Clinical trials: CT
Coronary Microvascular Disease, Coronary Artery Disease
A Non-invasive Index of Microciculatory Resistance
Coronary artery microvascular disease (CMVD) lacks reliable and non-invasive quantitative diagnosis methods. Improving coronary microcirculation has become one of the main goals of coronary heart disease treatment.
- Trial name
- NCT04554004
- Testing
- CCTA, CT-MPI, DSA, FFR
- Where
- China
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou
Heartburn
A Study to Assess the Bioequivalence of Famotidine Chewable Tablets and Film-Coated Tablets (0208-144)
This study will determine whether the CT formulation of famotidine taken with and without water is bioequivalent to the FCT formulation.
- Trial name
- NCT00945750
- Testing
- Famotidine FCT, Famotidine CT
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Lung Cancer, Lung Neoplasms
Liquid Biopsy-Based Pre-Screening to Streamline LDCT Lung Cancer Screening in High-Risk Individuals
This study evaluates the feasibility and cost-effectiveness of using a blood-based liquid biopsy assay as a pre-screening tool before low-dose CT (LDCT) for lung cancer screening.
- Conditions
- Lung Cancer, Lung Neoplasms, Early Lung Cancer Detection, Cancer Screening
- Trial name
- NCT07358715
- Testing
- Liquid Biopsy (SPOT-MAS Assay), Exosome-Based Liquid Biopsy Assay, Low-Dose CT Thorax (LDCT)
- Where
- Singapore
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Neuroendocrine Tumors
Imaging of Patients With Known or Suspected Somatostatin Receptor Positive Neuroendocrine Tumors Using Cu64-DOTATATE
This is an open-label, single-dose, single-arm, single-center imaging study using DOTATATE peptide, labelled with the 64Cu tracer.
- Trial name
- NCT03673943
- Testing
- 64Cu-DOTATATE
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Radiomedix, Inc.
Renal Artery Stenosis, Kidney Diseases
Renal Artery Contrast-Free Trial
This study will compare the results of a clinically ordered abdominal CT angiography to a research non-contrast MR angiogram (MRA).
- Conditions
- Renal Artery Stenosis, Kidney Diseases, Hypertension
- Trial name
- REACT (NCT01576835)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Central Coast Cardiovascular Research
Maxillary Cyst
Deproteinized Bovine Bone in Alveolar Bone Critical Size Defect (>2cm) Secondary to Cyst Removal
The aim of this study was to evaluate the effect of the use of deproteinized bovine bone as a filler material of critical-sized (diameter >=20 mm) bony defects derived from the excision of maxillary and mandibular cysts.
- Trial name
- NCT02612740
- Testing
- Deproteinized bovine bone, granules of deproteinized bovine bone (Bio-Oss)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Adult-acquired Flatfoot Disorder (AAFD)
Weightbearing Assessment of Tarsal Instability
The purpose of this study is to compare the average joint motion and joint axis orientation of the hindfoot bones between patients diagnosed with adult-acquired flatfoot disorder (AAFD) and a control group of patients without…
- Trial name
- WBCT (NCT01868789)
- Testing
- Weightbearing CT
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Orthopedic Foot and Ankle Center, Ohio
Non-Hodgkin Lymphoma
Early FDG PET/CT Imaging as a Measure of Response in Patients With Non-Hodgkin Lymphoma on Lenalidomide
Adult patients with non-Hodgkin lymphoma who will be treated with lenalidomide will undergo FDG PET/CT scan as an early evaluation of response to therapy. Changes in FDG uptake will be correlated response and long term outcomes.
- Trial name
- NCT03065790
- Testing
- 2-Deoxy-2-[18F]fluoro-D-glucose (FDG)
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Aging, Inflammation
Relationship Between Thoracic Aortic Structure Assessed B PET/CT Scan and Arterial Stiffness in Elderly Patients
The purpose of this study is to determine the relationship between thoracic aortic inflammation and arterial stiffness in elderly patients.
- Trial name
- FICTEP (NCT01963221)
- Testing
- fludeoxyglucose(18f), blood sample, cardiac and aortic magnetic resonance imaging
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Emergency Medical Services, Critical Illness
Development of an AI-based Emergency Imaging Multi-Disease Rapid Joint Screening System
Introduction: Early and rapid diagnosis of etiology is often an important part of saving the lives of patients in emergency department.
- Conditions
- Emergency Medical Services, Critical Illness, Emergency Service, Hospital, Machine Learning
- Trial name
- Al-MDS (NCT05974163)
- Testing
- radiomic of CT
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Advanced Gastroenteropancreatic Neuroendocrine Tumor
Gallium (68Ga) Edotreotide PET/CT for Imaging Patients With Gastrointestinal Pancreatic Neuroendocrine Tumors
This is a single-arm imaging study using DOTATOC peptide, labelled with the Gallium (68Ga) tracer.
- Trial name
- NCT06091748
- Testing
- 68Ga-DOTATOC
- Where
- China
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Impacted Third Molar Tooth
Assessment of Vertical Pattern in Correlation With Third Molar Inclusion : A 3D CBCT Analysis
The objective is to compare the sagittal and vertical skeletal parameters of patients with an impacted third molar. Patients will be analyzed according to their skeletal characteristics: skeletal class (sagittal direction) and…
- Trial name
- NCT06320665
- Testing
- Radiographic measurement
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Vasospastic Angina
Multidetector Coronary CT In Vasospastic Angina
The purpose of this study is to compare the extent of coronary vessel stenosis between coronary spasm-induced angina attacks (named vasospastic angina, VSA) patients and health volunteers by multi-detector computed tomography…
- Trial name
- NCT02180971
- Testing
- Positive CAG with EG test, Negative CAG with EG test
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dong-A University
Hill Sachs
Assessment of Weber Humeral Derotational Osteotomy Using CT Scan
Subjects who have had the Weber osteotomy for Hill-Sachs lesions will have CT of Both shoulders. Amount of rotation in operative shoulder will be compared to contralateral. QOL will be assessed
- Trial name
- NCT00358904
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Radiation Protection
Enhancement and Restoring of Low Dose Abdominal CT Images
Through the rapid growth of multislice Computer Tomography (CT) imaging, radiation protection has become a major issue in the radiological community.
- Trial name
- NCT01059032
- Testing
- Using a 3 dimentional post processing filter
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lars Borgen
Atrial Fibrillation
Non - Invasive Evaluation of the Left Atrium Anatomy and Function
The aim of the study is to evaluate the accuracy and reproducibility of the left atrium (LA) anatomy and function in different populations and in patients with atrial fibrillation who have undergone cryoballoon ablation.
- Trial name
- NCT03551158
- Testing
- Echocardiography
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Tumor, Solid, Positron-Emission Tomography
68Ga-FAPI-RGD PET/CT for Dual Integrin αvβ3 and FAP-targeted Imaging in Patients With Various Types of Cancer and Compared With 18F-FDG
As a new dual receptor (integrin αvβ3 and FAP) targeting PET radiotracer, 68Ga-FAPI-RGD is promising as an excellent imaging agent applicable to various cancers.
- Trial name
- NCT05543317
- Testing
- 18F-FDG PET/CT, 68Ga-FAPI-RGD PET/CT
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Xiamen University
Head and Neck Squamous Cell Carcinoma
HN-QUEST: A Study of Head and Neck Imaging Biomarkers
This is a multi arm, single center, investigator initiated study to investigate online adaptive radiotherapy and biomarker development in patients with newly diagnosed HNSCC (Head and Neck Squamous Cell Carcinoma) receiving…
- Trial name
- HN-Quest (NCT05919290)
- Testing
- MRI
- Where
- Canada
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Healthy
To Compare the PK and Safety of Omalizumab (CT-P39, EU-approved Xolair, and US-licensed Xolair) in Healthy Subjects
A Phase 1, Randomized, Double-blind, Three-arm, Parallel Group, Single-dose Study to Compare the Pharmacokinetics and Safety of Three Formulations of Omalizumab (CT-P39, EU-approved Xolair, and US-licensed Xolair) in Healthy…
- Trial name
- NCT04018313
- Testing
- CT-P39, EU-approved Xolair, US-licensed Xolair
- Where
- 2 sites in Australia
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Celltrion
Clinical Decision-Making
Key Information Can Influence Clinician Ordering of Brain CTs
The frequency of head computed tomography (CT) imaging for mild head trauma patients has raised safety and cost concerns. Validated clinical decision rules exist in the published literature and on-line sources to guide medical…
- Trial name
- NCT03449862
- Testing
- Simulation-based clinical decision on brain CT ordering
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Clemson University