Clinical trials: Brain Injury, Acute
Stroke, Acute Traumatic Brain Injury
Clinimetric Application of FOUR Scale as in Treatment and Rehabilitation of Patients With Acute Cerebral Injury
The aim of this study is to increase the effectiveness of clinical monitoring of patients with acute cerebral insufficiency by improving the discriminative ability of the FOUR scale.
- Conditions
- Stroke, Acute Traumatic Brain Injury, Subarachnoid Hemorrhage
- Trial name
- FOURACI (NCT06043167)
- Testing
- The predictive value russian rendition the FOUR score.
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Surgut Clinical Trauma Hospital
Moderate to Severe Traumatic Brain Injury
Ante-hypophyseal Dysfunctions in Children Following Moderate to Severe Traumatic Brain Injuries
Annual incidence of severe traumatic brain injuries (TBI) varies from 180 to 300 out of 100.000. Mortality or severe sequelae risk is increased 8 fold after a TBI.
- Trial name
- Endoc-TC (NCT01250132)
- Testing
- Biological and behavioral explorations
- Where
- 2 sites in France
- Volunteers
- 110 people
- Sponsor
- Hospices Civils de Lyon
Intracranial Hemorrhages, Surgery
Evaluation of Surgery in Elderly With Traumatic Acute SubDural Hematoma
Rationale: The rapidly increasing number of elderly (≥ 65 years old) with traumatic brain injury (TBI) is accompanied by substantial medical and economic consequences.
- Trial name
- RESET-ASDH (NCT04648436)
- Testing
- Early neurosurgical hematoma evacuation, Conservative treatment (best medical management)
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Mild Traumatic Brain Injury, Concussion, Mild
Neural Injury in Adolescents With Concussion
This study utilizes multimodal brain imaging to obtain quantitative biomarkers of brain injury and to improve understanding of the biological basis of brain pathology in adolescents with concussion.
- Conditions
- Mild Traumatic Brain Injury, Concussion, Mild, Acute Brain Injury
- Trial name
- NCT03011983
- Testing
- MEG, MRI, Neuropsychology assessment
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Acute Brain Injuries
Dexmedetomidine-based Sedation in Neurocritical Care Patients
This will be an open, prospective pilot study with pharmacological analysis. This study is designed to assess the efficacity and safety of dexmedetomidine-based sedation in two subgroups of neurocritically ill patients requiring…
- Trial name
- NCT02252523
- Testing
- Dexmedetomidine
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Clermont-Ferrand
Brain Injuries, Acute
Signal Analysis for Neurocritical Patients
The project uses big data analysis techniques such as wavelet transform and deep learning to analyze physiological signals from neurocritical patients and build a model to evaluate intracranial condition and to predict…
- Trial name
- NCT03362346
- Testing
- intracranial pressure monitoring
- Where
- Taiwan
- Volunteers
- 156 people
- Sponsor
- Far Eastern Memorial Hospital
Mild Traumatic Brain Injury
Early Intervention Following Mild TBI
The objective of the study is to implement and measure the efficiency of a standardized acute and brief non-pharmacological intervention (Cognitive interventions on Sleep - Anxiety - Attention - Memory) following mild TBI and…
- Trial name
- NCT01947504
- Testing
- education and support intervention
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Elaine De Guise
Physical Fatigue, Return to Sport
The Effect of Physical Fatigue on Different Balance Tests and Brain Activity in a Healthy Population
The main objective of this project is: 1. To assess the influence of physical fatigue on brain functioning during a balance and reaction time task in a healthy population.
- Conditions
- Physical Fatigue, Return to Sport, Injury Prevention, EEG
- Trial name
- NCT04030390
- Testing
- Physical Fatigue, Control
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Dementia, Mild Cognitive Impairment
Video Games to Track Cognitive Health
The purpose of this study is to assess cognitive function using a rapid, portable, computerized neurocognitive testing device in a wide variety of clinical settings.
- Conditions
- Dementia, Mild Cognitive Impairment, Cognitive Impairment, Cognitive Decline
- Trial name
- NCT03608722
- Testing
- SLUMS, MMSE, MoCA
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- BrainCheck, Inc.
Stroke, Acute Brain Injury
Effectiveness of the Dynavision Device to Improve Spatial Awareness After Brain Injury
The purpose of this research is to determine the effectiveness of using the Dynavision D2 to improve left neglect in adults with brain injury, and improve performance of ADLs/IADLs.
- Trial name
- NCT05506241
- Testing
- Dynavision D2
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Teresa Broers
Disorder of Consciousness, Consciousness, Loss of
SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury
Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models.
- Conditions
- Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury
- Trial name
- NCT06083441
- Testing
- SeeMe, Coma Recovery Scale-Revised (CRS-R)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Subarachnoid Haemorrhage (SAH)
ALI & Pulmonary HA Deposition After SAH
Acute lung injury is a common complication of subarachnoid hematoma (SAH), and a significant risk factor for death in patients with SAH.
- Trial name
- NCT06628531
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Tianjin Medical University
Post-Concussion Syndrome
Craniosacral Therapy for Concussion Symptoms
This study investigated the utilization of CranioSacral Therapy (CST) in patients with Post-Concussion Syndrome (PCS) and capture patient-reported perceptions of their lived experiences of treatment effect upon their symptoms.
- Trial name
- NCT04820192
- Testing
- Craniosacral Therapy
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Special Therapies, Inc.
Traumatic Brain Injury
Evidence Based Diagnostics and Treatment Planning Solution for Traumatic Brain Injuries
Adult patients, age ≥ 18 years, with clinically diagnosed mild, moderate or severe brain trauma will be asked to participate in the study.
- Trial name
- NCT02021877
- Where
- 2 sites in Finland, United Kingdom
- Volunteers
- 396 people
- Sponsor
- Turku University Hospital
Aortic Dissection, Stroke
Neurological Complications and ICU Workload After Emergency Repair of Acute Type A Aortic Dissection
Single-center retrospective cohort at China Medical University Hospital (Taichung, Taiwan) using fully de-identified electronic health records.
- Conditions
- Aortic Dissection, Stroke, Paraplegia, AKI - Acute Kidney Injury
- Trial name
- ATAAD-ICU (NCT07167628)
- Where
- Taiwan
- Volunteers
- 274 people
- Sponsor
- China Medical University Hospital
Acute Brain Injury
Transcutaneous Pulse Oximetry Brain Monitoring Study (US)
This is a study of adult patients with a severe and sudden brain injury who have a drain placed in their brain to measure pressure.
- Trial name
- T-POT US (NCT06267131)
- Testing
- Brain Pulse Oximeter
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cyban Pty Ltd
Brain Injuries, Traumatic, Brain Injuries, Acute
Critical Hyperacute Assessment Research On Neurobiomarker Kinetics in Acute Brain Injury
Traumatic brain injury (TBI) and other conditions that reduce blood flow to the brain - such as cardiac arrest (CA) - are life-threatening medical emergencies.
- Conditions
- Brain Injuries, Traumatic, Brain Injuries, Acute, Hypoxia, Brain, Cardiac Arrest (CA)
- Trial name
- CHARON (NCT07782216)
- Where
- 4 sites in Hungary
- Volunteers
- 477 people
- Sponsor
- University of Pecs
Acute Renal Failure, Neonatal Morbidity
SafeBoosC-IIIv - Does Cerebral Oximetry Monitoring Affect Renal Outcomes
Cerebral oximetry monitoring allows clinicians to optimize blood flow to the brain and oxygenation using the SafeBoosC treatment guideline. The guideline's interventions aims to stabilize blood pressure and oxygen levels.
- Trial name
- SBIIIvR (NCT06926946)
- Testing
- Intervention Arm- Cerebral Oximetry + Treatment Guideline
- Where
- India
- Volunteers
- 1,000 people
- Sponsor
- St. John's Research Institute
Brain Concussion
The s100β Levels in Patients With Mild Brain Injury.
Mild traumatic brain injury (TBI) accounts for the majority of TBI. At present, whether TBI has traumatic intracranial lession is mainly diagnosed by computed tomography (CT), while only 5% of mild TBI has positive CT results.
- Trial name
- NCT06131242
- Testing
- It is an observational study
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Sumei Lu