Clinical trials: Brain Disorders
Neuropathy, Stroke
Effect of Spasticity on Tibial Nerve Entrapment
Stroke is the most common cause of mortality and is one of the most common causes of morbidity in the world. Polyneuropathies and entrapment neuropathies are known as the complications of stroke
- Trial name
- NCT06092190
- Testing
- EMG
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- October 6 University
Amblyopia
Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision Screening
Amblyopia, characterized by reduced visual acuity, develops in childhood due to insufficient sensory stimulation of the affected eye.
- Trial name
- FALSSE (NCT07112560)
- Testing
- Standard screening procedure for amblyopia, New amblyopia screening method using a virtual reality headset.
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Anesthesia, Neuroinflammation
Neuroinflammatory Biomarkers After General Anesthesia: A Comparison Study
This prospective, observational study investigates the impact of repeated general anesthesia exposure on neuroinflammatory biomarkers and neurotrophic factors.
- Conditions
- Anesthesia, Neuroinflammation, Cognitive Disorders
- Trial name
- NCT07388160
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
PARKINSON DISEASE (Disorder)
Open Label Single Arm Prebiotic Pilot Trial SR001
The goal of this pilot clinical study is to evaluate the effect of a prebiotic fiber blend in individuals diagnosed with Parkinson's Disease. The main objectives of this pilot study are: 1.
- Trial name
- NCT07127120
- Testing
- Prebiotic fiber blend
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sorridi Therapeutics
Neuro-Degenerative Disease
Synaptic Density, Tau and Multiparametric PET-MR in Brain Trauma, Stroke and Mild Cognitive or Behavioral Impairment.
Alzheimer's disease, stroke and TBI are frequently observed brain disorders, causing significant morbidity. For none of these disorders, there are in vivo diagnostic biomarkers available that allow determination of disease…
- Trial name
- NCT03514524
- Testing
- PET-MR imaging
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Dementia
The Genetic Characterization of Dementia
Background: Researchers are interested in learning more about dementia and its causes. They want to look at the genetic basis of dementia.
- Trial name
- NCT01867359
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Infant Development, Perinatal Stroke
Behavioral Assessment Method Index
The overall goal of this study is to develop and improve assessment methods for children with and without perinatal arterial ischemic stroke (PAS)/hemiparetic cerebral palsy (HCP).
- Conditions
- Infant Development, Perinatal Stroke, Hemiparesis, Cerebral Palsy
- Trial name
- BAM (NCT07291479)
- Testing
- Non interventional study
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Urea Cycle Disorders, Inborn, Inborn Errors of Metabolism
Increasing Ureagenesis in Inborn Errors of Metabolism With N-Carbamylglutamate
Hyperammonemia, which can cause brain damage, occurs in many different kinds of inborn errors of metabolism. The investigators propose to determine if short-term (3 day) treatment with N-carbamylglutamate can diminish…
- Conditions
- Urea Cycle Disorders, Inborn, Inborn Errors of Metabolism, Propionic Acidemia, Methylmalonic Acidemia
- Trial name
- NCT01341379
- Testing
- N-carbamylglutamate
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Malaria, Dengue
Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR
Rural communities involved in agriculture are often at highest risk of insect-borne diseases in Southeast (SE) Asia. Skin-applied insect repellents may prove a useful means of reducing mosquito-borne diseases for those people…
- Conditions
- Malaria, Dengue, Japanese Encephalitis
- Trial name
- NCT00938379
- Testing
- 20% deet insect repellent
- Where
- Laos
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Cerebral Palsy
Development of Kinect-assisted Home-based Bilateral Arm Training Program for Cerebral Palsy
The purpose of the present study is to develop a long term cost-effectiveness (efficient protocol, playful context, and practical strategy) training program for school-age children with Cerebral Palsy.
- Trial name
- NCT02801279
- Testing
- Conventional bilateral arm training, Kinect-based bilateral arm training
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dementia, Alzheimer Disease
The Brain Health Study: A Pragmatic, Patient-Centered Trial
The eRADAR Brain Health Study is an embedded, pragmatic clinical trial to determine whether targeted screening for dementia using the eRADAR algorithm increases dementia detection within primary care compared to usual care.
- Trial name
- eRADAR (NCT05905796)
- Testing
- Brain Health Assessment
- Where
- 3 sites in United States
- Volunteers
- 1,261 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cerebral Palsy, Prematurity
Study of Generalized Movements for Early Prediction of Cerebral Palsy
The purpose of this study is to assess the predictive value of generalized movements in preterm and term infants who are at risk for development of cerebral palsy.
- Trial name
- NCT00749008
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Charles R. Neal,
Stroke
Stroke COunseling for Risk REduction
The purpose of this study is to test the efficacy of the Stroke Counseling for Risk Reduction (SCORRE) intervention in increasing accuracy of perceived stroke risk and promoting lifestyle behavior change to reduce stroke risk in…
- Trial name
- SCORRE (NCT03076125)
- Testing
- SCORRE, Attention-Control Activity
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Cerebral Palsy
The Effect of Exercise Training on Musculoskeletal Health in Individuals With Cerebral Palsy
Cerebral palsy (CP) is a neurodevelopmental disorder and is the most common childhood disability. CP is characterized by abnormal development, impaired motor function, and muscular and skeletal abnormalities.
- Trial name
- NCT05070117
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- San Jose State University
Alzheimer Disease, Late Onset
Does BCG Vaccination Reduce Biomarkers of Alzheimer's Disease?
The goal of this clinical trial is to test whether vaccination with the BCG vaccine may improve the blood level of a biomarker of Alzheimer's disease (AD) in participants who are cognitively- and functionally- intact elderly…
- Trial name
- BCG-AD (NCT06078891)
- Testing
- BCG vaccine
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tamir Ben-Hur
Sepsis, Septic Shock
Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Background: Central Venous catheter insertion technique and indwelling time are major risk factors for CVC colonisation. Colonisation occurs through microbial migration and biofilm formation along the catheter insertion tract.
- Conditions
- Sepsis, Septic Shock, Post-cardiac Surgery, Post-Cardiorespiratory Arrest Coma
- Trial name
- NCT03270774
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makerere University
Hydrocephalus
Formative Usability Assessment of Wireless Thermal Anisotropy Devices
Measurements of shunt flow will be performed non-invasively. This study will generate usability data via observed tasks and comprehension questions to enable future device design improvements.
- Trial name
- NCT06040697
- Testing
- Thermal Anisotropy
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Rhaeos, Inc.
Menopause, Migraine
The Functional Magnetic Resonance Imaging Study on the Processing of Acute Pain and Cognition Among Perimenopause Women
There lacks effective early screen system for the migraine-susceptible women during the peri-menopause period. The processing of acute pain and cognition as well as the underling functional magnetic resonance imaging (fMRI)…
- Trial name
- NCT02820974
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Parkinson Disease
Study of Dysarthria, and the Appearance of Non-dopaminergic Signs in Idiopathic PARKinson's Disease
Pilot study: Longitudinal follow up of the PRODY-GI cohort for parkinson's disease (PD) Observational study of upper and lower axial symptoms' occurence in 30 PD patients in on and off drug conditions, 30 aged matched control…
- Trial name
- Prodygi-II (NCT03517059)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Alzheimer's Disease, Healthy Controls
Development of Eye-movement Based Biomarkers in Alzheimer's Disease
This study aims to develop and validate a sensitive and non-invasive eye-tracking software application. This study will obtain participant responses to brief cognitive tests designed to evaluate several key functions known to be…
- Trial name
- NCT05176704
- Testing
- Eye-Tracking
- Where
- 5 sites in Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- McGill University
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