Clinical trials: COVID19 Patients
COVID-19
A Single-center Retrospective Study to Find Prediction Factors Related to Mortality of COVID-19 Patients.
In the single-centered, retrospective study, 306 hospital patients (including 129 diabetes and 177 non-diabetes patients) confirmed with SARS-CoV-2 infection were enrolled in Tongji Hospital, Wuhan, China.
- Trial name
- NCT04365634
- Where
- China
- Volunteers
- 306 people
- Sponsor
- Tongji Hospital
COVID-19
Clinical Trials to Assess Safety and Efficacy of DWRX2003 Combination With Remdesivir in Moderate to Severe COVID-19 Patients.
Safety and efficacy of DWRX2003 combination with Remdesivir in moderate to severe COVID-19 patients will be confirmed.
- Trial name
- NCT05226533
- Testing
- DWRX2003
- Where
- 3 sites in Indonesia
- Volunteers
- 1 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
COVID-19
An Adaptive Study of Favipiravir Compared to Standard of Care in Hospitalized Patients With COVID-19
The study is Phase II/III and consists of pilot and pivotal stages. The objective of the pilot stage is to conduct a preliminary assessment of the efficacy and safety of Favipiravir, and to select the optimal dosing regimen to…
- Trial name
- NCT04434248
- Testing
- Favipiravir, Standard of Care
- Where
- 22 sites in Russia
- Volunteers
- 330 people
- Sponsor
- Chromis LLC
SARS-CoV-2 Infection, COVID-19
An International Randomized Trial of Additional Treatments for COVID-19 in Hospitalized Patients Who Are All Receiving the Local Standard of Care - WHO-SOLIDARITY-GERMANY
This study is an adaptive, randomized, open-label, controlled clinical trial, performed worldwide in collaboration with WHO and INSERM.
- Conditions
- SARS-CoV-2 Infection, COVID-19, Moderate and Severe COVID-19
- Trial name
- NCT04575064
- Testing
- Standard of Care (SoC), Remdesivir
- Where
- 4 sites in Germany
- Sponsor
- Professor Dr. Bernd Mühlbauer
COVID-19
Retrospective Cohort Study of the Physiotherapy in Critically Ill Covid Patients
Retrospective cohort study that will include patients from the ICU of the Hospital de la Santa Creu i Sant Pau in Barcelona during the period between March 11 and May 13, 2020.
- Trial name
- NCT06042881
- Where
- Spain
- Volunteers
- 189 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Covid19
IFN Beta-1b and Ribavirin for Covid-19
As of 1 July 2020, more than 10 million people been confirmed to have infected by SARS-CoV-2, resulting in more than 500,000 deaths.
- Trial name
- NCT04494399
- Testing
- Interferon beta-1b, Ribavirin
- Where
- Hong Kong
- Volunteers
- 96 people
- Sponsor
- The University of Hong Kong
COVID-19, Critical Illness
Impact and Sequelae of High Ventilatory Drive in Critically Ill COVID-19 Patients
Critically ill COVID-19 patients with acute respiratory failure, in the intensive care unit (ICU), often feature high respiratory drive, determining large inspiratory efforts resulting in high pressures and global and regional…
- Conditions
- COVID-19, Critical Illness, Hypoxemic Respiratory Failure, Neurocognitive Dysfunction
- Trial name
- NCT05363332
- Where
- 3 sites in Spain
- Volunteers
- 126 people
- Sponsor
- Corporacion Parc Tauli
Post-COVID-19 Syndrome
Complementary Self-help Strategies for Patients With Post-COVID-19 Syndrome
Individuals affected by SARS-CoV-2 infection may subsequently be affected by the so-called post-COVID syndrome. The aim of the present study is to investigate the effects of a multimodal 10-week group program consisting of…
- Trial name
- NASH-POCO (NCT05798221)
- Testing
- Complementary self-help strategies in addition to treatment as usual, Treatment as usual
- Where
- Germany
- Volunteers
- 86 people
- Sponsor
- Universität Duisburg-Essen
Colorectal Cancer (CRC) and Pancreatic Cancer (PaCa)
Allocating Resources for Cancer Care in Times of the Sars-CoV-2 Outbreak. Health Care Research
The focus on treatment of COVID19 patients during the Sars-CoV-2 outbreak has most likely implications for the extent and quality of diagnosis and treatment of non-COVID19 patients.
- Trial name
- NCT05479292
- Testing
- Sars-CoV-2 outbreak
- Where
- Germany
- Volunteers
- 6,500 people
- Sponsor
- Technische Universität Dresden
Post-Viral Fatigue Syndrome
Rehabilitation Robot in Patients With Post-Coronavirus Disease (COVID-19) Fatigue Syndrome
The aim of the study is to compare the effectiveness of two models of rehabilitation: traditional neurological rehabilitation, and neurological rehabilitation combined with a rehabilitation robot (Luna by EGZOTech).
- Trial name
- NCT05130736
- Testing
- Robot rehabilitation
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Medical Sciences
COVID-19
A Study of Human Monoclonal Antibodies, BRII-196 and BRII-198
The aim of this phase 2 study is to evaluate the safety and efficacy of single dose IV infusion of BRII-196 and BRII-198 given as combination therapy in patients with severe COVID-19, and mild to moderate COVID-19 and…
- Trial name
- NCT04787211
- Testing
- BRII-196 and BRII-198
- Where
- 6 sites in China
- Volunteers
- 48 people
- Sponsor
- Brii Biosciences Limited
Covid19
Impact of Vitamin D Level and Supplement on SLE Patients During COVID-19 Pandemic
Aim of the work Impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection, duration of COVID-19 disease course, fatigue development as a complication for both SLE and COVID-19 and assess impact of…
- Trial name
- NCT04709744
- Testing
- Vitamin D, ELISA
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Mansoura University
COVID-19
Survey: COVID-19 Patients Managed in the Operating Theatre of Belgian Hospitals
COVID-19 pandemic has an important impact on the health care provided by the anesthesiologists. Different societies of anesthesiology have provided guidelines and recommendations on how to manage patients who have been tested…
- Trial name
- COVID (NCT04376398)
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
COVID-19, ARDS
Respiratory and Hemodynamic Changes Induced in Mechanically Ventilated Patients for COVID-19
In the present context, it seems necessary to try to describe as precisely as possible the physiological alterations due to COVID-19.
- Conditions
- COVID-19, ARDS, Sars-CoV2
- Trial name
- PHYSIO-COVID (NCT04347928)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Lille
Covid19, Cardiovascular Complication
WEAICOR: Wearables to Investigate the Long Term Cardiovascular and Behavioral Impacts of COVID-19
This is an observational COVID-19 study that uses wearable health monitoring technology to follow COVID-19 positive individuals to monitor persistent symptoms and any potential long-term complications or cardiovascular and…
- Conditions
- Covid19, Cardiovascular Complication, Behavioral Changes
- Trial name
- WEAICOR (NCT04605965)
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tulane University
Covid19, COVID19 Infection
State of Oxygen Metabolism, Cardiovascular and Respiratory System Reserve Capacity in Patients Who Underwent COVID-19
This clinical study will create an evidence base for rehabilitation approach, which will be used for restoration of pulmonary ventilation and gas exchange, increase of tolerance to physical load reduced in patients who underwent…
- Trial name
- NCT05911100
- Testing
- Spirography and assessment of pulmonary diffusion capacity, Cardiopulmonary stress test, Computed tomography of the chest organs
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronavirus Infection
Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19
Multicenter observational/registry study of the clinical features and outcomes of critically ill patients with COVID-19.
- Trial name
- STOP-COVID (NCT04343898)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 5,154 people
- Sponsor
- Brigham and Women's Hospital
COVID-19
Investigation of the B- and T-cell Repertoire and Immune Response in Patients With Acute and Resolved COVID-19 Infection
Background: People who get infected with COVID-19 have an unpredictable risk to worsen and die. This makes it hard to decide who can quarantine at home and who should be treated at a hospital.
- Trial name
- NCT04362865
- Where
- 4 sites in United States
- Volunteers
- 679 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
COVID
Avdoralimab an Anti-C5aR Antibody, in Patients With COVID-19 Severe Pneumonia ( FORCE )
The primary objective of this trial is to improve the proportion of COVID-19 patients with severe pneumonia who no longer need to be hospitalized, and to reduce the need for and duration of mechanical ventilation in patients with…
- Trial name
- FORCE (NCT04371367)
- Testing
- avdoralimab
- Where
- France
- Volunteers
- 208 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cancer & COVID 19
Epidemiology of SARS-CoV-2 and Mortality to Covid19 Disease in French Cancer Patients
To determine the prevalence and the 3-months incidence of SARS-CoV-2 in cancer patients (Part A). To evaluate the Covid-19 disease-specific mortality rate in cancer patients treated by hydroxychloroquine and azithromycin (Part B).
- Trial name
- ONCOVID (NCT04341207)
- Testing
- Hydroxychloroquine, Azithromycin
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
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