Clinical trials: COVID19 Patients
COVID-19
A Study to Compare the Efficacy of GNS561 Versus Standard of Care in Patients With SARS-CoV-2 (COVID-19) Infection
This is a multicenter, open-label, controlled, randomized phase 2 study designed to evaluate the safety and efficacy profile of GNS561 in patients with COVID-19.
- Trial name
- CureCovid-2019 (NCT04637828)
- Testing
- GNS561
- Where
- France
- Volunteers
- 178 people
- Sponsor
- Genoscience Pharma
COVID-19, SARS-CoV2 Infection
COVID Card Pilot Study to Detect Antibodies to SARS-CoV-2
This study aims to investigate the clinical performance characteristics of the novel point-of-care, semi-quantitative test for SARS-CoV-2 in the Emergency Department compared to the gold standard (ELISA).
- Trial name
- NCT05196932
- Testing
- Novel point-of-care, semi-quantitative test for SARS-CoV-2 antibodies
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Quality of Life, Colorectal Cancer
Quality of Life and Survival of Patients With Colorectal Cancer 5 Years After Surgery - Follow-up of the RCT DIQOL
This observational follow-up study of the randomized trial (RCT) DIQOL investigates long-term effects of an intervention with quality of life (QoL) diagnosis and therapy on present QoL, survival, and recurrence-free survival of…
- Conditions
- Quality of Life, Colorectal Cancer, Colorectal Neoplasms, Survivorship
- Trial name
- DIQOLFollow-up (NCT04930016)
- Testing
- Quality of life diagnosis and therapy during the completed RCT DIQOL
- Where
- Germany
- Volunteers
- 208 people
- Sponsor
- Tumor Center Regensburg
Coronavirus Infection
The COVID-19 ICU PRAYER Study
This is a multicenter; double blind randomized controlled study investigating the role of remote intercessory multi-denominational prayer on clinical outcomes in COVID-19 + patients in the intensive care unit.
- Trial name
- NCT04361838
- Testing
- prayer
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Kansas City Heart Rhythm Institute
Covid19, Breast Cancer Stage
COVID-19 Pandemic: Effect on Management of Patients With Breast Cancer
The objective was to find out the impact of COVID-19 on stage of breast cancer at presentation and its effects on overall onco-surgical management.
- Conditions
- Covid19, Breast Cancer Stage, Isolation, Social, Locally Advanced Breast Cancer
- Trial name
- COVID-19 (NCT04929964)
- Testing
- MRM , Toilet Mastectomy , BCS
- Where
- Pakistan
- Volunteers
- 87 people
- Sponsor
- Mehwish Mooghal , MBBS
Covid19, Microcirculation
COVID-19 Associated Endothelial Dysfunction Study
SARS-CoV-2 enters human cells through the binding of the spike protein with angiotensin converting enzyme-2 (ACE2), a membrane receptor highly expressed in immune or non-immune cells, and in many organs, including lungs and…
- Trial name
- CAUSED (NCT04773899)
- Testing
- Procedure : Multimodal microvascular assessment at study inclusion
- Where
- 2 sites in France
- Volunteers
- 75 people
- Sponsor
- University Hospital, Angers
COVID-19
Duke COVID-19 Shared Data and Specimen Repository
The purpose of this data repository is to provide a secure and centralized storage location and resource for the collection of essential data and medical specimens, across COVID-19 related protocols at Duke.
- Trial name
- NCT04368234
- Where
- United States
- Volunteers
- 100,000 people
- Sponsor
- Duke University
Neoplasms, Cancer, Treatment-Related
BNT162b2 Messenger Ribonucleic Acid (mRNA) Covid-19 Vaccine in Cancer Patients on Active Treatment
In this Italian observational study the antibody titer reactogenicity to Pfizer Severe Acute Respiratory Syndrome (SARS) - Coronavirus (CoV-2) RNA vaccine in cancer patients under active antitumor treatment will be evaluated at…
- Trial name
- UNICO (NCT04932863)
- Testing
- BNT162b2 mRNA Covid-19 Vaccine
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Covid19
Assessment of Long-term Impact Post COVID-19 for Patients and Health Care Professionals of the European Hospital
The purpose of the study is to Assess of Long-term impact post COVID for patients and health care professionals.The patients and medical staff will be followed for 2 years in order to provide clinical and paraclinical data not…
- Trial name
- ALCOVID (NCT04525911)
- Testing
- Diagnostic Test: serology test for COVID-19
- Where
- France
- Volunteers
- 214 people
- Sponsor
- Hôpital Européen Marseille
COVID-19
Risks of Bacterial and Fungal Superinfection in Patients With COVID-19
Infection with bacteria or fungi can be deadly. Often, these types of infections can lead to an increase in the severity of illness requiring intensive care unit (ICU) admission, prolonged duration of treatment and further risks…
- Trial name
- NCT05256316
- Testing
- Previously admitted COVID-19 patients in intensive care units
- Where
- 5 sites in United States, Australia and 3 more
- Volunteers
- 790 people
- Sponsor
- The University of Queensland
Treatment of Covid-19 Virus Infection
Effect of a Combination of Treatment of Reginmune Capsule and Immunofree Tablets in the Treatment of Mild to Moderate COVID-19 Patients
While novel drug discovery and vaccine studies are time taking process, re-purposing old drugs against the COVID-2019 epidemic can help identify treatments, with known pre-clinical, pharmacokinetic, pharmacodynamic, and toxicity…
- Trial name
- NCT04494204
- Testing
- Immunofree tablets and Reginmune capsule
- Where
- 3 sites in India
- Volunteers
- 100 people
- Sponsor
- PUNEET MITTAL
COVID-19
Antiviral Agents Against COVID-19 Infection
A key strategy in the treatment of COVID-19 would be to find an effective antiviral agent that would decrease the peak viral load and, consequently, the associated degree of immunopathological damage that follows this phase.
- Trial name
- REVOLUTIOn (NCT04468087)
- Testing
- Atazanavir, Daclatasvir 60 mg, Sofusbuvir + Daclastavir 60 mg
- Where
- Brazil
- Volunteers
- 256 people
- Sponsor
- Hospital do Coracao
COVID-19, Azvudine
The Real-world Clinical Study of Azvudine Tablets in the Treatment of COVID-19
To establish a real-world clinical cohort and database of Azvudine in the treatment of SARS-CoV-2 infection, and to provide stable and reliable evidence for the clinical efficacy and safety evaluation of azvudine in the treatment…
- Trial name
- NCT06349655
- Testing
- Azvudine, Paxlovid
- Where
- China
- Volunteers
- 32,864 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
COVID-19
Trial to Study the Efficacy and Safety of BEJO Red Ginger in COVID-19 Patients With Mild Symptoms
This study is a randomized, double-blind, placebo-controlled clinical trial to investigate the safety and efficacy of BEJO Red Ginger in hospitalized adult (18 - 50 years old) COVID-19 patients with mild clinical manifestations.
- Trial name
- NCT05277155
- Testing
- BEJO Red Ginger Extract
- Where
- Indonesia
- Volunteers
- 168 people
- Sponsor
- Research Center for Chemistry, National Research and Innovation Agency of Indonesia
Coronavirus Infection
Change in the Ratio of Mean Platelet Volume (MPV) to Platellet(PLT) in Covid-19 Pneumonia Patients
Morbidity, mortality and progress depends on systemic inflammation especially in ARDS patients. Previous studies claims that the proportion of mean platellet volume to platellet which can simply be determined with simple blood…
- Trial name
- NCT04408378
- Testing
- observation of covid 19 pneumonia
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Chronic Fatigue Syndrome, Intensive Care Unit
Chronic Fatigue Etiology and Recovery in Covid-19 Patients: the Role of Fatigability
Chronic fatigue is the most common and debilitating symptom in intensive care unit (ICU) survivors. Indeed, it has been widely reported that patients who stayed in ICU for prolonged periods report a feeling of tiredness for…
- Conditions
- Chronic Fatigue Syndrome, Intensive Care Unit, Muscle
- Trial name
- FatCovid-19 (NCT04363606)
- Testing
- Questionnaires, blood test, Maximal effort test
- Where
- 8 sites in France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
COVID - 19
Open Label Study to Compare Efficacy, Safety and Tolerability of Hydroxychloroquine Combined With Azithromycin Compared to Hydroxychloroquine Combined With Camostat Mesylate and to "no Treatment" in SARS CoV 2 Virus
Patients with COVID-19 which are 60 years old or above or with comorbidities are at risk of deteriorating and developing severe illness.
- Trial name
- COSTA (NCT04355052)
- Testing
- hydroxychloroquine in combination with camostat mesylate, Hydroxychloroquine in combination of Azithromycin
- Where
- 2 sites in Israel
- Volunteers
- 250 people
- Sponsor
- Sheba Medical Center
Corona Virus Infection
Cohort Multiple Randomized Controlled Trials Open-label of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients
The overall objective of the study is to determine which treatments (e.g. immune modulator drugs) have the most favorable benefit-risk in adult patients hospitalized with COVID-19 either diagnosed with moderate or severe…
- Trial name
- CORIMUNO-19 (NCT04324047)
- Where
- 3 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19, Respiratory Failure With Hypoxia
Elmo Respiratory Support Project - COVID-19
The number of COVID-19 cases has been growing exponentially, so that the industrialized economies are facing a significant shortage in the number of ventilators available to meet the demands imposed by the disease.
- Trial name
- NCT04470258
- Testing
- ELMO PROJECT AT COVID-19: STUDY IN HUMANS, ELMO PROJECT AT COVID-19: PROOF OF CONCEPT AND USABILITY
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Escola de Saúde Pública do Ceará
Respiratory Disease
Analysis of Vital Signs in Patients With COVID-19
This project will use data obtained from a proprietary vision-based patient monitoring and management system (OxeVision) for measuring heart rate and respiratory rate which is in clinical use at the Coventry and Warwickshire…
- Trial name
- NCT04927078
- Testing
- Observation of breathing pattern
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Oxehealth Limited
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