Clinical trials: Bronchiolitis
Acute Viral Bronchiolitis
KL-6 Protein as a Biomarker of Lung Injury in Viral Bronchiolitis
Serum KL-6 protein has been described as a biomarker of epithelial lung injury in Respiratory Syncytial Virus bronchiolitis. The investigators can imagine that epithelial injury intensity has consequences on immediate and later…
- Trial name
- NCT01437956
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Bronchiolitis
Studying Innate Immune Responses in Infants With Bronchiolitis
This study aims to establish whether impaired innate immune responses are associated with severity of Respiratory syncytial virus (RSV) infection.
- Trial name
- NCT01159795
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Acute Respiratory Tract Infections
Study of Vitamin D for the Prevention of Acute Respiratory Infections in Children
The main purpose of this study is to determine whether weekly oral vitamin D supplementation is effective to prevent acute respiratory tract infections in children.
- Trial name
- NCT02046577
- Testing
- Vitamin D3
- Where
- 3 sites in Chile
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Uremia, Uremia; Chronic
Dynamic Breath VOC Profiling as a Non-invasive Tool to Assess Hemodialysis Adequacy
What is this study about? This is an observational study. The goal is to find out whether tiny chemicals in breath, called volatile organic compounds (VOCs), can help show if a hemodialysis session works well enough ("dialysis…
- Conditions
- Uremia, Uremia; Chronic, Hemodialysis
- Trial name
- NCT07189741
- Testing
- hemodialysis
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Second People's Hospital, Shanghai
Common Cold, Pharyngitis
Supporting Parents to Choose Wisely
The goal of this multi-method study including a randomized control trial and qualitative interviews is to see how useful blogshots (an image that summarizes information) are at helping parents increase their knowledge and manage…
- Conditions
- Common Cold, Pharyngitis, Acute Otitis Media, Acute Asthma
- Trial name
- NCT06005337
- Testing
- Blogshots 1-3, Blogshots 4-6
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Mechanical Ventilation Complication, Pneumonia
Mechanically Ventilated Children and Pacifiers
Mechanical ventilation is a life support system developed to support or restore normal lung functions. Children who are connected to mechanical ventilator, separation from family in intensive care environment, getting away from…
- Conditions
- Mechanical Ventilation Complication, Pneumonia, Bronchiolitis
- Trial name
- NCT05566184
- Testing
- Modified pacifier
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hitit University
Chronic Granulomatous Disease (CGD), X-Linked Severe Combined Immune Deficiency (XSCID)
Evaluation of Patients With Immune Function Abnormalities
This study will evaluate patients with abnormal immune function that results in recurrent or unusual infections or chronic inflammation.
- Conditions
- Chronic Granulomatous Disease (CGD), X-Linked Severe Combined Immune Deficiency (XSCID), Leukocyte Adhesion Deficiency 1 (LAD), Graft Versus Host Disease (cGvHD)
- Trial name
- NCT00128973
- Where
- United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Kidney Disease, Left Ventricular Hypertrophy
Do Xanthine Oxidase Inhibitors Reduce Both Left Ventricular Hypertrophy and Endothelial Dysfunction in Cardiovascular Patients With Renal Dysfunction?
Cardiovascular related disease is the main cause of death in patients with kidney disease, and "oxidative stress" is thought to be a major contributor by promoting thickening of the heart muscle and stiffening of the arteries.
- Trial name
- NCT00688480
- Testing
- Allopurinol
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- A. D. Struthers
Gingivitis; Chronic
Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis
This pilot study aims to evaluate the effects of miswak use on the oral biological environment by comparing biochemical parameters obtained from saliva and dental plaque samples collected from individuals who use miswak and…
- Trial name
- NCT07689786
- Testing
- Miswak, Toothpaste
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Acute Bronchiolitis Due to Respiratory Syncytial Virus
Phase 1 Study to Evaluate the Safety and Immunogenicity of a Candidate Vaccine Against Respiratory Syncytial Virus
The primary and secondary objectives of this Phase 1 study are respectively to assess the safety and the immunogenicity of two administrations of the RSV vaccine candidate at three different doses.
- Trial name
- NCT04519073
- Testing
- V-306 candidate vaccine
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Virometix
Bronchiolitis
Bronchiolitis Recovery and the Use of High Efficiency Particulate Air (HEPA) Filters
This is a multi-center, parallel, double-blind, randomized controlled clinical trial. Children <12 months of age hospitalized with bronchiolitis are randomized 1:1 to receive a 24-week home intervention with filtration units…
- Trial name
- BREATHE (NCT05615870)
- Testing
- Winix 5500-2 HEPA filtration units
- Where
- 17 sites in United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- IDeA States Pediatric Clinical Trials Network
Gingivitis; Chronic, Smoking
Synbiotic as an Adjunct to Mechanical Treatment of Gingivitis
The aim of this study is to evaluate the efficacy of oral administration of synbiotic tablets on the clinical parameters and the levels of selected inflammatory mediators in gingival crevicular fluid (GCF) in smokers and…
- Trial name
- NCT03455192
- Testing
- Synbiotic Supplement
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Pneumonia, Bronchiolitis
Neutrophil Monocyte Lymphocyte Ratios in Pediatric Chest Infections
This prospective cohort study aims to evaluate neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, and neutrophil-to-monocyte ratio in children with lobar pneumonia, bronchiolitis, and bronchopneumonia compared with…
- Trial name
- NCT07888049
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Asthmatic Bronchitis
Gene Expression Profile and Inflammation Profile of Classic Asthma, Cough Variant Asthma and Eosinophilic Bronchitis
This study aims to identify and validate the gene expression differentials of peripheral blood mononuclear cells and differential inflammation profiles and other aspects in classic asthma, cough-variant asthma and eosinophilic…
- Trial name
- NCT02555345
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- State Key Laboratory of Respiratory Disease
Chronic Low-back Pain
Music-based Treatments and Pain: Underlying Mechanisms and the Beneficial Effects of Music-Based Treatments
The purpose of this study is to understand the mechanisms that underlie the beneficial effects of music-based treatments in individuals with moderate to severe chronic low back pain
- Trial name
- NCT05578781
- Testing
- Music Therapy, Music Medicine, Control group
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cholecystitis, Chronic
Outcomes of Three Ports Versus Four Ports Laparoscopic Cholecystectomy, Sohag General Surgery Department Experience
To compare the outcomes of three ports and four ports Laparoscopic Cholecystectomy
- Trial name
- NCT06264115
- Testing
- Laparoscopic Cholecystectomy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Chronic Pain, Back Pain Lower Back Chronic
Mind-body Treatments for Chronic Back Pain
Participants with chronic back pain will complete an online prescreen. They will then be randomized to one of two different studies: a placebo vs. waitlist study or a psychotherapy vs.
- Conditions
- Chronic Pain, Back Pain Lower Back Chronic, Back Pain, Low
- Trial name
- NCT03294148
- Testing
- Psychotherapy Treatment for Chronic Back Pain
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Bronchiolitis
Study of Pneumococcal Carriage in RSV Bronchiolitis in Infants Aged 6 to 18 Months
The relationship between RSV (human respiratory syncytial virus) infections and invasive infections or pneumonia caused by Streptococcus pneumoniae has been observed epidemiologically for several years.
- Trial name
- Synergy (NCT06722716)
- Testing
- Swab collection
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Migraine, Healthy
Molecular and Functional PET-fMRI Measures of Analgesia in Migraine
The placebo effect is a phenomenon that has experienced major advances of its understanding in the last decade. However, mechanisms of placebo analgesia in chronic pain patients have yet to be compared to healthy subjects.
- Trial name
- NCT01970943
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pulmonary Disease, Chronic Obstructive, Sexual Health
Impact of COPD on Sexual Health, Loneliness, and Well-being
Summary Person-centered care is a hot topic within healthcare, yet communication about patients' sexual health and intimacy issues remain too hot to handle within healthcare.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Sexual Health, Loneliness, Well-Being, Psychological
- Trial name
- NCT06240078
- Where
- Denmark
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- Vejle Hospital