Clinical trials: Burst Suppression
Burst Suppression, General Anesthesia
Interrater Variability for the Identification of Anesthetic-induced Burst Suppression EEG
Burst suppression describes a specific EEG pattern that can generally indicate a too deep general anesthesia. The pathophysiology of anesthetic-induced Burst Suppression may be distinctly different from the pathophysiology of…
- Conditions
- Burst Suppression, General Anesthesia, Electroencephalogram
- Trial name
- NCT05508386
- Testing
- MATLAB-based interface, showing 50 EEG traces, classification of the EEG-pattern as Burst Suppression possible, yes, no.
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Postoperative Delirium
Association Between Burst Suppression During Anesthetic Induction With Postoperative Delirium in Cardiac Surgery
The population over 65 years of age will be increasingly exposed to surgical procedures that require general anesthesia. Postoperative delirium is one of the main causes of preventable postoperative morbidity in the elderly…
- Trial name
- NCT04713644
- Testing
- Standardized Propofol Administration
- Where
- Chile
- Volunteers
- 78 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Propofol Overdose, EEG
Dose-response Curves Between Propofol and Intraoperative Electroencephalographic Patterns
In the world, 230 million surgeries are performed per year and a significant part is performed in patients over 65 years of age.
- Trial name
- NCT04345926
- Testing
- Propofol, Electroencephalogram recording
- Where
- 2 sites in Chile
- Volunteers
- 15 people
- Sponsor
- University of Chile
Somatosensory Evoked Potentials, and Electroencephalography
SEP Changes During Deep Anesthesia
The relation between burst and suppression periods in transcranial and direct cortical recorded EEG with cortical amplitudes median nerve somatosensory evoked potentials is studied.
- Trial name
- SEPinBSP (NCT02394002)
- Testing
- Propofol
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Andrea Szelenyi
Anesthesia Brain Monitoring
Effects of Aminophylline Bolus on TCI (Target Controlled Infusion) Concentrations at Burst Suppression Occurence
Aminophylline is an intravenous drug commonly utilized for asthma. However, some preclinical studies and few case reports and case series have described its effects in lightining the anesthestic plan during Propofol anaesthesia…
- Trial name
- TCI (NCT06134037)
- Testing
- Aminophylline
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Padova
Burst Suppression, Electroencephalogram
Impact of Interscalene Block Combined With General Anesthesia on Burst Suppression in Shoulder Surgery Patients
This prospective, randomized, double-blind clinical study aimed to investigate the effects of combining general anesthesia with an interscalene brachial plexus block (ISB) on burst suppression ratio (BSR) and…
- Conditions
- Burst Suppression, Electroencephalogram, Interscalene Brachial Plexus Block
- Trial name
- NCT07081672
- Testing
- Ultrasound-guided interscalene brachial plexus block (ISB), General Anesthesia (control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bezmialem Vakif University
Tinnitus
Residual Inhibition of 40 Hz Burst Sound in Tinnitus Patients
Tinnitus affects 10-15% of adults and is frequently associated with impaired quality of life, anxiety, and sleep disturbance. Conventional sound therapies based on continuous masking provide inconsistent and short-lived relief…
- Trial name
- NCT06646302
- Testing
- Personalized 40 Hz Broadband Stimulation, 40 Hz Pure Tone Stimulation, Continuous Broadband Noise
- Where
- China
- Volunteers
- 363 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Anesthesia, Neurocognitive Disorders
Neurocognitive Disorders After Major Surgery in Elderly
The objective of the study is to investigate, in patients aged 70 years and over undergoing major non-cardiac surgery, the effect of electroencephalic (EEG)-guided anesthesia on postoperative neurocognitive disorders when…
- Trial name
- POEGEA (NCT04825847)
- Testing
- BIS monitor, Control group
- Where
- Canada
- Volunteers
- 314 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Bispectral Index Monitoring, Burst Suppression
Relationship Between Induction Burst Suppression and Bispectral Index
The purpose of this study is to understand whether certain brain activity patterns that can appear at the beginning of anesthesia are related to how deep anesthesia remains during the operation.
- Conditions
- Bispectral Index Monitoring, Burst Suppression, Total Intravenous Anesthesia
- Trial name
- NCT07557433
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Amasya University
Craniotomy, Transphenoidal Pituitary Resection
A Comparative Study of Global 12 Lead Electroencephalogram to Frontal SedlineTM Electroencephalogram
The fundamental reason for comparing the ability of the Frontal Sedline TM Electroencephalogram (PSA EEG) to standard Global 12 Lead Electroencephalogram (EEG) for burst suppression detection is to determine if a less expensive…
- Trial name
- NCT01256749
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Loma Linda University
Laparoscopic Cholecystectomy, Postoperative Pain
Subcostal TAP Block and EEG Dynamics in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is a commonly performed minimally invasive surgical procedure. Despite its minimally invasive nature, surgical stimulation and pneumoperitoneum may cause pain-related physiological and…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Intraoperative Nociception
- Trial name
- NCT07818954
- Testing
- Remifentanil, Ultrasound-Guided Subcostal Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Geriatric Patient Care Improvement, Postoperative Delirium (POD)
The Effects of Anesthesia Depth Monitoring on Postoperative Recovery and Cognitive Functions in the Geriatric Patient Population
This study will be conducted on patients aged 65 and older scheduled for surgery due to lumbar or cervical disc herniation. General anesthesia is routinely used for these types of surgeries in the hospital.
- Conditions
- Geriatric Patient Care Improvement, Postoperative Delirium (POD), Burst Suppression
- Trial name
- NCT06844279
- Testing
- Control Group: Standard Hemodynamic Monitoring, Processed Electroencephalogram (BIS Index), Processed Electroencephalogram (DSA Mode)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Aslıhan Güleç
Anesthesia, General, Electroencephalography
Anesthesia and EEG Discontinuity in Infants
This study is a randomized controlled trial to evaluate whether EEG-guided calibration of inhalation agents can reduce occurrence of EEG discontinuity in infants during general anesthesia.
- Conditions
- Anesthesia, General, Electroencephalography, Infant, Anesthesia, Inhalation
- Trial name
- NCT05906225
- Testing
- EEG guided anesthesia, Conventional anesthesia
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Seoul National University Hospital
Post-operative Delirium, Cognitive Dysfunction
Effect of Epidural Analgesia on Burst Suppression
It has been shown in previous studies that burst suppression has an effect on the development of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD).
- Conditions
- Post-operative Delirium, Cognitive Dysfunction, Electroencephalography
- Trial name
- NCT05688449
- Testing
- Bupivacaine-fentanyl, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bezmialem Vakif University
Delirium
Electroencephalography Guidance of Anesthesia
This study aims to determine whether, compared with usual anesthetic care, an electroencephalography-guided anesthesia protocol is effective at preventing postoperative delirium and its downstream effects, and improving…
- Trial name
- ENGAGES (NCT02241655)
- Testing
- a pragmatic EEG-guided anesthetic protocol
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Washington University School of Medicine
Coronary Syndrome, Pediatric
Cerebral Oxygenation and Burst Suppression
investigators want to observe a group of pediatric patients who are going to undergo open thoracic surgery at Queen Silvia's child and youth hospital, Sahlgrenska University Hospital.
- Trial name
- NCT04206683
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Göteborg University
Endoscopy of Stomach (Procedure), Colonoscopy (Procedure)
EEG During Gastroscopy and/or Colonoscopy
During anesthesia, EEG shows specific and significant changes according to the depth of anesthesia and the drugs used. Endoscopic procedures like gastroscopies or colonoscopies are usually done on an outpatient basis using…
- Conditions
- Endoscopy of Stomach (Procedure), Colonoscopy (Procedure), Continuous Processed Electroencephalogram (Procedure)
- Trial name
- NCT07073274
- Testing
- EEG analysis
- Where
- Belgium
- Volunteers
- 149 people
- Sponsor
- Erasme University Hospital
Diabetes Mellitus, Geriatric
Burst Suppressions in Diabetic Elderly
This observational study aims to learn about the effects of diabetes mellitus in intraoperative electroencephalography (EEG) of elderly patients receiving general anesthesia.
- Conditions
- Diabetes Mellitus, Geriatric, General Anaesthesia, Electroencephalography
- Trial name
- NCT07037186
- Testing
- Electroencephalogram
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Burst Suppression, Anesthesia
Incidence of Slow Delta EEG Frequencies (0.1-1 Hz) Before Burst Suppression
The electroencephalogram (EEG) measures brain waves during general anaesthesia via an electrode placed on the forehead. These brain waves show the different stages of natural sleep as well as the state of the brain when a patient…
- Trial name
- SLOWWAVE (NCT07031427)
- Where
- 2 sites in Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Traumatic Brain Injury, Subarachnoid Hemorrhage
Comparison of Narcotrend and Cerebral Function Analysing Monitor in Intensive Care to Monitor Seizures and Deep Sedation
A study in the use of the Narcotrend depth of anaesthesia monitor to record a) seizures, and b) monitor a level of sedation referred to as 'burst suppression', in sedated patients in the adult and paediatric intensive care.
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Haemorrhage, Encephalitis
- Trial name
- NCT06067750
- Testing
- Narcotrend compared to Cerebral Function Analysing Monitor (CFAM)
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Nottingham University Hospitals NHS Trust