Clinical trials: CPP
Tooth Demineralization
Study of Treatments Used for White Spot Lesions After Orthodontic Treatment.
The purpose of this study is to learn more about the management of white spot lesions that occur after orthodontic treatment. White spot lesions generally improve slightly with time.
- Trial name
- NCT01059058
- Testing
- MI Paste Plus, PreviDent Fluoride Varnish, Normal Home Care
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Washington
White Spot Lesion, Orthodontic Appliance Complication
A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.
The goal of this randomized clinical trial is to compare the influence of casein phosphopeptide amorphous calcium phosphate (CPP-ACP), CPP-ACP in combination with fluoride (CPP-ACPF), high fluoride concentration, and conventional…
- Trial name
- NCT05710874
- Testing
- CPP-ACP paste, CPP-ACPF paste, 1.25% fluoride gel
- Where
- Belgium
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Sensitivity, Tooth
The Association of CPP-ACPF Associated With LASER in the Treatment of Tooth Sensitivity After at Home Bleaching
Tooth whitening is a procedure that has been increasingly requested by patients around the world, whether at home or in office bleaching. Tooth sensitivity is the main side effect of bleaching.
- Trial name
- NCT05298059
- Testing
- Laser of low frequncy, CPP-ACPF
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dental Fluorosis
Clinical Evaluation of Different Minimal Invasive Treatment Modalities of Mild to Moderate Dental Fluorosis Using A Visual Analog Scale
This study was conducted for clinical evaluation of the quality of different minimal-invasive treatment modalities and combination treatments in esthetics improvement of mild to moderate fluorosed teeth using two different…
- Trial name
- NCT05051748
- Testing
- Opalescence™ boost™ PF 40%, Opalustre™, MI-Paste Plus®
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Mutans Streptococci, Oral Health
Antimicrobial Effect of Different Pastes on Streptococcus Mutans in Children
This study is a randomized controlled trial involving 127 children ages between 4 and 5 years to investigate the efficacy of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) in reducing Streptococcus mutans (S.
- Trial name
- NCT03526315
- Testing
- CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP)
- Where
- Jordan
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dental Fluorosis
Clinical Evaluation of Dental Fluororsis Treatment Modalities
Background: Various treatment modalities are available to improve esthetics of fluorosed teeth based on its severity. Aim: evaluate the clinical performance of different minimal invasive treatment protocols on mild to moderate…
- Trial name
- NCT05204277
- Testing
- Opalescence™ boost™ PF 40%, Opalustre™, MI-Paste Plus®
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Remineralization
Remineralization Effect of Fluoride Varnishes on Permanent Molars
The aim of this study was to evaluate and compare the efficacy of NaF, NaF with TCP, NaF with CPP-ACP, and NaF with CXP varnishes on newly erupted first permanent molar teeth.
- Trial name
- NCT04124887
- Testing
- Sodium Fluoride, Tricalcium Phosphate, Xylitol-coated calcium and phosphate
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Caries
Modified Atraumatic Restorative Treatment Using CPP ACP
To evaluate the clinical and radiographic success of using Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP) under glass ionomer restorations in atraumatic restorative treatment as a biomimetic approach in pediatric…
- Trial name
- NCT06098911
- Testing
- MI varnish
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Behavior Problem
Tailoring CPP for the Foster Care Setting
The primary objective of this study is to tailor the Chicago Parent Program, an evidence-based parent training program, for the foster care setting and pilot the content in two cohorts of foster and kinship caregivers (Gross et…
- Trial name
- CPP-FC (NCT05856435)
- Testing
- Chicago Parent Program for Foster Care
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Proximal Caries
Effect of Self-Assembling Peptides on the Progression of Non-Cavitated Proximal Caries
The aim of this randomized controlled, double-blinded, split-mouth clinical trial was to evaluate the efficacy of self-assembling peptide P11-4 solution (Curodont™ Repair) with fluoride varnish on the progression of non-cavitated…
- Trial name
- NCT04776785
- Testing
- Curodont™ Repair, MI Varnish™, Profluorid® Varnish
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Gingival Phenotype
Assessment of Gingival Thickness Using Colored Periodontal Probe
the accuracy of different assessment methods of the gingival tissue thickness can be controversial affecting their correct classification and the techniques of gingival tissue management in case of mucogingival problems.
- Trial name
- NCT05706480
- Testing
- colored periodontal probes (CPP), standard periodontal probes (SPP), transgingival sounding with an endodontic file
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Misr International University
Demineralization
Prevention of Enamel Demineralization Using CPP-ACP-NaF Varnish
Sometimes when people wear braces, the combination of dental plaque and diets high in sugar and acids can lead to white spots on the teeth surrounding the braces.
- Trial name
- CPP-ACP (NCT04002232)
- Testing
- CPP-ACP-NaF varnish
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Parenting, Parenting Intervention
Resilient, Engaged, and Connected Study
Purpose of this study is to test the effectiveness and implementation of an evidence-based parenting intervention for improving parenting and school outcomes in a sample of 4-5-year-old children enrolled in public prekindergarten…
- Trial name
- REC (NCT06197997)
- Testing
- Chicago Parent Program (CPP)
- Where
- 2 sites in United States
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
White Spot Lesion
Remineralization Potential of Curodont Repair Flouride Plus Versus CPP-ACP in Management of White Spot Lesions: Randomized Clinical Trial
The goal of modern dentistry is to manage non-cavitated caries lesions non- invasively through re-mineralization process to prevent the disease progression and improve aesthetics, strength, and function.
- Trial name
- NCT04245787
- Testing
- Self assembling peptide with fluoride
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Sensitivity, Hypersensitivity
A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH
Dentin hypersensitivity (DH) is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects".
- Conditions
- Dentin Sensitivity, Hypersensitivity, Cervical Lesion
- Trial name
- NCT06463938
- Testing
- Active comparator, Experimental group, Combination of laser and paste
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Molar Incisor Hypomineralization
Accuracy of Spectrophotometry in Hypomineralized Lesions Treated With CPP-ACPF Dental Mousse: Clinical Study
MIH is a condition with considerable prevalence in the child population. This structural defect, represented by a change in the color of the enamel, can be accompanied by structural loss and great sensitivity.
- Trial name
- ASHLTDMCS (NCT06330272)
- Testing
- Application of dental mousse based on CPP-ACPF
- Where
- Brazil
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Meire Coelho Ferreira
White Spot Lesion of Tooth
Caries Prevention Potential of Pearl Powder Versus CPP-ACP on Enamel White Spot Lesions
to evaluate the caries prevention potential of pearl powder against CPP-ACP in enamel white spot lesions.
- Trial name
- NCT03973554
- Testing
- pearl powder, CPP-ACP
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ruba Alaa El Din Adel El Damarisy
Chronic Pelvic Pain Syndrome, Pelvic Congestive Syndrome
Development of a Patient-reported Outcome Measure for Women With Chronic Pelvic Pain
The purpose of this study is to develop a patient questionnaire that can be utilized to assess the benefit of treatments of chronic pelvic pain in research studies.
- Trial name
- PROM for CPP (NCT06083597)
- Testing
- Qualitative interview
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Caries,Dental, Remineralization
Remineralization Efficacy of Gum Arabic Varnish.
The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.
- Conditions
- Caries,Dental, Remineralization, White Spot Lesion
- Trial name
- NCT04422860
- Testing
- Gum Arabic varnish, Proflourid Varnish,VOCO, MI Varnish,GC Japan Inc.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries,Dental
The Effect of Casein Phosphopeptide Amorphous Calcium Phosphate on Affected Dentine
Teeth selected for intervention with Atraumatic Restorative Treatment will receive Glass Ionomer restorations (control) or MI varnish (test) before receiving the Glass Ionomer restoration
- Trial name
- NCT04303767
- Testing
- Casein phosphopeptide amorphous calcium phosphate, Atraumatic restorative treatment
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman