Clinical trials: Bronchitis
Cystic Fibrosis, Primary Ciliary Dyskinesia
Multiple Breath Washout, a Clinimetric Dataset
Monitoring patients with chronic, inflammatory airways disease particularly in the early stages is hampered by the relative insensitivity of current outcome measures to detect subtle changes.
- Conditions
- Cystic Fibrosis, Primary Ciliary Dyskinesia, Bronchiectasis, Asthma
- Trial name
- NCT03320382
- Testing
- Multiple breath washout testing
- Where
- United Kingdom
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Gingivitis; Chronic, Smoking
Synbiotic as an Adjunct to Mechanical Treatment of Gingivitis
The aim of this study is to evaluate the efficacy of oral administration of synbiotic tablets on the clinical parameters and the levels of selected inflammatory mediators in gingival crevicular fluid (GCF) in smokers and…
- Trial name
- NCT03455192
- Testing
- Synbiotic Supplement
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Pneumonia, Bronchiolitis
Neutrophil Monocyte Lymphocyte Ratios in Pediatric Chest Infections
This prospective cohort study aims to evaluate neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, and neutrophil-to-monocyte ratio in children with lobar pneumonia, bronchiolitis, and bronchopneumonia compared with…
- Trial name
- NCT07888049
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Asthmatic Bronchitis
Gene Expression Profile and Inflammation Profile of Classic Asthma, Cough Variant Asthma and Eosinophilic Bronchitis
This study aims to identify and validate the gene expression differentials of peripheral blood mononuclear cells and differential inflammation profiles and other aspects in classic asthma, cough-variant asthma and eosinophilic…
- Trial name
- NCT02555345
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- State Key Laboratory of Respiratory Disease
Chronic Low-back Pain
Music-based Treatments and Pain: Underlying Mechanisms and the Beneficial Effects of Music-Based Treatments
The purpose of this study is to understand the mechanisms that underlie the beneficial effects of music-based treatments in individuals with moderate to severe chronic low back pain
- Trial name
- NCT05578781
- Testing
- Music Therapy, Music Medicine, Control group
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cholecystitis, Chronic
Outcomes of Three Ports Versus Four Ports Laparoscopic Cholecystectomy, Sohag General Surgery Department Experience
To compare the outcomes of three ports and four ports Laparoscopic Cholecystectomy
- Trial name
- NCT06264115
- Testing
- Laparoscopic Cholecystectomy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Chronic Pain, Back Pain Lower Back Chronic
Mind-body Treatments for Chronic Back Pain
Participants with chronic back pain will complete an online prescreen. They will then be randomized to one of two different studies: a placebo vs. waitlist study or a psychotherapy vs.
- Conditions
- Chronic Pain, Back Pain Lower Back Chronic, Back Pain, Low
- Trial name
- NCT03294148
- Testing
- Psychotherapy Treatment for Chronic Back Pain
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Bronchiolitis
Study of Pneumococcal Carriage in RSV Bronchiolitis in Infants Aged 6 to 18 Months
The relationship between RSV (human respiratory syncytial virus) infections and invasive infections or pneumonia caused by Streptococcus pneumoniae has been observed epidemiologically for several years.
- Trial name
- Synergy (NCT06722716)
- Testing
- Swab collection
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Migraine, Healthy
Molecular and Functional PET-fMRI Measures of Analgesia in Migraine
The placebo effect is a phenomenon that has experienced major advances of its understanding in the last decade. However, mechanisms of placebo analgesia in chronic pain patients have yet to be compared to healthy subjects.
- Trial name
- NCT01970943
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pulmonary Disease, Chronic Obstructive, Sexual Health
Impact of COPD on Sexual Health, Loneliness, and Well-being
Summary Person-centered care is a hot topic within healthcare, yet communication about patients' sexual health and intimacy issues remain too hot to handle within healthcare.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Sexual Health, Loneliness, Well-Being, Psychological
- Trial name
- NCT06240078
- Where
- Denmark
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- Vejle Hospital
Lower Respiratory Tract and Lung Infections, Ventilator Lung
Copeptin: Disease Severity Indicator
Copeptin serves as a biomarker emanating from the pituitary gland, functioning as the precursor to arginine vasopressin (AVP). Its role in the regulation of endothelial dysfunction, inflammation, and water-electrolyte balance has…
- Conditions
- Lower Respiratory Tract and Lung Infections, Ventilator Lung, Bronchopneumonia, Bronchitis
- Trial name
- NCT06211985
- Testing
- Copeptin level measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Berker Okay
Other Preterm Infants, Vitamin D Deficiency
The Effect of Vitamin D Administration to Premature Infants on Vitamin D Status and Respiratory Morbidity
This trial objective is to assess whether doubling the daily intake of vitamin D improves serum vitamin D levels and serves as primary prevention of respiratory infections and asthma in premature infants.
- Conditions
- Other Preterm Infants, Vitamin D Deficiency, Bronchiolitis, Asthma
- Trial name
- NCT02404623
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Hepatitis B, Chronic
A Real-world Study: Analysis of the Efficacy of Antiviral Therapy in CHB Patients Over 30 Years Old, HBV DNA Positive and ALT Normal
This is a prospective observational study of CHB patients who have not received antiviral treatment but HBV DNA are positive.Investigators aim to explore the antiviral effect and influencing factors of patients over 30 years old…
- Conditions
- Hepatitis B, Chronic, Treatment
- Trial name
- NCT07637214
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Autoimmune Diseases, Sickle Cell Disease
Microvascular and Fibrosis Imaging Study
In this study, Laser Doppler Flowmetry (LDF), Laser Doppler Imaging (LDI), Orthogonal Polarization Spectral Imaging (OPSI), Nail fold video capillaroscopy (NVC) and Optical Coherence Tomography (OCT) will be used to assess…
- Conditions
- Autoimmune Diseases, Sickle Cell Disease, Chronic Graft Versus Host Disease
- Trial name
- NCT01758250
- Testing
- Acoustic Radiation Force Impulse (ARFI), Laser Doppler Flowmetry (LDF), Laser Doppler Perfusion Imaging (LDI)
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Duke University
COPD, Emphysema
Leukocyte Function in Chronic Obstructive Pulmonary Disease (COPD)
The aim of this study is to investigate the mechanisms whereby leukocytes are recruited to the lung in chronic obstructive pulmonary disease (COPD) and cause tissue destruction.
- Conditions
- COPD, Emphysema, Chronic Bronchitis
- Trial name
- NCT00147082
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Venous Insufficiency
Venavine Intensive® in the Treatment of Symptoms Associated With Chronic Venous Insufficiency
Chronic Venous Insufficiency (CVI) occurs when the veins in the lower limbs can no longer sufficiently pump enough blood back to the heart.
- Trial name
- NCT02483962
- Testing
- Gelatine capsule, Venavine Intensive®
- Where
- South Africa
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Johannesburg
Upper Respiratory Tract Infections, Rhinopharyngitis
Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation
This multicentric, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Conditions
- Upper Respiratory Tract Infections, Rhinopharyngitis, Sore Throat, Sinusitis
- Trial name
- NCT01315418
- Testing
- 1-Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), 2-Non fermented dairy product (control)
- Where
- France
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Respiratory Disease, Bronchiolitis, Viral
SWISH Trial (Strategies for Weaning Infants on Supportive High Flow)
Bronchiolitis is a common type of chest infection that tends to affect babies and young children under a year old. In older children and adults, the same viruses that cause bronchiolitis lead to the 'common cold'.
- Conditions
- Respiratory Disease, Bronchiolitis, Viral, Infant Morbidity
- Trial name
- SWISH (NCT04287959)
- Testing
- High flow nasal cannula support
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cardiff and Vale University Health Board
Oral Lichen Planus, Mucous Membrane Pemphigoid
Dexamethasone Solution and Dexamethasone in Mucolox™
Topical steroid therapy is considered the first line of treatment for Oral Inflammatory Ulcerative Diseases with current treatment regimens requiring multiple application or rinses daily.
- Conditions
- Oral Lichen Planus, Mucous Membrane Pemphigoid, Pemphigus Vulgaris, Chronic Graft-versus-host-disease
- Trial name
- NCT04540133
- Testing
- dexamethasone 0.5mg/5ml solution, dexamethasone 0.5mg/5ml solution in Mucolox™
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Aphasia, Language
tDCS as an Adjuvant to Intensive Speech Therapy for Chronic Post Stroke Aphasia
The purpose of this study is to determine if transcranial direct current stimulation (tDCS) in conjunction with intensive speech therapy will improve sentence production and word retrieval in individuals with chronic post stroke…
- Trial name
- NCT02801864
- Testing
- Real tDCS, Intensive Speech Therapy
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Austin Speech Labs