Clinical trials: COPD
Pulmonary Disease, Chronic Obstructive
The Nasal Airway in Chronic Obstructive Pulmonary Disease
The study is based on the theory of a "unified airway" that considers the nose and paranasal sinuses together with lower airways as one integrated unit.
- Trial name
- COPD (NCT02826954)
- Testing
- Upper airway assessment, including nasal biopsy
- Where
- Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Chronic Obstructive Pulmonary Disease, Lung Cancer
COPD Care Pathway Among Patients With Cancer
This study gathers information for the development of a COPD care pathway for patients with cancer that reduces the treatment burden of patients, implements critical components of COPD care, and overcomes common barriers to COPD…
- Conditions
- Chronic Obstructive Pulmonary Disease, Lung Cancer, Head and Neck Cancer
- Trial name
- NCT05984680
- Testing
- Observational Phase 1, Observational Phase 2, Group I, Observational Phase 2, Group II
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Orthopedic Disorder, Neurologic Disorder
Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions
To determine the safety and efficacy of Amniotic and Umbilical Cord Tissue for the treatment of the following condition categories: Orthopedic, Neurologic, Urologic, Autoimmune, Renal, Cardiac and Pulmonary Conditions.
- Conditions
- Orthopedic Disorder, Neurologic Disorder, Urologic Diseases, Erectile Dysfunction
- Trial name
- NCT03899298
- Testing
- Amniotic and Umbilical Cord Tissue Procedure
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- R3 Stem Cell
Asthma, COPD
A Bioequivalence Pivotal Study of SYN010 HFA Inhaler and Symbicort® 160/4.5 in Healthy Volunteers Without Charcoal Block
The objective of this pivotal study is to evaluate the relative bioavailability of SYN010 HFA Inhaler and Symbicort 160/4.5μg in healthy volunteers without charcoal block.
- Trial name
- NCT04494321
- Testing
- Budesonide, Formoterol
- Where
- Taiwan
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Intech Biopharm Ltd.
Pulmonary Disease, Chronic Obstructive
Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of GSK573719 (LAMA) and GW642444 (LABA)Administered Individually and Concurrently in Healthy Japanese Subjects
GW642444 is a potent and selective long-acting beta2 agonist; GSK573719 is a long-acting, inhaled, muscarinic receptor antagonist (or anticholinergic) bronchodilator.
- Trial name
- DB2113208 (NCT00976144)
- Testing
- GSK573719
- Where
- Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Copd
Searching Clinical Chronic Obstructive Pulmonary Disease Onset
The aim of this study is to determine if presence of dyspnea identifies differences in the 6-min walk test performance among smokers with normal or mild spirometric obstruction, accounting for the confounding effect of heart…
- Trial name
- SOON (NCT03026439)
- Where
- Chile
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Respiratory System
Study to Characterize Lung Deposition, Pharmacokinetics, Safety and Tolerability of Single Inhalations of Radiolabeled Ciprofloxacin Dry Powder in Healthy Subjects and Patients With Chronic Lung Diseases
The purpose of this study is to characterize variability and extent of the deposition of ciprofloxacin in the respiratory tract of healthy subjects in comparison to patients with chronic lung diseases after inhalation of a single…
- Trial name
- NCT01538667
- Testing
- Ciprofloxacin (Cipro Inhale, BAYQ3939)
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
COPD
The Acute Cardiorespiratory Response to Blood-flow Restricted Versus Traditional Exercise Training Regimens (CaRe BFR)
The investigators hypothesize that BFR exercise regimens result in a different acute cardiorespiratory response pattern compared to traditional exercise regimens.
- Trial name
- CaRe-BFR (NCT05163600)
- Testing
- BFR-CYC 50% peak / 50% AOP (exhaustive), BFR-CYC 3x2min, BFR Resistance 80% LOP
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Asthma, Chronic Obstructive Pulmonary Disease
Trial Comparing Effect of He/O2 to Medical Air on Pulmonary Function Disease
This clinical trial will include healthy volunteers, COPD patients and asthmatic patients who will breathe He/O2 78:22, He/O2 65:35 and medical air consecutively in a randomised order.
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Healthy
- Trial name
- NCT00801307
- Testing
- spirometer
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Air Liquide SA
Asthma, Allergic Rhinitis
Study on the Influence of Climatic and Environmental Factors on Respiratory Diseases in Sanya, Hainan Province, China.
To investigate the Influence of Climatic and Environmental Factors on Respiratory or Allergic Diseases in Sanya.
- Conditions
- Asthma, Allergic Rhinitis, Chronic Obstructive Pulmonary Disease(COPD), Atopic Dermatitis
- Trial name
- NCT05330637
- Testing
- Climate and environment in Sanya
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Chronic Obstructive Pulmonary Disease (COPD)
Postural Control in Chronic Obstructive Pulmonary Disease
Postural control impairment is common in people with COPD (pwCOPD), which can increase the risk of falls and affect quality of life.
- Trial name
- NEUROTIGUE P (NCT06863246)
- Testing
- Evaluation of cognitive task on static balance, Evaluation of visual feedback on static balance
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms
GOLD Stage I Chronic Obstructive Pulmonary Disease (COPD)
Recently integrated in clinical practice, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification states that a mild (stage I) chronic obstructive pulmonary disease (COPD) is present, in a smoker, when…
- Conditions
- Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms, Physical Activity
- Trial name
- GOLD (NCT01360788)
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Laval University
COPD, Smoking
COPD Metabolome, Smoking Oxidants and Aberrant Ciliated Cell Function
Cigarette smoking is the major cause of chronic obstructive pulmonary disease (COPD), the 4th cause of mortality in the US. Central to COPD pathogenesis is "ciliopathy", dysfunction of the airway ciliated cells that mediate…
- Trial name
- NCT01974154
- Testing
- Cohort I, Cohort II
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pulmonary Disease, Chronic Obstructive
Effect of GSK1160724 In Healthy Volunteers
GSK1160724 is a potent mAChR antagonist, which is being developed for treatment of chronic obstructive pulmonary disease (COPD)
- Trial name
- NCT00555022
- Testing
- GSK1160724, Tiotropium bromide
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Evaluation the Safety of hemay005 Tablets
Explore the influence of different administration methods (titration/non-titration) of Hemay005 tablets on the incidence of adverse reactions.
- Trial name
- NCT06908642
- Testing
- Hemay005 tablet
- Where
- China
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- Anhui Hemay Pharmaceutical Co., Ltd
Chronic Obstructive Pulmonary Disease, Postural; Defect
An Investigation of the Cervical Region Biomechanics in Patients With Chronic Obstructive Pulmonary Disease
The aim of this study is to investigate cervical region biomechanics, muscle performance and respiratory muscle strength in patients with Chronic Obstructive Pulmonary Disease (COPD) compared to healthy subjects.
- Conditions
- Chronic Obstructive Pulmonary Disease, Postural; Defect, Cervical Pain, Cough
- Trial name
- NCT06246370
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cancer, Chronic Obstructive Pulmonary Disease
Does Continuous Vital Sign Monitoring Increase Investigations and Interventions in Complication-free Patients?
This aim of this study is to investigate whether active alerts during CVSM result in an increased number of diagnostic tests and treatments in complication free patients, hypothesizing that more interventions are performed in the…
- Conditions
- Cancer, Chronic Obstructive Pulmonary Disease, Surgery-Complications
- Trial name
- WARD-OT (NCT06361862)
- Testing
- Active alarms from WARD software
- Where
- Denmark
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COPD
Effect of Self Management Program on Clinical Status of COPD Patients
This study evaluates the effectiveness of self management programs based on 5A model on the lung function status, dyspnea and exercise tolerance in Chronic Obstructive Pulmonary Disease patients.
- Trial name
- NCT02567474
- Testing
- 5 A model
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ahvaz Jundishapur University of Medical Sciences
COPD
Effects of Breathing Exercises With and Without Inspiratory Muscle Training in COPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is a major health issue that affects a large proportion of the population, especially those over 50 years old. It is characterized by breathlessness and reduced lung function.
- Trial name
- NCT06555445
- Testing
- BREATHING EXERCISE, BREATHING EXERCISE REGIMEN COUPLED WITH BREATHER DEVICE
- Where
- Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease (COPD)
Artificial Intelligence-Based Motion Analysis for Early Detection of COPD
This study aims to develop a non-invasive and contact-free diagnostic system that uses artificial intelligence (AI) to detect Chronic Obstructive Pulmonary Disease (COPD) by analyzing walking patterns.
- Trial name
- NCT07010211
- Testing
- Gait Video Recording and Analysis
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Burcin Celik