evaluate Pediatric Balance Scale and quantitative balance and gait parameters assessed by Balance Master force plate in Cerebral Palsy (CP) patients who are ambulatory without an assistive device in daily life.
- Trial name
- NCT03417726
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Marmara University
Chronic and Severe Post-coma Disorders of Consciousness (Permanent Vegetative State, Minimally Conscious State)
Study of Conscious Behavior Under Low-frequency Deep Brain Stimulation in Chronic and Severe Post-coma Disorders of Consciousness
Chronic post-coma consciousness impairment is a severe handicap. Preliminary studies suggest that deep brain stimulation of the thalamic-tegmental reticular system could improve consciousness disorders, and facilitate the…
- Trial name
- Post-coma DBS (NCT01718249)
- Testing
- Implantable neurostimulation system
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain, Cerebral Palsy, Spastic
Botulinum Toxin-A as a Treatment for Chronic Muscle-Related Pain in Adults With Spastic Cerebral Palsy: a Randomized Controlled Trial
The purpose of this double-blinded, placebo-controlled study is to test if treatment with Botulinum toxin-A is effective in reducing chronic muscle-related pain in adults with spastic cerebral palsy.
- Trial name
- BATCP (NCT02434549)
- Testing
- Dysport®, Normal saline
- Where
- 2 sites in Sweden
- Volunteers
- 16 people
- Sponsor
- Kristina Tedroff
Cerebral Palsy
A Trial Comparing Two Methods of CIMT in the Hemiplegic Child
Cerebral palsy remains a major cause of lifelong disability affecting approximately 2 per 1,000 children. Of those about 30% have hemiplegic cerebral palsy (HPC),a unilateral impairment, which can often lead to major difficulties…
- Trial name
- HCPCIMT (NCT01770678)
- Testing
- Constraint Induced Movement Therapy
- Volunteers
- 62 people
- Sponsor
- University of Birmingham
Hip Dysplasia, Cerebral Palsy
A Randomized Control Trial of Hip Dislocation Techniques for Pediatric Patients With Cerebral Palsy
This randomized controlled trial will compare proximal femoral resection-interposition arthroplasty to proximal femoral resection with subtrochanteric valgus osteotomy for the treatment of painful irreducible hip dislocation in…
- Trial name
- NCT02259140
- Testing
- Proximal Femoral Resection Arthroplasty, Subtrochanteric Valgus Osteotomy
- Where
- 7 sites in United States, Canada
- Sponsor
- Hospital for Special Surgery, New York
Cerebral Palsy
Effects of Virtual Reality on Cerebral Palsy
Virtual reality (VR), is one of the most popular approaches to Cerebral Palsy (CP) rehabilitation and has been used in rehabilitation field for 30 years.
- Trial name
- NCT04768374
- Testing
- Virtual Reality with Kinect, Conventional Occupational Therapy (COT)
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people
- Sponsor
- Hacettepe University
Mild Traumatic Brain Injury, Chronic Pain
Neuromodulation and Yoga for Mild Traumatic Brain Injury and Chronic Pain
The objectives of this VA SPiRE application are to develop a combined neuromodulation and yoga (iTBS+yoga) intervention for Veterans with mild traumatic brain injury (mTBI) and chronic pain, assess the intervention's feasibility…
- Trial name
- NCT04517604
- Testing
- Magventure MagProx100 with MagOption
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Chronic Disease, Neoplasm Metastasis
Facilitating Communication Study
This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their…
- Conditions
- Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive
- Trial name
- FCS2 (NCT03721952)
- Testing
- Facilitator-Based Intervention
- Where
- 3 sites in United States
- Volunteers
- 977 people
- Sponsor
- University of Washington