Clinical trials: COVID19 Patients
Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Disease Stage 5 With Transplant
Vaccination Against COVID-19 in Chronic Kidney Disease
This is a prospective, multi-center, observational study that will enroll patients receiving dialysis (hemodialysis or peritoneal dialysis) or patients with kidney transplantation who will be vaccinated against COVID-19.
- Conditions
- Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Disease Stage 5 With Transplant, Vaccine Response Impaired
- Trial name
- NCT04743947
- Testing
- No intervention; observational study
- Where
- 5 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
COVID, SARS-CoV 2
COVID19 Clinical Predictors and Outcome
In December 2019, a novel coronavirus (SARS-CoV-2) emerged in Wuhan, Hubei, China, and now spreads across international borders.
- Trial name
- NCT04416347
- Testing
- SARS-CoV2 Infection
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- St George's University Hospitals NHS Foundation Trust
COVID-19
Recombinant Hyperimmune Polyclonal Antibody (GIGA-2050) in COVID-19 Patients
The purpose of this study is to evaluate the safety and tolerability of single ascending IV dose administrations of GIGA-2050 in patients hospitalized with COVID-19.
- Trial name
- NCT04883138
- Testing
- GIGA-2050
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- GigaGen, Inc.
Tracheostomy
Percutaneous Tracheostomy With COVID-19
Coronavirus disease 2019 (COVID-19) has brought about a requirement of intensive care and mechanical ventilation for a significant portion of patients.
- Trial name
- NCT04447638
- Testing
- Tracheostomy with aerosol box in COVID-19 positive patients
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Çanakkale Onsekiz Mart University
Coronavirus Infection
Clinical Evaluation of Cordio Application in Adult COVID-19 Virus Positive Patients
Study on adult patients positive to COVID-19 virus. After signing informed consent and undergoing screening assessments, eligible patients will record few times a day several pre-defined sentences to the Cordio App installed in a…
- Trial name
- NCT04325048
- Testing
- Cordio App
- Where
- Israel
- Volunteers
- 42 people
- Sponsor
- Cordio Medical
Vaccination
Effect of Electronic and Mail Outreach From Primary Care Physicians for COVID-19 Vaccination Among Elderly Patients
This randomized controlled trial tested the effect of culturally tailored and standard electronic secure messages and mailings from patients' primary care physicians to encourage COVID-19 vaccination among adults aged 65 and…
- Trial name
- NCT05096026
- Testing
- Standard PCP Outreach, Culturally Tailored PCP Outreach
- Where
- United States
- Volunteers
- 8,287 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Bronchoalveolar Lavage
Bronchoalveolar Lavage in Recovered From COVID-19 Pneumonia
Coronaviruses such as SARS-CoV2, MERS-CoV, and SARS-CoV can cause significant morbidity and mortality in infected persons. Lung is the most common site of infection for these viruses, which may manifest as acute respiratory…
- Trial name
- NCT06022198
- Testing
- Bronchoalveolar Lavage
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mohamed Abd Elmoniem Mohamed
Covid19
Efficacy and Safety Evaluation of Inhaleen Inhalation in Hospitalized COVID-19 Patients
The current study will investigate the tolerability and efficacy of inhaled Carragelose® versus saline in hospitalized COVID-19 patients.
- Trial name
- NCT04793984
- Testing
- Carragelose, NaCl
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Marinomed Biotech AG
Covid19, Venous Thromboembolism
Medically Ill Hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis With Rivaroxaban ThErapy: The MICHELLE Trial
The Michelle trial is expected to provide high-quality evidence around the role of extended thromboprophylaxis in COVID-19 and will help guide medical decisions in clinical practice.
- Trial name
- MICHELLE (NCT04662684)
- Testing
- Rivaroxaban 10 MG
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- Science Valley Research Institute
SARS-CoV-2
Solid Organ Transplant Recipients With SARS-CoV-2 French Registry
Patients with comorbid condition are known to be at high risk of severe forms of Covid-19. It is highly probable that immunocompromised patients like solid organ transplant (SOT) recipients are also at risk of severe forms of…
- Trial name
- TX-COVID (NCT04360707)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
COVID, SARS-CoV-2
European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO
In the last 10 years, severe acute respiratory infection (SARI) was responsible of multiple outbreaks putting a strain on the public health worldwide.
- Conditions
- COVID, SARS-CoV-2, ARDS, Human, Refractory Hypoxemia
- Trial name
- EuroECMO-COVID (NCT04366921)
- Where
- 97 sites in Austria, Belgium and 17 more
- Volunteers
- 150 people
- Sponsor
- Maastricht University Medical Center
COVID-19 Pandemic, Simulation of Physical Illness
COVID-19 Simulation Education on Nursing Students
This study aims to determine the effect of simulation education as an approach to patients with COVID-19 on nursing students' perception and fear of the COVID-19 disease.
- Trial name
- NCT05576636
- Testing
- Simulation training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Coronavirus
Silmitasertib (CX-4945) in Patients With Severe Coronavirus Disease 2019 (COVID-19)
This multi-center, open-label, 2 arm parallel-group, randomized, interventional prospective exploratory study in 40 patients aimed to evaluate safety and explore putative clinical benefits of Silmitasertib 1000 mg BID dose in…
- Trial name
- CX4945 (NCT04668209)
- Testing
- Silmitasertib
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Arizona
COVID-19
Efficacy and Safety of Favipiravir in the Treatment of COVID-19 Patients Over 15 Years of Age
This study is an observational study (Non-interventional study) to evaluate the safety and efficacy of favipiravir in patients older than 15 years of age, diagnosed with COVID-19 and initiated treatment with favipiravir before…
- Trial name
- NCT04474457
- Testing
- Favipiravir
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Ministry of Health, Turkey
SARS CoV 2 Infection, COVID-19
Humoral and Cellular Immunity in First-cycle SARS-CoV-2 Vaccinated COVID-19 Patients
Infection by the recent Coronavirus (SARS-CoV-2) has generated at a pandemic level a new pathology, called COVID-19, characterized by "flu-like" symptoms up to severe acute respiratory failure.
- Trial name
- NCT05338736
- Testing
- LIAISON SARS-CoV-2 TrimericS IgG (DiaSorin), LIAISON SARS-CoV2-IgM (DiaSorin), Human IFN-g ELISpot PLUS (ALP) (AUROGENE)
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- University Magna Graecia
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm
Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic
This study investigates the well-being and health-related quality of life in cancer patients and survivors during the COVID-19 pandemic.
- Conditions
- COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04500600
- Testing
- Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 13,378 people
- Sponsor
- M.D. Anderson Cancer Center
Ards, Mechanical Ventilation Pressure High
Prognostic Value of Respiratory System Compliance Under VV-ECMO on 180-day Mortality in COVID-19 ARDS.
Mortality of patients with COVID-19 associated acute respiratory distress syndrome (CARDS) treated with veno-venous extra-corporal membrane oxygenation (vv-ECMO) is increasing over time since the beginning of the COVID-19…
- Conditions
- Ards, Mechanical Ventilation Pressure High, Extracorporeal Membrane Oxygenation
- Trial name
- COMPLIECMO (NCT05341687)
- Testing
- No applicable
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Central Hospital, Nancy, France
COVID-19
Nutrition and LOComotoric Rehabilitation in Long COVID-19
Long COVID is a new phenomenon, in which individuals who experienced a SARS-CoV-2 infection still experience one or more symptoms, such as exercise intolerance, fatigue and/or muscle pains in addition to other COVID-related…
- Trial name
- UNLOCK (NCT05254301)
- Testing
- Intervention group
- Where
- Belgium
- Volunteers
- 65 people
- Sponsor
- Universitair Ziekenhuis Brussel
Acute Hypoxemic Respiratory Failure, COVID-19
Dexamethasone and Oxygen Support Strategies in ICU Patients With Covid-19 Pneumonia
The main manifestation of COVID-19 is acute hypoxemic respiratory failure (AHRF). In patients with AHRF, the need for invasive mechanical ventilation is associated with high mortality. Two hypotheses will be tested in this study.
- Trial name
- COVIDICUS (NCT04344730)
- Testing
- Dexamethasone injection, conventional oxygen, CPAP
- Where
- France
- Volunteers
- 550 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
the Use of Modern Technology Applications in Home Isolation
The Validity of Modern Mobile Applications in Management of COVID-19 Home Isolation Patients: a Survey for Health Care Professionals
In late 2019, a novel coronavirus, SARS-CoV-2, was identified as the causative agent of a cluster of pneumonia cases (COVID-19) in Wuhan, China. Clinical symptoms of COVID-19 may be mild or severe.
- Trial name
- NCT04548492
- Testing
- Survey
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
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