Clinical trials: Burns
ICU Patients With Indication of Sedation
A Pharmacokinetic Study of Sevoflurane Inhalation in Burn ICU Patients
Comparing a pharmacokinetic model of a short sevoflurane sedation in burn ICU patients with control ICU patients.
- Trial name
- SEVOBURN (NCT02048683)
- Testing
- Short term sedation with sevoflurane in ICU
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Clermont-Ferrand
Burns
Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents
This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in adults and adolescents with partial deep dermal and full thickness burns.
- Trial name
- NCT03227146
- Testing
- EHSG-KF, STSG
- Where
- 6 sites in Italy, Netherlands and 1 more
- Volunteers
- 14 people
- Sponsor
- CUTISS AG
Burns
Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Children
This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in children with partial deep dermal and full thickness burns.
- Trial name
- NCT03229564
- Testing
- EHSG-KF, STSG
- Where
- 4 sites in Italy, Netherlands and 1 more
- Volunteers
- 12 people
- Sponsor
- CUTISS AG
Burns
SASS 2 : Self Assembled Skin Substitute for the Autologous Treatment of Severe Burn Wounds in Acute Stage of Burn Trauma
This clinical trial is designed to assess the safety, effectiveness and benefits of Self Assembled Skin Substitute SASS grafts as a permanent skin replacement for the treatment of full-thickness burn wounds that require permanent…
- Trial name
- NCT02350205
- Testing
- Self assembled skin substitute (SASS)
- Where
- 8 sites in Canada
- Volunteers
- 52 people
- Sponsor
- CHU de Quebec-Universite Laval
Spinal Cord Injuries, Polytrauma
Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Intensive Rehabilitation
The use of conditioning open-label placebo (COLP) will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, and burn injury.
- Conditions
- Spinal Cord Injuries, Polytrauma, Burn Injury, Pain Management
- Trial name
- COLP (NCT03906721)
- Testing
- Oxycodone, Essential Oil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Spaulding Rehabilitation Hospital
Burns, First Aid
Effects of the Mobile Application Developed for Families After the Earthquake on First Aid Knowledge and Burn Prevention
The aim of this project was to determine the effect of the burn prevention and first aid mobile application developed for families living in tent cities and container houses after the earthquake on the burn prevention and first…
- Conditions
- Burns, First Aid, Mobile Application, Earthquake
- Trial name
- NCT06155149
- Testing
- Mobile application, Family Information Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Unintentional Burn Injury, Depression
Integrated Case Management for Burns Care in Pakistan
To test whether a culturally adapted multicomponent intervention for improving burns care and patient/family rehabilitation is effective in improving survival among burn victims in Pakistan and is cost-effective.
- Conditions
- Unintentional Burn Injury, Depression, Anxiety, Burns
- Trial name
- BURNS (NCT06559501)
- Testing
- Integrated case manager care
- Where
- 11 sites in Pakistan
- Volunteers
- 1,045 people
- Sponsor
- Pakistan Institute of Living and Learning
Burns, Pain, Procedural
Virtual Reality for Pain and Fear in Children With Burns
Burn injuries are very painful for children, especially during dressing changes when the wound is cleaned and re-bandaged. This procedure, while necessary, can cause pain, fear, and distress that may make children afraid of…
- Conditions
- Burns, Pain, Procedural, Pain, Acute, Fear
- Trial name
- VR-PFB (NCT07740980)
- Testing
- Virtual Reality (VR) Distraction, Standard Burn Dressing Care
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Burns, Acute Pain
VR-PAT During Home Burn Dressings - Multisite
This study will evaluate the effectiveness of smartphone Virtual Reality Pain Alleviation Therapy (VR-PAT) as a pain distraction tool during repeated at-home burn dressing changes among 100 children (age 6-17 years) with a burn…
- Conditions
- Burns, Acute Pain, Procedural Pain, Injuries
- Trial name
- NCT05673551
- Testing
- VR-PAT
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Nationwide Children's Hospital
Burn Injury
Clinical Assessment of Protopic® Ointment in Deep Partial-Thickness Burns
There is currently no standard treatment to prevent burn depth conversion in partial-thickness burns. Conversion into deeper wounds is associated with higher complications and morbidity.
- Trial name
- NCT05856994
- Testing
- Tacrolimus ointment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Vanderbilt University Medical Center
Burn; Multiple Body Regions, Max. Second Degree, Third-Degree Burn
Safety, Tolerability and Efficacy of Nefopam Cream in Burn Patients
Burn patients very commonly develop abnormal scars after injury which can be red, raised or elevated, painful and very itchy. They can prevent normal movement of hands and other joints and lead to ugly deformities which makes…
- Conditions
- Burn; Multiple Body Regions, Max. Second Degree, Third-Degree Burn, Burn Degree Second
- Trial name
- NCT04685577
- Testing
- Nefopam
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Anxiety, Burn Pain
Hologram Burn Dressing on Pain, Anxiety, Fear, Patient Satisfaction, and Physiological Parameters
Burn injuries are a significant global health problem, leading to serious physical, psychological, and social challenges for affected individuals.
- Conditions
- Anxiety, Burn Pain, Burn Patients, Fear
- Trial name
- NCT07244653
- Testing
- Showing videos with holograms
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Gamze BULUT
Burns, Contracture Scar
Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar
The goal of this study is to explore if an adipose-based therapeutic strategy can treat contracted scars secondary to soft-tissue burn wounds in injured individuals, especially those with severe burns or soft-tissue loss.
- Conditions
- Burns, Contracture Scar, Surgical Injury
- Trial name
- NCT06857435
- Testing
- Full Thickness Skin Graft (FTSG), Base of wound fat graft with Split Thickness Skin Graft (STSG) Reconstruction (Autologous Layered Composite Grafting).
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Burns, Contracture Scar
Autologous Point-of-Care Adipose Therapy: Recent Injury
The goal of this study is to explore if an adipose-based therapeutic strategy can treat full-thickness soft-tissue trauma wounds in injured individuals, especially those with severe burns or soft-tissue loss.
- Conditions
- Burns, Contracture Scar, Surgical Injury
- Trial name
- NCT06857448
- Testing
- Split Thickness Skin Graft (STSG), Base of wound fat graft with STSG Reconstruction (Autologous Layered Composite Grafting).
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Pittsburgh
Burn, Coagulation, Blood
Thromboelastography to Study Burn Coagulopathy
This pilot study examines the use of thromboelastography (TEG), a specialized blood test, to evaluate clotting abnormalities in burn patients.
- Trial name
- NCT06879509
- Testing
- Thromboelastography
- Where
- United States
- Sponsor
- Francesco Egro
Burn Pit Exposure
Tele-Exercise for MERP
During Operations Desert Shield and Desert Storm, Veterans in combat were exposed to a variety of airborne hazards, including oil well fire smoke, emissions from burn pits, and other substances associated with negative health…
- Trial name
- TEMPO (NCT07018466)
- Testing
- Tele-exercise, Standard of Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Superficial and Superficial Partial Thickness Burns
Effectiveness of Alovera Gel vs 1% Silver Sulfadiazine in Superficial Partial Thickness Burn Patients in Pediatric Population.
This prospective randomized controlled study aims to compare the effectiveness of Aloe vera gel versus 1% silver sulfadiazine in the treatment of superficial and superficial partial-thickness burns in the pediatric population.
- Trial name
- NCT07716605
- Testing
- Silver sulfadiazine 1%cream, Alovera gel
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
Burn
Vitamin E Supplementation in Burned Patients
A dietary antioxidant, alpha-tocopherol, will be used to potentially attenuate Vitamin E short- and long-term losses in plasma and adipose, reverse the oxidative stress of burn injury and, in the process, decrease the secondary…
- Trial name
- NCT01749371
- Testing
- Vitamin E
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns
Gaming Based PNF on Spatiotemporal Parameters in Upper Limb Burned Patients
Burn injuries are among the most severe forms of trauma, often leading to significant physical and psychological challenges. The rehabilitation process for burn patients, particularly those with upper limb injuries, is complex…
- Trial name
- NCT07183943
- Testing
- Proprioceptive neuromuscular facilitation (PNF), Visual reality (VR), PNF and VR
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- MTI University
Microvesicle Particles, Thermal Burn
Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle Release
The purpose of this study is to determine the amount of substances contained in skin known as microvesicle particles (MVP). The hypothesis to be tested in this study is that treatment with a single dose of 75mg of amitriptyline…
- Trial name
- NCT07640061
- Testing
- Amitriptyline
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wright State University