Clinical trials: CPAP Treatment
Sleep Apnea Syndromes
Efficiency of a Phone Coaching for Sleep Apnea Hypopnea Syndrome Patients
Background: Continuous Positive Airway Pressure (CPAP) remains the reference treatment for moderate to severe forms of the Sleep Apnea/Hypopnea Syndrome (SAHS).
- Trial name
- NCT02435355
- Testing
- telephone-based counselling
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Sadir Association
Preeclampsia, Hypertension
CPAP in Preeclampsia
Study design: Single blinded randomised control trial Planned sample size: 30 (women randomized 2:1 to receive either CPAP or no CPAP) Objectives: Primary objective: Assess the effects of nasal CPAP on sleep physiology, 24 blood…
- Trial name
- NCT02303834
- Testing
- Continuous Positive Airway Pressure Ventilation (CPAP)
- Where
- 2 sites in Australia
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Ventilation Therapy; Complications
Ultrasound Measurements of Basilica Vein Diameter at Room Air Breathing and at Positive Pressure on Healthy Volunteers
Peripherally Inserted Central Catheters (PICC) and midline placement requires the catheter size to be one third of the venous diameter, or less.
- Trial name
- PEEPVEIN-2021 (NCT05201755)
- Testing
- CPAP
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Sleep Apnea, Obstructive
Evaluation of a Health Dashboard Intervention to Improve Engagement With CPAP Therapy in PAP-Naïve Patients: Project Neo
This is a prospective, open-label study to evaluate the effectiveness of providing a dashboard with merged health metrics of CPAP (continuous positive airway pressure/ PAP) usage, self-reported sleepiness, blood pressure (BP) and…
- Trial name
- NCT04912635
- Testing
- Neo App
- Where
- Australia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- ResMed
Ventilation Therapy
Cerebral Blood Flow: Helmet vs Oronasal Mask During Continuous Positive Airway Pressure Ventilation
In this trial the investigators will evaluate blood flow in common carotid artery of healthy subjects treated with Continuous Positive Airway Pressure (CPAP) Ventilation, comparing two different devices: oronasal mask versus…
- Trial name
- NCT06480253
- Testing
- Helmet Continuous Positive Airway Pressure, Oronasal Mask Continuous Positive Airway Pressure
- Where
- Italy
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Papa Giovanni XXIII Hospital
Preterm Infants, Nasal Continuous Positive Airway Pressure
Effect of Therapeutic Touch and Mother's Voice on Pain and Comfort Level During Nasal CPAP Application
Aim: This study was conducted to evaluate the effects of Therapeutic Touch and Mother's Voice on pain and comfort levels of preterm infants during nasal CPAP application.
- Conditions
- Preterm Infants, Nasal Continuous Positive Airway Pressure, Pain Management
- Trial name
- CPAP (NCT05577793)
- Testing
- Mother's Voice, Therapeutic Touch, Mother's Voice +Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Ayşe Belpınar
Chronic Obstructive Pulmonary Disease, Sleep Related Hypoventilation
Health Outcomes With CPAP or NIV in Patients With COPD and a Sleep Related Breathing Disorder
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease affecting an estimated 1 in 10 Canadians. Symptoms include persistent shortness of breath, cough and sputum production.
- Conditions
- Chronic Obstructive Pulmonary Disease, Sleep Related Hypoventilation, Obstructive Sleep Apnea, Hypoventilation
- Trial name
- NCT05623709
- Testing
- Positive airway pressure with continuous positive airway pressure or noninvasive ventilation
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Continuous Positive Airway Pressure, Endoscopy
Nasal CPAP - The Treatment IMpact on Oxygenation in High-risk Patients During Deep Sedation for Endoscopy
Deep sedation during gastrointestinal endoscopy in patients with cardiopulmonary risk factors such as respective co-morbidities or also morbid obesity is challenging.
- Conditions
- Continuous Positive Airway Pressure, Endoscopy, Oxygenation, Obesity
- Trial name
- NAPTIME (NCT06168682)
- Testing
- SuperNO2VA™ Et by Vyaire Medical, Inc., nasal oxygen cannula
- Where
- Germany
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Obstructive Sleep Apnea
Variable Negative External Pressure (vNEP) - An Alternative to Continuous Positive Airway Pressure (CPAP) for the Treatment of Obstructive Sleep Apnea (OSA): A Pilot Study
Non-compliance rates estimated at 50% pose a major issue for CPAP therapy, the primary treatment for OSA. Negative external pressure, applied over the anterior neck under the mandible, has shown encouraging results as an…
- Trial name
- NCT04718142
- Testing
- vNEP
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Somne, LLC
Obstructive Sleep Apnea of Adult
Assessment of Pulmonary Artery Pressure and Right Sided Hemodynamics in Patients With OSA Before and After CPAP TTT
Obstructive sleep apnea (OSA) is a frequent sleep-related breathing disorder with an incidence of 5-20% in the middle-aged population in Europe and Northern America .
- Trial name
- NCT03276611
- Testing
- echocardiograghy
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Excessive Daytime Sleepiness, Obstructive Sleep Apnea (OSA)
Validating a Novel Driving Simulation-based MWT Against the Standard MWT in an OSA-cohort Challenged by CPAP-withdrawal
In brief, the proposed study will evaluate a recently proposed naturalistic, driving simulation test to identify and measure sleepiness behind the wheel, one of the most underestimated causes of road accidents.
- Conditions
- Excessive Daytime Sleepiness, Obstructive Sleep Apnea (OSA), CPAP Treatment, Driving Simulator Performance
- Trial name
- DS-MWT2 (NCT06872593)
- Testing
- CPAP-withdrawal, Test Sequence
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Stefan Lakämper
Obstructive Sleep Apnea (OSA)
Differences in Efficacy Between Nasal and Oronasal Masks in the Treatment of OSA With CPAP
Our group previously conducted a study looking at the performance of three styles of positive airway pressure masks during laboratory treatment studies for obstructive sleep apnea, and we found that patients using a full-mask…
- Trial name
- NCT01909674
- Testing
- Switch CPAP mask type
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Organic Pediatric Obstructive Sleep Apnea
Nasal Expiratory Positive Airway Pressure for the Treatment of Pediatric Obstructive Sleep Apnea Syndrome
This study will evaluate effectiveness and adherence of the nasal expiratory positive airway pressure (NEPAP) device as an an alternate therapy for children with Obstructive Sleep Apnea Syndrome (OSAS).
- Trial name
- NCT01768065
- Testing
- Nasal Expiratory Positive Airway Pressure Device
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Hypertension Secondary
Characteristics of Obstructive Sleep Apnea Syndrome Related Hypertension and the Effect of Continuous Positive Airway Pressure Treatment on Blood Pressure
Obstructive sleep apnea syndrome (OSAS) causes nocturnal chronic intermittent hypoxia (CIH) that contributes to the development of hypertension.
- Trial name
- NCT03246022
- Testing
- continuous positive airway pressure
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Huai'an No.1 People's Hospital
Bronchopulmonary Dysplasia, Death
Continuous Positive Airway Pressure Via Binasal Prong vs Nasal Mask: a Randomised Controlled Trial
The investigators aimed to compare the effectiveness of nasal mask and prongs used in CPAP (nasal continuous positive airway pressure)as the initial respiratory support when using minimal ly invasive surfactant therapy (MIST) in…
- Trial name
- MASK (NCT02287116)
- Testing
- Easy Flow system and INCA® nasal cannulae set
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Obstructive Sleep Apnea, Adherence
Effort-based Decision-making and CPAP Adherence
Obstructive sleep apnoea is the most common sleep disorder in general population, and is often associated with cognitive deficit, mood disorders, hypertension, diabetes mellitus, excessive daytime somnolence, nicturia and an…
- Trial name
- NCT04557293
- Testing
- Continuous Positive Airway Pressure (CPAP) treatment
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Sleep Apnea, Obstructive, Healthy
Swallowing in OSA & CPAP Intolerance
This study has two parts: an observational part and an interventional part. The goal of the observational part of the study is to look for variations in swallowing in adults with obstructive sleep apnea (OSA) and in adults who…
- Trial name
- SLP-PAP (NCT06786117)
- Testing
- SLP swallowing exercises, myofunctional exercises
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Denise Dewald
Sleep Apnea, Obstructive
Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome
The primary objectives of the study are to determine the effectiveness of PROVIGIL treatment, compared to placebo treatment, in children and adolescents with excessive sleepiness (ES) associated with obstructive sleep…
- Trial name
- NCT00107809
- Testing
- Modafinil
- Where
- 64 sites in United States, Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cephalon
Respiratory Distress, Lung Injury
Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP
This study is designed to evaluate the effect of heated humidified high flow nasal cannula (HHHFNC) as compared to noninvasive nasal continuous positive airway pressure (NCPAP) on lung function as a measure of lung injury in…
- Trial name
- NCT01939067
- Testing
- Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Sleep Apnea, Obstructive
Dissection of Differentially Expressed Genes and Pathways in Patients With OSAS Before and After CPAP Treatment
Specific Aim 1. To verify the differentially expressed genes and pathways between normal and OSA patients, and OSA patients before and after CPAP treatment.
- Trial name
- NCT00498732
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital