Clinical trials: COVID19 Patients
COVID-19, Coronavirus
CONTAIN COVID-19: Convalescent Plasma to Limit COVID-19 Complications in Hospitalized Patients
This is a randomized, blinded phase 2 trial that will assess the efficacy and safety of anti-SARS-CoV-2 convalescent plasma in hospitalized patients with acute respiratory symptoms requiring oxygen supplementation.
- Conditions
- COVID-19, Coronavirus, Coronavirus Infection
- Trial name
- NCT04364737
- Testing
- Convalescent Plasma, Saline solution
- Where
- 9 sites in United States
- Volunteers
- 941 people
- Sponsor
- NYU Langone Health
Oral Health and COVID 19
Oral Manifestation of COVID 19 Patient: A Cross Sectional Study on Egyptian Population
The oral manifestation of COVID 19 that could help in the diagnosis of patient
- Trial name
- NCT04391881
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Covid19, NAFLD
COVID-19 and Nonalcoholic Fatty Liver Disease
COVID-19 is currently the leading public health problem, associated with a high risk of complications and death in risk groups of patients.
- Trial name
- CovidFAT (NCT04982328)
- Testing
- Th17 cytokine profile, Screening for the components of metabolic syndrome, Evaluation of the degree of steatosis
- Where
- Croatia
- Volunteers
- 120 people
- Sponsor
- University Hospital for Infectious Diseases, Croatia
COVID-19, SARS-CoV Infection
Seroprevalence Study of CoV-2-SARS (COVID-19) Infection in Patients With Chronic Inflammatory Rheumatic Diseases
The prevalence of SARS-CoV-2 infection in chronic inflammatory rheumatic diseases has not yet been widely reported, and has been evaluated only in symptomatic patient samples.
- Conditions
- COVID-19, SARS-CoV Infection, Rheumatoid Arthritis, Spondyloarthritis
- Trial name
- COVID-RIC1 (NCT04655612)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Montpellier
Apnea, Obstructive Sleep, SARS CoV 2 Infection
Impact of Sleep Disorders on Innate Immunity in COVID-19 Patients
Sleep is an important modulator of the immune response, whereby sleep disturbances (ie, poor sleep quality, insufficient sleep and/or primary sleep disorder, obstructive sleep apnea (OSA)) contribute to inflammatory disease risk…
- Trial name
- NCT06341374
- Testing
- Influvac Tetra
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Parc Taulí Hospital Universitari
Covid19, Respiratory Muscle Training
Effects of Respiratory Muscle Training in People Who Have Had COVID-19 Disease
The main objective of the present study is to observe the short-term effects of respiratory muscle training applied by telerehabilitation on quality of life and exercise tolerance in people who have had the COVID-19 disease.
- Conditions
- Covid19, Respiratory Muscle Training, Respiratory Function Test, Quality of Life
- Trial name
- NCT04734561
- Testing
- Inspiratory muscle training group, Inspiratory + expiratory muscle training group
- Where
- Spain
- Volunteers
- 88 people
- Sponsor
- Universidad Complutense de Madrid
Covid19, SARS-CoV Infection
Characterization Immunology, Biochemical and Lung Microbiome, Correlated With the Ventilation Associated Pneumonia (VAP)
SARS-CoV-2, the virus that causes COVID-19, is currently a global public health problem, declared a pandemic by the World Health Organization, which today has more than one million deaths in the world, of which , 30,000…
- Trial name
- MicroNAV-II (NCT04944823)
- Testing
- Clinical follow-up for 24 months
- Where
- Colombia
- Volunteers
- 50 people
- Sponsor
- Universidad de la Sabana
Coronavirus Disease 2019
Evolution of Coronavirus Disease 2019 (COVID-19) Patients in Extremadura
At the end of January 2020, the international community was informed of the presence of a new viral disease that started in Wuhan (China) and spread rapidly throughout the world.
- Trial name
- COVIXTREM (NCT04724850)
- Where
- Spain
- Volunteers
- 440 people
- Sponsor
- Juan Fernando Masa Jiménez
Covid-19
Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Ambulatory Patients With Mild COVID-19
This is an exploratory study to evaluate the efficacy of hydroxychloroquine (400 mg BID on D1 and 400 mg/day on D2 to D7) and azithromycin (500 mg/ 5 days) to treat mild ambulatory COVID-19 patients.
- Trial name
- NCT04348474
- Testing
- Hydroxychloroquine Sulfate, Azithromycin Tablets
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Azidus Brasil
Covid19
Profiling of Post Covid-19 Infection Patients: an Online Survey
The aim of this study is to explore the relation between indicators of central sensitisation, quality of life and functional status in patients post covid-19 infection.
- Trial name
- PRESTO (NCT04912778)
- Testing
- Filling in an online survey
- Where
- Belgium
- Volunteers
- 567 people
- Sponsor
- Moens Maarten
Long COVID, Post-COVID Syndrome
Human Umbilical Cord Blood (RegeneCyte) Infusion in Patients with Post-COVID Syndrome
REGENECYTE (HPC, Cord Blood, hUCB) for treatment in patients with post-COVID.
- Conditions
- Long COVID, Post-COVID Syndrome, Post COVID-19 Condition
- Trial name
- NCT05682560
- Testing
- REGENECYTE
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- StemCyte, Inc.
COVID-19
High-dose Hydroxychloroquine for the Treatment of Ambulatory Patients With Mild COVID-19
This study aims to examine the tolerability of high dose hydroxychloroquine in patients with COVID-19 who are not yet hospitalized, but have risk factors for disease progression and complications.
- Trial name
- NCT04351620
- Testing
- Hydroxychloroquine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Chicago
Mesenchymal Stem Cell, COVID-19 Pneumonia
UC-MSCs in the Treatment of Severe and Critical COVID-19 Patients
The goal of this randomized, controlled, open-labeled interventional clinical trial is to test the efficacy and safety of umbilical cord mesenchymal stem cells (UC-MSCs) in the treatment of severe and critical COVID-19 patients.
- Trial name
- NCT05682586
- Testing
- umbilical cord mesenchymal stem cells, paxlovid
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai East Hospital
Asymptomatic COVID-19 Infection Laboratory-Confirmed, B-Cell Neoplasm
Ibrutinib for the Treatment of Patients With B-Cell Malignancies Who Are Infected With Coronavirus Disease 2019 (COVID-19)
This phase II trial studies the effects of ibrutinib in treating patients with B-cell malignancies who are infected with COVID-19.
- Conditions
- Asymptomatic COVID-19 Infection Laboratory-Confirmed, B-Cell Neoplasm, Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
- Trial name
- NCT04665115
- Testing
- Ibrutinib, Quality-of-Life Assessment
- Where
- United States
- Sponsor
- Academic and Community Cancer Research United
Influenza Infection, SAD-RV Infection and COVID-19
DAS181 for Patients With Severe Hospitalized Flu and SAD-RVs (COVID-19)
This is a Phase IIb study consisting of two cohorts to evaluate efficacy, safety and pharmacokinetics of DAS181 in IFV infection. An approximate total of 280 subjects will be enrolled into this study.
- Trial name
- STOP-Flu (NCT04298060)
- Testing
- DAS181
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Ansun Biopharma, Inc.
Covid19, Taste Disorder, Secondary
Lactoferrin for COVID-19-Induced Taste or Smell Abnormality
Common side effects of corona virus disease 2019 (COVID-19) include disruptions in taste and smell function, which may persist for prolonged periods of time following recovery and resolution of COVID-19 infection.
- Conditions
- Covid19, Taste Disorder, Secondary, Taste Disorders, Dysgeusia
- Trial name
- TSA (NCT05760079)
- Testing
- Lactoferrin
- Sponsor
- Wake Forest University Health Sciences
Covid19
Study of Codivir in Patients With COVID-19
This is an open-label study to evaluate the safety and preliminary efficacy of Codivir in 12 mild or moderate COVID-19 patients and onset of symptoms within 72h prior to their inclusion.
- Trial name
- Codivir (NCT04930861)
- Testing
- Covidir injections, One Step Test, IgM and IgG dosage
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Code Pharma
COVID-19
Markers of Severity (CD177,S100A8 &S100A12) in Sever Acute Respiratory Syndrome Coronavirus 2(SARS-COV-2) Patients
Patients infected with covid-19 have a series of clinical manifestations, including fever, cough, myalgia or fatigue, dyspnea, even acute respiratory distress syndrome (ARDS), acute cardiac injury and secondary infection, and a…
- Trial name
- NCT05201625
- Testing
- real time PCR
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
COVID-19
Neutrophil Side Fluorescent Light (NEU-SFL) in COVID-19 Patients
Recently, a study showed that markers of neutrophil extracellular traps formation, a mechanism corresponding to neutrophil activation, were increased in patients who died of COVID 19 compared with survivors.
- Trial name
- NEU-COVID (NCT05413824)
- Where
- France
- Volunteers
- 2,233 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Lymphocytic Leukemia, Lymphocytic Lymphoma or Waldenstrom Disease
Observatory of Patients With Chronic Lymphocytic Leukemia / Lymphocytic Lymphoma or Waldenstrom Disease Infected With COVID-19
The COVID-19 epidemic (Coronavirus Disease 2019) which is currently raging in France is an emerging infectious disease linked to a virus of the genus coronavirus (SARS-CoV-2).
- Trial name
- COVID19_LLC-MW (NCT04391946)
- Testing
- Data registry
- Where
- 22 sites in France
- Volunteers
- 162 people
- Sponsor
- French Innovative Leukemia Organisation
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