Clinical trials: Brain Neoplasm
Pediatric Solid Tumor, Pediatric Brain Tumor
Effects of Music and Maternal Voice on Sedation Depth and Sedative Use During Pediatric Magnetic Resonance Imaging.
To evaluate the effects of music and maternal voice in children on sedation depth and sedative use during pediatric magnetic resonance imaging.
- Conditions
- Pediatric Solid Tumor, Pediatric Brain Tumor, Pediatric Cancer
- Trial name
- NCT04944875
- Testing
- Group headphone, Group music, Group maternal voice
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Breast Cancer
Chemotherapy Effect on Brain Structure, Neurophysiology and Psychomotor Behavior in Breast Cancer Patients
Some cancer patients report experiencing mild problems with thinking during or following chemotherapy. Symptoms include problems concentrating, slow thinking, some gaps in memory and difficulty performing complex or multi-tasks.
- Trial name
- NCT02896504
- Testing
- Exposure: Adjuvant chemotherapy treatment, Exposure: Adjuvant hormonal therapy treatment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Parkinson's Disease, Alzheimer's Disease
Biomarkers in Neural Disorders
This study seeks to establish the sensitivity and specificity of what appears to be a unique brainstem biomarker of Parkinson's Disease (PD) - an electrically induced olygosynaptic nasotrigeminal reflex response - in…
- Conditions
- Parkinson's Disease, Alzheimer's Disease, Progressive Supranuclear Palsy, Essential Tremor
- Trial name
- NCT02761707
- Testing
- Electrical Brainstem Responses, Olfactory Tests, Visual Deprivation
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pituitary Adenoma, Nonfunctioning Pituitary Adenoma
Cabergoline in Nonfunctioning Pituitary Adenomas
Clinically nonfunctioning pituitary adenoma remains the only pituitary tumor subtype for which no effective medical therapy is available or recommended.
- Trial name
- NCT03271918
- Testing
- Cabergoline
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Brain Neoplasms, Malignant, Metastasis
CEST- Glucose Enhanced MRI for Metastatic Brain Tumours
This project will compare two MRI contrast agents in metastatic brain tumours in humans. More specifically, the investigators will compare the tumour contrast obtained using glucose versus the current standard gadolinium-based…
- Trial name
- NCT02796729
- Testing
- Magnetic resonance imaging, Gadovist (Gadobutrol), 50% dextrose solution
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Brain Tumors
Presurgical Planning With Functional MRI (fMRI) Mapping of Motor Cortex in Patients With Cerebral Tumors
The purpose of this study is to determine if functional MRI is precise enough to provide information about the location of brain functions in patients who have brain tumors.
- Trial name
- NCT00724737
- Testing
- Presurgical MRI, functional MRI (fMRI) of the brain
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Prolactinoma
Exercise Capacity and Physical Activity Level in Prolactinoma Patients
Prolactinoma, one of the most common pituitary adenomas, is an adenoma that causes excessive prolactin (PRL) secretion. An increase in prolactin level can cause weakness, decrease in muscle mass and fatigue.
- Trial name
- NCT05236829
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Myocardial Infarction, Ischemic Stroke
Emulation of the Moderate Alcohol and Cardiovascular Health Trial (MACH15)
The aim of this study is to assess how long-term alcohol consumption influences health risks by emulating the Moderate Alcohol and Cardiovascular Health Trial (MACH15).
- Conditions
- Myocardial Infarction, Ischemic Stroke, Angina Pectoris, Coronary Revascularization
- Trial name
- NCT06583161
- Testing
- Moderate drinking, Quitting, Social drinking
- Volunteers
- 503,325 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Diabetes (DM), Cardio Vascular Disease
Nut Consumption and Prevention of Non-communicable Diseases: A Global Individual Participant Data Meta-analysis
The relationship between nut consumption and the risk of developing non-communicable diseases (NCDs) has been a subject of growing interest.
- Conditions
- Diabetes (DM), Cardio Vascular Disease, Cancer, Dementia
- Trial name
- NUTPOOL (NCT07205978)
- Where
- 2 sites in Denmark, Spain
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Non-small Cell Lung Cancer Stage II, Bevacizumab
Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases
A multicenter, single-arm, open study to evaluate the safety and efficacy of Serplulimab in combination with bevacizumab and first-line chemotherapy in driver negative non-squamous NSCLC patients with brain metastases
- Conditions
- Non-small Cell Lung Cancer Stage II, Bevacizumab, Immunotherapy, Brain Metastases
- Trial name
- SUPER BRAIN (NCT05807893)
- Testing
- Serplulimab combined with bevacizumab and first-line chemotherapy
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Cancer, Brain Tumor
A Study of Therapeutic Amplitude-modulated Electromagnetic Fields in Advanced Tumors
In vitro studies suggest that low levels of amplitude-modulated electromagnetic fields may modify cell growth. We have identified specific frequencies that may block cancer cell growth.
- Trial name
- THBC001 (NCT00440570)
- Testing
- Low levels of amplitude-modulated electromagnetic fields, Emitter of low levels of amplitude-modulated electromagnetic fields
- Where
- Switzerland
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Pasche, Boris, M.D.
Dementia, Mild, Accidental Falls
Development of Pressure Sensor Based Dementia and Fall Prevention Program for Older Adults
The goal of this intervention program is to test the effectiveness of pressure sensor based dementia and fall prevention program for improving cognitive and physical functions of community dwelling older adults.
- Conditions
- Dementia, Mild, Accidental Falls, Mild Cognitive Impairment
- Trial name
- NCT06664229
- Testing
- Fall and dementia prevention exercise
- Where
- South Korea
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Sunmi Song
Anaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor
Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer
This phase I trial investigates the side effects and effectiveness of chemotherapy followed by a donor (allogeneic) stem cell transplant when given to patients with high grade brain cancer.
- Conditions
- Anaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor, Central Nervous System Germ Cell Tumor, Choroid Plexus Carcinoma
- Trial name
- NCT04521946
- Testing
- Etoposide, Fludarabine Phosphate, Hematopoietic Cell Transplantation
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Primary Brain Tumor, Neurocognition
Executive and Socio-cognitive Functions in Survivors of Primary Brain Tumor: Impact on Patients' Quality of Life
Significant advances in primary malignant brain tumors (PBT) treatment have led to dramatically improved survival, both in children and adults.
- Conditions
- Primary Brain Tumor, Neurocognition, Quality of Life
- Trial name
- NEUROCOG-QOL (NCT02693405)
- Testing
- Executive functions, social cognition, quality of life
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Neurofibromatosis Type 1, Brain Tumor
Feasibility and Clinically Application of Magnetic Resonance Fingerprinting
This study will look at the feasibility of using magnetic resonance fingerprinting (MRF) in children, adolescents and young adults (AYA) with and without brain tumors.
- Conditions
- Neurofibromatosis Type 1, Brain Tumor, Glioma
- Trial name
- NCT02387840
- Testing
- Magnetic Resonance Imaging, Magnetic Resonance Fingerprinting
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer, Chemotherapeutic Agent Toxicity
Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer
RATIONALE: Gathering information over time from laboratory tests, imaging scans, and assessment tests may help doctors learn more about the side effects of chemotherapy and plan the best treatment.
- Conditions
- Breast Cancer, Chemotherapeutic Agent Toxicity, Cognitive/Functional Effects, Fatigue
- Trial name
- NCT00755313
- Testing
- trastuzumab, aromatase inhibition therapy, carboplatin
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC