Clinical trials: CHD
Lupus Erythematosus, Systemic
Analyzing the Association of Gene Variants With Increased Risk of Coronary Heart Disease in Women With Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease that predominantly affects younger premenopausal women. The risk of coronary heat disease (CHD) in women with SLE is up to 50 times higher than in the general…
- Trial name
- NCT00563082
- Volunteers
- 1,254 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Congenital Heart Disease, Congenital Heart Defect
Comparison of Home and Standard Clinic Monitoring of INR in Patients With CHD
Summary: Congenital heart disease (CHD) is the most prevalent form of birth defect with a global rate of 1.35 million newborns born with CHD annually.
- Conditions
- Congenital Heart Disease, Congenital Heart Defect, Adult Congenital Heart Disease
- Trial name
- NCT04136379
- Testing
- INR monitoring using a CoaguChek POC device
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Ulster
Coronary Heart Disease (CHD), Artifical Intelligence
Construction and Validation of a Coronary Artery Disease-Specific Large Language Model and Its Evaluation Framework (CorAI)
Coronary artery disease (CAD) affects an estimated 11.39 million people in China, and mortality has continued to rise since 2012.
- Trial name
- CorAI (NCT07766551)
- Testing
- No Intervention: Observational Cohort
- Where
- 3 sites in China
- Volunteers
- 640 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Heart Disease
Randomized Trial of Behavioral Intervention Versus Standard Treatment
The purpose of this study is to determine the possible preventive effect of behavioural modification versus standard treatment after hospital discharge in CHD patients.
- Trial name
- SUPRIM (NCT00888485)
- Testing
- Behavioral interventional program
- Volunteers
- 362 people
- Sponsor
- Uppsala University
Congenital Disorders
Percutaneous Interventions in Adults With CHD
The primary objective of this study is to determine the clinical benefits of percutaneous intervention to improve pulmonary blood flow on oxygen saturations, symptoms, exercise tolerance and hematocrit in patients with complex…
- Trial name
- NCT00266916
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Children's Healthcare of Atlanta
Coronary Heart Disease
Study of Herbal Formula Corresponding to Syndrome in Treating Post Percutaneous Coronary Intervention (PCI) Patients With Coronary Heart Disease (CHD)
We conduct this clinical trial to determine the effects of Xuefu Zhuyu capsule (based on TCM "Zheng Hou" theory) in helping recovery from coronary heart disease(CHD)after PCI and find out whether this kind of effecacy is much…
- Trial name
- NCT00817024
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Congenital Heart Disease, Brain Injuries
Autologous Umbilical Cord Blood Treatment of Neonate With CHD
The aim of the study is to evaluate the feasibility and safety and efficacy of collecting and infusing autologous umbilical cord blood (UCB) in newborn infants with hypoplastic left heart syndrome (HLHS) and transposition of…
- Conditions
- Congenital Heart Disease, Brain Injuries, Low Cardiac Output Syndrome, Neonatal Disorder
- Trial name
- NCT03558269
- Testing
- Autlogous UCB infusion
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Congenital Heart Disease
The Co-Op @ HeartWorks
This protocol is a research study involving human subjects diagnosed with Congenital Heart Defects/Disease (CHD). The Co-Op @ HeartWorks is a cooperative between the research platform at HeartWorks and members of the CHD…
- Trial name
- NCT06469918
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- HeartWorks, Inc.
Coronary Artery Disease
Risk Factors Promoting Coronary Plaque Progression In China
Coronary drug-eluting stent (DES) has been launched in China for more than ten years. Although it effectively decreases the overall incidence of re-stenosis, DES cannot inhibit the progression of atherosclerosis plaque outside…
- Trial name
- RIPPER (NCT02692014)
- Where
- China
- Volunteers
- 2,400 people
- Sponsor
- Zhang Qi, MD
Dysphagia of Newborn
Evaluating Dysphagia in Neonates With CHD
The overall goal of this study is to describe the oral motor skills of neonates born with congenital heart defects, both before and after cardiac surgery, and to evaluate current measures of feeding motor skills and feeding…
- Trial name
- NCT03045757
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Breast Cancer
10 Year Coronary Heart Disease (CHD) Risk Evaluation and Its Treatment Pattern Analysis in Postmenopausal Early Breast Cancer (EBC) Patients Taking Aromatase Inhibitors (AI)
10-year CHD risk evaluation and its treatment pattern analysis in postmenopausal early breast cancer patients taking aromatase inhibitors.
- Trial name
- NCT00885612
- Where
- 27 sites in South Korea
- Volunteers
- 1,114 people
- Sponsor
- AstraZeneca
Coronary Disease, Cardiovascular Diseases
Dietary Fatty Acids, PPAR Activated Genes, and CHD
To examine the relationship between genetic and dietary factors that modify the risk of coronary heart disease (CHD).
- Conditions
- Coronary Disease, Cardiovascular Diseases, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00071019
- Volunteers
- 4,547 people
- Sponsor
- Harvard School of Public Health (HSPH)
ADHD, ASD
Cognitive Rehabilitation (Mega Team) and Its Effects on Emotional and Behavioral Regulation in ADHD, ASD, and CHD
Children with disorders that impact neurodevelopment often have difficulties with executive functions and regulating emotions. Cognitive-based video game training has been shown to improve outcomes, however, this training has…
- Conditions
- ADHD, ASD, CHD - Congenital Heart Disease
- Trial name
- NCT03502239
- Testing
- Mega Team - video game
- Where
- Canada
- Volunteers
- 440 people
- Sponsor
- The Hospital for Sick Children
Tetralogy of Fallot
Reoxygenation for Cyanotic Pediatric CHD
Evidence is emerging that those patients with cyanotic pathologies may be more vulnerable to end-organ injury during and after surgery than those patients without, because of compromised cardiopulmonary performances or the…
- Trial name
- Reoxygenation (NCT03568357)
- Testing
- Reoxygenation
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Patient Satisfaction, Patient Preference
Pharmacist Follow-up, a Qualitative Study of Patient Experience
A pharmacist follow-up procedure is under development. Patients with coronary heart disease (CHD) is being followed up by a pharmacist for one year with three meetings; at discharge from hospital, after three months and after one…
- Trial name
- NCT01131715
- Where
- Norway
- Volunteers
- 4 people
- Sponsor
- Hospital Pharmacy of North Norway Trust
Liver Injury, Hepatitis B Virus Infection History
Liver Injury by Statins in Patients With History of Hepatitis B Virus Infection
The purpose of this study is to investigate the incidence of liver injury by statins in coronary heart disease (CHD) patients with history of hepatitis B virus (HBV) infection.
- Trial name
- LISHBV (NCT02808299)
- Testing
- HBV infection history
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cardiovascular Disease
Predictive Value of Coronary Heart Disease (CHD) Biomarkers for CHD Death
The overall objective of this research proposal is to determine whether the predictive value of using plasma concentrations of selected nutrient biomarkers of food intake determined using a single plasma sample either alone or in…
- Trial name
- WHI (NCT01864122)
- Where
- United States
- Volunteers
- 2,448 people, healthy volunteers welcome
- Sponsor
- Tufts University
Congenital Heart Disease (CHD)
Physical Rehabilitation in Patients With Complex Congenital Heart Disease
Studies have shown that patients with congenital heart disease have functional changes compared to healthy individuals. Several interventions can be performed to minimize these changes; physical rehabilitation is one of these…
- Trial name
- Rehabkids (NCT07089264)
- Testing
- Physical rehabilitation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital do Coracao
Coronary Heart Disease
Safety and Efficacy of DCB Therapy for de Novo Lesions Under the Guidance of QFR in CHD Patients (UNIQUE-DCB-I Study )
Since Gruntzig successfully performed percutaneous coronary balloon angioplasty in 1977, percutaneous coronary intervention has developed rapidly.
- Trial name
- NCT04104854
- Testing
- drug coated balloon
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Coronary Artery Disease
Comparison of DCB and DES for Severe Calcification of de Novo Lesion in Elderly CHD
The goal of this clinical trial was to compare the effectiveness of drug balloons versus drug-coated stents in calcified lesions in elderly coronary artery disease.
- Trial name
- NCT05750771
- Testing
- DES, DCB
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology