Clinical trials: Breast Reduction
Macromastia (Symptomatic)
Use of the PEAK PlasmaBlade 4.0 in Bilateral Breast Reduction
The objective of this clinical study is to evaluate the operative performance of the PEAK PlasmaBlade® 4.0 during bilateral breast reduction; to monitor and record post-operative pain, adverse events and skin scarring following…
- Trial name
- NCT01404351
- Testing
- PEAK PlasmaBlade, Scalpel and Traditional Electrosurgery
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medtronic Surgical Technologies
Women With Breast Implants With and Without Self-reported Systemic Symptoms, Women Undergoing an Elective Mastopexy (Breast Lift) or Small Reduction
Systemic Symptoms: Biospecimen Analysis Study
An increasing number of women are reporting a collection of non-specific systemic symptoms thought to be caused by their breast implants.
- Trial name
- BII (NCT04255810)
- Testing
- Surgical collection of biospecimens
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Glicksman, Caroline, M.D.
Seroma Complicating A Procedure, Hematoma Postoperative
SEroma Reduction pOst MAstectomy "SEROMA Study"
This is a pilot study to evaluate the feasibility of conducting a larger trial to determine if the use of intraoperative topical tranexamic acid (TXA) decreases the rate of post-operative hematomas and seromas in breast cancer…
- Conditions
- Seroma Complicating A Procedure, Hematoma Postoperative, Breast Cancer
- Trial name
- SEROMA (NCT03738527)
- Testing
- Tranexamic Acid 100mg/mL, 20mL topical, Normal Saline Flush, 0.9%, 20mL topical
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Hamilton Health Sciences Corporation
Breast Cancer, Chemotherapy
A Pilot Study to Evaluate the Safety and Activities of EW02 in Reducing Neutropenia Caused by Chemotherapy
Study Hypothesis: EW02 is a polysaccharide-enriched crude extract from black soybean (BS). BS has been used extensively by the Chinese as food or traditional Chinese medicine for hundreds of years.
- Conditions
- Breast Cancer, Chemotherapy, Neutropenia
- Trial name
- NCT00555516
- Testing
- EW02
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Breast Cancer, Psychological Adjustment
Reducing Distress and Depressive-symptoms in Rural Women
Approximately 30% of U.S. breast cancer survivors experience significant cancer-related distress ranging from adjustment disorders, depression-symptoms and major depression up to 20 years after diagnosis.
- Trial name
- NCT03465813
- Testing
- CaringGuidance After Breast Cancer Diagnosis
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Nebraska
Hypogalactia
Effect of Acupuncture on Hypogalactia
The specific aims are (1) to assess the feasibility of a RCT studying acupuncture's impact on breast milk production, and (2) to compare the difference of milk production between acupuncture and power pumping.
- Trial name
- NCT03851718
- Testing
- Acupuncture Procedure, Power pumping
- Where
- United States
- Sponsor
- Texas Tech University Health Sciences Center
HIV Infections
Feasibility and Pilot Efficacy of Flash-heated Breast Milk to Reduce Maternal-to-Child-Transmission of HIV in Tanzania
This study will investigate the feasibility of HIV positive mothers in Tanzania to correctly use the Flash-heat method to pasteurize their breast milk and for how long they are able to do so.
- Trial name
- Flash-heat (NCT00523510)
- Testing
- Infant feeding counseling that includes Flash-heat
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy
This is a phase II, randomized, double-blinded, placebo-controlled trial designed to evaluate the efficacy of fezolinetant (45 mg a day) vs.
- Trial name
- NCT06917313
- Testing
- Fezolinetant
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Yale University
Breast Neoplasms
The Influence of Breast Cancer Risk and Risk Perception on Lifestyle Behaviors Among Women With a Family History: A Mixed Method Approach
Lifestyle behaviors among women with a family history of breast cancer are likely to be influenced by a number of factors, including both objective risk factors and subjective risk, or perceived risk.
- Trial name
- NCT00393406
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Weight Loss, Hypertrophy
Weight Loss Prior Mamma Reduction - A Pilot Study
Due to a higher risk of complications, obese and overweight patients with macromastia are in Denmark prohibited mammoplasty , as BMI must be within normal range, i.e. BMI < 25 kg/m2.
- Trial name
- MAMMARED (NCT02659371)
- Testing
- Low energy diet
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- Copenhagen University Hospital at Herlev
Breast Cancer
Evaluation of Mailers Promoting Mammogram Screening
In this evaluation, 3 different versions of mailers promoting annual mammograms are being sent to women on the month of their 50th and 64th birthdays.
- Trial name
- NCT04555902
- Testing
- Postcard, Small Gift, Loss Frame and Fear Appeals
- Where
- United States
- Volunteers
- 1,342 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Breast Cancer
Patient's Choice in the Reduction of Their Treatment in Women Over 65 Year With Breast Cancer
Standard treatment for women with early breast cancer (HR+, HER2-, T1N0) consists of the removal of the tumor from the breast by surgery with or without chemotherapy, followed by a whole-breast radiation therapy (usually one…
- Trial name
- CARTE (NCT05058196)
- Testing
- Whole breast radiotherapy, Intra Operative Radiotherapy
- Where
- France
- Volunteers
- 104 people
- Sponsor
- UNICANCER
Stress-related Problem, Breastfeeding
Effects of Different Relaxation Interventions on Reducing Stress in Chinese Breastfeeding Mothers
This pilot study aims to find the most effective relaxation technique to help primiparous mothers who are breastfeeding their infant.
- Conditions
- Stress-related Problem, Breastfeeding, Relaxation Therapy, Psychological Stress
- Trial name
- NCT03593551
- Testing
- five relaxation treatments and one control
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College, London
Breast Cancer
Health Benefits of HIT for Breast Cancer Patients
Treatment of cancer patients should not only involve removing the cancer, but should also focus on maintaining good health and well-being and quality of life.
- Trial name
- NCT03176888
- Testing
- Reduced-exertion, high-intensity interval training (REHIT), Cognitive behavioral therapy (CBT)
- Where
- United Kingdom
- Sponsor
- University of Stirling
Patients With Breast Cancer Requiring Mastectomy and Suitable for Reconstruction
Impact of ADM in Reduction of Surgical Complexity of Breast Reconstructions With Implants (Nava)
The objective of this study is to demonstrate that acellular dermal matrix, Strattice™ Reconstructive Tissue Matrix, can reduce the surgical complexity and post-operative pain of breast reconstructions with implants by avoiding…
- Trial name
- NCT01853436
- Testing
- Strattice™ Reconstructive Tissue Matrix
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- LifeCell
Breast Cancer, Hormone Receptor Positive / HER2-negative Breast Cancer
Short-Term Reduced Dietary Protein in ER+/HER2- Breast Cancer Patients During Neoadjuvant Chemotherapy
This study will examine if a short-term, reduced protein diet for the 3-day period prior to and on the day of each of the first 4 chemotherapy cycles and 4 days prior to primary breast surgery is well tolerated and adhered to by…
- Trial name
- NCT07897344
- Testing
- Dietary Protein Intervention
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Josephine Connolly-Schoonen
Postoperative Pain Breast Reduction, Mammaplasty
SPSIP Block for Pain Control After Breast Reduction Surgery
The goal of this clinical trial is to learn whether an ultrasound-guided serratus posterior superior intercostal plane block (SPSIP block) can lower the need for opioid pain medicine after breast reduction surgery.
- Conditions
- Postoperative Pain Breast Reduction, Mammaplasty, Analgesia, Nerve Block
- Trial name
- SPSIP-RM (NCT07657949)
- Testing
- Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block, Standard Perioperative Pain Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cumhuriyet University Hospital
Hematoma Postoperative, Venous Thromboembolism
Use of Tranexamic Acid in Reduction Mammoplasty
Breast reduction mammoplasty (BRM) is among the most commonly performed procedures in plastic surgery. However, postoperative hematoma is one of the most common complications following BRM.
- Trial name
- TREX-ARM (NCT04947514)
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Macromastia (Symptomatic)
Pectoral Block in Breast Reduction for Pain Control
A reduction mammoplasty is a commonly performed procedure for patients with symptomatic macromastia. The procedure involves removing breast parenchyma for an overall reduction in breast size and to alleviate patient symptoms…
- Trial name
- NCT07527039
- Testing
- Pectoral II Nerve Block, Post Operative Pain Relievers
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Carilion Clinic
Nausea and Vomiting Chemotherapy-Induced, Meditation Training
Meditation for Chemotherapy-Induced Nausea and Vomiting in Women With Breast Cancer
This randomized clinical trial aimed to evaluate the effectiveness of Twin Hearts Meditation in reducing chemotherapy-induced nausea and vomiting among women with breast cancer undergoing chemotherapy.
- Trial name
- Breast Cancer (NCT07470619)
- Testing
- Twin Heart Meditation
- Where
- Cyprus
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey