Clinical trials: CONTROL Condition
Pain, Acute
Comparison of Morphine With Nalbuphine in a Multimodal Approach for Pain Relief in Patients Undergoing Gynecological Procedures: Randomized Controlled Double Blind Clinical Trial
This study was conducted in the Aga Khan University Hospital, Karachi. Pakistan is developing country and overall shortage of Morphine in developing country.
- Trial name
- NCT06191770
- Testing
- Morphine,
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Aga Khan University Hospital, Pakistan
Premenstrual Syndrome
The Effect of Mandala Art Therapy in Coping With Premenstrual Syndrome
Mandala practice will be applied to women with premenstrual syndrome. The intervention group (Mandala practice group) and the control group each consisted of 60 women.
- Trial name
- NCT06144073
- Testing
- Intervention (Mandala art therapy) group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Chronic Pain
"Evaluation of the Efficacy of Intravenous Lidocaine on Chronic Post-operative Pain in Patients Requiring Emergency Abdominal Surgery. A Multicentre, Randomised, Controlled, Double-blind Study."
Chronic pain is a major public health issue. According to the most recent sources, it affects around 11 million people in France, leading to a significant deterioration in patients' quality of life, limitations in their…
- Trial name
- LIDOC-POPEYE (NCT07869173)
- Testing
- Lidocain
- Where
- 6 sites in France
- Volunteers
- 266 people
- Sponsor
- Nantes University Hospital
Incisional Hernia of Anterior Abdominal Wall
Study on the Efficacy of Prophylactic on Lay Mesh in Preventing Post-operative Hernia in Liver Transplant Patients
Study Design: Single-blinded, randomized, prospective clinical trial. Study Population: End-stage liver disease patients' candidates for liver transplantation.
- Trial name
- NCT04512469
- Testing
- Low molecular weight mesh
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obesity, Morbid
Body Composition Optimization Intervention RCT
This study aims to identify if the addition of structured nutrition/weight loss counseling to patients at the bariatric clinic can increase the conversion from bariatric clinic to surgical candidacy from (the current) 11% to a…
- Trial name
- NCT05993169
- Testing
- Body Composition optimization visits
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Jacob M. Elkins
Primary Insomnia
Sleep Laboratory Study to Investigate the Safety and Efficacy of Neu-P11 in Primary Insomnia Patients
This is a phase II study. It is conducted using a randomized, double-blind, 3-arm placebo controlled, parallel group design. Eligible patients will be randomized in a 1:1:1 ratio to receive Neu-P11 20 mg, Neu-P11 50 mg or placebo…
- Trial name
- NCT01489969
- Testing
- Neu-P11
- Where
- 9 sites in United States
- Volunteers
- 137 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Bipolar Disorder, Attention Deficit Hyperactivity Disorder
Aripiprazole Associated With Methylphenidate in Children and Adolescents With Bipolar Disorder and ADHD
There is a scarcity of clinical trials assessing the effects of medications in children with bipolar disorder. This study aims to assess the efficacy of Aripiprazole associated with Methylphenidate (MPH)for the treatment of…
- Trial name
- NCT00305370
- Testing
- Aripiprazole
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Rio Grande do Sul
Friedreich Ataxia
Efficacy Study of Epoetin Alfa in Friedreich Ataxia
Friedreich's ataxia (FRDA) is a rare genetic disorder characterised by severe neurological disability and cardiomyopathy. Friedreich's ataxia is the consequence of frataxin deficiency.
- Trial name
- FRIEMAX (NCT01493973)
- Testing
- Epoetin alfa
- Where
- 3 sites in Italy
- Volunteers
- 56 people
- Sponsor
- Federico II University
Obesity, Lipid Disorders
A Clinical Study to Evaluate the Safety,Tolerability and PK of ZYT1, Following Oral Administration in Healthy Volunteers
This is a clinical study to evaluate the safety, tolerability and pharmacokinetics of ZYT1, following oral administrations in healthy volunteers. The study shall be divided into four plans as given below: 1.
- Trial name
- NCT01543269
- Testing
- ZYT1
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zydus Lifesciences Limited
Breast Cancer
Efficacy of Exercise Using Connected Activity Trackers and Therapeutic Education in Localized Breast Cancer
The 3-year DISCO study aims to systematically implement physical activity in breast cancer patients. The primary objective is to investigate the efficacy of a connected device (personalized non-supervised exercise program…
- Trial name
- DISCO (NCT03529383)
- Testing
- Connected device, Therapeutic education
- Where
- 3 sites in France
- Volunteers
- 436 people
- Sponsor
- Centre Leon Berard
Colonic Diseases, Functional
Combination Herbal Therapy (CHT) Versus Placebo in Patients With Irritable Bowel Syndrome (IBS)
This is an 8-week double-blind, placebo-controlled, randomized, parallel-group study with an additional two week baseline observation period to evaluate the safety of combination herbal therapy (CHT) versus placebo and short and…
- Trial name
- NCT00130741
- Testing
- CHT - herbal therapy
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Positive Communication (Primary), Negative Communication
Psychological Context Effects
This study explores how contextual effects in the fore of positive and negative communication can affect the effect of an osteopathic technique on pain pressure thresholds.
- Conditions
- Positive Communication (Primary), Negative Communication, Control Condition
- Trial name
- NCT03855254
- Testing
- communication type
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Swansea University
Substance Use Disorders, Contingency Management
Effectiveness of Contingency Management in the Treatment of Crack Addiction in Brazil
Crack addiction has become a severe public health problem in Brazil. Crack users present elevated prevalence rates of psychiatric comorbidities, sexual transmitted infections and unemployment with high probability of living or…
- Conditions
- Substance Use Disorders, Contingency Management, Addiction, Cocaine
- Trial name
- NCT03345394
- Testing
- Contingency Management, Standard treatment
- Where
- Brazil
- Volunteers
- 98 people
- Sponsor
- Federal University of São Paulo
Pediatric ALL, Cancer
A Phase II Randomized Controlled Trial to Determine the Efficacy of an auGmented reAlity gaMe in pediatrIc caNcer Patients Who Are Opioid Naïve Undergoing Surgery to Reduce Postoperative Opioid Use (GAMING-ON Study)
To learn if playing an augmented reality game called SpellBound can reduce pain and the need for opioids in young patients scheduled for surgery.
- Trial name
- NCT05466994
- Testing
- IPAD, Augmented Reality
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- M.D. Anderson Cancer Center
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Comparison of INRECSURE and LISA in Preterm Neonates With RDS
The primary hypothesis of this study is that surfactant administration by INtubate-RECruit-SURfactant-Extubate (IN-REC-SUR-E), via a high frequency oscillatory ventilation recruitment maneuver increases survival without BPD at 36…
- Trial name
- INRECLISA (NCT05711966)
- Testing
- Ventilator for High-frequency Oscillatory Ventilation (HFOV), Less invasive surfactant administration (LISA)
- Where
- Italy
- Volunteers
- 381 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Atopic Dermatitis
A Phase 2b Dose-Ranging Study to Evaluate the Efficacy and Safety of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis
This double-blind, placebo-controlled study is designed to evaluate the safety and efficacy of ENV-294 in adults with moderate-to-severe atopic dermatitis (AD).
- Trial name
- NCT07643766
- Testing
- ENV-294
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Enveda Therapeutics
Cervical Intraepithelial Neoplasia, Cervical Cancer
Efficacy, Immunogenicity and Safety Study of Recombinant Human Papillomavirus Vaccine(6,11,16,18,31,33,45,52,58 Type)(E.Coli)
This phase III clinical study was designed to evaluate the efficacy,immunogenicity and safety of Recombinant Human Papillomavirus Vaccine (6,11,16,18,31,33,45,52,58 Type)(E.Coli) manufactured by Xiamen Innovax Biotech CO., LTD.…
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Condylomata Acuminata
- Trial name
- NCT04537156
- Testing
- Nonavalent HPV vaccine, Bivalent HPV vaccine
- Where
- 2 sites in China
- Volunteers
- 9,327 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Diabetic Foot Ulcer, Skin Lesions
Allogeneic Platelet Rich Plasma (PRP) to Treat Diabetic Foot Ulcers
Chronic skin ulcers pose a major health burden because of population aging and increased prevalence of chronic diseases such as diabetes.
- Conditions
- Diabetic Foot Ulcer, Skin Lesions, Allogeneic, PRP
- Trial name
- NCT06680856
- Testing
- PRP+HA, HA
- Where
- 2 sites in Italy
- Volunteers
- 72 people
- Sponsor
- Ospedale Policlinico San Martino
Type 2 Diabetes
An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release Tablets
The purpose of this clinical research study is to learn if initiating treatment with BMS-51248 (Dapagliflozin) in combination with metformin XR can improve diabetes control in patients with Type 2 Diabetes who do not receive any…
- Trial name
- NCT00643851
- Testing
- Dapagliflozin, Metformin XR
- Where
- 99 sites in United States, Mexico and 5 more
- Volunteers
- 994 people
- Sponsor
- AstraZeneca
Chronic Disease
Effect of Music Therapy on Hospital Anxiety/Depression and Comfort Level
Aim: It has been determined that there are limited studies in our country where music is used as a nursing intervention and the effects of music therapy on the psychological symptoms and comfort levels of individuals with chronic…
- Trial name
- NCT06865729
- Testing
- Music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Amasya University
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