Clinical trials: Breast Reduction
Breast Neoplasm
Study of Anxiety After a Session of Energy Resonance by Cutaneous Stimulation
Performing a breast macrobiopsy can be extremely delicate and anxiety-provoking. It can have an impact on the course of future examinations. Patients' emotional feelings also have a definite impact on the nursing staff.
- Trial name
- MBRESC (NCT06056414)
- Testing
- Energy Resonance by Cutaneous Stimulation
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Centre Henri Becquerel
Hot Flashes, Breast Cancer
Solifenacin Compared to Clonidine for Reducing Hot Flashes Among Breast Cancer Patients
Hot flashes present a considerable problem for many breast cancer patients; these symptoms may be intensified by hormonal therapies, such as aromatase inhibitors or tamoxifen.
- Trial name
- NCT01530373
- Testing
- solifenacin, Clonidine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Arkansas
Macromastia
PEAK PlasmaBlade 4.0 in Bilateral Breast Reduction
The objective of this clinical study is to evaluate the operative performance of the PEAK PlasmaBlade 4.0 during bilateral breast reduction; to monitor and record post-operative pain, adverse events and skin scarring following…
- Trial name
- PRECISE (NCT00986453)
- Testing
- PEAK PlasmaBlade, Traditional Electrosurgery with scalpel
- Where
- 7 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medtronic Surgical Technologies
Breast Cancer
Mindfulness and Cancer Mamma - Clinical Trial MBSR Among Women Operated for Breast Cancer
The number of Danish women treated for breast cancer rise every year, though survival rates have improved, women can still expect to experience the diverse late effects reported by this group of patients.
- Trial name
- MICA (NCT00990977)
- Testing
- mindfulness based stress reduction (MBSR)
- Where
- Denmark
- Volunteers
- 336 people
- Sponsor
- Danish Cancer Society
Vaginal Atrophy, Breast Carcinoma
Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial
This phase III trial compares the effect of vaginal fractional CO2 laser therapy to placebo for the treatment of vaginal dryness in breast cancer survivors with symptoms of genitourinary syndrome of menopause (GSM).
- Trial name
- NCT05379153
- Testing
- Laser Therapy, Questionnaire Administration, Quality of Life Assessment
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Cicatrix
Intraoperative Hyaluronic Acid Gel Injection for Improvement of Scar Quality Following Reduction Mammaplasty
The purpose of this study is to determine the efficacy of hyaluronic acid gel injections compared to saline injections in improving scar quality in patients undergoing breast reduction surgery.
- Trial name
- NCT00958425
- Testing
- Hyaluronic acid gel, Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Breast Cancer, Lumpectomy
Efficacy and Safety of Fibrin Sealant Vapor Heated Solvent/Detergent Treated (FS VH S/D) for Reduction of Lymphatic Leakage by Sealing Axillary Lymph Node Dissection Sites
This study will monitor the safety of FS VH S/D and will evaluate whether FS VH S/D is superior to conventional surgical procedures in the reduction of lymphatic leakage by sealing the axillary lymphatics in subjects undergoing…
- Conditions
- Breast Cancer, Lumpectomy, Mastectomy Plus Axillary Lymph Node Dissection, Lymphatic Leakage
- Trial name
- NCT00161980
- Testing
- Fibrin Sealant VH S/D, Surgical intervention alone without Fibrin Sealant VH S/D application
- Where
- 8 sites in Austria, France and 2 more
- Sponsor
- Baxter Healthcare Corporation
Breast Cancer
Corticosteroids for Doxorubicin Liposome-Induced Hand-Foot-Skin Reactions
Investigating the Association Between Corticosteroid Use and Improvement in Doxorubicin Liposome-Induced Cutaneous Toxicity: Exploring the Feasibility and Mechanisms of Corticosteroids in Mitigating Liposomal Doxorubicin-Related…
- Trial name
- CHORD (NCT07362914)
- Testing
- Dexamethasone (12mg d1), Dexamethasone (2mg QD, d1-5,), Doxorubicin hydrochloride liposome injection
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Fudan University
Breast Cancer, Obesity
Breast Cancer Survivors RESET (Reducing Weight and Elevated Stress Levels Using Educational and Behavioral Tools): A Pilot, Feasibility Study
The overall object of this project is to test the feasibility and acceptability of an adapted stress management enhanced behavioral weight loss intervention for Black breast cancer survivors with obesity and elevated stress.
- Trial name
- RESET (NCT07101861)
- Testing
- Survivors RESET
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Pregnancy in Adolescence, Fear
Effect of MBSR Training on Childbirth Fear, Bonding and Breastfeeding in Adolescent Pregnant Women
This randomized controlled study aims to evaluate the effect of Mindfulness-Based Stress Reduction (MBSR) training given to adolescent pregnant women and their partners on fear of childbirth, maternal and paternal bonding, and…
- Conditions
- Pregnancy in Adolescence, Fear, Mother-Child Relations, Mindfulness
- Trial name
- NCT07540923
- Testing
- Mindfulness-Based Stress Reduction (MBSR) Training
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Inonu University
Breast Hypertrophy
ESPB Versus Intravenous Lidocaine for Pain After Mastopexy
Elective breast reduction surgery is associated with moderate-to-severe postoperative pain and a risk of developing chronic postsurgical pain.
- Trial name
- NCT07687069
- Testing
- Ultrasound - guided Erector Spine Plane Block (ESPB), Intraoperative intravenous lidocaine infusion
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Centre of Postgraduate Medical Education
Breast Cancer, Breast Neoplasms
Health Benefits of Expressive Writing Among Chinese Breast Cancer Survivors
This study is a randomized controlled trial (RCT) with the aim of determining the cultural sensitivity, feasibility, and effectiveness of an expressive writing intervention for Chinese breast cancer survivors.
- Trial name
- NCT02946619
- Testing
- Self-Regulation Condition, Enhanced self-Regulation Condition
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- University of Houston
Breast Cancer
Tesetaxel Plus Reduced Dose of Capecitabine vs. Capecitabine in HER2 Negative, HR Positive, LA/MBC
CONTESSA is a multinational, multicenter, randomized, Phase 3 study of tesetaxel in patients with HER2 negative, HR positive LA/MBC previously treated with a taxane in the neoadjuvant or adjuvant setting.
- Trial name
- CONTESSA (NCT03326674)
- Testing
- Tesetaxel and Capecitabine, Capecitabine
- Where
- 207 sites in United States, Australia and 17 more
- Volunteers
- 685 people
- Sponsor
- Odonate Therapeutics, Inc.
Post Operative Pain
The Efficacy of SPSIPB on Postoperative Pain in Patients Undergoing Reduction Mammoplasty Surgery: Case Series
The aim of this study is to investigate the postoperative analgesic efficacy of SPSIPB and its effect on opioid consumption in patients undergoing reduction mammoplasty.
- Trial name
- NCT05901116
- Testing
- Serratus posterior superior intercostal plane block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Cumhuriyet University
Breast Cancer
Reducing Arm Morbidity in Pre- and Post-breast Cancer Surgery
The overall aim of this pilot study is to explore the feasibility of a randomized trial to test the effectiveness of physical therapy, provided both pre- and post-surgery, on reducing arm morbidity and increasing health-related…
- Trial name
- NCT00170235
- Testing
- Prehabilitation, Usual care
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University
Breast, Posture
Physiotherapy After Breast Reduction Surgery
Background and Purpose: Breast reduction surgery is a major procedure that can lead to post-operative pain, postural deviations, and a temporary decline in quality of life.This clinical study aims to investigate the efficacy of…
- Conditions
- Breast, Posture, Mammaplasty, Sleep Quality
- Trial name
- NCT07729735
- Testing
- Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Rumeli University
Breast Reduction, Reduction Mammoplasty
Risk of Hematoma After Ketorolac Use in Reduction Mammoplasty.
The investigators hope to answer the question, "does ketorolac increase the risk of hematoma after reduction mammoplasty?" using a case-control study.
- Conditions
- Breast Reduction, Reduction Mammoplasty, Hematoma, Hemorrhage
- Trial name
- NCT03280043
- Testing
- Hematoma
- Where
- 2 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- McMaster University
Gynecomastia
Targeted Fat Reduction of Pseudogynecomastia in the Male Breast Using the ZELTIQ Coolsculpting System
Protocol is intended for the clinical evaluation of fat reduction in male breasts (pseudogynecomastia) using the ZELTIQ Coolsculpting System.
- Trial name
- NCT01791660
- Testing
- Zeltiq Coolsculpting System
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dermatology, Laser & Vein Specialists of the Carolinas
Breast Cancer
Mindfulness, Breast Cancer and Psycho-Immune Dysregulation
The purpose of this study is to evaluate the benefits of a Mindfulness Based Stress Reduction (MBSR) program for psycho-immune dysregulation in women newly diagnosed with breast cancer compared to women with breast cancer…
- Trial name
- NCT03652935
- Testing
- Mindfulness Based Stress Reduction, Health Education Series
- Volunteers
- 192 people
- Sponsor
- Loyola University
Breast Cancer
Genetic Risk Estimations for Influencing Decision Making in Women at High Risk of Breast Cancer, GENRE 2 Study
The primary aim of this study is to determine if the addition of an individual polygenic risk score (PRS) in addition to the Breast Cancer Risk Assessment Tool (BCRAT) or Tyrer-Cuzick (IBIS) score will aid women at risk of breast…
- Trial name
- GENRE2 (NCT04474834)
- Testing
- Polygenic Risk Score
- Where
- 5 sites in United States
- Volunteers
- 737 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic