Clinical trials: CRP
Glucose Intolerance
C-reactive Protein and Endothelial Dysfunction in Women With Glucose Intolerance
The goal of this study is to determine whether markers of vascular inflammation (such as c-reactive protein) can predict endothelial dysfunction (as measured by flow-mediated dilation) in postmenopausal women with glucose…
- Trial name
- NCT00589355
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Yale University
Inflammation
Effect of Anatabine on Elevated Blood Levels of C-reactive Protein
The investigators are studying a dietary supplement called anatabine in a lozenge form named RCP006. The main purpose of this study is to evaluate the effects of this dietary supplement on normal human inflammatory function.
- Trial name
- NCT01607619
- Testing
- Anatabine
- Where
- 3 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Roskamp Institute Inc.
Type 2 Diabetes Mellitus With Periodontal Complication, Inflammation
Taking Out All Teeth and Replacing Them With Dentures That Rest on Implants in People With Type 2 Diabetes
Gum disease and type 2 diabetes are common chronic diseases that affect each other. Diabetes is increasing, especially in Pakistan. People with diabetes have a greater risk for gum disease.
- Conditions
- Type 2 Diabetes Mellitus With Periodontal Complication, Inflammation, Dental Implant Failed
- Trial name
- NCT01774942
- Testing
- Procedure/Surgery
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Hypercholesterolemia, Vitamin D Deficiency
Effects of Vitamin D on Lipids
The purpose of this study is to examine whether oral vitamin D supplementation in people with inadequate vitamin D concentrations will lower LDL-cholesterol and total cholesterol concentrations.
- Trial name
- NCT00723385
- Testing
- Vitamin D (1000 or 2000 IU/day)
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Osteoarthritis
Efficacy Test of Curcuminoid Standardized Turmeric Capsules to Improving Inflammatory Biomarkers in Osteoarthritis Genu
The goal of this clinical trial is to learn if Curcuminoid Standardized Turmeric Capsules works to treat Osteoarthritis Genu in adults. It will also learn about the safety of Curcuminoid Standardized Turmeric Capsules.
- Trial name
- ETCS (NCT07183215)
- Testing
- Curcuminoid Standardized Turmeric Capsules
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Gadjah Mada University
Pneumonia, Bacterial
Diagnostic Accuracy of Infection Biomarkers in the Initial Investigation of Patients With Suspected Pneumonia
The aim of this study is to investigate the diagnostic and prognostic value of C-reactive protein (CRP), serum procalcitonin (PCT) and soluble urokinase plasminogen activator receptor (suPAR) in the initial investigation of…
- Trial name
- NCT04652167
- Testing
- PCT, suPAR, Standard care
- Where
- Denmark
- Volunteers
- 411 people
- Sponsor
- University of Southern Denmark
Healthy Volunteers, C-Reactive Protein
A Study of LY5625575 in Healthy Participants and in Participants With Inflammation (Elevated C-Reactive Protein)
The main purpose of this study is to evaluate the safety and tolerability of LY5625575 in healthy participants (including Japanese and Chinese) and in participants with high levels of a marker for inflammation (C-reactive…
- Trial name
- NCT07801300
- Testing
- LY5625575
- Where
- 2 sites in United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Cardiovascular Disease
High Dose and Low Dose of Atorvastatin in Patients With Unstable Angina and NSTEMI (Non ST Elevation MI)
The aim of this study is to compare the effect of high dose and low dose of Atorvastatin in reduction level of C-reactive protein (CRP) in patients with unstable angina and NSTEMI (Non ST Elevation MI) attending Shahid Mohammadi…
- Trial name
- NCT01306565
- Testing
- Low dose Atorvastatin, High dose atorvastatin
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Hormozgan University of Medical Sciences
Hashimoto Thyroiditis, Subacute Thyroiditis
Colchicine for Autoimmune and Subacute Thyroiditis
Thyroiditis includes inflammatory thyroid disorders such as Hashimoto's thyroiditis and subacute thyroiditis. These conditions may cause thyroid pain, neck tenderness, elevated inflammatory markers, thyroid dysfunction, fatigue…
- Conditions
- Hashimoto Thyroiditis, Subacute Thyroiditis, Thyroiditis
- Trial name
- COLTHYR (NCT07571681)
- Testing
- colchicine, Prednisolone, NSAID
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 300 people
- Sponsor
- Mansoura University
HIV Infections, Inflammatory Markers
Efficacy and Safety of Low-Dose Colchicine on Surrogate Markers of Cardiovascular Events in People Living With HIV Receiving Antiretroviral Therapy
In a double-blind, randomized controlled trial, we assigned PLWH receiving ART without a history of cardiovascular events to received colchicine 0.6 mg once daily or placebo.
- Conditions
- HIV Infections, Inflammatory Markers, Colchicine Adverse Reaction
- Trial name
- NCT05168137
- Testing
- Low-dose colchicine
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Mahidol University
Covid19
Study of CRP, Ferritine and D-Dimer in Covid-19 Patients Admitted To Respiratory ICU in Assuit University Hospitals
To Study serum CRP, D-dimer and serum ferritin in adult patients with COVID-19 for the presence or absence of clinically validated definitions of mortality, severe COVID-19, ARDS, and intensive care unit (ICU) care.
- Trial name
- NCT05102695
- Testing
- Serum CRP , ferritine and d-dimer
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
Recurrent Pericarditis
Therapy Management in Patients Treated With Anakinra Due to Recurrent Pericarditis
To determine the utility of serial cardiac magnetic resonance (CMR) imaging for guidance of therapy management in patients treated with anakinra due to recurrent pericarditis (RP), compared with c-reactive protein (CRP) assay…
- Trial name
- NCT06071156
- Testing
- Anakinra
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Vitamin D Deficiency
Effect of Vitamin D Supplementation on Health of Low Birth Weight Infants
The purpose of this study is to determine whether a weekly supplement of vitamin D to low birth weight term infants will reduce their mortality and hospital admissions and improve their immunity.
- Trial name
- DIVIDS (NCT00415402)
- Testing
- Vitamin D3
- Where
- India
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Delhi University
Periodontitis, Periodontitis Stage I
Hypochlorous Acid in Non-Surgical Periodontal Therapy
Periodontitis is a chronic inflammatory disease associated with dental plaque and characterized by the progressive destruction of the tooth-supporting tissues.
- Conditions
- Periodontitis, Periodontitis Stage I, Periodontitis Stage II
- Trial name
- NCT07712627
- Testing
- Hypochlorous Acid Application, Scaling and Root Planing (SRP) with Purified Water
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ataturk University
Clostridium Difficile Colonisation, Impact of Enteral Probiotics on Certain Lab Parameters
Probiotics for Reduction of Infections With Clostridium Difficile in Critically Ill Patients
Symptoms of Clostridium difficile infection is almost always induced as a complication to the use of antibiotics. Most ICU patients are given antibiotics.
- Trial name
- ProbiEnt (NCT01687543)
- Testing
- L. plantarum 299 and L. plantarum 299v (+maltodextrin), Maltodextrin
- Where
- 4 sites in Sweden
- Volunteers
- 25 people
- Sponsor
- Region Skane
Procalcitonin, Infection
Procalcitonin as a Prognostic Predictor in Patients With Acute Infectious Disease Hospitalized in the Internal Medicine Department.
Procalcitonin is a well-known biomarker used to distinguish between bacterial and viral infections, assess a patient's risk category, and serve as a prognostic indicator.
- Conditions
- Procalcitonin, Infection, Internal Medicine Patients
- Trial name
- NCT07770334
- Testing
- No Interventions
- Volunteers
- 1,000 people
- Sponsor
- Barzilai Medical Center
Diabetes Mellitus, Insulin-Dependent, Hypercholesterolemia
Statins in Children With Type 1 Diabetes and Hypercholesterolemia
Children with type1 diabetes (T1DM) have increased risk for cardiovascular disease (CVD) due to chronic increase in the blood sugars and inflammation.
- Trial name
- NCT01236365
- Testing
- Atorvastatin
- Where
- 5 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Fever Malaria
Clinical Evaluation of the STANDARD™ Q Malaria/CRP Duo Test
The aim of this study is to assess the clinical performance (sensitivity, specificity, positive and negative predictive values) of the STANDARD™ Q Malaria/CRP Duo Test when used by health care workers (HW) in a point of care…
- Trial name
- NCT04791800
- Testing
- Malaria/CRP combination test
- Where
- India
- Volunteers
- 1,808 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
End Stage Kidney Disease (ESKD)
A Phase 1b Study to Evaluate the PK of CSL300 (Clazakizumab) in Chinese Subjects With End Stage Kidney Disease (ESKD)
This is a phase 1b, partial-blind (Sponsor unblinded), randomized, multicenter, placebo-controlled study. The primary objective of this study is to evaluate the pharmacokinetics (PK) of CSL300 after single and multiple doses in…
- Trial name
- NCT07619820
- Testing
- CSL300
- Where
- China
- Volunteers
- 24 people
- Sponsor
- CSL Behring
Periodontal Diseases
Evaluation of Salivary Biomarker Levels of Individuals With Different Periodontal Diseases
The aim of this study is; detection of leucine rich α-2 glycoprotein1 (LRG1), c-reactive protein (CRP) levels in saliva samples of periodontally healthy, gingivitis and periodontitis patients and the possible correlation between…
- Trial name
- NCT05774925
- Testing
- saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University