Clinical trials: Brain Health Activities
Healthy Adults
Acute Effects of Sitting and Physical Activity on Brain Health
The specific aim of this study is to understand how a working day composed of prolonged sitting, sitting regularly interrupted by light aerobic exercise or resistance exercise affects an important mechanism underpinning healthy…
- Trial name
- NCT04137211
- Testing
- Prolonged sitting with social break, Prolonged sitting with walk break, Prolonged sitting with simple resistance activities
- Where
- Sweden
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- The Swedish School of Sport and Health Sciences
Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Intervention
Healthy Eating and Active Living (HEAL), Exploring Feasibility of a Lifestyle Intervention
Lifestyle interventions combining nutrition, physical activity, and behavioral strategies are increasingly recognized for improving metabolic and psychological health, yet their translation into real-world settings remains…
- Conditions
- Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Intervention, Lifestyle Modification
- Trial name
- HEAL (NCT07662499)
- Testing
- Multimodal lifestyle intervention (HEAL program)
- Where
- United Arab Emirates
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- New York University Abu Dhabi
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Dementia, Mild Cognitive Impairment (MCI)
Combating Alzheimer's Through Sleep and Exercise
The Combating Alzheimer's through Sleep and Exercise (CASE) study is an exploratory, hypothesis-generating trial designed to: (1) assess whether improvements in sleep are associated with improvements in cognitive performance and…
- Conditions
- Dementia, Mild Cognitive Impairment (MCI), Cognitively Unimpaired, Alzheimer's Dementia (AD)
- Trial name
- CASE (NCT04855630)
- Testing
- Elemind Neuromodulation Headband, Exercise Routine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Miami
Children, Adolescents
Exercise and Endocannabinoids for Brain and Mental Health
This study will explore how exercise affects brain chemicals called endocannabinoids, which may improve thinking skills and reduce feelings of stress, anxiety, and low mood in children and teens aged 9 to 17.
- Trial name
- EMBH (NCT06808490)
- Testing
- Moderate Intensity Exercise, Light Intensity Stretching, Seated Meditation
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Dementia, Horticultural Therapy
The Effect of Horticultural Activities on Physical and Cognitive Status, Mental Well-Being, Social Participation and Quality of Life in Individuals Diagnosed with Dementia
This study aims to examine the effects of horticultural activities on the physical and cognitive status, mental well-being, social participation, and quality of life of individuals diagnosed with dementia living in nursing homes.
- Conditions
- Dementia, Horticultural Therapy, Quality of Life, Occupational Therapy
- Trial name
- NCT06899256
- Testing
- Horticultural Activity Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cerebral Palsy, Spina Bifida
Virtual Peer Health Coaching for Adolescents With Disabilities
Participation in physical activity (PA) confers clear physical and psychosocial benefits. Yet, many adolescents with physical disabilities such as cerebral palsy and spina bifida do not engage in regular PA, putting them at…
- Trial name
- NCT05587634
- Testing
- Virtual Peer Health Coaching
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Sedentary Behavior, Stroke
The Art of Moving for Sustainable Health
Sedentary behaviour is particularly high among the older and in the presence of a chronic pathology. Physical activity is limited mainly by the lack of accessibility to activities offered in the city and the lack of motivation.
- Trial name
- ART-M2 (NCT04987255)
- Testing
- Free visit, Guided visit, Guided visit (stroke)
- Where
- Switzerland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Pulmonary Disease, Headache Disorders
Smoking and Health Among University Students
The goal of this observational study is to explore the associations between pulmonary capacity, physical activity levels, and headache occurrence in university students aged 18-30, focusing on differences between smokers and…
- Conditions
- Pulmonary Disease, Headache Disorders, Sedentary Behavior, Physical Activity Level
- Trial name
- SHUS (NCT06680570)
- Testing
- Pulmonary Function Testing, Carbon Monoxide (CO) Breath Testing
- Where
- Turkey (Türkiye)
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Hypoxia, Cerebral Hypoxia
Effect of Hypoxic Conditioning on Cerebrovascular Health in the Elderly
In line with the ever-growing aging of Western populations, the development of preventive strategies to slow down the effects of aging on cardiovascular health represents a major challenge in order to preserve functional…
- Conditions
- Hypoxia, Cerebral Hypoxia, Brain Diseases, Exercise
- Trial name
- HYPOXAGE (NCT05048680)
- Testing
- Hypoxia and/or Exercise
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Hydration Status
Hydrate Heroes for Improving Brain Function & Mood
The primary goal of this 12-week randomized controlled study is to evaluate whether daily use of Hydrate Heroes results in measurable improvements in brain activity, mental health, and performance on cognitive tasks.
- Trial name
- NCT07241260
- Testing
- Hydrate Heroes (6 packets), Hydrate Heroes (3 packets)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Healthy Aging
Effect of Mindfulness on EEG Brain Activity for Cognitive and Psychological Well-being in the Elderly
As the worldwide population of older adults rapidly increases over the coming years, effective strategies are needed to help this population to maintain and enhance physical, cognitive, and psychological well-being.
- Trial name
- NCT05941143
- Testing
- mindfulness-based intervention
- Where
- Italy
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Cognitive Change, Creativity
Naturalistic Study of Microdosing With Psilocybin
This study seeks to understand the neural, cognitive and behavioral effects of low doses of psilocybin administered in the form of dried mushroom material (0.5 g of Psilocybe cubensis) consumed in natural settings following a…
- Conditions
- Cognitive Change, Creativity, Mood Change, Sleep
- Trial name
- NATMICRO (NCT05160220)
- Testing
- Psilocybin
- Where
- Argentina
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Exercise, Children
Long-term Exercise Effects from Robotic Walking
The vision of the Long-term Exercise Effects from Robotic Walking (LEER) research program is to develop optimal, individualized exercise strategies that would in turn enhance the health and well-being of non-ambulatory children…
- Conditions
- Exercise, Children, Cerebral Palsy
- Trial name
- LEER (NCT04307602)
- Testing
- Exercise - High Intensity Interval Training (HIIT), Exercise - Submaximal Steady State Training (SST)
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lund University
Healthy, Cognitive Function 1, Social
Investigating Gains in Neurocognition in an Intervention Trial of Exercise
This randomized control trial will examine whether a 12 month monitored exercise intervention improves brain health in cognitively normal older adults.
- Trial name
- IGNITE (NCT02875301)
- Testing
- 150 Minutes Week, 225 Minutes Week, Stretch and Tone
- Where
- 5 sites in United States
- Volunteers
- 648 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
COPD, Tetrahydrobiopterin Deficiency
O2 Transport and Utilization in Health and Lung Disease
Skeletal muscle dysfunction is a frequent and clinically relevant systemic manifestation of Chronic Pulmonary Obstructive Disease (COPD), which is still poorly understood.
- Conditions
- COPD, Tetrahydrobiopterin Deficiency, Oxidative Stress
- Trial name
- NCT04014712
- Testing
- Tetrahydrobiopterin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Cerebral Palsy
Telehealth Virtual Reality Gaming on Cardiometabolic Health Among Youth With Cerebral Palsy
The primary purpose of this study is to examine the preliminary efficacy of 12-weeks of home-based exercise using consumer available virtual reality gaming technology, compared with a 12 week wait-list control group.
- Trial name
- NCT05336227
- Testing
- Virtual Reality Exergaming
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Older Adults (50-90 Years), Cognition
Let's Increase Fuerza (Strength) Through Exercise and Diet
The purpose of the study is to conduct a 6-month randomized controlled trial among Latinos ages 50+ at risk for cognitive decline and compare the efficacy of a remote-delivered, culturally tailored Latin dance program and…
- Conditions
- Older Adults (50-90 Years), Cognition, Physical Activity
- Trial name
- LIFTED (NCT06884501)
- Testing
- Latin dance, MIND diet, and Strength training, Latin dance and MIND Diet
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Patient Compliance
Cognitive Regulation Training and Exercise Trial
The purpose of this double-blinded, randomized controlled study is to compare CORTEX (Cognitive Regulation Training and Exercise), a multi-faceted, center- and home-delivered- general and exercise-specific-active and traditional…
- Trial name
- CORTEX-II (NCT03124667)
- Testing
- Games, Videos
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign