Clinical trials: Brain Vascular Function
Stroke, Post-Stroke Hemiparesis
Evaluation of a Wearable Exoskeleton for Functional Arm Training
The purpose of this study is to investigate how the cable-driven arm exoskeleton (CAREX) can assist task performance during 3D arm movement tasks under various experimental conditions in healthy individuals and patients with…
- Trial name
- NCT02726204
- Testing
- Gravity Elimination Alone, Path Assistance Alone, Path Assistance and Gravity Elimination
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Stroke, Acute Stroke
The Effects of Gait Rehabilitation After Stroke by Treadmill-based Robotics Versus Traditional Gait Training
This multicenter non-randomized controlled trial aims to investigate the effectiveness (an increase of the walking speed in the 10 Meter Walk Test - 10MWT) of the robotic treatment with exoskeleton or end-effector system compared…
- Conditions
- Stroke, Acute Stroke, Chronic Stroke
- Trial name
- TREAD_STROKE (NCT03688165)
- Testing
- Treadmill-based Robotic Gait Training, Traditional Over-ground Gait Training
- Where
- 4 sites in Italy
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Cerebral Vascular Accident (CVA)/Stroke
The Natural History of Recovery After Stroke
The goal of this longitudinal observational study is to learn the course of recovery after stroke. Specifically, in this study we will learn and describe the changes in cognitive, motor and sensory function over time in stroke…
- Trial name
- RESTRO (NCT06441552)
- Testing
- non-interventional
- Where
- 3 sites in Israel, Palestinian Territories
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Adi Negev-Nahalat Eran
Stroke
Upper Limb Training Modalities in Patients With Stroke
To date, evidence of the effects of robotic training combined with OnabotulinumtoxinA focal treatment for spasticity is limited.
- Trial name
- NCT03590314
- Testing
- Experimental group - robot assisted arm training (Armotion®), Control group - conventional treatment
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Cerebrovascular Accident
Ischemic Nerve Block to Improve Hand Function in Stroke Patients
This study will determine whether impaired hand function due to stroke can be improved by blocking nerve impulses to the unaffected arm.
- Trial name
- NCT00056706
- Testing
- Transient deafferentation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Instrumental Gait Analysis on People With Stroke After Rehabilitation With a Synchronized FES and Cycle Ergometer System
Functional electrical stimulation is a modality of motor rehabilitation that consists of the programmed application of bursts of electrical current to the affected neuromuscular region that aims to improve muscle strength…
- Trial name
- NCT04473391
- Testing
- Cycle-ergometer training assisted by FES for lower extremities
- Where
- Chile
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
Stroke, Healthy Health Care Professionals
Usability and Acceptability Study of a Functional Electro-stimulator Controlled by Electromyographic Signal (FitFES)
Functional recovery of the upper limb after a cerebral stroke is one of the major critical issues in rehabilitation. The advent of innovative technologies can be helpful to rehabilitators and intervene where there is no other…
- Trial name
- NCT06763874
- Testing
- EMG-based FES device
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Muscle Spasticity
Upper-limb Active Function and Botulinum Toxin A
This study in an observational, prospective and longitudinal study. The aim of the study is to evaluate the effect of botulinum toxin type A (BTX) injections into the elbow flexors on the reduction of spastic co-contractions…
- Conditions
- Stroke, Muscle Spasticity, Upper Extremity Paralysis
- Trial name
- ULAFBoT-Stroke (NCT03783572)
- Testing
- Clinical evaluation, Clinical evaluation and Instrumental evaluation
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Aphasia
Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function.
To explore the mechanism of five-tone speech training in reshaping language fluency function and the clinical efficacy of aphasia language function, daily communication ability and communication efficiency based on the temporal…
- Trial name
- NCT07329751
- Testing
- Traditional Chinese Medicine Five-Tone Therapy, Melodic Intonation Training, Standard speech therapy; Routine medical treatment; Health education
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fujian University of Traditional Chinese Medicine
Aging
Role of Flavanols In Cardiovascular Function in Healthy Aging
Groups of naturally occurring compounds called flavonoids are found in foods such as fruits and vegetables, red wine, tea, dark chocolate and cocoa products.
- Trial name
- NCT01395277
- Testing
- High Flavanol first then Low Flavanol, Low Flavanol first then High Flavanol
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Stroke
Ultrasonographic Evaluation of Morphological and Functional Characteristics of Intercostal Muscles in Stroke Patients and Their Relationship With Clinical Parameters
The aim of this study is to evaluate the morphological and functional characteristics of parasternal intercostal muscles in patients with stroke using ultrasonography.
- Trial name
- NCT07670585
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Marmara University
Cardiovascular Diseases, Hypertension
Peanuts and Neurocognitive / Cardiovascular Health in Black Individuals
The overall research objective of this proposal is to determine the impact of increased daily peanut consumption on indices of neurocognitive and physiological health in BL individuals
- Conditions
- Cardiovascular Diseases, Hypertension, Cognitive Decline, Diet
- Trial name
- NCT06318377
- Testing
- Peanut group
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Stroke
Study on the Correlation Between Neurotrophic Factors and the Condition of Stroke Patients
Stroke is currently the most common disabling disease, which often leads to impairment of sensory, motor, speech and psychological functions, resulting in a reduced quality of life for patients.
- Trial name
- NCT05479903
- Testing
- acupuncture, computerized cognitive training system, aerobic exercise
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chongqing Medical University
Stroke, Stroke (CVA) or TIA
The Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3)
Stroke is a major cause of death and disability worldwide, frequently resulting in persistent cognitive deficits among survivors.
- Conditions
- Stroke, Stroke (CVA) or TIA, Dementia, Vascular, Cerebrovascular Disorders
- Trial name
- IC3 (NCT05885295)
- Testing
- MRI brain, Blood tests, cognitive assessments
- Where
- United Kingdom
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Stroke, Vascular Diseases
Passive Limb Movement Study
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance.
- Conditions
- Stroke, Vascular Diseases, Ischemic
- Trial name
- PLM (NCT05935670)
- Testing
- Ischemic Conditioning
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Ischemic Stroke
Immunological Biomarkers in Patients With Acute Ischemic Stroke
Stroke is accompanied by local inflammatory response and systemic immunosuppression. Immunosuppression markers are associated with the occurrence of medical complications (infections), whereas inflammatory markers are associated…
- Trial name
- NCT01894529
- Where
- Spain
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Stroke
Effect of Cognitive-Motor Dual-Task Training on Postural Stability and Functional Mobility in Stroke
This Randomized Controlled Trial is conducted to investigate the effects of Cognitive-Motor Dual-Task Training on Postural Stability and Functional Mobility in Stroke Survivors.
- Trial name
- NCT07629856
- Testing
- Cognitive-motor dual-task training (CMDT) Group, Conventional Balance Training
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stroke, Cerebellum
Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke
The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes.
- Trial name
- NCT06458153
- Testing
- Neural responses to speech functional localizer, Neural responses to silent articulation, Neural responses to self vs. externally generated speech
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Stroke
Thoracolumbar Fascia Thickness in Chronic Stroke Patients
The main objective of this study was to examine the thoracolumbar fascia thickness in chronic stroke patients using objective methods and to reveal the relationship of this flexibility with balance, trunk control, trunk…
- Trial name
- NCT07107295
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara University
Stroke Patient
Mirror Therapy Versus Repetitive Facilitation Exercise on Upper Limb Function
The objective of the study is to determine the effects of Mirror therapy on upper limb function in a post-stroke patient, To determine the effects of Repetitive Facilitation Exercise on upper limb function in a post-stroke…
- Trial name
- NCT04468945
- Testing
- mirror box therapy, Repetitive Facilitation Exercise
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University