Clinical trials: COVID19 Patients
Aplastic Anemia, Hematopoietic and Lymphoid Cell Neoplasm
Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization
This phase Ib/II trial studies the side effects and best dose of ibrutinib and how well it works in treating patients with COVID-19 requiring hospitalization.
- Conditions
- Aplastic Anemia, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Monoclonal B-Cell Lymphocytosis
- Trial name
- NCT04439006
- Testing
- Best Practice, Ibrutinib
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jennifer Woyach
Myocardial Infarction
CMR Findings in COVID-19 Patients Presenting With Myocardial Infarction
To compare myocardial injury in COVID 19 patients presented with myocardial infarction and non COVID Patients presented with myocardial infarction evaluated with CMR
- Trial name
- NCT04628104
- Testing
- cardiac magnetic resonance
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
COVID-19 Pnemonia
Clinical Trial of the Use of Anakinra in Cytokine Storm Syndrome Secondary to Covid-19 (ANA-COVID-GEAS)
Phase 2/3 randomized, parallel group, 2-arm study (treatment vs. control), investigating the efficacy and safety of intravenous administration of anakinra, an interleukin 1 receptor antagonist ( IL-1), added to standard…
- Trial name
- ANA-COVID-GEAS (NCT04443881)
- Testing
- Anakinra 149 MG/ML Prefilled Syringe [Kineret]
- Where
- 12 sites in Spain
- Volunteers
- 179 people
- Sponsor
- Fundacion Miguel Servet
Acute Respiratory Diseases
Voice, Dyspnea and Acute Respiratory Failure
Breathing is an automatic vital function that has the peculiarity of being controllable voluntary for actions other than breathing.
- Trial name
- LocuPnée-H (NCT05340933)
- Testing
- Voice registration
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid19, Myocardial Injury
Semaglutide to Reduce Myocardial Injury in PATIents With COVID-19
With the results of this study the investigators aim to identify an effective treatment that will reduce morbidity and mortality of patients with symptomatic COVID-19 infection, which would in turn reduce the burden on the…
- Trial name
- SEMPATICO (NCT04615871)
- Testing
- semaglutide
- Where
- 10 sites in Brazil, Canada and 2 more
- Volunteers
- 400 people
- Sponsor
- Vladimír Džavík
Covid19
Characteristics and Outcomes of Hospitalized Patients With COVID-19 in Spain
COVID-19@Spain is a retrospective cohort study that aims to determine the clinical characteristics of hospitalized patients with COVID-19 in Spain and to identify prognostic factors of mortality and the need for mechanical…
- Trial name
- COVID19@Spain (NCT04355871)
- Where
- 128 sites in Spain
- Volunteers
- 4,035 people
- Sponsor
- Fundacion SEIMC-GESIDA
Covid19, Allied Health Professionals
Evaluation of Allied Healthcare in Patients Recovering From COVID-19
SUMMARY Rationale: Allied health professionals (i.e., dietitians, exercise therapists, physical therapists, occupational therapists and speech and language therapists) might play an important role in the recovery of patients with…
- Conditions
- Covid19, Allied Health Professionals, Primary Care, Retrospective Cohort
- Trial name
- ParaCOV (NCT04735744)
- Testing
- Patients recovering from COVID19 receive usual care by allied health professionals
- Where
- Netherlands
- Volunteers
- 1,441 people
- Sponsor
- Radboud University Medical Center
Covid19, Acute Kidney Injury
Acute Kidney Injury in Patients With CoVID-19
We aimed to investigate the effect of Acute Kidney Injury (AKİ) on the prognosis of patients hospitalised for COVID-19.
- Trial name
- AKI-COVID-19 (NCT04872764)
- Testing
- duration of hospitalization, mortality rate
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Uşak University
Coronavirus Disease-2019
Sequential Oxygen Therapy Strategy for Patients With COVID-19
All patients with COVID-19 were divided into three groups according to their illness: mild patient who receive conventional oxygen therapy, severe patients who receive nasal high flow oxygen inhalation or non-invasive positive…
- Trial name
- SOTSPC (NCT04312100)
- Testing
- oxygen treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Henan Provincial People's Hospital
Covid19, COVID-19 Vaccines
Immune Response to Anti COVID-19 Vaccine in Immunocompromised Patients: a Cohort Study
Despite COVID-19 pandemic having started more than one year ago, there are still limited treatment options for these patients, and over 145 million cases and 3 millions deaths have ensued worldwide.
- Trial name
- NCT04888793
- Testing
- Serologic immune response evaluation
- Where
- Chile
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Prone Position, Severe Acute Respiratory Syndrome Coronavirus 2
Evaluation of Sedation in COVID-19 ARDS
This study focuses on the evaluation of various factors repeatedly discussed in relation to the impaired sedation of intubated ventilated COVID-19 patients.
- Conditions
- Prone Position, Severe Acute Respiratory Syndrome Coronavirus 2, Hypnotics and Sedatives, Pulmonary Ventilation
- Trial name
- NCT04667936
- Testing
- Treatment group
- Where
- Germany
- Volunteers
- 114 people
- Sponsor
- Goethe University
SARS-CoV-2 Infection
Study to Evaluate the Efficacy and Safety of Oral RP7214, a DHODH Inhibitor, in Patients With Symptomatic Mild COVID-19 Infection.
This is a randomized, double-blind, placebo-controlled study of RP7214 in patients with symptomatic mild SARS-CoV-2 infection, having at least one high-risk feature (e.g., age > 60 years, hypertension, diabetes mellitus, chronic…
- Trial name
- NCT05007236
- Testing
- RP7214 + Standard of care (SOC)
- Where
- 16 sites in India
- Volunteers
- 163 people
- Sponsor
- Rhizen Pharmaceuticals SA
Covid19, Hypoxemic Respiratory Failure
Automatic Oxygen Titration With O2matic® to Patients Admitted With COVID-19 and Hypoxemic Respiratory Failure
Patients with coronavirus disease (COVID-19) and pneumonitis often have hypoxemic respiratory failure and a need of supplementary oxygen.
- Conditions
- Covid19, Hypoxemic Respiratory Failure, Hypoxemia
- Trial name
- O2matic-COVI (NCT04565106)
- Testing
- Closed-loop control of oxygen supplementation by O2matic
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Hvidovre University Hospital
Cancer; Chemotherapy
Immunological Responses of COVID-19 Vaccination
Cancer patients with COVID-19 have a 30% higher mortality rate compared to the general population and are considered a high-risk group by the American Association for Cancer Research that should be given "high priority" during…
- Trial name
- NCT05238467
- Testing
- COVID antibody titers in the blood
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Covid19
Early Use of Hyperimmune Plasma in COVID-19
The study assesses the efficacy of early administration of hyperimmune plasma in covid-19 patients who are on CPAP or intubated. Efficacy is measured as a 2 point decrease in the WHO scale
- Trial name
- COV-II-PLA (NCT04721236)
- Testing
- hyperimmune plasma
- Where
- Italy
- Volunteers
- 260 people
- Sponsor
- Catherine Klersy
Adult Patients Living With HIV (PLWHIV) With Confirmed Infection With SARS-CoV-2 Since 1st January 2020
Clinical Characterisation Protocol for COVID-19 in People Living With HIV
There is very little data so far to determine whether people living with HIV (PLWHIV) are at greater risk of COVID-19 acquisition or severe disease.
- Trial name
- COVIDHIV (NCT04361604)
- Testing
- Biological collection (patients co infected HIV Sras-CoV-2), Auto-questionnaires (patients co infected HIV Sras-CoV-2), Qualitative interviews (in 40 patients : 20 with COVID-19 and 20 without COVID-19)
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19 Infection, Parathyroid Gland
The Status of Parathyroid Hormone Secretion in Covid-19 Patients
COVID-19 infection causes a hypersensitive immune reaction and widespread inflammation in various organs of the body, especially through cytokines in the lungs.
- Conditions
- COVID-19 Infection, Parathyroid Gland, Parathyroid Hormone, Calcium
- Trial name
- NCT04662437
- Testing
- Venous blood was collected for biochemistry testing
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
SARS Pneumonia
Convalescent Plasma of Covid-19 to Treat SARS-COV-2 a Randomized Doble Blind 2 Center Trial
The new SARS-CoV-2 coronavirus is an emerging virus originating in Wuhan, China that has spread rapidly throughout the world. As of March 24, 2020, China had reported 81,767 cases with 3,281 deaths, and the World Health…
- Trial name
- CPC-SARS (NCT04405310)
- Testing
- Convalescent Plasma of patients with COVID-19
- Where
- 2 sites in Mexico
- Volunteers
- 42 people
- Sponsor
- Grupo Mexicano para el Estudio de la Medicina Intensiva
Atrial Fibrillation Paroxysmal
Physiotherapist-led Exercise Within Cardiac Rehabilitation and Paroxysmal Atrial Fibrillation and COVID-19.
Paroxysmal atrial fibrillation (AF) induce, in the affected patient, a prominent negative effect on health-related quality of life (HR-QoL) and physical fitness.
- Trial name
- NCT04600713
- Testing
- PT-X and IMT
- Sponsor
- Vastra Gotaland Region
Long COVID
Long-term Symptomatic Follow-up of Patients with Long COVID Syndrome
The goal of this observational study is to learn about the long-term evolution of long COVID. The main question it aims to answer is: Does the main symptoms of the patients diagnosed with long COVID aproximate to those of…
- Trial name
- NCT06879535
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital del Rio Hortega