Clinical trials: Brain Function, open to volunteers
Quality of Life (QOL), Anxiety
Testing the Efficacy of the "Syd" App on Improving Quality of Life and Mental Health Among University Students in the Kingdom of Saudi Arabia
The goal of this clinical trial is to learn if using the "See Yourself Differently" (syd) app can help improve quality of life and mental health for university students in Saudi Arabia.
- Conditions
- Quality of Life (QOL), Anxiety, Stress, Affect (Mental Function)
- Trial name
- NCT06979778
- Testing
- See Yourself Differently (syd) mobile app
- Where
- Saudi Arabia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- iamYiam Limited
Ischemic Stroke, Hemiplegia
Repetitive Transcranial Magnetic Stimulation for Motor Recovery After Ischemic Stroke (rTMS-MOTOR)
Ischemic stroke is a leading cause of long-term motor disability, frequently resulting in hemiplegia and limitations in daily activities and quality of life.
- Conditions
- Ischemic Stroke, Hemiplegia, Motor Function Impairment
- Trial name
- rTMS-MOTOR (NCT07369648)
- Testing
- Active repetitive transcranial magnetic stimulation, Conventional motor rehabilitation
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Hanoi Medical University
Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Alzheimer's Disease (AD) is associated with impairments in both gait and cognition, significantly increasing fall risk. Falls are a leading cause of injury-related disability in older adults, and individuals with AD experience a…
- Trial name
- NCT07659964
- Testing
- Metronome
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Autonomic Function
Understanding Individual Variability in Neuronal Signal Transmission to Target Organs in Health and Disease
The goal of this clinical trial is to evaluate the influence of parasympathetic transmission from the brain to different metabolic organs. This transmission can be blocked with the muscarinic antagonist atropine.
- Trial name
- CPB_Atropine (NCT06912048)
- Testing
- Oral glucose tolerance test with double-tracer dilution and atropine infusion
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Binge Drinking
The Brain, the Bug, and the Binge: the Interplay Between Binge Drinking, Gut Microbiota, and Brain Functioning
Adolescence and youth are periods of significant maturational changes which seems to involve greater susceptibility to disruptive events in the brain such as binge drinking (BD).
- Trial name
- NCT05946083
- Testing
- Inulin Intervention, Maltodextrin Intervention
- Where
- Portugal
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Minho
Parkinsons Disease (PD)
Exergaming for Improving Upper Limb Functions in Parkinson's Disease
Parkinson's Disease commonly results in impaired hand dexterity, reducing a patient's ability to perform activities of daily living.
- Trial name
- Exergaming (NCT07475741)
- Testing
- Exergaming, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Health Sciences Lahore
Aphasia
Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function.
To explore the mechanism of five-tone speech training in reshaping language fluency function and the clinical efficacy of aphasia language function, daily communication ability and communication efficiency based on the temporal…
- Trial name
- NCT07329751
- Testing
- Traditional Chinese Medicine Five-Tone Therapy, Melodic Intonation Training, Standard speech therapy; Routine medical treatment; Health education
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fujian University of Traditional Chinese Medicine
Obesity/Therapy
Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity
Glucagon-like peptide 1 receptor agonists (GLP-1RA), such as Ozempic and Wegovy, have been rapidly adopted for the treatment of obesity in both youth and adults.
- Trial name
- PLASTIC (NCT07021937)
- Testing
- Semaglutide 1.7mg subcutaneous
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
Stroke
Thoracolumbar Fascia Thickness in Chronic Stroke Patients
The main objective of this study was to examine the thoracolumbar fascia thickness in chronic stroke patients using objective methods and to reveal the relationship of this flexibility with balance, trunk control, trunk…
- Trial name
- NCT07107295
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara University
Mental Function
Restoration of Consciousness With Ultrasonic Deep Brain Stimulation During Anesthetic Sedation
The purpose of this study is to see if mental functions take place during different levels of anesthesia using two commonly used drug (propofol and dexmedetomidine) and will include low-intensity focused ultrasound pulsation…
- Trial name
- NCT07221539
- Testing
- Propofol for fMRI, Dexmedetomidine for fMRI, Dorsolateral prefrontal cortex (DLPFC) pulsation
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sleep, Phototherapy
Light Therapy to Improve Sleep in TBI: Sleep-active Biomarkers and Glymphatic Function
This is a clinical trial designed to examine how improved sleep through morning bright light therapy is improving downstream key physiologic processes related to brain health, i.e., mitochondrial function, systemic inflammation…
- Conditions
- Sleep, Phototherapy, Glymphatic System, Mitochondrial Dynamics
- Trial name
- GLIMPSE-LION (NCT07601841)
- Testing
- Morning Bright Light Therapy, Negative Ion Generator Therapy
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Oregon Health and Science University
Hemiparetic Cerebral Palsy
Effects Obtained at Manual Function After Applying Anodic Transcranial Direct Current Stimulation (tCDS) in Children With Spastic Hemiparetic Cerebral Palsy
Spastic Hemiparetic Cerebral Palsy (SHCP) uses to limit the manual function. Using anodic transcranial direct current stimulation, it is possible to activate certain cerebral areas depending on where the electrodes are.
- Trial name
- PeditCDS (NCT06438666)
- Testing
- Anodic Transcranial Direct Current Stimulation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Malaga
Brain Aging, Cerebrovascular Function
AKG and Brain Health in Aging
This proposal will test the hypothesis that AKG supplementation will improve NGVC responses and cognitive performance in older adults.
- Trial name
- NCT07861867
- Testing
- Calcium AKG
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Post-Concussion Syndrome
Rehabilitation in Post Concussion Syndrome
This project evaluates and quantifies the effects of an individually tailored exercise program applied to patients with long-lasting symptoms after concussion, minor traumatic brain injury, so-called Post-Concussion Syndrome…
- Trial name
- REPCon (NCT05785000)
- Testing
- Physical exercise programme as an add-on, Control patients receiving usual care
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Alzheimer's Disease
Deep Cervical Lymphovenous Anastomosis for Moderate Alzheimer's Disease
This is a multicenter, prospective, open-label, endpoint-blinded randomized controlled clinical study. We aim to evaluate the safety and efficacy of deep cervical lymphovenous anastomosis (LVA) combined with routine treatment for…
- Trial name
- LYMVA-AD (NCT07658430)
- Testing
- Deep cervical lymphovenous anastomosis (LVA), Routine Treatment
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Southwest Hospital, China
Quality of Upper Limb Function, Participation Activities
Relationship Between Upper Limb Function and Participation in Hemiplegic cp
The study will be conducted to Assess quality of upper limb function in children with hemiplegic CP. Assess participation activities of children with hemiplegic CP.
- Conditions
- Quality of Upper Limb Function, Participation Activities, Hemiplegic CP
- Trial name
- NCT07497100
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Acute Brain Injury, Mechanical Ventilation
Brain Monitoring During PEEP-Based Respiratory Therapy in Critically Ill Patients
Mechanical ventilation is commonly used in critically ill patients with acute brain injury. Positive end-expiratory pressure (PEEP) and lung recruitment maneuvers are important ventilator strategies for improving oxygenation, but…
- Conditions
- Acute Brain Injury, Mechanical Ventilation, Neurocritical Care
- Trial name
- NCT07716787
- Testing
- Recruitment Maneuver, Positive End-Expiratory Pressure Adjustment
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shengli Oilfield Hospital
Bradycardia
Impact of Allometric Pacing Rate on Ventricular Diastolic Function and Cerebral Blood Flow in Hypertensive Patients With Sinus Node Dysfunction
The study is a prospective, randomized controlled study in hypertensive patients with a bradycardia indications for pacing therapy and a plan to receive dual-chamber pacemaker.
- Trial name
- NCT07589452
- Testing
- Personalized lower rate pacing, Standard lower rate pacing
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Acute Stroke, Functional Recovery
Prognostic Recovery Observations and Guidance for Evaluating Stroke Survivors
This research delves into the acute prognostic factors influencing functional recovery in individuals who have experienced a stroke.
- Conditions
- Acute Stroke, Functional Recovery, Prognostic Factors
- Trial name
- PROGRESS (NCT06465758)
- Where
- Italy
- Volunteers
- 360 people
- Sponsor
- IRCCS San Raffaele
Chronic Headache, Nutcracker Phenomenon, Renal
Lumbar Vein Embolization for Chronic Headaches With Nutcracker Physiology
The purpose of this research is to gather information on the safety and feasibility of coiling the lumbar vein for the treatment of chronic headaches in patients with Nutcracker physiology and retrograde lumbar vein flow with…
- Conditions
- Chronic Headache, Nutcracker Phenomenon, Renal, Nutcracker Syndrome, Renal
- Trial name
- NCT06077747
- Testing
- Coil Embolization of the Lumbar Vein
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Mayo Clinic
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.