Clinical trials: Caesarean Delivery
Cesarean Section Complications, Hypotension
Can Right Toe Perfusion Index or Pleth Variability Index Predict Spinal Anesthesia Induced Hypotension?
Spinal anesthesia for caesarean section is associated with a decrease in systemic vascular resistance and cardiac output and may cause hypotension in a significant portion of the parturients.
- Conditions
- Cesarean Section Complications, Hypotension, Spinal Anesthesia, Perfusion Index
- Trial name
- NCT03956186
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Cesarean Section Complications, Hemodynamic Instability
Norepinephrine in Caesarian Section
Postspinal hypotension is a frequent maternal complication in caesarian delivery under neuraxial anesthesia which is most commonly treated with the administration of phenylephrine infusion.
- Conditions
- Cesarean Section Complications, Hemodynamic Instability, Foetal Stress
- Trial name
- NCT05264870
- Testing
- Norepinephrine
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Pruritus, Pregnancy Related
Treatment of Pruritus With Intramuscular Promethazine
Neuraxial narcotics are commonly used in obstetric patients for cesarean delivery to help with pain control over the first 24 hours after the surgery.
- Trial name
- NCT04805073
- Testing
- Promethazine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pre-Eclampsia, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Electroencephalographic Effects of Spinal Anaesthesia During Caesarean Delivery in Preeclampsia
Neuraxial anesthesia has been associated with delayed brainstem conduction and decreasing afferent sensory transmission, thereby modifying reticulo-thalamo-cortical mechanisms regulating arousal.
- Trial name
- NCT03917342
- Testing
- EEG measure
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cesarean Section Complications
Mechanical Dilatation of the Cervix at Elective Caesarean Section on Post-operative Morbidity
The study aims to evaluate the effects of cervical dilatation during cesarean section on postoperative maternal morbidity through different clinical parameters.
- Trial name
- NCT05997498
- Testing
- mechanical cervical dilatation
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Beni-Suef University
Tocophobia, Pregnancy Complications
Tokophobia ; Our Clinical Experience
Fear of childbirth, or what has historically been called tokophobia, is often described as a severe fear of birth and pathological fear of childbirth.
- Trial name
- NCT05627336
- Testing
- pregnant women in the 3rd trimester
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Hypothermia, Anesthesia
Electric Warming Mattress to Prevent IPH During LSCS
This study will demonstrate whether an electric warming mattress can reduce the number of patients who get cold and shiver after elective cesarean section.
- Conditions
- Hypothermia, Anesthesia, Obstetric Anesthesia Problems
- Trial name
- ObsIPH (NCT01054209)
- Testing
- Warming with warming mattress
- Where
- United Kingdom
- Volunteers
- 116 people
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Procedural Sedation
Dexmedetomidine and Midazolam Nebulization as Sedation During Cesarean Delivery in Pre-eclampsia
Null hypothesis: There is no difference between the effects of nebulization of dexmedetomidine and midazolam as procedural sedation during cesarean delivery under spinal Anesthesia in pre-eclamptic parturients Alternative…
- Trial name
- NCT04873596
- Testing
- Nebulized dexmedetomidine, Nebulized midazolam
- Where
- Egypt
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Endometrial Diseases
Intrauterine Microbiota During IVF in Patients Affected With Isthmocele.
To evaluate the endometrial and isthmic microbiota in patients with isthmocele after C-Section, and if this microbiota is similar or not with better reproductive outcomes.
- Trial name
- NCT03519763
- Testing
- ultrasound
- Where
- United Arab Emirates
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Placenta Previa
ERAS Protocol for Cesarean Delivery in Women With Placenta Previa
This study aims to evaluate the impact of Enhanced Recovery After Surgery protocols on maternal outcomes patient satisfaction and length of hospital stay following cesarean delivery in women with placenta previa.
- Trial name
- NCT07830914
- Testing
- Enhanced Recovery After Surgery Protocol, Conventional perioperative care
- Volunteers
- 100 people
- Sponsor
- Assiut University
Hypotension
Diastolic Performance and Norepinephrine in Spinal-Induced Hypotension for Cesarean Delivery
Background and rationale: The best agent to prevent spinal-induced hypotension is still uncertain but norepinephrine showed fewer effects on heart rate and cardiac output.
- Trial name
- NORA-CS (NCT04560634)
- Testing
- Norepinephrine, ClearSight®, Edwards Lifescience, Irvine, CA
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cesarean Section Complications
Effect of Autologous Platelet-rich Plasma in Uterine Wound Healing
The aim of this study is to evaluate the efficacy of intramuscular autologus platelet rich plasma on uterine wound healing after primary cesarean section
- Trial name
- NCT03497325
- Testing
- autologus platelet rich plasma
- Where
- Egypt
- Volunteers
- 134 people
- Sponsor
- Ain Shams University
Cesarean Section Complications
B-Lynch Transverse Compression Suture Versus a Sandwich Technique (N&H Technique) for Complete Placenta Previa
Obstetric hemorrhage is estimated to be responsible for about 30% of all maternal deaths and is the leading direct etiology of maternal mortality worldwide .
- Trial name
- NCT03682510
- Testing
- stepwise devascularization, B-Lynch Transverse Compression Suture group, N&H sandwich technique
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Aswan University Hospital
Bowel Ileus, Cesarean Section Complications
Effect of Chewing Gum and Drinking Fennel Tea
Aim: Postoperative ileus after cesarean section is a problem that significantly prolongs hospital stay and increases perioperative costs.
- Trial name
- NCT06403215
- Testing
- Chewing gum group, Fennel tea group, Chewing gum+Fennel tea group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Defect
Comparison of the Therapeutic Effects of VR and VR + Metformin in the Treatment of Cesarean Section Scar Defect
Cesarean section scar defect (CSD) is a novel recognized cause of postmenstrual abnormal uterine bleeding in women. No clinical guidelines have been issued for the management of CSD.
- Trial name
- NCT05205317
- Testing
- Metformin Hydrochloride Sustained-release Tablets, Vaginal repair
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Chorioamnionitis, Pregnancy Complications, Infectious
Closure of Skin in ChorioAmnionitis Research Pilot Study
The purpose of the CSCAR pilot study is to improve the design of a full-scale trial by determining the patient recruitment rate and participation rate.
- Conditions
- Chorioamnionitis, Pregnancy Complications, Infectious, Complications; Cesarean Section, Postoperative Complications
- Trial name
- CSCAR (NCT01988168)
- Testing
- Suture closure, Staples closure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Child Delivery Using an Elective C- Section
Evaluation of the BioWeld1 System as a Method for Surgical Incision Closure
The purpose of this study is to assess the safety and performance of the BioWeld1 System procedure for surgical incision closure of the skin in women scheduled for elective C-section procedure.
- Trial name
- NCT01709240
- Testing
- BioWeld1 System
- Where
- Israel
- Sponsor
- IonMed Ltd
Gastrointestinal Motility and Defaecation Conditions
Early Versus Late Hydration After Cesarean Section (CS)
This study evaluates the effect of early oral hydration on bowel movement after CS, it includes 2 groups: study group participants receive 100 ml water after 1hr from the end of CS, while the others receive water after 6hrs from…
- Trial name
- NCT02630810
- Testing
- Early oral hydration, Delayed oral hydration
- Where
- Egypt
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Cesarean Section Complications
Continuous Intrapartum Support to Reduce Primary Cesarean
The objective of the study was to evaluate the intervention of intrapartum continuous support by a professional nurse with a university degree to reduce the nulliparous, term, singleton, vertex (NTSV) cesarean birth rate, in…
- Trial name
- NCT04086277
- Testing
- Continuous Intrapartum Support
- Where
- Mexico
- Volunteers
- 115 people
- Sponsor
- IMSS Hospital General de Zona 4, Celaya, Guanajauto, Mexico
Gum Chewing, Bowel Function
Gum Chewing And Bowel Motility in Patients Undergoing Cesarean Section. Kasr el Ainy Experience
The aim of the present study was to evaluate the effect of chewing gum on the recovery of bowel function after cesarean section in women.
- Trial name
- RCT (NCT02533830)
- Testing
- sugarless gum, traditional management
- Where
- 2 sites in Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
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