Clinical trials: CTS, open to volunteers
Charcot-Marie-Tooth Neuropathy Type 1A, Hereditary Transthyretin Amyloid Neuropathy
Longitudinal Quantitative Neuromuscular MRI in Neuropathic Patients
The pathophysiological process common to neuropathies is fatty replacement of muscle tissue, more commonly known as intramuscular fat fraction (F.F).
- Conditions
- Charcot-Marie-Tooth Neuropathy Type 1A, Hereditary Transthyretin Amyloid Neuropathy, Acquired Demyelinating Neuropathy
- Trial name
- IMAGINERV (NCT06845644)
- Testing
- Quantitative neuromuscular MRI, Neuromuscular ultrasound
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Transthyretin Amyloid Cardiomyopathy
Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
This multicenter pilot study will enroll adult participants with a confirmed clinical diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM) and heart failure (HF) controls with documentation within the past 2 years that…
- Trial name
- NCT07690436
- Where
- 20 sites in United States, Germany and 3 more
- Volunteers
- 500 people
- Sponsor
- AstraZeneca
Carpal Tunnel Syndrome (CTS), Carpal Tunnel Surgery
Carpal Tunnel Release Efficacy Trial
Background Carpal tunnel syndrome (CTS) is a prevalent condition that affects 2.7% of the population, especially women. It arises due to compression of the median nerve in the wrist and is linked to factors like diabetes…
- Trial name
- FOCUS (NCT06934187)
- Testing
- Carpal tunnel release
- Where
- Finland
- Volunteers
- 96 people
- Sponsor
- Kuopio University Hospital
Carpal Tunnel, Transthyretin Amyloidosis
Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament Biopsy
Transthyretin amyloidosis (ATTR) is an underdiagnosed condition that can present early as carpal tunnel syndrome, sometimes preceding cardiac involvement by several years.
- Trial name
- ATTR2026 (NCT07644325)
- Testing
- Annular ligament biopsy
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Clinique Saint Jean, France
Cardiac Amyloidosis, Transthyretin Amyloidosis
ATTRACT-52: Primary Care Cardiac Amyloidosis Screening in Ordu, Turkey
Cardiac amyloidosis is a progressive infiltrative cardiomyopathy, most commonly related to transthyretin (ATTR) misfolding. Although considered rare, emerging data suggest higher prevalence in specific regions, including the…
- Trial name
- ATTRACT-52 (NCT07238426)
- Where
- Turkey (Türkiye)
- Volunteers
- 800 people
- Sponsor
- Kotyora Family Medicine Health Management and Education Association
Scapholunate Advanced Collapse (SLAC), Scapholunate Crystalline Advanced Collapse (SCAC)
The KinematX Midcarpal Total Wrist Arthroplasty Registry
The goal of this observational study is to learn about functional and patient reported outcomes in patient undergoing total wrist replacement with the KinematX total wrist replacement study.
- Conditions
- Scapholunate Advanced Collapse (SLAC), Scapholunate Crystalline Advanced Collapse (SCAC), Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC), Carpal Tunnel Syndrome (CTS)
- Trial name
- NCT05719935
- Testing
- KinematX total wrist arthroplasty system
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Extremity Medical
Carpal Tunnel Syndrome (CTS), Hyperthermia
Analysis of Hyperthermia as a Complementary Treatment to Evidence-based Clinical Intervention in Subjects With Carpal Tunnel Syndrome:
This project aims to analyze the use of hyperthermia within a treatment protocol for Carpal Tunnel Syndrome (CTS), as well as to determine the difference between two and three sessions per week.
- Conditions
- Carpal Tunnel Syndrome (CTS), Hyperthermia, Frequency of Therapy
- Trial name
- NCT06942273
- Testing
- hyperthermia, physical exercise, splint
- Volunteers
- 160 people
- Sponsor
- University of Malaga
Carpal Tunnel Syndrome (CTS) Post-burn
Hand Function Outcome After the Application of Transfer Energy Capacitive and Resistive on Post-burn Patients Presented With Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is a common entrapment neuropathy that can develop as a secondary complication following deep burns involving the hand or wrist.
- Trial name
- NCT07660328
- Testing
- Transfer Energy Capacitive and Resistive (TECAR) [ SMART TECAR }, Standard Hand Rehabilitation [ US }
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Transthyretin Amyloidosis, Heart Failure
Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF
Recent studies have shown that transthyretin amyloidosis (ATTR) can sometimes cause a type of heart failure where the pumping function of the heart is normal, also known as Heart Failure with Preserved Ejection Fraction (HFpEF)…
- Conditions
- Transthyretin Amyloidosis, Heart Failure, Heart Failure, Diastolic, Amyloidosis
- Trial name
- TTRinHFpEF (NCT05577819)
- Testing
- 99mTc-pyrophosphate Scintigraphy
- Where
- United States
- Volunteers
- 515 people
- Sponsor
- Massachusetts General Hospital
Carpal Tunnel Syndrome (CTS)
Electrophysiological and Functional Recovery After Carpal Tunnel Release
Carpal tunnel syndrome occurs when the median nerve is compressed at the wrist. It can cause pain, numbness, tingling, reduced hand strength, and difficulty performing daily activities.
- Trial name
- ELECTRO-CTS (NCT07803939)
- Testing
- Primary Carpal Tunnel Release Surgery
- Volunteers
- 100 people
- Sponsor
- Istanbul Medipol University Hospital
Ultrasonography, Diagnosis
Added Value of Ultrasonography in the Diagnosis, Management, and Follow-Up of Carpal Tunnel Syndrome
This study aims to assess the ultrasound (US) and nerve conduction studies (NCS) as a tool for diagnosis, treatment planning and follow-up of patients with carpal tunnel syndrome (CTS).
- Conditions
- Ultrasonography, Diagnosis, Management, Follow-Up
- Trial name
- NCT06834061
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Transthyretin Amyloidosis With Cardiomyopathy
DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting
The purpose of this study is to: Describe the clinical characteristics of adult patients with transthyretin-mediated amyloidosis with cardiomyopathy (ATTR-CM) treated with vutrisiran in routine clinical care Describe treatment…
- Trial name
- DemonsTTRate (NCT07358078)
- Where
- 27 sites in United States, Germany and 1 more
- Volunteers
- 2,000 people
- Sponsor
- Alnylam Pharmaceuticals
Cardiac Amyloidosis, Transthyretin Amyloidosis
Retrospective Identification of Scintigraphic Cardiac Amyloidosis (RISCA)
This study aims to determine the positive predictive value of incidental cardiac uptake on bone scintigraphy for diagnosing transthyretin cardiac amyloidosis, in patients who underwent scintigraphy for reasons other than…
- Trial name
- RISCA (NCT06921408)
- Volunteers
- 57 people
- Sponsor
- University Hospital, Lille
Carpal Tunnel Syndrome (CTS), Kinesio Taping
Effectiveness of Kinesiotaping and Peloidotherapy in Carpal Tunnel Syndrome
Patients diagnosed with mild and moderate idiopathic CTS will be randomly divided into three groups. Patients who received 15 sessions of peloid therapy along with a home exercise program will constitute the first group.
- Conditions
- Carpal Tunnel Syndrome (CTS), Kinesio Taping, Exercise, Pain Management
- Trial name
- NCT06977321
- Testing
- Kinesiotaping, Peloidotherapy, Home exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Carpal Tunnel Syndrome (CTS)
Low-Level Laser Therapy for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy, caused by compression of the median nerve within the carpal tunnel at the wrist.
- Trial name
- NCT07788248
- Testing
- Low-Level Laser Therapy (LLLT), Paraffin Bath Therapy, Standard Conservative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Carpal Tunnel Syndrome (CTS) in Breast Cancer Patients
Laser Acupuncture on Carpal Tunnel Syndrome .
The study will be carried out on a total number of fifty-four females with age ranged 40 - 60 years old suffering from CTS post mastectomy ,the patients will be randomly assigned into two groups equal in number (27 patients for…
- Trial name
- NCT07405008
- Testing
- LASER acupuncture technique, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Carpal Tunnel Syndrome
Effectiveness of Desensitisation and Pain Neuroscience Education in Patients With Carpal Tunnel Syndrome With Nosiplastic Pain
The aim of our study was to determine the effectiveness of desensitisation and pain neuroscience education in a group of patients with mixed phenotype pain (neuropathic and nosiplastic).
- Trial name
- NCT06635213
- Testing
- Desensitisation, Pain neuroscience education
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kutahya Health Sciences University
Carpal Tunnel Syndrome (CTS)
Effectiveness of Amniotic Membrane Combined With Secretome as an Adjunct to Carpal Tunnel Release Surgery: Evaluation Using the Boston Carpal Tunnel Questionnaire and Electromyography
Carpal Tunnel Syndrome (CTS) is a compressive neuropathy caused by chronic compression of the median nerve within the carpal tunnel, resulting in pain, numbness, tingling, and impaired hand function.
- Trial name
- Secretome CTS (NCT07723313)
- Testing
- Secretome, amniotic membrane, Standard surgery
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- PT. Prodia Stem Cell Indonesia
Carpal Tunnel Surgery
Effect of Progressive Gamified Motor Rehabilitation After Carpal Tunnel Release
Carpal tunnel syndrome is the most common peripheral entrapment neuropathy and may result in sensory and motor impairment, particularly in patients with severe disease and thenar muscle atrophy.
- Trial name
- NCT07899203
- Testing
- gamified motor rehabilitation, conventional physical therapy treatment for patient with carpal tunnel syndrome
- Volunteers
- 40 people
- Sponsor
- Al-Zaytoonah University of Jordan
Carpal Tunnel Syndrome (CTS)
Clinical Efficiency Testing of Extracorporeal Radial and Focused Shock Wave Therapy in Patients With Mild to Moderate Carpal Tunnel Syndrome
The aim of the project is to test the efficacy of extracorporeal shock wave therapy (radial + focused) on clinical outcomes in patients with carpal tunnel syndrome (CTS).
- Trial name
- NCT06912893
- Testing
- radial shock wave therapy, focused shock wave therapy
- Volunteers
- 60 people
- Sponsor
- University Hospital St. Polten