Clinical trials: Breast Cancer, Female
Breast Cancer
Letrozole in Preventing Breast Cancer in Postmenopausal Women
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. Letrozole may be effective in preventing the development or recurrence of breast cancer in postmenopausal…
- Trial name
- WISE (NCT00090857)
- Testing
- Letrozole
- Where
- 5 sites in United States
- Volunteers
- 49 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Neoplasms, Premature Birth
Evaluating Patient Information Prescriptions
Research shows that patient satisfaction with medical care correlates strongly with how satisfied they are with the ease of getting information from their providers regarding their medical condition.
- Trial name
- NCT00355381
- Testing
- Information Services (IRx)
- Where
- United States
- Volunteers
- 299 people
- Sponsor
- Johns Hopkins University
Breast Cancer Females
Physical Exercise on Metabolic Health, Gut Microbiota, Physical Fitness, and Quality of Life in Obese Breast Cancer Survivors
The goal of this clinical trial is to evaluate whether a 3-month dance-based exercise program combined with individualized nutrition can improve health outcomes in obese breast cancer survivors in remission.
- Trial name
- OBINT (NCT07213271)
- Testing
- Dance classes
- Where
- Slovakia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Comenius University
Brain Cancer, Breast Cancer
Study of Health Effects of Cosmetic Breast Augmentation
This study will examine long-term health effects of cosmetic breast augmentation (enlargement) with silicone gel breast implants.
- Conditions
- Brain Cancer, Breast Cancer, Lung Cancer, Suicide
- Trial name
- NCT00342953
- Where
- United States
- Volunteers
- 17,424 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer, Neoplasm Metastasis
GCC 0845:Vorinostat and Lapatinib in Advanced Solid Tumors and Advanced Breast Cancer to Evaluate Response and Biomarkers
This research is being done to find out how safe and how well the combination of lapatinib and vorinostat works against advanced cancers.
- Trial name
- NCT01118975
- Testing
- Vorinostat, Lapatinib
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Maryland, Baltimore
Neoplasms, Breast
Tykerb Evaluation After Chemotherapy (TEACH): Lapatinib Versus Placebo In Women With Early-Stage Breast Cancer
This study was designed to evaluate and compare the safety and efficacy of an oral dual tyrosine kinase inhibitor, lapatinib, versus placebo in women with early-stage ErbB2-overexpressing breast cancer who have completed their…
- Trial name
- NCT00374322
- Testing
- lapatinib
- Where
- 439 sites in United States, Argentina and 31 more
- Volunteers
- 3,166 people
- Sponsor
- GlaxoSmithKline
Breast Cancer, Head and Neck Cancer
Docetaxel in Treating Patients With Solid Tumors and Abnormal Liver Function
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of docetaxel in treating patients with advanced solid…
- Conditions
- Breast Cancer, Head and Neck Cancer, Lung Cancer, Ovarian Cancer
- Trial name
- NCT00002901
- Testing
- docetaxel
- Where
- 3 sites in United States
- Sponsor
- City of Hope Medical Center
Pleural Effusion, Malignant, Ascites, Malignant
Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
The primary objective of this study, sponsored by Travera Inc. in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations…
- Conditions
- Pleural Effusion, Malignant, Ascites, Malignant, Carcinoma, Carcinoma, Hepatocellular
- Trial name
- TraveraRTGx (NCT05461430)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Travera Inc
Advanced Solid Tumors
Study of Continuous OSI-906 Dosing
Multicenter, open-label, phase 1, cohort dose escalation study to determine the Maximum Tolerated Dose (MTD) on both Once Daily (QD) and Twice Daily (BID) schedules.
- Trial name
- NCT00514007
- Testing
- OSI-906
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 95 people
- Sponsor
- Astellas Pharma Inc
Breast Cancer Female
Factors Influencing Tamoxifen Adherence in Women With Breast Cancer Receiving Tamoxifen in Botswana.
Botswana is an ideal location to investigate tamoxifen adherence for numerous reasons. First, in contrast to many other countries in SSA, tamoxifen is affordable and widely available to women with ER+ breast cancer in Botswana.
- Trial name
- TAM (NCT06660030)
- Testing
- No intervention
- Where
- Botswana
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Breast Cancer
Exemestane or Docetaxel-Cytoxan in Low Recurrence Score Cancers
The patients are being asked to take part in this study because they have a hormone receptor-positive breast cancer (contains estrogen and/or progesterone receptors) and their doctor has told them that they have an option to…
- Trial name
- NCT00941330
- Testing
- Exemestane, Docetaxel, Cytoxan
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- Emory University
Breast Cancer
Genetic Study of CYP2D6 Enzyme and Therapeutic Drug Monitoring of Tamoxifen
Aim of work: 1. To estimate the frequency of Cyp2D6*1 and *4 alleles in Egyptian patients maintained on tamoxifen (20 mg/day) for management of ER +ve breast cancer. 2.
- Trial name
- NCT03582865
- Testing
- Tamoxifen 20 mg
- Volunteers
- 100 people
- Sponsor
- Assiut University
Breast Cancer, Cervical Cancer
Muslim Americans Reaching for Health and Building Alliances (MARHABA): Patient Navigation Intervention to Increase Breast and Cervical Cancer Screening Among Muslim Women in New York City
Studies have reported Muslims in the US and NYC face numerous language and healthcare access barriers. This is a randomized randomized controlled design will be used to test the efficacy of a Patient Navigation (PN) intervention…
- Trial name
- MARHABA (NCT03081507)
- Testing
- SM-LHW, PN-LHW
- Where
- United States
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Breast Cancer, Osteoporosis
Bone Mineral Density in Postmenopausal Women With Primary Breast Cancer Who Are Receiving Treatment on Clinical Trial
RATIONALE: Learning about the effect of exemestane and anastrozole on bone mineral density in postmenopausal women with primary breast cancer may help plan treatment, decrease the risk of broken bones, and help patients live more…
- Trial name
- NCT00354302
- Testing
- calcium carbonate, calcium citrate, cholecalciferol
- Where
- 13 sites in Canada
- Volunteers
- 497 people
- Sponsor
- NCIC Clinical Trials Group
Breast Cancer
Combination Chemotherapy and Trastuzumab in Treating Women With Metastatic Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003612
- Testing
- trastuzumab, carboplatin, paclitaxel
- Where
- 25 sites in United States, Canada
- Volunteers
- 92 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Cancer
Exercise Information for Women With Cancer
Fatigue is a troublesome symptom for breast cancer patients, which might be mitigated with exercise. Cancer patients often prefer their oncologist recommend an exercise program, yet a recommendation alone may not be enough to…
- Trial name
- NCT03120819
- Testing
- Oncologist Recommendation, Oncologist Recommendation + DVD
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Oregon Health and Science University
Breast Cancer
ATAC - Arimidex, Tamoxifen Alone or in Combination
The aim of this study is to test whether Arimidex alone or in combination with Tamoxifen is beneficial in the treatment of breast cancer.
- Trial name
- NCT00849030
- Testing
- Anastozole (Arimidex), Tamoxifen (Nolvadex)
- Volunteers
- 9,358 people
- Sponsor
- AstraZeneca
Improve Sexual Health, Improve Vulvovaginal Health
A Study to Prevent and Improve Sexual Health Concerns for People With Breast Cancer
Researchers are doing this study to look at whether sexual health counselling and using non-hormonal moisturizer at the start of ovarian suppression may be able to prevent or reduce side effects such as vaginal dryness and sexual…
- Trial name
- NCT05910294
- Testing
- questionnaires, moisturizers
- Where
- 7 sites in United States
- Volunteers
- 50 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
A Study of Bevacizumab (Avastin) in Women With HER2 Negative Metastatic Breast Cancer
This study will evaluate the efficacy and safety of 2 doses of Avastin in combination with docetaxel, versus docetaxel plus placebo, in patients with metastatic HER2 negative breast cancer who are candidates for taxane-based…
- Trial name
- NCT00333775
- Testing
- Docetaxel, Bevacizumab
- Where
- 114 sites in Australia, Austria and 22 more
- Volunteers
- 736 people
- Sponsor
- Hoffmann-La Roche
Breast Neoplasm Female, Radiotherapy Side Effect
Gated Radiotherapy in Left Sided Breast Cancer Patients
To assess the need of respiratory gated radiotherapy in left sided breast cancer patients.
- Conditions
- Breast Neoplasm Female, Radiotherapy Side Effect, Heart Diseases
- Trial name
- GATTUM (NCT03534570)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Technical University of Munich
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