Clinical trials: Breast Cancer Related Lymphedema
Lymphedema, Secondary Lymphedema
Efficacy of Complete Decongestive Therapy for Limb Lymphedema: Response Profile and Predictive Modeling
Background: Complete decongestive therapy (CDT) is the standard treatment for lymphedema, but response varies by localization and laterality.
- Conditions
- Lymphedema, Secondary Lymphedema, Breast Cancer-Related Lymphedema, Upper Extremity Lymphedema
- Trial name
- LYMPH-PROG (NCT07878598)
- Testing
- Intensive phase of Complete Decongestive Therapy
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Ryazan State Medical University
Lymphedema, Breast Cancer, Mastectomy Related Lymphedema
Complete Decongestive Therapy Versus Non-pneumatic Compression Therapy in Post Mastectomy Lymphedema
The aim of the study is to compare the effectiveness of Complete Decongestive Therapy and Non-Pneumatic Compression Therapy, both combined with routine physical therapy, in reducing pain and edema volume, improving range of…
- Conditions
- Lymphedema, Breast Cancer, Mastectomy Related Lymphedema, Post Mastectomy Lymphedema
- Trial name
- CDT (NCT07217288)
- Testing
- Non Pneumatic compression device, Complete Decongestive therapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Breast Cancer Related Lymphedema
EFFECT OF ESWT ON BREAST-CANCER RELATED LYMPHEDEMA
The aim of this study is to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) combined with complete decongestive therapy (CDT) compared with CDT alone in patients with breast cancer-related lymphedema.
- Trial name
- NCT07854262
- Testing
- Complete Decongestive Therapy, Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ankara City Hospital Bilkent
Breast Cancer-Related Lymphedema, Lymphedema
Effectiveness of a Tele-Rehabilitation-Based Exercise and Self-Lymphatic Drainage Program Supported by Self-Management for Breast Cancer-Related Lymphedema
A total of 64 women, aged between 20 and 65 years, diagnosed with stage I or II breast cancer-related lymphedema and not meeting the exclusion criteria, who registered at the outpatient clinics of the Department of Physical…
- Trial name
- NCT07794904
- Testing
- Tele-rehabilitation-Based Exercise and Self-Lymphatic Drainage Program, Home-Based Exercise and Self-Lymphatic Drainage Program
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University
Breast Cancer, Breast Cancer Treatment Related Lymphedema
Early Intervention
This research study is a Pilot Study examining the use of a compression sleeve with embedded sensor to prevent lymphedema.
- Trial name
- NCT05326165
- Testing
- Juzo Compression Sleeve and Glove, Compression Sleeve Sensor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer Related Lymphedema
Manual Lymphatic Drainage With Diaphragmatic Breathing Exercises in Post Radical Mastectomy
Lymphedema is a persistent and chronic swelling condition that commonly develops after breast cancer surgeries involving axillary lymph node dissection (ALND).
- Trial name
- NCT07676045
- Testing
- Manual Lymphatic Drainage, Diaphragmatic Breathing Exercises
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- University of Lahore
Breast Cancer Related Lymphedema
Effects of Core-Focused Exercise Training and Kinesiology Taping in Women With Breast Cancer-Related Lymphedema
The aim of the present study is to investigate the effects of trunk- focused exercise training and kinesiology taping, in addition to standard lymphedema treatment (complex decongestive therapy-CDT) on posture, pain…
- Trial name
- NCT07673939
- Testing
- Complex Decongestive Therapy, Trunk Focused exercises, Kinesiology taping
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hacettepe University
Breast Cancer-Related Lymphedema, Autonomic Dysfunction
Evaluation of Sympathetic Skin Response and Its Relationship With Clinical Response to Complex Decongestive Therapy in Patients With Postmastectomy Lymphedema
This prospective observational single-center study aimed to evaluate sympathetic skin response (SSR) in patients with postmastectomy upper extremity lymphedema and to investigate the relationship between SSR parameters and…
- Conditions
- Breast Cancer-Related Lymphedema, Autonomic Dysfunction, Postmastectomy Lymphedema
- Trial name
- BCRL-SSR (NCT07585253)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Breast Cancer Related Lymphedema
Investigation of the Effects of Complex Decongestive Physiotherapy on Sleep Quality and Quality of Life in Women With Breast Cancer Related Lymphedema
Breast cancer is the most common type of cancer among women globally and has the highest mortality rate. Surgical interventions are typically required in the treatment of breast cancer, but these procedures can lead to…
- Trial name
- NCT06697158
- Testing
- Physiotherapy and rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Abant Izzet Baysal University
Breast Cancer-Related Lymphedema, BCRL
Comparison of IPC Therapy as an Alternative or an Adjunct to MLD Within CDT for BCRL
Breast cancer is the most common cancer among women worldwide and lymphedema is one of its most significant complications. Breast cancer-related lymphedema (BCRL) may develop shortly after treatment or even years later, causing…
- Trial name
- NCT07154043
- Testing
- Complete Decongestive Therapy (CDT), CDT + Intermittent Pneumatic Compression (IPC), CDT without Manual Lymph Drainage plus Intermittent Pneumatic Compression
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Pamukkale University
Breast Cancer Related Lymphedema
Gait Characteristics of Women With Breast Cancer-Related Lymphedema
Upper extremity lymphedema is one of the most common problems associated with cancer treatments in breast cancer survivors. Lymphedema causes asymmetry, changes posture, decreases arm swing due to increased weight, and as a…
- Trial name
- NCT07011277
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Breast Cancer-Related Lymphedema, Breast Cancer
Pedicled Lateral Chest Wall Lymph-Adipofascial Flap to Prevent Arm Lymphedema After Breast Cancer Surgery
Breast cancer surgery that includes removal of lymph nodes from the armpit (axillary lymph node dissection) can disrupt normal lymphatic drainage and may lead to arm swelling, known as lymphedema.
- Conditions
- Breast Cancer-Related Lymphedema, Breast Cancer, Postoperative Complications
- Trial name
- LAF-ALND (NCT07415200)
- Testing
- Pedicled Lateral Chest Wall Lymph-Adipofascial Flap Axillary Reconstruction
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Breast Cancer Related Lymphedema
Clinical Feasibility of Mobile App-Based Self-Management for Breast Cancer-Related Lymphedema
The study evaluates a newly developed service that provides personalized self-management guidance based on evidence-based arm circumference measurements and resulting volume changes.
- Trial name
- NCT06922513
- Testing
- digital health (Application and Smart Measuring Tape)
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Samsung Medical Center
Breast Cancer-Related Lymphedema
Combined Exercise Effects in Breast Cancer-related Lymphedema
Breast cancer-related lymphedema (BCRL) is a common and debilitating condition that affects quality of life, mobility, and well-being.
- Trial name
- LymFit (NCT07365618)
- Testing
- Exercise, Educational Sessions
- Where
- Portugal
- Volunteers
- 58 people
- Sponsor
- Faculdade de Motricidade Humana
Breast Cancer Related Lymphedema, Covid19
Patient Experiences With the COVID-19 Vaccination After Breast Cancer Treatment
This study aims to elicit patient experiences, choices, and side effects associated with the COVID-19 vaccine after breast cancer surgery.
- Trial name
- LymphVAX (NCT04872738)
- Testing
- Survey
- Where
- United States
- Volunteers
- 714 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer-Related Arm Lymphedema, Quality of Life Impairment
Prehabilitation of Breast Cancer-Related Lymphedema
This prospective prehabilitation study aims to evaluate the effects of an individualized exercise program initiated before breast cancer surgery and continued for 12 months postoperatively.
- Conditions
- Breast Cancer-Related Arm Lymphedema, Quality of Life Impairment, Fatigue Syndrome, Chronic, Prehabilitation
- Trial name
- NCT07301580
- Testing
- Prehabilitation Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Breast Cancer-related Subclinical Lymphedema
Subclinical Lymphedema Treatment Study
Primary Objective To compare the effectiveness of 2 treatment protocols for patients with breast cancer-related subclinical lymphedema identified through bioimpedance spectroscopy, L-dex scores Secondary Objectives To determine…
- Trial name
- SLT (NCT03292198)
- Testing
- 20-30 mmHg compression sleeve and gauntlet, Manual Lymphatic Drainage
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Mercy Research
Breast Cancer-Related Lymphedema, Breast Carcinoma
Indocyanine Green Fluoroscopy and SPY Angiography for the Assessment of Lymphatic Structure in Breast Cancer Patients at Risk for Breast Cancer-Related Lymphedema
This clinical trial assesses the change in lymphatic structure from placement of an intravenous (IV) line and fluid administration using a diagnostic agent, indocyanine green (ICG), with SPY (Trademark) angiography in breast…
- Trial name
- NCT06672224
- Testing
- Fluid Therapy, Indocyanine Green, Questionnaire Administration
- Sponsor
- City of Hope Medical Center
Breast Cancer Related Lymphedema
Factors Associated With Health-related Quality of Life in Patients With Breast Cancer-Related Lymphedema Undergoing Prospective Surveillance
Breast cancer-related lymphedema (BCRL) is a chronic condition that affects more than 1 in 5 breast cancer survivors. It causes swelling, pain, and reduced arm function, which can significantly impact quality of life.
- Trial name
- NCT07165275
- Where
- South Korea
- Volunteers
- 203 people
- Sponsor
- Samsung Medical Center
Breast Edema, Breast Cancer Related Lymphoedema
Effectiveness of Kinesio Taping in Patients With Chronic Breast and/or Truncal Oedema After Treatment for Breast Cancer.
The goal of the KiTaLymph trial is to investigate whether the application of kinesio tape is effective in women with persistent (>6 months) breast and/or truncal oedema after treatment for breast cancer.
- Conditions
- Breast Edema, Breast Cancer Related Lymphoedema, Breast Cancer Related Lymphedema, Truncal Lymphedema
- Trial name
- KiTaLymph (NCT07080476)
- Testing
- Decongestive lymphatic therapy, Kinesio tape, Compression bra (sub-study)
- Where
- 4 sites in Belgium
- Volunteers
- 128 people
- Sponsor
- Universiteit Antwerpen