Clinical trials: Brain-Computer Interface
Peripheral Facial Palsy, Pulsed Radiofrequency
Non-Invasive Brain-Computer Interface Combined With Transcranial Electrical Stimulation for Peripheral Facial PalsyStimulation in the Treatment of Peripheral Facial Palsy
To evaluate the efficacy and safety of treating peripheral facial palsy using a non-invasive brain-computer interface combined with transcranial direct current stimulation (tDCS).
- Conditions
- Peripheral Facial Palsy, Pulsed Radiofrequency, Brain-Computer Interface, Transcranial Direct Current Stimulation
- Trial name
- NCT07327710
- Testing
- Brain-Computer Interface （BCI）, Pulsed Radiofrequency （PRF）, Standard Therapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanjing Medical University
Functional Neurological Disorder, Conversion Disorder
Brain-computer Interface Rehabilitation And Virtual Environments in Functional Neurological Disorder (BRAVE-FND)
The purpose of this study is to determine whether a course of rehabilitation using a device called a brain-computer interface can change the level of control people feel over bodily movements, in functional neurological disorder.
- Conditions
- Functional Neurological Disorder, Conversion Disorder, Functional Neurological Disorders, Conversion Disorder With Weakness/Paralysis
- Trial name
- BRAVE-FND (NCT07006415)
- Testing
- Brain-computer interface rehabilitation
- Volunteers
- 24 people
- Sponsor
- King's College London
Stroke Sequelae, Motor Disorders
Clinical Validation of a Hybrid BCI-controlled FES for Upper Limb Rehabilitation After Stroke
The RECOMMENCER project aims at developing and testing a novel hybrid Brain Computer Interface device based on cortico-muscular connectivity, that will be employed to activate Functional Electrical Stimulation (FES) of upper limb…
- Trial name
- RECOMMENCER (NCT05511207)
- Testing
- RECOM - hBCI training, CTRL - upper limb training with FES
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Donatella Mattia
Amyotrophic Lateral Sclerosis, Neuromuscular Disease
Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)
The Connect-One Study is an early feasibility study to obtain preliminary device safety information for the Connexus Brain-Computer Interface (BCI).
- Conditions
- Amyotrophic Lateral Sclerosis, Neuromuscular Disease, Stroke, Tetraplegia/Tetraparesis
- Trial name
- CONNECT-ONE (NCT07357428)
- Testing
- Connexus Brain-Computer Interface
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Paradromics
Laryngeal Dystonia
Brain-Computer Interfaces in Laryngeal Dystonia
The researchers will develop and evaluate the use of adaptive closed-loop brain-computer interface therapeutic intervention in laryngeal dystonia.
- Trial name
- NCT04421365
- Testing
- neurofeedback brain-computer interface (BCI)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kristina Simonyan
Depressive Sympotoms
Real-Time EEG Neurofeedback Using a Subject-Independent Classifier in Women With Depressive Symptoms
This completed feasibility study examined whether right-handed women aged 18-35 years with mild-to-moderate depressive symptoms could use real-time electroencephalography (EEG) neurofeedback based on a subject-independent…
- Trial name
- SIC-EEG-NF (NCT07815457)
- Testing
- Contingent Subject-Independent Classifier-Based EEG Neurofeedback
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Spinal Cord Injury Cervical, Tetraplegia/Tetraparesis
Implantable Wireless Brain-Computer Interface Systems in Patients With Tetraplegia
Objectives of Study: This trial aims to evaluate the safety and efficacy of an implantable wireless brain-computer interface system in patients with tetraplegia resulting from spinal cord injury.
- Conditions
- Spinal Cord Injury Cervical, Tetraplegia/Tetraparesis, Spinal Cord Injuries (SCI)
- Trial name
- LEAP (NCT07784088)
- Testing
- IWBCIS
- Where
- China
- Volunteers
- 34 people
- Sponsor
- BCIFlex Medical Technology Co., Ltd.
Healthy, Tetraplegia
Stable and Independent Communication Brain-computer Interfaces
People with locked-in syndrome cannot move their limbs or talk because of a motor impairment, but remain conscious and intellectually awake.
- Conditions
- Healthy, Tetraplegia, Locked-in Syndrome
- Trial name
- NCT03213561
- Testing
- Stable and Independent Brain-computer Interfaces for Communication
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tomislav Milekovic
Stroke, Neurorehabilitation
Motor Imagery and Motor Execution Based BCI in Stroke
About 50% of stroke patients are unable to live independently because of residual disability. Brain-computer interface (BCI) is based on closed-loop theory, which facilitates neurological remodeling by establishing a bridge…
- Conditions
- Stroke, Neurorehabilitation, Motor Imagery, Motor Execution
- Trial name
- BCI-MIME (NCT05634616)
- Testing
- Motor imagery and motor execution based BCI
- Where
- China
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Acute Ichemic Stroke
Study on the Efficacy and Safety of Non-Invasive Brain-Computer Interface With MRI-Guided Multi-Channel Time-Domain Interference Stimulation in Treating Motor Dysfunction in Acute Cerebral Infarction Patients
This trial enrolls patients with acute ischemic stroke. The key inclusion criteria are: patient age 18-80 years, within 72 hours of symptom onset, National Institutes of Health Stroke Scale (NIHSS) score of 4-24, motor…
- Trial name
- NCT07912450
- Testing
- Transcranial Temporal Interference Stimulation (tTIS)
- Where
- China
- Volunteers
- 378 people
- Sponsor
- The First Affiliated Hospital of Bengbu Medical University
Glaucoma, Macular Degeneration
BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases
The purpose of this research study is to better understand the impact of visual impairment caused by different eye diseases on the ability to perform daily activities and compare it to that in patients without eye diseases.
- Conditions
- Glaucoma, Macular Degeneration, Glaucoma Suspect, Optic Neuropathy
- Trial name
- NCT03318549
- Testing
- Visual Performance tests, Brain-computer interface
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Miami
Stroke
fNIRS-BCI Neurofeedback in Stroke Rehabilitation
Objectives: 1) To compare the effects of closed-loop brain-computer interface (BCI) driven observational imitation training versus sham BCI open-loop observational imitation training on improving upper limb motor functions in…
- Trial name
- NCT06503484
- Testing
- Brain-computer interface
- Where
- Hong Kong
- Volunteers
- 44 people
- Sponsor
- The Hong Kong Polytechnic University
Traumatic Brain Injury
Testing Devices That Involve the Sense of Touch in Subjects With Traumatic Brain Injury
Background: Previous studies have shown that computer-based devices that simulate everyday tasks can be helpful for evaluation and rehabilitation in people who have had strokes.
- Trial name
- NCT01404494
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS)
Control of Assistive Devices Via Brain-Computer Interface Technology
The CONVOY Study is a clinical trial designed to explore the feasibility of participants from the PRIME Study (NCT06429735) using the N1 Implant to control various assistive devices.
- Conditions
- Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS), Quadriplegia, Spinal Cord Injury (SCI)
- Trial name
- CONVOY (NCT06710626)
- Testing
- Assistive Robotic Arm
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Neuralink Corp
Healthy Volunteers
Sensorimotor Based Brain Computer Interface
Sensorimotor (also know as mu) rhythm based brain-computer interfaces (BCIs) are a tool for controlling electronic devices using only brain signals.
- Trial name
- NCT02169375
- Testing
- Brain computer Interface Mu (SMR) rhythm
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cerebral Palsy, Pediatric Stroke
BCI@Home: Brain Computer Interface Solutions to Enable Youth Living With Severe Disabilities
The goal of this trial is to evaluate use of brain computer interfaces (BCI) at home for children with severe severe physical disabilities. The main questions it aims to answer are: 1.
- Conditions
- Cerebral Palsy, Pediatric Stroke, Genetic Condition, Acquired Brain Injury (Including Stroke)
- Trial name
- BCI@home (NCT07073378)
- Testing
- Brain computer interface
- Where
- 2 sites in Canada
- Volunteers
- 18 people
- Sponsor
- University of Calgary
Stroke
Lifescapes System in Post-stroke Hand Recovery
Stroke is a leading cause of long-term disability, with 30-60% of survivors remaining unable to use their affected arms after discharge.
- Trial name
- NCT07784920
- Testing
- Lifescapes
- Where
- 2 sites in Singapore
- Volunteers
- 32 people
- Sponsor
- National University Hospital, Singapore
Stroke
REINVENT: A Brain and Muscle Computer Interface for Stroke
Stroke is a leading cause of adult disability in the United States. High doses of repeated task-specific practice have shown promising results in restoring upper limb function in chronic stroke (>6 months after onset).
- Trial name
- REINVENT (NCT06285175)
- Testing
- Tele-REINVENT
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California
Generalised Anxiety Disorder
A Neuro-Technological Intervention for Adolescents With GAD
This study aims to evaluate the safety and acceptability of a basic neuro-technological intervention in the treatment of adolescents with Generalised Anxiety Disorder (GAD).
- Trial name
- NCT03813290
- Testing
- Neuro-technological Intervention
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- National Healthcare Group, Singapore
Stroke
A Closed-loop Brain-computer Interface for Stroke
It may be hard to acquire stable sensorimotor rhythm from the affected motor cortex for patient without a response of paretic hand.
- Trial name
- NCT04465786
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan