Clinical trials: Brain Health Activities
Dementia
Impact of Hospital Admission on Patients With Dementia
People with dementia have complex medical, social, and psychological needs and can be exacerbated by physical illness and the complex relationships between health care systems, patients and their families or caregivers.
- Trial name
- NCT02483065
- Testing
- mortality at discharge and 3-months after the admission in patients with and without dementia
- Volunteers
- 413 people
- Sponsor
- Hospital Galdakao-Usansolo
Healthy Adults
Acute Effects of Sitting and Physical Activity on Brain Health
The specific aim of this study is to understand how a working day composed of prolonged sitting, sitting regularly interrupted by light aerobic exercise or resistance exercise affects an important mechanism underpinning healthy…
- Trial name
- NCT04137211
- Testing
- Prolonged sitting with social break, Prolonged sitting with walk break, Prolonged sitting with simple resistance activities
- Where
- Sweden
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- The Swedish School of Sport and Health Sciences
Colorectal Cancer, Older Adults (60 - 85 Years Old)
Chemo Brain Prehab Project
Colorectal cancer is 37% higher in the North West than the national average and is treated by chemotherapy, including fluorouracil, capecitabine, and oxaliplatin.
- Conditions
- Colorectal Cancer, Older Adults (60 - 85 Years Old), Physically Inactive, Chemotherapy
- Trial name
- CHEMOBRAIN (NCT07341217)
- Testing
- Exercise Prehabilitation, Multivitamins, Standard Care (in control arm)
- Where
- 4 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- Dr. Chris Gaffney
Health Behavior, Aging
B-Fit Intervention to Improve Brain Health
An accumulating body of research indicates that activities such as exercise, active cognitive and social engagement, good sleep hygiene, stress reduction and proper nutrition are associated with the maintenance of cognitive…
- Trial name
- B-Fit (NCT03454074)
- Testing
- Problem-solving, Education
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington State University
Spastic Hemiplegic Cerebral Palsy
The Effect of Mirror Therapy on Cerebral Re-organization, Functional Motor Skills, and Quality of Life in Hemiplegic Cerebral Palsy
The purpose of this study is to investigate brain reorganization, functional motor development, level of daily living activity and quality of life of upper extremity mirror therapy in children with spastic hemiplegic cerebral…
- Trial name
- NCT03612128
- Testing
- control group, intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Hacettepe University
Type 2 Diabetes, Cognitive Decline in Older Adults
Exercise and Diabetes Interventions to Improve Brain Health in Older Adults With Type 2 Diabetes
Type 2 diabetes and low levels of physical activity are associated with an increased risk of cognitive decline in older adults. Improving blood sugar control and engaging in regular exercise may help support brain health and…
- Trial name
- MOTIVATE (NCT07485062)
- Testing
- semaglutide, Moderate-Intensity Resistance Exercise, Balance and Tone (BAT) Exercise
- Where
- Canada
- Volunteers
- 164 people
- Sponsor
- Western University, Canada
Cardiology, Psychiatry
Effects of Aerobic Exercise on Cognition,Cerebral Brain Flow and Mental Health Among Traumatic Brain Injury Patients
The aim of this study is to develop exercise prescription of TBI patients and then to evaluate the effectiveness of programmed aerobic walking exercise to improve cognitive performance, depression relief, motivation, symptom…
- Trial name
- NCT04243226
- Testing
- telehealth-based aerobic walking exercise
- Where
- Taiwan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Hypoxia, Cerebral Hypoxia
Effect of Hypoxic Conditioning on Cerebrovascular Health in the Elderly
In line with the ever-growing aging of Western populations, the development of preventive strategies to slow down the effects of aging on cardiovascular health represents a major challenge in order to preserve functional…
- Conditions
- Hypoxia, Cerebral Hypoxia, Brain Diseases, Exercise
- Trial name
- HYPOXAGE (NCT05048680)
- Testing
- Hypoxia and/or Exercise
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Age-related Cognitive Decline
Resilience and Brain Health of Older Adults (MEDEX-2)
This project capitalizes on a natural experiment imposed by the COVID-19 pandemic in conjunction with an extensive set of cognitive, emotional, biological, and neuroimaging variables already collected at multiple time points in…
- Trial name
- MEDEX-2 (NCT05124132)
- Testing
- Mindfulness-Based Stress Reduction, Exercise, Mindfulness-Based Stress Reduction + Exercise
- Where
- United States
- Volunteers
- 468 people
- Sponsor
- Washington University School of Medicine
Stroke
SINEMA Model of Care to Improve the Health of Stroke Patients in Rural China
Despite the significant burden of stroke in rural China, secondary prevention of stroke is scarce. The aim of the study is to develop a system-integrated technology-enabled intervention (SINEMA) model for the secondary prevention…
- Trial name
- SINEMA (NCT03185858)
- Testing
- SINEMA intervention
- Where
- China
- Volunteers
- 1,299 people
- Sponsor
- Duke Kunshan University
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Mild Cognitive Impairment (MCI), Dementia
Exercise Workshop, Skill-Based Art Approaches, and Awareness Studies for Elderly Individuals
Purpose: The aim of the project is to contribute to the physical, social, and psychological well-being of elderly individuals with cognitive impairment within a multidisciplinary approach framework, and to increase the level of…
- Conditions
- Mild Cognitive Impairment (MCI), Dementia, Alzheimer Disease, Geriatric Rehabilitation
- Trial name
- NCT07016893
- Testing
- Healthy aging interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke
Dance as a Means to Improve Functions and Quality of Life After a Stroke
Context Dance is an intrinsically motivating activity comprising social interaction, stimulation through music, the joy of moving despite motor limitations induced by pathology, and which has good perceived benefits among…
- Trial name
- HEMI'DANCE (NCT04120467)
- Testing
- Dance, Standard rehabilitation
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- Anne-Violette Bruynnel
HIV
Exercise Training to Improve Brain Health in Older HIV+ Individuals
Management and treatment of older persons living with HIV (PLWH) (≥ 40 years old) is becoming increasingly more complex as a majority is greater than 40 years old.
- Trial name
- Ex/HIV (NCT02663934)
- Testing
- Exercise, Stretching and Social Interaction
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Washington University School of Medicine
Parkinson Disease
"Parkinson AKTIV - Non-pharmacological Treatments in an Innovative Parkinson's Network"
The purpose of this study is to evaluate the efficacy of an online platform that allows neurologists and therapists to exchange therapy recommendations, communicate assessments and plan physical therapy, occupational therapy as…
- Trial name
- ParkinsonAKTIV (NCT05251298)
- Testing
- Coordination through the online platform "JamesAKTIV"
- Where
- Germany
- Volunteers
- 370 people
- Sponsor
- University Hospital Muenster
Congenital Heart Defect, Chronic Pain
Impacting Children's Physical and Mental Health Through Kinesiology Support in Clinical Care
Over the past four decades, it has become clear that childhood physical activity carries with it a myriad of beneficial effects.
- Conditions
- Congenital Heart Defect, Chronic Pain, Concussion Post Syndrome, Cerebral Palsy
- Trial name
- NCT04106154
- Testing
- Kinesiology Support
- Where
- Canada
- Volunteers
- 111 people
- Sponsor
- Children's Hospital of Eastern Ontario
Dementia
User-Led Meaningful Activity and Early-Stage Dementia
Neuropsychiatric symptoms are the most difficult, distressing, and burdensome aspects of dementia care and a catalyst for long-term care placement.
- Trial name
- NCT05159869
- Testing
- User-Led Meaningful Activity Plan
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Johns Hopkins University
Sedentary Behavior
Cultural Pathways to Develop Sustainable Health
The 2030 Agenda for Sustainable Development, adopted by all United Nations Member States in 2015 includes the goal 3 "Ensure healthy lives and promote well-being for all at all ages".
- Trial name
- ART'M2-APP (NCT05635695)
- Testing
- Free Museum visit, Cultural pathways App
- Where
- Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Stroke
Robot-Assisted Gait Training in Early-Subacute Stroke
A stroke happens when blood flow to the brain is cut off. Many people struggle to walk after having a stroke. Regaining the ability to walk is a key aim for many stroke survivors and rehabilitation practitioners as it allows…
- Trial name
- NCT06233734
- Testing
- The Lokomat (Hocoma, Zurich, Switzerland).
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Winchester
Stroke, Hip Fractures
Outcome of Rehabilitation of Older People in Primary Health Care
The Outcome of Multi-Disciplinary, Structured Rehabilitation of Older People in a District Inpatient Rehabilitation Centre is better than in a Standard Primary Health Care Rehabilitation Programme in Short Term Beds in Nursing…
- Conditions
- Stroke, Hip Fractures, Osteoarthritis, Chronic Disease
- Trial name
- NCT01457300
- Testing
- Rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 302 people
- Sponsor
- University of Oslo