Clinical trials: CAD/CAM, open to volunteers
Indirect Tooth-colored Onlay Restorations in Posterior Teeth, Clinical Performance of Cervical-margin-relocated Onlay Restorations
Clinical Evaluation of Indirect Tooth-Colored Onlays With Cervical Margin Relocation
This study will evaluate the performance of three different tooth-colored onlay materials in adult patients' posterior teeth. First, investigators will use a bulk-fill composite resin to raise the cavity margin above the gum line…
- Trial name
- NCT07157410
- Testing
- Machinable lithium-disilicate ceramic onlay (IPS e.max CAD), Pressed lithium-disilicate ceramic onlay (IPS e.max Press), Machinable composite onlay (BRILLIANT Crios)
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Wear, Occlusal
Evaluation of Wear Resistance of CAD/CAM Hybrid Ceramic and Nano-Hybrid Composite Overlays in Endodontically Treated Molars and Their Effect on Natural Antagonist Teeth
This randomized clinical trial aims to to evaluate and compare the 24-month surface wear of the restoration and the surface wear of the opposing natural tooth structure of CAD/CAM Hybrid Ceramic (SHOFU Hard blocks) versus…
- Trial name
- NCT07689032
- Testing
- SHOFU Hard blocks, BRILLIANT Crios
- Volunteers
- 24 people
- Sponsor
- Cairo University
Partially Edentulous Mandible
Artificial Intelligence Assisted Workflow Versus Conventional Workflow in Guided Implant Placement
The AI assisted CAD/CAM workflow will be adopted for the treatment planning and guide design generation with the aim of comparing precision of implant placement with conventional digital workflow.
- Trial name
- Implant (NCT07523815)
- Testing
- AI assisted implant placement, Conventional computer guided implant placement
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sandra Moussa Botros El Tarzi
CAD/CAM, 3D-printed
Clinical Evaluation of 3D-Printed Resin Versus CAD/CAM-Milled Lithium Disilicate Overlay Restorations
The aim of this study is to clinically evaluate the performance of 3D-printed resin and CAD/CAM lithium disilicate overlay restorations.
- Conditions
- CAD/CAM, 3D-printed, Lithium Disilicate, Overlay Restorations
- Trial name
- NCT07853118
- Testing
- 3D-printed ODYX-CR ceramic-filled resin, CAD/CAM-milled lithium disilicate ceramic
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Endodontically Treated Teeth
Milled vs 3D-Printed Partial-Coverage Restorations in Endodontically Treated Molars
The goal of this clinical trial is to compare the clinical performance of Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM)-milled and 3D-printed composite resin partial-coverage restorations in endodontically…
- Trial name
- NCT07643311
- Testing
- Milled Composite Resin Onlay/Overlay Restoration, 3D-Printed Composite Resin Onlay/Overlay Restoration
- Where
- Chile
- Volunteers
- 142 people
- Sponsor
- Hospital San Jose
Tooth Loss
Ti-Mesh Frame Comparison for Alveolar Bone Augmentation
This research compares a chairside Titanium Mesh frame fabrication used during bone grafting procedures with the use of a computer-aided design/computer-assisted manufacture (CAD-CAM) Titanium Mesh frame.
- Trial name
- NCT06077513
- Testing
- CAD-CAM designed and preprinted Ti-Mesh frame, Conventional chairside fabrication of Ti-Mesh frame
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston University
Maxillary Diseases
Patient Satisfaction & Abutment Teeth Health in Maxillectomy Patients
randomized controlled trial in maxillectomy patients with two types of obturators with different manufacturing techniques
- Trial name
- NCT06934551
- Testing
- obturator
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
CAD-CAM, Patients Specific Manufacturing
Analysis of Mandibular Proximal Segment Position Using Virtual Orthognathic Surgical Planning, Individualized Guides, and Osteosynthesis Plates
Orthognathic surgery is a surgical procedure performed to correct dentofacial deformities. In recent years, with the use of virtual surgical planning, cutting guides, and patient-specific osteosynthesis plates, highly predictable…
- Conditions
- CAD-CAM, Patients Specific Manufacturing, Osteotomy, Sagittal Split Ramus
- Trial name
- NCT06442787
- Testing
- conventional splints, cutting guides and positioning guides, cutting guides and fixation plates
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Complete Edentulism, Maxillary Complete Denture Rehabilitation
3D Printing Orientation and Film Thickness for Maxillary Complete Dentures
This randomized crossover clinical trial aims to evaluate the effect of different three-dimensional (3D) printing orientations and layer thicknesses on the trueness, dimensional accuracy, and patient satisfaction of maxillary…
- Conditions
- Complete Edentulism, Maxillary Complete Denture Rehabilitation, Prosthodontics, 3d Printing
- Trial name
- NCT07740278
- Testing
- 0° 3D-Printed Maxillary Complete Denture, 45° 3D-Printed Maxillary Complete Denture, 90° 3D-Printed Maxillary Complete Denture
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tanta University
Denture, CAD/CAM
Effect of Certain Denture Disinfectants on Surface Topography, Microhardness and Dimensional Stability of CAD/CAM Milled Polymethyl Methacrylate and Polyether Ether Ketone Denture Base Materials
This study aims to evaluate and compare the influence of different denture cleansing methods using 1% sodium hypochlorite solution, 0.2% chlorhexidine solution and effervescent alkaline peroxide tablet solution -according to…
- Conditions
- Denture, CAD/CAM, Stability, PEEK
- Trial name
- NCT07672847
- Testing
- M0 group, M1 group : PMMA+ Sodium hypochlorite, M2 group: PMMA+ Chlorhexidine
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Menoufia University
Foot Deformities, Orthotic Device
Custom CAD/CAM Insoles for Plantar Pressure Improvement in Foot Deformities
This randomized controlled trial will investigate the effects of custom CAD/CAM insoles on plantar pressure distribution and gait parameters in individuals with foot deformities, such as pes planus, pes cavus, and hallux valgus.
- Conditions
- Foot Deformities, Orthotic Device, 3D Printing, CAD
- Trial name
- NCT07136649
- Testing
- Custom CAD/CAM Insoles
- Volunteers
- 30 people
- Sponsor
- Fenerbahce University
Tooth Discoloration, Tooth Staining
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without…
- Trial name
- NCT07464197
- Testing
- Customized bleaching tray fabrication, Reservoir tray design, Carbamide peroxide 10%
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Endodontically Treated Teeth, Indirect Restoration
Clinical Performance of Printed Hybrid Resin in Indirect Restorations
This randomized clinical trial aims to evaluate the clinical performance of a 3D-printed hybrid resin (VarseoSmile TriniQ) used for indirect restorations in endodontically treated teeth, compared with a CAD/CAM composite block…
- Trial name
- NCT07465978
- Testing
- Indirect adhesive overlay restoration, Enamel Plus HRi, RelyX Universal
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universitat Internacional de Catalunya
Deep Caries Lesion of Pemanent Teeth
Adjustment Period for Partial Crowns
The aim of this study is to compare the occlusal accuracy of CAD/CAM milled and 3D printed crowns guided by an occlusal device, starting from the same digital CAD design.
- Trial name
- Adjustment per (NCT07051590)
- Testing
- cad cam, 3D printer
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ceren Sire
Malformed Tooth
Clinical Evaluation of CAD/CAM vs. Conventional Veneer Restorations
The aim of the study is to clinically evaluate tooth-supported veneer restorations fabricated using the CAD/CAM process in comparison to conventionally manufactured pressed veneers on anterior teeth and to assess their long-term…
- Trial name
- NCT06969911
- Testing
- Laminate veneer CAD/CAM, Laminate Veneer Convetional
- Volunteers
- 40 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Dental Disorders Hard Tissues of Teeth, Dental Diseases
Clinical Evaluation of Full Contour Zirconia Chairside CAD/CAM Crowns
This investigation will be a randomized, prospective, longitudinal clinical trial to study the clinical performance of a new monolithic, zirconia material with shade, translucency and material graduation for chairside CAD/CAM…
- Trial name
- NCT06173167
- Testing
- Crowns self-adhesively luted, Crowns conventionally cemented
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG
CAD/CAM Space Maintainer, 3D Printing
Evaluation of Clinical Wear and Surface Roughness of Partial Restorations Produced by Additive and Subtractive Manufacturing Methods: A Split-Mouth Randomized Controlled Clinical Trial
The aim of this study is to compare the surface roughness and wear values of crowns fabricated using currently utilized 3D printing and CAD-CAM technologies.
- Conditions
- CAD/CAM Space Maintainer, 3D Printing, Dental Treatment, Dental Disease
- Trial name
- NCT07057401
- Testing
- CAD-CAM Manufactured Crowns, 3D Printed Crowns
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Husna Selinay
Complete Edentulism
Implementation of Digital Workflow for Complete Dentures - A Crossover Study
With a demographically ageing population and increasing patients with missing teeth, the demands on the healthcare system are set to further increase.
- Trial name
- NCT06457321
- Testing
- Sequence in receiving the fabricated dentures made using the conventional and partial digital method
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Dental Centre, Singapore
Badly Decayed Molars
Clinical Evaluation of 3D Printed Versus CAD/CAM Milled Onlays
The digital workflow in dentistry has proven in the past decades to be a time-efficient, multifunctional, effortless, and accessible approach.
- Trial name
- NCT06774560
- Testing
- CAD/Cam milled onlays, 3D printed onlays
- Volunteers
- 50 people
- Sponsor
- Cairo University
Maxillary Sinus, Allograft
Maxillary Sinus Augmentation Using CAD/CAM Allogenic Bone Blocks Versus Particulate Allogenic Grafts
28 patients will be included in this study with atrophic posterior maxillary ridge due to sinus pneumatization who will randomly assigned to two groups Group I: sinus lifting using CAD/CAM allogenic block through lateral window…
- Trial name
- NCT07604155
- Testing
- sinus lifting using CAD/CAM allogenic block, sinus lifting using particulate allogenic graft
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Tanta University