Clinical trials: Burns
Burns, Thermal Injury
Optimal Heating Temperature in Major Burns Patients
pre and post intervention quasi-experimental epidemiological study without a control group will be carried out in large burned patients that will evaluate the influence on metabolic expenditure of the inclusion of active external…
- Conditions
- Burns, Thermal Injury, Nurse's Role
- Trial name
- NCT04396951
- Testing
- Active external overheating with heating plate, Aragonia ® MTC 400, Active external overheating with air blanket, Equator Level 1® de Smiths Medical
- Volunteers
- 34 people
- Sponsor
- University Rovira i Virgili
Aromatherapy
Effect of Aromatherapy on Pain, Anxiety and Sleep Quality in Burn Patients
This study, which was designed as a randomized placebo-controlled experimental study, was conducted to determine the effect of inhalation aromatherapy with lavender essential oil on pain, anxiety and sleep quality in burn…
- Trial name
- NCT05728190
- Testing
- steril/salin water, Lavender essential oil
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sema Koçaşlı
Retinal Vein Occlusion, Treatment
Ranibizumab Treatment for Macular Edema Secondary to Retinal Vein Occlusion
Retinal vein occlusion (RVO) may lead to series of complications including retinal ischemia, macular edema (ME) and induce vision impairment.
- Conditions
- Retinal Vein Occlusion, Treatment, Photocoagulation Burn to Retina, Ranibizumab
- Trial name
- NCT04062370
- Testing
- Ranibizumab, laser photocoagulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Burns, Infection
Once Daily Aminoglycoside Pharmacokinetics and Optimal Dosing in the Burn Population: A Prospective Study
Effective antimicrobial use in the burn population is important since this population is at an increased risk for infections during their stay in hospital as a result of their burn injury.
- Trial name
- NCT02269969
- Testing
- Tobramycin
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sandra Walker
Burn Injury
Evaluation of Single-dose Pharmacokinetics of Intravenous Daptomycin in Patients With Thermal Injury
The purpose of this study is to determine single dose pharmacokinetics of daptomycin consecutively in 10 patients on three different time points after severe burn injury.
- Trial name
- NCT02241941
- Testing
- Daptomycin
- Where
- Switzerland
- Sponsor
- University of Zurich
Melanoma (Skin)
Wearable Device Intervention to Improve Sun Behaviors in Melanoma Survivors
Over 5 million new cases of skin cancer are diagnosed in the United States each year, more than all other cancers combined. Most of these cases are caused by excess exposure to ultraviolet radiation from the sun and artificial…
- Trial name
- NCT03927742
- Testing
- Shade + app with messaging, Shape + app without messaging
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- University of Minnesota
Depression, Anxiety
A Prospective Study of Body Image, Social Avoidance and Distress and Psychological Functioning in Burn Patients
The present study seeks to examine the course of body image, social avoidance and psychosocial aspects of depression and anxiety over time in burn patients.
- Conditions
- Depression, Anxiety, Body Image
- Trial name
- NCT01136070
- Where
- United States
- Sponsor
- Saint Elizabeth Regional Medical Center
Human Herpes Virus, Herpes Simplex Virus
Review of Human Herpes Viruses in Burns
Herpes simplex virus, cytomegalovirus and varicella zoster virus infection are purported to play a pivotal role in morbidity and mortality in burns.
- Conditions
- Human Herpes Virus, Herpes Simplex Virus, Varicella-zoster Virus, Chickenpox
- Trial name
- NCT02452229
- Testing
- Review of the Literature for Human Herpes Virus infections
- Volunteers
- 10,267 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns
Early Versus Late Upper Extremity Mobilization After Meshed / Sheet Split Thickness Skin Autograft on Wound Healing in Adult Burn Patients
STSGs are used to close wounds and minimize infections. After receiving a meshed or sheet split-thickness skin graft (STSG) to the upper extremity or hand for a thermal burn injury, burn surgeons use different methods to improve…
- Trial name
- EXTREMA (NCT06143683)
- Testing
- Early Mobilization, Late Mobilization
- Volunteers
- 100 people
- Sponsor
- Hamilton Health Sciences Corporation
Severe Burns, Acute Kidney Injury
Association of Continuous Renal Replacement Therapy With Mortality and Length of Stay in Critically Burned Patients
This retrospective observational study aims to investigate the clinical outcomes of critically ill burn patients who underwent continuous renal replacement therapy (CRRT).
- Conditions
- Severe Burns, Acute Kidney Injury, Critical Illness
- Trial name
- CRRT-BURN (NCT07195565)
- Where
- Turkey (Türkiye)
- Volunteers
- 238 people
- Sponsor
- Pinar Timur Tasci
Traumatic Skin Loss, 2nd and 3rd Degree Burn, Post Tumour Excision - Raw Areas Undergoes Split- Thickness Skin Grafts
Evaluation of the Use of Minced Skin Grafts for Promoting Donor Site Wound Healing After Split-Thickness Skin Grafting
Split-thickness skin grafting (STSG) is one of the most commonly performed procedures to achieve wound closure. Most studies are concerned on improving the appearance of scars and shortening the healing time of the recipient…
- Trial name
- NCT06488612
- Testing
- Minced skin grafts for donor site
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Burns
A Postmarket Randomized Study of the Treatment of Superficial Partial-Thickness Burns Using Two Dressings
The purpose of this research study is to compare the rate of healing, the infection or complication rate, pain perception and scarring from burn injuries using two types of burn dressings.
- Trial name
- NCT01067729
- Testing
- AWBAT Wound Dressing, AWBAT™, Biobrane®
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aubrey Inc.
Antibiotics, Severe Burn
Determining Drug Levels of Beta-lactam Antibiotics in Severe Burned Patients
At antibiotic stewardship of the University Hospital of Schleswig-Holsten it was noticed that there are much less studies measuring drug levels in severe burned patients than are required.
- Conditions
- Antibiotics, Severe Burn, Intensive Care
- Trial name
- MSBV (NCT03335137)
- Testing
- Drug Level Monitoring
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- University Hospital Schleswig-Holstein
Burns Second Degree
Thermal Imaging and Pediatric Burns
The need to cover a burn with a skin graft is determined primarily by its depth. In fact only burns of the second deep degree or the third degree are likely to be grafted.
- Trial name
- FLIRPED (NCT03702972)
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Burns, Wound of Skin
Amnion Wound Covering for Enhanced Wound Healing
The purpose of this research study is to find our if human amnion membrane powder can be safely used as a covering for wounds and can improve the condition of skin graft donor sites.
- Conditions
- Burns, Wound of Skin, Skin Wound
- Trial name
- NCT03754218
- Testing
- Amnion Membrane Powder, SOC Wound Covering
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Wake Forest University Health Sciences
Scars, Hypopigmented Scar
Treatment of Hypopigmented Scars With Bimatoprost
Patients who have hypo-pigmented burn scar will have two scars chosen and randomized to treated scar and control scar. The subject will then have both scars treated with fractional ablative CO2 laser (FLSR).
- Conditions
- Scars, Hypopigmented Scar, Hypopigmented Skin, Burn Scar
- Trial name
- NCT06122090
- Testing
- Bimatoprost, Saline
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Burn Surgery
Comparison of AWBAT™-D and MEPILEX® AG for Treatment of Donor Sites in Burn Surgery
The purpose of this study is to examine AWBAT™-D compared to Mepilex® Ag for the treatment of donor sites in burn surgery.
- Trial name
- NCT00974597
- Testing
- AWBAT™-D and Mepilex® Ag dressings
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aubrey Inc.
Burn, Pain
Low-Dose Ketamine Infusion During Burn Wound Care
The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use.
- Conditions
- Burn, Pain, Dissociation, Opioid
- Trial name
- IMPROVE (NCT06506565)
- Testing
- Ketamine, 0.9% NaCl
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Tennessee
Burn Surgery
Effect of Vitamin D in Burn Patients
The purpose of this study is to evaluate pre-operative vitamin D levels in patients with burn injuries and evaluate the effect of vitamin D on postoperative complications and duration of hospitalization.
- Trial name
- NCT03884036
- Testing
- Vitamin D
- Where
- South Korea
- Volunteers
- 264 people
- Sponsor
- Hangang Sacred Heart Hospital
Deep Full-thickness Burn Injury (Disorder)
Evaluation of Safety and Efficacy of realSKIN® (Skin Xenotransplant) for Complete Closure of Severe Burn Wounds
This is a Phase 1/2, Open-label, Multi-center, Clinical Trial to evaluate the safety, tolerability, and efficacy of realSKIN® to provide complete wound closure of severe and extensive deep-partial and full-thickness burn wounds.
- Trial name
- NCT03695939
- Testing
- realSKIN (skin xenotransplant), Human Cadaver Allograft
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- XenoTherapeutics, Inc.