Clinical trials: CAD-CAM
Edentulous Mouth
Retention of Computer Aided Design and Computer Aided Manufacturing Titanium Versus Co/Cr Single Dentures.
Steps in short: Undergoing the conventional steps of maxillary single denture construction till the step of framework construction that will be designed and constructed using CAD/CAM after optical scanning of the master cast ( 2…
- Trial name
- NCT03675594
- Testing
- CAD/CAM titanium denture base, CAD/CAM cobalt/chromium denture bases
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Single Tooth Lost
Posterior CAD/CAM Cobalt-chromium Alloy Single Crowns: 4-year Prospective Clinical Study
Objectives - To evaluate the 4-year clinical outcomes of ceramic veneered Computer Aided Design/Computer Aided Manufacturing (CAD/CAM) Co-Cr single crowns supported by natural teeth in posterior regions.
- Trial name
- NCT02956174
- Testing
- Co-Cr single crown, Periodontal parameters
- Volunteers
- 89 people
- Sponsor
- Federico II University
Dental Caries
Investigation of the Effect of Deep Margin Elevation Technique on the Clinical Performance of Endocrown Restorations Produced by Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) System
The aim of this clinical study is to investigate the impact of the deep margin elevation technique on the clinical performance of CAD/CAM endocrown restorations in deep Class II cavities.
- Trial name
- NCT06222918
- Testing
- Deep Margin Elevation (G-ænial Universal Injectable)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Tooth Decay
Comparing the Clinical Success of Two Different CAD/CAM Full Cuspal Coverage Onlays
This is a single-center, ten-year, randomized controlled, split-mouth clinical trial. A total of 164 adult patients requiring full-cuspal coverage onlays will be enrolled.
- Trial name
- CUSTOM (NCT07519382)
- Testing
- full cuspal covarage onlay
- Where
- Hungary
- Volunteers
- 164 people
- Sponsor
- Semmelweis University
Edentulous Mandible
Radiographic and Clinical Evaluations of Mandibular Implant-Supported Overdentures Supported by Conventional and Zirconia CAD/CAM Bars: A Randomized Clinical Trial
This randomized clinical trial aimed to evaluate the radiographic and clinical evaluations of mandibular implant-supported overdentures supported d by two different bar materials。 Completely edentulous patients received two…
- Trial name
- NCT07429149
- Testing
- Cobalt-Chromium Bar Attachment, Zirconia CAD/CAM Bar Attachment
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sara Mohamed Fakhry Meligy Mohamed
Tooth Wear
Survival and Success of CAD/CAM Restorations After 5 Years of Intraoral Use
This study evaluates the survival and success rates of dental restorations fabricated exclusively using CAD/CAM technology over a period of 5 years.
- Trial name
- NCT07276269
- Testing
- CAD/CAM Digital Restoration Placement, Study of the Survival and Success of Endodontic Posts Using the CAD/CAM Digital Method After 5 Years of Intraoral Use
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Resin Cement
Evaluation of Marginal Integrity Using Bioactive Cement Incementation of Indirect Composite Blocks
The aim of this study is to evaluate of marginal integrity of indirect composite restoration after cementation by a bioactive cement in comparison to dual cure resin cement using Modified USPHS criteria
- Trial name
- NCT04557657
- Testing
- Active bio Activa, Resin Cement
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontically Treated Teeth
Milled vs 3D-Printed Partial-Coverage Restorations in Endodontically Treated Molars
The goal of this clinical trial is to compare the clinical performance of Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM)-milled and 3D-printed composite resin partial-coverage restorations in endodontically…
- Trial name
- NCT07643311
- Testing
- Milled Composite Resin Onlay/Overlay Restoration, 3D-Printed Composite Resin Onlay/Overlay Restoration
- Where
- Chile
- Volunteers
- 142 people
- Sponsor
- Hospital San Jose
Coronary Artery Disease (CAD)
Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel (TRIGGER-PCI)
To determine the efficacy of prasugrel versus clopidogrel for the reduction of adverse cardiovascular outcomes in patients with high platelet reactivity on clopidogrel after successful implantation of coronary drug-eluting…
- Trial name
- TRIGGER-PCI (NCT00910299)
- Testing
- Prasugrel, Clopidogrel
- Where
- 27 sites in United States, Germany
- Volunteers
- 423 people
- Sponsor
- Eli Lilly and Company
Implant Site Reaction
Peri-implant Soft Tissue Conditioning of Immediate Posterior Implants by CAD/CAM Socket Sealing Abutments
One of the major challenges one clinician can face while performing immediate placement on posterior area, is the ability of obtaining a hermetic primary closure of the soft tissue.
- Trial name
- NCT05276765
- Testing
- cad/cam socket sealing abutment, standard healing abutment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Partial Coverage Restoration
Clinical Outcomes of Zirconia-reinforced Lithium Silicate Partial Coverage Crowns Compared to Lithium Disilicate Partial Coverage Crowns
The purpose of this randomized controlled clinical trial is to evaluate the clinical outcomes of Partial Coverage Restorations fabricated with zirconia-reinforced lithium silicate ceramic system compared to partial coverage…
- Trial name
- NCT02861729
- Testing
- Vita Suprinity, IPS e.max
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Joint Ankylosis
Patient-Specific Guides for Gap Pediatric Arthroplasty
To date, few reports have combined patient-specific guides with piezoelectric devices for gap arthroplasty in children. This study evaluates the feasibility, accuracy, and early outcomes of this approach, hypothesizing that the…
- Trial name
- NCT07320911
- Testing
- Patient-Specific Narrow-Slit Osteotomy Guides
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Alexandria University
Edentulous
All-On-4® Treatment Concept
Indication : edentulous patients To evaluate and compare the marginal bone level change around tilted and straight NobelActive implants placed in healed sites with All-on-4-treatment concept after immediate function supporting…
- Trial name
- NCT02186912
- Testing
- Nobel Active, Nobel Procera IBO
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nobel Biocare
Edentulous Jaw
PEEK Bar Versus Titanium Bar Fabricated by CAD-CAM in Mandibular Hybrid Prostheses: A Comparative Study
CAD/CAM-fabricated PEEK bar exhibited greater dimensional deviation in comparison to its titanium counterpart. Nevertheless, patients with PEEK bars reported higher satisfaction levels and lower marginal bone loss when compared…
- Trial name
- NCT06201169
- Testing
- implant placement
- Where
- 2 sites in Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Amr Azab Abd El-Fattah
Palatal Expansion Technique
Evaluation of Hard and Soft Tissue Change During Maxillary Expansion Using a Computer-aided Design / Computer-aided Manufacturing Appliance.
Hard tissue changes during the transversal expansion of the maxilla using a CAD/CAM expansion appliance. Soft tissue changes during the transversal expansion of the maxilla using a CAD/CAM expansion appliance.
- Trial name
- NCT06246656
- Testing
- Maxillary Expansion
- Where
- Austria
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Edentulism
Comparing Cobalt-Chromium Versus PEEK Secondary Telescopic Crowns on Implant Retained Mandibular Overdenture.
The aim of this randomized clinical trial was to compare I- The clinical behavior of implant retained removable overdenture using telescopic retention system fabricated using CAD\CAM techniques where the effects of the different…
- Trial name
- NCT06637930
- Testing
- Edentulous Alveolar Ridge In Mandible
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Amr El Sayed Khalifa
Complete Edentulism, Maxillary Complete Denture Rehabilitation
3D Printing Orientation and Film Thickness for Maxillary Complete Dentures
This randomized crossover clinical trial aims to evaluate the effect of different three-dimensional (3D) printing orientations and layer thicknesses on the trueness, dimensional accuracy, and patient satisfaction of maxillary…
- Conditions
- Complete Edentulism, Maxillary Complete Denture Rehabilitation, Prosthodontics, 3d Printing
- Trial name
- NCT07740278
- Testing
- 0° 3D-Printed Maxillary Complete Denture, 45° 3D-Printed Maxillary Complete Denture, 90° 3D-Printed Maxillary Complete Denture
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tanta University
Molar Hypomineralization, Dental Restoration Failure of Marginal Integrity
CAD-CAM or Adhesive Approaches for MIH Treatment
Aim: This randomized controlled clinical study aimed to compare direct composite resin restorations and Computer Aided Design-Computer Aided Manufacturing (CAD-CAM) supported inlay or onlay restorations in young permanent molar…
- Trial name
- NCT06456619
- Testing
- Tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Baskent University
Occlusal Analysis
Digital Workflow Versus Functional Pick-up Techniques of Two- Implant Retained Mandibular Overdentures
The goal of this clinical trial] is to learn if digital pick up can affect occlusal forces on teeth in completely edentulous patients restored with digital complete overdenturs.
- Trial name
- NCT06995547
- Testing
- implant overdenture
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Orthodontics
Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) - Based Planning and Creation of Orthodontic Appliances
In orthodontics, conventional fixed appliances, usually consisting of prefabricated components, require step-by-step adjustment in order to move teeth in the planned direction.
- Trial name
- NCT00871026
- Testing
- orthodontic treatment with customized archwires, orthodontic treatment with prefabricated archwires
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Charite University, Berlin, Germany