Clinical trials: Breath Holding
Breathing, Mouth
Impact of Diaphragmatic Breathing Coaching on Deep Inspiration Breath Hold Reproducibility and Organ Protection
To learn if coaching participants on diaphragmatic breathing will help participants to take larger, more reproducible breaths and feel less anxiety about their treatments.
- Trial name
- NCT06747533
- Testing
- CT simulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Glaucoma, Intraocular Pressure
Intraocular Pressure During Static Apnea
This prospective observational study evaluated changes in intraocular pressure (IOP) during dry static apnea (STA) in breath-hold divers.
- Conditions
- Glaucoma, Intraocular Pressure, Apnea
- Trial name
- NCT07604428
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Olomouc
Cancer
CPAP for Motion Management in Breast Radiotherapy; and Lung & Liver SABR
A phase II trial to determine the proportion of patients where the use of continuous positive airway pressure (CPAP) results in a superior radiation plan compared to standard planning procedures.
- Trial name
- CPAP-RT (NCT05396950)
- Testing
- CPAP
- Volunteers
- 70 people
- Sponsor
- Waikato Hospital
Exercise Training, Apnea
Breathing Protocol in Breath-hold Divers
The aim of this randomized controlled trial study was to assess the effects of an 4-week exercise program on the recovery capacity after a voluntary maximal apnea.
- Conditions
- Exercise Training, Apnea, Breathholding, Breathing Exercises
- Trial name
- NCT04366414
- Testing
- hook breathing removing nose-clip, usual breathing (UB)
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Essential Tremor, Dystonic Tremor
VIM DBS Respiratory Modulation: N-of-1 Trial
Research from our group has demonstrated modulation of PEFR in patients with STN and PAG stimulation. However, the effect of VIM (motor thalamus) stimulation remains to be investigated.
- Trial name
- NCT05381688
- Testing
- VIM DBS
- Sponsor
- University of Oxford
Breast Cancer
Large Segmentation Radiotherapy ± Deep Inspiration Breath Hold(DIBH) for Left Breast Cancer
The study is a single-center, prospective, non-randomized controlled study. The primary objective is to examine the clinical outcomes of utilizing Deep Inspiration Breath Hold (DIBH) in conjunction with hypo-fractionated…
- Trial name
- DLLEB (NCT06660628)
- Testing
- Large Segmentation Radiotherapy, DIBH, Surface guided radiation therapy
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Peking Union Medical College Hospital
Coronary Artery Disease
Breath-hold Cardiac Hybrid SPECT/CCTA
This study aims at combining inspiration breath-hold myocardial perfusion SPECT with coronary CT angiography.
- Trial name
- NCT02469051
- Testing
- Breathhold SPECT-MPI, Standard freebreathing SPECT-MPI, Coronary CT angiography
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Non-Small-Cell-Lung Cancer (NSCLC)
Prognostic Value of Tumor Hypoxia, as Measured by 18F-FMISO Breath Hold PET/CT, in Non-Small-Cell-Lung Cancer (NSCLC) Patients
The purpose of this study is to help researchers investigate if a new imaging agent named 18F-FMISO can predict if patients with lung cancer will respond to standard therapy, as well as whether disease will reoccur in the future.
- Trial name
- NCT02016872
- Testing
- 18F-FMISO, PET/CT
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pancreas Cancer
Breath-Hold Technique for Pancreatic Stereotactic Body Radiation Therapy (SBRT) Patients
The Investigator proposes the development of an extended reality (xR) training platform for patients undergoing radiation treatment for pancreatic cancer.
- Trial name
- NCT04843306
- Testing
- Biofeedback, Active Breathing Control Technique
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Lung Cancer
Pilot Study of SGRT Alone vs. SGRT With Fiducials for Breath Hold SBRT tx of the Lung
This is a pilot study designed to to provide data and experience comparing two different techniques of breath hold SBRT treatments. The first technique will include SGRT, but with the assistance of implanted fiducials.
- Trial name
- NCT04060927
- Testing
- SGRT
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Wake Forest University Health Sciences
Liver Fibrosis
Rapid Breath-hold Quantitative Macromolecular Proton Fraction Imaging for Liver Fibrosis
Chronic liver disease is a major health problem worldwide. Liver fibrosis is a key feature in most chronic liver diseases. When identified early, liver fibrosis may be reversible.
- Trial name
- NCT04429100
- Testing
- Magnetic Resonance Imaging
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Left-Sided Breast Cancer
Assessment of Left-sided Cardiac Sparing Through the Use of 3-dimensional Surface Matching-based Deep Inspiration Breath Hold and Active Breathing Control
The standard treatment for breast cancer is surgery followed by adjuvant breast radiation therapy in most cases. For left sided breast cancers, the heart dose delivered by the radiation treatment is often of particular concern.
- Trial name
- NCT03459898
- Testing
- AlignRT system (VisionRT Ltd., London, UK)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Sunnybrook Health Sciences Centre
Small Cell Lung Cancer, Non Small Cell Lung Cancer
A Prospective Study of Variation in Breath Holding Times at Various Phases of Respiration During the Course of Radiotherapy Including the Effect of Respiratory Training in Lung Cancer Patients
100 suitable patients of lung cancer shall be taken into the study over a period of 2 years. As per the existing treatment protocol in our department, all patients suitable shall undergo a routine Pulmonary function testing…
- Trial name
- NCT01429766
- Testing
- Respiratory Training
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Tata Memorial Hospital
MRI, MRI Image Enhancement
Optimizing Liver MRI Using Breath-Holding With and Without Oxygen
The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy…
- Trial name
- NCT07135401
- Testing
- Breath-hold conditions
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Esophageal Cancer
BReath Hold TecHniquEs for Radiotherapy of Esophageal Carcinoma
The main objective of the first part of the study is to determine the most optimal method for DIBH (active breathing control vs voluntary coached) and its reproducibility.
- Trial name
- BROTHER (NCT06317272)
- Testing
- DIBH using ABC technique, DIBH using VC technique
- Where
- Netherlands
- Volunteers
- 1 people
- Sponsor
- University Medical Center Groningen
Exercise Training, Respiratory Muscle Training
Effects of High Intensity Interval Training (HIIT) vs. Inspiratory Muscle Training on the Recovery After a Maximal Apnea.
The aim of this randomized cross-over controlled study was to assess the effects of an 4-week exercise program on the recovery capacity after a voluntary maximal apnea.
- Conditions
- Exercise Training, Respiratory Muscle Training, High-Intensity Interval Training, Apnea
- Trial name
- (HIIT) (NCT04084535)
- Testing
- High intensity interval training, Inspiratory muscle training
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
HCC - Hepatocellular Carcinoma, Liver Metastases
Part of the Modern Art Study
One of the possible treatments for patients with liver tumours (hepatocellular carcinoma (HCC) or liver metastases) at the Erasmus MC is stereotactic body radiation therapy (SBRT) on the Cyberknife.
- Trial name
- NCT06768242
- Testing
- Cone beam CT
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Erasmus Medical Center
Lung Tumor Resuction
Effects of Buteyko Breathing Technique Versus Incentive Spirometer on Breath Holding Time, Cardiopulmonary Endurance and Quality of Life in Patients With Post Lung Tumor Resection
The pulmonary complications are the major cause of morbidity and mortality following Lung surgeries. The Buteyko breathing technique is used for reversing the health condition such as poor breathing, mouth breathing and over…
- Trial name
- NCT05118347
- Testing
- Buteyko Breathing Technique
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Shahbaz Ahmad
Lung Cancer
CT in Diagnosing Patients With Lung Cancer
This clinical trial studies computed tomography (CT) in diagnosing patients with lung cancer. Diagnostic procedures, such as CT, may help find and diagnose lung cancer.
- Trial name
- NCT01888510
- Testing
- computed tomography, 4-dimensional computed tomography, cone-beam computed tomography
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Commonwealth University
Breast Cancer
The Impact of Respiratory Training of DIBH Radiotherapy for Breast Cancer
Breast cancer DIBH (Deep Inspiration Breath Hold) radiotherapy represents a high-precision treatment approach that substantially minimizes radiation exposure to vital organs such as the heart, thus enhancing protection of the…
- Trial name
- NCT06488391
- Testing
- Using a Portable Visualized Device for Self-Directed Breathing Training
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Jianjun Lai