Clinical trials: Brain Stimulation
Parkinson's Disease, Depression
Magnetic Stimulation for Parkinson Disease
During transcranial magnetic stimulation (TMS), a magnetic coil is placed on the front part of the head. Electric current passes through the coil in brief pulses.
- Trial name
- NCT00029276
- Testing
- Prefrontal transcranial magnetic brain stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
PARKINSON DISEASE (Disorder)
TIS for Brain Network Modulation and Clinical Efficacy in Parkinson's Disease
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction. While deep brain stimulation (DBS) is effective, its invasive nature limits its application in early-stage patients.
- Trial name
- PD TIS (NCT07480317)
- Testing
- Temporal Interference Stimulation (130 Hz), Temporal Interference Stimulation (40 Hz)
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Jiangsu Province Nanjing Brain Hospital
Alzheimer's Disease
Deep Brain Stimulation for the Treatment of Alzheimer's Disease
The purpose of this clinical study is to investigate the safety and efficacy of deep brain stimulation (DBS)as a treatment option for patients with cognitive, behavioral, and functional disability of Alzheimer's disease.
- Trial name
- NCT01559220
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Ali Rezai, MD
Stroke
Cerebral Reorganization of Stroke Patients After Repetitive Transcranial Magnetic Stimulation by Neuroimaging Analysis
The study aimed to figure out brain structural and functional reorganization evidence after repetitive transcranial magnetic stimulation through the method of neuroimaging brain network analysis, such as resting-state functional…
- Trial name
- NCT03163758
- Testing
- real Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Peking Union Medical College Hospital
Parkinson's Disease
A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous Peripheral Nerve Tissue Into the Brain for Non-motor or Motor Symptoms in Patients With Parkinson's Disease Undergoing DBS Surgery
The investigators propose a Phase I single surgical-center, double-blinded randomized parallel clinical trial involving bilateral autologous peripheral nerve tissue (PNT) delivery into the NBM or the alternate target also…
- Trial name
- STAR (NCT06683378)
- Testing
- Reparative Autologous peripheral nerve tissue
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Craig van Horne, MD, PhD
Psychopathy
Effects of Transcranial Magnetic Stimulation on Social Cognition, Cognitive Processing, and Functional Brain Architecture
This clinical trial will examine whether transcranial magnetic stimulation (TMS), a noninvasive form of brain stimulation, can influence social cognition, cognitive processing, and brain function in adults with elevated…
- Trial name
- NCT07635940
- Testing
- continuous theta burst stimulation (cTBS), Intermittent theta burst stimulation (iTBS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Ischemic Stroke, Vagus Nerve Stimulation
Effect Of Robotic Rehabilitation And Vagus Nerve Stimulation In Ischemia Stroke Patients
This study was conducted in patients with ischemic stroke; This study was conducted to examine the effect of robotic rehabilitation and transcutaneous auricular vagal nerve stimulation applied in addition to robotic…
- Conditions
- Ischemic Stroke, Vagus Nerve Stimulation, Robotic Rehabilitation, Autonomic Nervous System
- Trial name
- ERRVNS (NCT06381089)
- Testing
- Robotic Rehabilitation, Transcutaneous Auricular Vagal Nerve Stimulation
- Volunteers
- 40 people
- Sponsor
- SEFA HAKTAN HATIK
Epilepsy
Non-interventional Study Describing Healthcare Resource Utilisation and Clinical Outcomes Associated With VNS Therapy in UK.
This is a UK, multi-center, non-interventional study based on the use of health service administrative and medical records (paper-based and/or electronic, as applicable) along with the use of prospectively collected…
- Trial name
- DANTE (NCT04779814)
- Where
- 5 sites in United Kingdom
- Volunteers
- 97 people
- Sponsor
- LivaNova
Stroke, Acute
Hemodynamic Response and Motor Functions Following Transcranial Direct Current Stimulation in Acute Stroke
The aim of the present study is to evaluate the possible effect of using dual-tDCS applied before conventional physical therapy on motor functions and hemodynamic response
- Trial name
- NCT04051658
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Mahidol University
Parkinson's Disease
Deep Brain Stimulation for Parkinson's Disease Trial
The purpose of this trial is to evaluate the effect of deep brain stimulation in the the globus pallidus (Gpi) and the subthalamic nucleus (STN) on motor, neuropsychological and psychiatric function, and quality of life in…
- Trial name
- NCT00053625
- Testing
- deep brain stimulation
- Where
- 2 sites in United States
- Volunteers
- 123 people
- Sponsor
- University of Minnesota
Parkinson Disease
Electrical Vestibular Nerve Stimulation (VeNS) in the Management of Parkinson's Disease
Parkinson's disease burdens an increasing number of elderly populations in the country. Parkinson disease is a chronic, progressive neurodegenerative disorder, affects approximately 1% of the population by the age of 65 years and…
- Trial name
- NCT04450550
- Testing
- VeNS device
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Ataxia, Cerebellar
Neuromodulation of Social Skills in Childhood Ataxia
The present study aims to define a protocol of electrical stimulation of the cerebellum via transcranial direct current stimulation (tDCS) combined with a virtual reality protocol to assist the rehabilitation of social skills in…
- Trial name
- NCT04297540
- Testing
- Active-tDCS group
- Volunteers
- 30 people
- Sponsor
- IRCCS Eugenio Medea
Parkinson
Effects of Deep Brain Stimulation for the Treatment of Parkinson's Disease
The purpose of this study is to assess the effects of unilateral deep brain stimulation on upper and lower extremity motor function in advanced Parkinson's disease patients.
- Trial name
- NCT00358189
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- US Department of Veterans Affairs
Stroke, Ischemic, Aphasia
pBFS-guided cTBS Over the Superior Temporal Gyrus for Aphasia After Ischemic Stroke
The objective of this trial is to evaluate the effectiveness and safeness of continuous Theta Burst Stimulation (cTBS) over the right Superior Temporal Gyrus (STG), guided by personalized Brain Function Sector (pBFS) technology…
- Trial name
- NCT05999318
- Testing
- active continuous Theta Burst Stimulation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Changping Laboratory
Tourette's Syndrome, Tourette Syndrome
Subthalamic Stimulation in Tourette's Syndrome
The main objective of this project is to evaluate the efficacy of subthalamic nucleus deep brain stimulation (STN DBS) in treating motor and phonic tics in medically refractory Tourette's syndrome (TS).
- Conditions
- Tourette's Syndrome, Tourette Syndrome, Gilles de la Tourette Syndrome, Tourette Disorder
- Trial name
- STN-DBSinTS (NCT02619084)
- Testing
- STN DBS
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Chronic Pain, Osteoarthritis
Effects of tDCS and tUS on Pain Perception in OA of the Knee
The purpose of this study is to investigate the effects of transcranial direct current stimulation (tDCS) in conjunction with transcranial ultrasound (TUS) on pain perception and functional limitations in people with…
- Trial name
- NCT02330315
- Testing
- transcranial direct current stimulation (tDCS), transcranial ultrasound (TUS)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Spaulding Rehabilitation Hospital
Transcranial Magnetic Stimulation
Effects of Repetitive Transcranial Magnetic Stimulation on Cerebral Autoregulation in Patients With Acute Ischemic Stroke
The purpose of this study was to investigate the effect of repetitive transcranial magnetic stimulation on cerebral autoregulation in patients with acute ischemic stroke.
- Trial name
- NCT05843240
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Yi Yang
Stuttering, Adult, Stuttering, Childhood
Transcranial Alternating Current Stimulation (tACS) in Stuttering
The purpose of this study is to investigate how mild, noninvasive electrical brain stimulation affects speech relevant brain areas, which may in turn affect speech fluency and speaking-related brain activity in people that…
- Conditions
- Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
- Trial name
- NCT06740968
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Orofacial Pain
The Use of tDCS in the Orofacial Pain
The trial´s main goal is to explore the use of transcranial direct current stimulation (tDCS) as a treatment option for persons suffering from orofacial pain.
- Trial name
- NCT05584384
- Testing
- Transcranial Direct Current Stimulation
- Sponsor
- Charles University, Czech Republic
Cortical Excitability, Brain Stimulation
Cortical Excitability and Role of Non Invasive Brain Stimulation in ADHD and AUTISM
This double-blind, randomized, sham-controlled clinical trial will evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on children and adolescents with attention-deficit/hyperactivity disorder (ADHD) or…
- Conditions
- Cortical Excitability, Brain Stimulation, ADHD, Autism
- Trial name
- NCT07315217
- Testing
- Active repetitive transcranial magnetic stimulation (rTMS)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
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