Clinical trials: Brain Stroke
Stroke Rehabilitaion, Stroke
Investigating the Efficacy of Combining Virtual Reality-Based Mirror Therapy (VRMT) and Transcranial Direct Current Stimulation (tDCS) to Improve Upper Limb Recovery in Patients with Stroke
This study will investigate whether combining virtual reality-based mirror therapy (VRMT) and transcranial direct current stimulation (tDCS) alongside conventional physical therapy (CPT) will significantly improve hand function…
- Trial name
- tDCS (NCT06764797)
- Testing
- Transcranial Direct Current Stimulation, Virtual reality, Transcranial Direct Current Stimulation compined with virtual reality based mirror therapy
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 300 people
- Sponsor
- King Saud University
Acute Stroke
A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients
Stroke is the leading cause of premature death and disability, and early recognition and treatment of dysphagia is fundamental to stroke management.
- Trial name
- NCT05454397
- Testing
- Observational study, no intervention
- Where
- 34 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Stroke Sequelae, Cognitive Impairment
Remote Bimanual Virtual Rehabilitation Post CVD
The aim of the study is to develop the BrightBrainer G (grasp), a game-based upper-extremity motor and cognitive rehabilitation system using custom virtual reality simulations.
- Conditions
- Stroke Sequelae, Cognitive Impairment, Depression
- Trial name
- NCT04713384
- Testing
- Integrative tele-rehalitation of chronic stroke survivors using custom therapeutic games
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Grigore Burdea
Stroke
Reaching Training Based on Robotic Hybrid Assistance for Stroke Patients
Stroke is the third most common cause of death and the main cause of acquired adult disability in high-income countries. The most common deficit after stroke is motor impairment of the contralateral arm, with more than 80% of…
- Trial name
- RETRAINER-S1 (NCT03171649)
- Testing
- RETRAINER-S1, Conventional therapy
- Where
- 2 sites in Germany, Italy
- Volunteers
- 68 people
- Sponsor
- Villa Beretta Rehabilitation Center
Atrial Fibrillation, Stroke
Long-term, Open-label Follow-up Treatment of Patients With A-fib Who Have Been Previously Treated With BIBR 1048
To determine the long term safety and efficacy of BIBR 1048 in patients with chronic atrial fibrilla tion, with or without concomitant chronic treatment with acetylsalicylic acid (ASA).
- Trial name
- NCT00157248
- Testing
- dabigatran etexilate
- Where
- 50 sites in United States, Denmark and 2 more
- Volunteers
- 361 people
- Sponsor
- Boehringer Ingelheim
Traumatic Brain Injury, Cerebrovascular Accident (CVA)
Managing Dysexecutive Syndrome (DS): CIHR 2011-2014
Successful community participation following acquired brain injury (ABI) continues to be an elusive goal for patients, clinicians and researchers.
- Conditions
- Traumatic Brain Injury, Cerebrovascular Accident (CVA), Acquired Brain Injury
- Trial name
- NCT01414348
- Testing
- Conventional rehabilitation., Novel rehabilitation approach
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- Baycrest
Stroke, Cognitive Impairment
Tele-Rehabilitation vs Conventional Rehabilitation for Cognitive Improvement in Stroke Survivors.
This study aims to: Compare tele-rehabilitation and conventional rehabilitation for cognitive improvement after stroke. Evaluate changes in cognitive function using standardized assessment tools.
- Conditions
- Stroke, Cognitive Impairment, Post-Stroke Cognitive Impairment
- Trial name
- NCT07504276
- Testing
- Tele-rehabilitation, Conventional Rehabilitation
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Intracranial Pressure, Traumatic Brain Injury
NIMI-NICU: Non Invasive Monitoring of the Intracranial Pressure - NeuroIntensive Care Unit
In clinical practice, intracranial pressure (ICP) represents a key parameter for diagnosing and treating several conditions. Physicians having to manage cases of head trauma, stroke and hydrocephalus need to assess the time…
- Conditions
- Intracranial Pressure, Traumatic Brain Injury, Stroke, Intracranial Hemorrhages
- Trial name
- MINIPIC REA (NCT01685476)
- Testing
- Echodia® hand-held equipment
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Stroke, Fatigue
Does Cardiorespiratory Interval Training Improve Post-stroke Fatigue
Post-stroke fatigue is common and negatively influences post-stroke recovery. Today, there is insufficient evidence how to treatment post-stroke fatigue.
- Trial name
- NCT03458884
- Testing
- Cardiorespiratory interval training
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Umeå University
Cerebral Infarction
Multi-modality MRI Study on Effect to Collateral Circulation and Blood Perfusion of Acute Cerebral Infarction by Human Urinary Kallidinogenase
Human urinary kallidinogenase can promote the establishment of collateral circulation in the ischemic penumbra due to the stenosis or occlusion of middle cerebral artery and then increase the perfusion.
- Trial name
- NCT02259738
- Testing
- Human Urinary Kallidinogenase, Shuxuening injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- XuanwuH 2
Cerebrovascular Accident
Effects of RAT in Sequential Combination With CIT in Stroke Rehabilitation
The findings of this project will contribute to the understanding of a comprehensive probe for investigation of the effects of monotherapy versus combination rehabilitation intervention after stroke, including the topics of…
- Trial name
- NCT01727648
- Testing
- RT in sequential combination with dCIT, Distributed Constraint-Induced Therapy, Robot-Assisted Therapy
- Where
- Taiwan
- Volunteers
- 92 people
- Sponsor
- National Taiwan University Hospital
Ischemic Cerebrovascular Accident
Clopidogrel for Acute Ischaemia of Recent Onset
Evaluate the role of loading Clopidogrel in acute ischemic stroke in improving neurological outcome of stroke in cases patients will be non-eligible for, or declined, treatment with or intravenous thrombolysis with rTPA, rTPA is…
- Trial name
- CAIRO (NCT02776540)
- Testing
- Clopidogrel, Aspirin
- Where
- Egypt
- Volunteers
- 188 people
- Sponsor
- Ain Shams University
Vojta Therapy, Reflex Locomotion
Vojta Therapy in Early Stroke Rehabilitation
Stroke is the major cause for permanent disability in adults. It is still unclear, which physiotherapeutic approaches are most effective.
- Trial name
- NCT03035968
- Testing
- Vojta therapy, conventional physiotherapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Corina Epple
Vascular Disease, Vascular Disease Risk
Effect of Atorvastatin (Lipitor) on Gene Expression in People With Vascular Disease
This study will determine if the drug Atorvastatin (Lipitor) changes the genetic material found in blood cells of people with vascular (blood vessel) disease.
- Trial name
- NCT00293748
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
High Risk of Stroke
Oriental Intervention for Enhanced Neurocognitive Health (Orient) Diet in Populations With High Risk of Stroke (ENDS)
This randomized controlled trial will enroll 160 individuals aged over 40 without dementia who are at high risk of stroke, collecting multi-modal MRI imaging, serum, and fecal samples to investigate the impact of the ORIENT diet…
- Trial name
- NCT06098235
- Testing
- Usual Diet advice, ORIENT diet intervention
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Ischemic Stroke
A Feasibility Study for the DAISe EZ Thrombectomy Device - Pacific
The study is a prospective, multi-center, single arm, feasibility study that will enroll a maximum of 20 subjects. A maximum of 5 investigational centers in Australia will participate.
- Trial name
- NCT06042335
- Testing
- DAISe EZ
- Volunteers
- 20 people
- Sponsor
- MIVI Neuroscience, Inc.
Recognition of Thrombectomy Candidate
Implementation of Finnish Prehospital Stroke Scale to Emergency Medical Services
The investigators have developed a simple prehospital stroke scale (FPSS), containing 5 dichotomized items to recognize both large and small artery thrombi of the brain.
- Trial name
- NCT03520335
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Tampere University Hospital
Stroke
New Tool to Enhance Post-stroke Upper Extremity Disability
Individuals with low socioeconomic status (SES) are more likely to have a stroke, more disabled at 3 months, and less likely to be independently ambulatory.
- Trial name
- NCT05277389
- Testing
- START - Startle Adjuvant Rehabilitation Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Arizona State University
Bleeding, Ischemic Stroke
The Relationship Between Clotting Factor VIII and Bleeding Adverse Reactions in Patients Under the Therapies of Thrombolysis, Anticoagulation and Anti-platelet
The purpose of this study is to determine whether Plasma Factor VIII Levels are related to the treatment of bleeding in ischemic stroke（IS）.
- Trial name
- NCT02677818
- Where
- China
- Sponsor
- Zhujiang Hospital
Stroke
Diaphragm Function and Urinary Incontinence in Stroke
Stroke affects respiratory functions by causing structural and strength impairments in both inspiratory and expiratory respiratory muscles.
- Trial name
- NCT07048210
- Volunteers
- 50 people
- Sponsor
- Istinye University
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