Clinical trials: CRC
Colorectal Cancer
Interventions to Improve Colon Cancer Screening in Poor Rural Iowa Counties
The goal of the study is to conduct a randomized clinical trial to test several office-based strategies for improving colon cancer screening among individuals who are regular patients at 16 family practice physician offices in…
- Trial name
- NCT01477814
- Testing
- Physician chart reminder, chart reminder, educational mat'ls, FIT, CR,ed mat'ls, FIT, phone call
- Where
- United States
- Volunteers
- 743 people, healthy volunteers welcome
- Sponsor
- Barcey T. Levy
Second Primary Colorectal Cancer
Impact of 10 Different Prior Cancer History on Survival of Patients Who Underwent Surgery for Second Primary Colorectal Cancer: a Population-based Cohort Study
In this study, the investigators collected data with the SEER*Stat software version 8.4.1 (accession number: 20377-Nov2021). The patients with confirmed diagnoses of CRC (site code C18.0-20.9 and C26.0) between 2004 and 2013 were…
- Trial name
- NCT06189547
- Testing
- different prior cancer history type
- Where
- China
- Volunteers
- 82,770 people, healthy volunteers welcome
- Sponsor
- Guangzhou Medical University
Recurrent or Metastatic Colorectal Cancer
Combination of Nelmastobart and Capecitabine Therapy in Metastatic Colorectal Cancer
This is an open-label clinical trial aimed at evaluating the safety and efficacy of the combination treatment of nelmastobart with capecitabine in patients diagnosed with metastatic or recurrent colorectal cancer.
- Trial name
- NCT05990543
- Testing
- Nelmastobart and Capecitabine
- Where
- South Korea
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Colorectal Cancer
RCT of Air Insufflation Versus Water Infusion Colonoscopy
Compared with the conventional (air) method, patients examined by the study (water) method have lower pain scores and require less medication but have similar cecal intubation rate and willingness to repeat future colonoscopy.
- Trial name
- NCT00785889
- Testing
- water infusion colonoscopy
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- East Bay Institute for Research and Education
Metastatic Colorectal Cancer, Non Small Cell Lung Cancer Metastatic
Pharmacokinetic Characteristics, Safety, Tolerability and Immunogenicity of LY01008 and Avastin in Healthy Chinese Male Subjects
This is a randomized, double-blind, single-dose, parallel-group study comparing pharmacokinetic characteristics, safety , tolerability and immunogenicity of LY01008 (Recombinant Humanized Anti-Human Vascular Endothelial Growth…
- Conditions
- Metastatic Colorectal Cancer, Non Small Cell Lung Cancer Metastatic, Non Small Cell Lung Cancer Recurrent
- Trial name
- NCT05110118
- Testing
- LY01008, Avastin
- Where
- China
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Shandong Boan Biotechnology Co., Ltd
Pneumonia, Pneumococcal, Diabetes Mellitus
Text Message-Based Nudges Prior to Primary Care Visits to Increase Care Gap Closure
Primary care visits are a key aspect of clinical care focused on helping patients to close care gaps related to preventive care such as vaccination, diabetes testing, statin therapy and cancer screening.
- Conditions
- Pneumonia, Pneumococcal, Diabetes Mellitus, Breast Cancer, Colorectal Cancer
- Trial name
- NCT05799976
- Testing
- Text message nudge
- Where
- United States
- Volunteers
- 29,334 people, healthy volunteers welcome
- Sponsor
- Mitesh Patel
Human Papillomavirus, Human Immunodeficiency Virus
Increasing Uptake of Evidence-Based Screening Services Through CHW-led Multi-modality Intervention
The purpose of this research study is to determine the best way to increase screening for cervical cancer, colorectal cancer, HIV, and Hepatitis C among under screened Hispanic, Haitian and African-American individuals in…
- Conditions
- Human Papillomavirus, Human Immunodeficiency Virus, Hepatitis C, ColoRectal Cancer
- Trial name
- NCT02970136
- Testing
- OraQuick Swab, Fecal Immunochemical Test, OraQuick Fingerstick
- Where
- United States
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- University of Miami
Colorectal Cancer, Colorectal Neoplasms
Longitudinal Performance of Epi proColon
This study will evaluate longitudinal performance of Epi proColon with respect to test positivity, longitudinal adherence to Epi proColon screening, adherence to follow-up colonoscopy and diagnostic yield, as well as assay…
- Trial name
- PERT (NCT03218423)
- Testing
- Epi proColon
- Where
- 6 sites in United States
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Epigenomics, Inc
Colorectal Cancer, Healthy, no Evidence of Disease
Narrative or Fact-Based Videos in Increasing Colorectal Cancer Screenings in African American Communities
This randomized clinical trial studies narrative or fact-based videos in increasing colorectal cancer screenings in African American communities.
- Trial name
- NCT02100254
- Testing
- behavioral intervention
- Where
- 2 sites in United States
- Volunteers
- 1,310 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Metastatic Colorectal Cancer
Fruquintinib DDI Study With P-gp and BCRP Substrates
Fruquintinib DDI Study with P-gp and BCRP Substrates
- Trial name
- NCT05368805
- Testing
- Fruquintinib, Dabigatran Etexilate, Rosuvastatin
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hutchmed
Colorectal Cancer
Increasing Colorectal Cancer Screening Uptake With a Patient Navigator
Patients who receive tailored navigation (consisting of a letter and patient navigation services) and get screened will be significantly greater than the control group who receives treatment as usual.
- Trial name
- NCT01506687
- Testing
- Health counselling by nurse navigator, Usual primary care counselling
- Where
- Canada
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Cancer Care Ontario
Colorectal Cancer
Participatory Research to Advance Colon Cancer Prevention
The overall goal of this study is to test strategies to raise rates of colorectal cancer screening among the Latino population in a federally qualified health center that operates multiple clinics.
- Trial name
- PROMPT (NCT03167125)
- Testing
- Automated Prompts, Automated Plus Live Prompts
- Where
- United States
- Volunteers
- 27,580 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Inflammatory Bowel Disease, Colorectal Cancer
Intestinal Microbiota and Colorectal Cancer in Inflammatory Bowel Disease
Build a collection of fecal microbiota in order to determine the characteristics of gut microbiota associated with colorectal cancer in Inflammatory bowel disease (IBD).
- Trial name
- DYSCOLIC (NCT02726243)
- Where
- France
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Colorectal Cancer, Colorectal Neoplasms
Exploring the Risk Factors for Colorectal Cancer in Our General Population Using Asian Pacific Screening Score: a Survey From Pakistan
In Pakistan, due to the lack of a National based cancer registry exact number of CRC cases is unknown. However, minimal data that is present in literature shows an increase in CRC cases with a concerning increase in incidence in…
- Trial name
- NCT05617378
- Where
- Pakistan
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Laparoscopic Colorectal Cancer Surgery
Effect of Intrathecal Morphine on Quality of Recovery After Laparoscopic Colorectal Cancer Surgery
Colorectal cancer is the second most common tumor in women and the third most common tumor in men, accounting for approximately 10% of tumors diagnosed and tumor-related deaths worldwide each year.
- Trial name
- NCT06636864
- Testing
- Intrathecal morphine, Intrathecal saline injection, TAPB
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Colorectal Cancer, Healthy, no Evidence of Disease
Genetic Epidemiology Risk Assessment Program or Usual Care in Colorectal Cancer Screening for Healthy Participants
RATIONALE: The Genetic Epidemiology and Risk Assessment program may be more effective than usual care in increasing the number of healthy participants who regularly receive screening for colorectal cancer.
- Trial name
- NCT00478309
- Testing
- counseling intervention, educational intervention
- Where
- United States
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Colorectal Carcinoma
Cancer Communication Within Hispanic Social Networks
This trial examines cancer communication within Hispanic social networks. Hispanics have the lowest colorectal cancer screening rate of any major ethnic group and health interventions are crucially needed among Hispanics.
- Trial name
- NCT04444232
- Testing
- Media Intervention, Survey Administration
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Improving Fecal Immunochemical Test (FIT) Completion Rates
Behavioral Nudge in Colorectal Cancer Screening
The purpose of this study is to evaluate if a behavioral nudge principle known as social norm driver can be implemented to improve fecal immunochemical test (FIT) completion rates for patients' age 45-75 years old due for…
- Trial name
- NCT06796049
- Testing
- Information pamphlet + social norm driver, Information pamphlet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Colo-rectal Cancer
The United States Healthy Living Study
The purpose of this study is to pilot test the efficacy of a patient-centered, tailored message intervention delivered via virtual human technology for increasing colorectal cancer (CRC) screening within guidelines.
- Trial name
- NCT03867409
- Testing
- message delivered via virtual technology
- Where
- United States
- Volunteers
- 2,105 people, healthy volunteers welcome
- Sponsor
- University of Florida
Caregiver Burden, Colorectal Cancer
LEgal Guidance and AdvocaCY for CAREgivers (LEGACY CARE): A Pilot Clinical Trial for Caregivers of Persons With Colorectal Cancer
This is a single center single-arm, pilot study of proactive and early connection with free legal care services for patient-caregiver dyads affected by colorectal cancer to assess the feasibility, acceptability, and preliminary…
- Conditions
- Caregiver Burden, Colorectal Cancer, Legal Intervention
- Trial name
- NCT07153016
- Testing
- Legal Services
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota