Clinical trials: Breast Cancer Risk
Breast Cancer
Changes in Breast Cancer Biomarkers Using Synergistic Prostaglandin Inhibitors
This is a biomarker study with the goal of measuring changes in proteins and gene methylation. This study is not intended for use in diagnosing, mitigating, treating, curing, or preventing disease.
- Trial name
- NCT01425476
- Testing
- Celecoxib, Cholecalciferol
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Breast Cancer
Breast Study to Determine the Ability of Non-Invasive Optical Transillumination Spectroscopy to Predict Breast Density.
The purpose of this study is to learn more about the application of transillumination measurements in the determination of breast cancer risk.
- Trial name
- NCT00188682
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Invasive Breast Cancer
Identification of Novel Genetic Factors That Contribute to Risk for Breast Cancer
The purpose of this study is to identify novel genetic factors which distinguish breast cancer in younger women compared to older women.
- Trial name
- NCT00276120
- Where
- United States
- Volunteers
- 4,385 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer Screening, Colon Cancer Screening
Bundled Cancer Screening and Genetic Services Navigation
The goal of this study is to test bundled familial cancer risk assessment + multicancer (colorectal + breast) vs. single (breast) cancer navigation, using a wait list control for colorectal cancer screening referral and…
- Conditions
- Breast Cancer Screening, Colon Cancer Screening, Genetics Predisposition
- Trial name
- NCT07228000
- Testing
- Breast cancer screening navigation, Multicancer screening navigation, Usual care genetics referral
- Where
- 2 sites in United States
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Breast Cancer, Nurse
Examination of the Effect of Counselling and Follow-up After Breast Cancer Awareness Education
The aim of the study was to examine the effect of counselling and follow-up after education on the risks and prevention methods of breast cancer on early diagnosis behaviours and healthy lifestyle behaviours.
- Conditions
- Breast Cancer, Nurse, Education, Counselling
- Trial name
- NCT06005025
- Testing
- Reminder message
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Inherited Cancer Syndrome, Prostate Cancer
Improving Care After Inherited Cancer Testing
The IMPACT Study seeks to refine and evaluate the effectiveness of interventions on improving guideline-adherent cancer risk management (CRM) and family communication (FC) of genetic test results for individuals with a documented…
- Conditions
- Inherited Cancer Syndrome, Prostate Cancer, Colorectal Cancer, Endometrial Cancer
- Trial name
- IMPACT (NCT04763915)
- Testing
- Correlative Studies (Survey), Correlative Studies (Interview), GeneSHARE
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Breast Cancer, Breast Neoplasms
A Study of Breast Cancer Risk Factors and Outcomes of People in Florida
The purpose of this study is to understand why different people have different risks and outcomes for breast cancer and non-breast cancer.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Diseases
- Trial name
- NCT06780176
- Testing
- Biospecimen Collection, Surgical Tissue Collection, Survey Collection
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Stockholm Mammography Risk Stratified Trial
SMART is a Phase III, randomised, non-blinded screening trial. Women who consent to participate in SMART are randomised to either individualised screening or screening according to the Swedish National Breast Cancer Screening…
- Trial name
- SMART (NCT06270355)
- Testing
- Risk based screening
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Breast Carcinoma, Breast Cancer
Exploring Cultural Acceptability of Community Breast Cancer Risk Assessment Among Hispanic Women in Maricopa County
This study explores the cultural acceptability of community breast cancer risk assessment among Hispanic women in Maricopa county.
- Conditions
- Breast Carcinoma, Breast Cancer, Breast Cancer Female
- Trial name
- NCT06112795
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Cancer
Studying Biomarkers in Nipple Fluid, Urine, and Blood Samples From Women With Newly Diagnosed Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer and in Women at Risk of Developing Breast Cancer
RATIONALE: Studying samples of nipple fluid, urine, and blood in the laboratory from patients with cancer and from patients at risk of developing cancer may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT00897208
- Testing
- high performance liquid chromatography, laboratory biomarker analysis, mass spectrometry
- Where
- United States
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hereditary Cancer
Combined Breast Cancer Risk Study
A prospective, non-interventional study in women 18 to 84 years of age. Subjects will provide a sample for genetic testing and information about their medical and family history.
- Trial name
- NCT03067389
- Testing
- Diagnostic test
- Where
- 4 sites in United States
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- Myriad Genetic Laboratories, Inc.
Breast Cancer
A Data Collection Study for the Evaluation of a Novel Infra-red Breast Imaging System for Risk Assessment
Three-dimensional functional Metabolic Imaging (3D MIRA) is a new infrared imaging technology using the Real Imager 8 (RI8) developed by Real Imaging.
- Trial name
- NCT02505698
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Real Imaging Ltd.
Locally Advanced Breast Cancer, Breast Cancer
Using Bio Markers to Predict Disease Recurrence and Cognitive Function in High Risk Breast Ca
Women with breast cancer undergo treatments that decrease the chance of recurrence of cancer, but are associated with several side effects, including declines in memory and attention and other thinking abilities.
- Trial name
- Cyto-Cog (NCT00756132)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Breast Cancer
Dietary Fat, Eicosanoids and Breast Cancer Risk
The primary objective of this investigation is to determine whether diets designed to increase plasma n3 concentrations (a low fat diet, with or without n3 fatty acid enrichment), will favorably affect sex hormone distribution in…
- Trial name
- NCT01824498
- Testing
- Low Fat diet, Low Fat high n3 diet, High Fat Diet
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Breast Cancer
A Trial Assessing Feasibility of Allostatic Load Biomarkers and CVD Risk Among Black Breast Cancer Survivors
This study's overall objective is to test the effects of a culturally tailored gratitude, exercise, and mindfulness/emotional freedom techniques (GEM) psychosocial intervention on allostatic load and atherosclerotic…
- Trial name
- GEM (NCT06852560)
- Testing
- Gratitude, exercise, and mindfulness program
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Breast Cancer
Soy Protein and Breast Cancer Risk Reduction
Soy consumption has been associated with reduced risk for developing breast cancer. Ovarian hormones and breast density are considered breast cancer risk markers.
- Trial name
- NCT00204477
- Testing
- soy milk, cow's milk
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Breast Neoplasms, Breast Cancer
External Hypofractionated Radiotherapy With Simultaneous Integrated Boost in Early Breast Cancer Patients
This is a prospective non randomized phase two trial evaluating the feasibility of a ten fraction accelerated hypofractionated radiotherapy schedule with simultaneous integrated boost risk adapted in patients undergoing breast…
- Trial name
- ESIBIRE (NCT06224244)
- Testing
- Ten-fraction hypofractionated breast radiotherapy with 40 Gy simultaneous integrated bed boost, Ten-fraction hypofractionated breast radiotherapy with 43 Gy simultaneous integrated bed boost
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Breast Cancer
The Association Between Plasma Metabolites and the Risk, Efficacy and Prognosis in Early Breast Cancer
This study investigates plasma metabolites to clarify the relationship between these metabolites and breast cancer, aiming to identify valuable biomarkers.
- Trial name
- NCT06698679
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Breast Cancer Risk, Ovarian Cancer Risk
Population Based Germline Testing for Early Detection and Prevention of Cancer
PROTECT-C is a research study offering genetic testing to people to see whether they have a genetic change that increases their risk of breast, ovary, bowel, and/or womb cancer.
- Conditions
- Breast Cancer Risk, Ovarian Cancer Risk, Cancer Gene Mutation
- Trial name
- PROTECT-C (NCT07498829)
- Testing
- Genetic testing for Cancer Susceptibility Genes (CSGs) (BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, PALB2, MLH1, MSH2, MSH6) and personalised breast and ovarian cancer risk
- Where
- United Kingdom
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London