Clinical trials: Caffeine
Wrinkle, Spot Pigmented
Skin Rejuvenation With Topical Extract and Other Nutraceuticals
Hemp extract has been shown in several pre-clinical and clinical studies to have anti-aging effects on the skin through anti-oxidant and anti-inflammatory effects, in addition resveratrol, thyme and caffeine have been shown to…
- Conditions
- Wrinkle, Spot Pigmented, Lines Skin
- Trial name
- NCT05734703
- Testing
- Nutraceutical Topical
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical Life Care Planners, LLC
Caffeine, Placebo
Caffeinated Chewing Gum on Special Forces Performance
The purpose of this project is to investigate the effects of caffeine chewing gum on the cognitive functions and special operations capabilities of special forces.
- Trial name
- NCT06638372
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Hepatitis C
Study to Determine the Potential DDIs When the Daclatasvir/Asunaprevir/BMS-791325 Three Drug Antiviral Combination Tablet (FDC) is Coadministered With a Cocktail of Cytochrome P450 (CYP) Probe Substrates and Transporter Probe Substrates (Digoxin and Pravastatin) in Healthy Subjects
The primary purpose of this study is to assess the effect of the Daclatasvir/Asunaprevir/BMS-791325 fixed dose combination (FDC) tablet on the pharmacokinetics of the cocktail CYP and transporter probe substrates and to assess…
- Trial name
- NCT02045966
- Testing
- Cocktail, DCV 3DAA FDC, BMS-791325
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Hemodynamics, Caffeine
Improving Cognition With Neurodegradation Countermeasure
The goal of this randomized, placebo-controlled, three-condition, double-blind, within-participants crossover clinical trial is to compare caffeine, TeaCrine plus caffeine, and a placebo condition in ROTC or tactical personnel.
- Conditions
- Hemodynamics, Caffeine, TeaCrine, Cognitive Change
- Trial name
- NCT05715073
- Testing
- TeaCrine and Caffeine, Caffeine
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Healthy
Relative Bioavailability of Ibuprofen From a Single Fixed Dose Combination Tablet of Ibuprofen and Caffeine Compared to Single Tablets of Ibuprofen and Ibuprofen Lysinate
To investigate the relative bioavailability of ibuprofen from a (FDC) film-coated tablet of ibuprofen and caffeine vs. a tablet of ibuprofen (Brufen®) and a tablet of ibuprofen lysinate (Nurofen Immedia®).
- Trial name
- NCT01879371
- Testing
- Ibuprofen+caffeine FDC, Ibuprofen (Nurofen Immedia®), Ibuprofen (Brufen®)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Caffeine, Placebo
Caffeinated Chewing Gum on 400-meter Performance
20 trained sprinter were divided into caffeine Gum trial (CAF) and Placebo trial (PL) with a randomized, double-blind study design.
- Trial name
- NCT06430996
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Fatigue
Evaluate the Effectiveness and Safety of the Alpinia Galanga Formulation, Theacrine Formulation, and Caffeine Formulation on Fatigue, Mental Acuity, and Cognitive Health
The purpose of this study is to assess the effectiveness and safety of the Alpinia galanga formulation, Theacrine formulation, and Caffeine formulation on fatigue, mental acuity, and cognitive health among overall healthy…
- Trial name
- NCT05170113
- Testing
- Alpinia galanga formulation, Theacrine formulation, Caffeine formulation
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Neurologic Symptoms
Fasciculations in Healthy Adults After Consumption of Caffeine: an Ultrasound Study
Fasciculations are clinically defined as spontaneous intermittent contractions of a portion of muscles. Depending on associated symptoms they may be a sign of lower motor neuron disorder.
- Trial name
- NCT05977920
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zurich Regional Health Center
Cardiac Arrhythmia, Blood Pressure
The Effect of Energy Drink Ingredients on Cardiovascular Function in Men and Women 18-39 Years Old
1. Statement of the research question: Does the caffeine in energy drinks interact with other ingredients to affect cardiovascular function in healthy male and female adults after exercise? 2.
- Trial name
- EEDICF (NCT04149717)
- Testing
- Energy Drink Ingredients and Exercise
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Caffeine
Caffeine, Resistance Exercise and EMG
Introduction: Several studies have evaluated and confirmed the ergogenic effects of acute caffeine intake on sports performance.
- Trial name
- NCT06606652
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Athletic Performance
Effect of Caffeinated Chewing Gum on Vertical Jump Performance in Female Volleyball Players
This study aimed to examine the acute effects of caffeine intake through caffeinated chewing gum on the vertical jump performance of professional female volleyball players.
- Trial name
- CAF-GUM (NCT07240506)
- Testing
- Caffeinated chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Muttalip Ayar
Postdural Puncture Headache
Effect of Coffee on Postdural Puncture Headache After Cesarean Section
The purpose of this study is to investigate the effects of postoperative coffee consumption on postdural puncture headache (PDPH) and analgesic use in women undergoing cesarean section with spinal anesthesia.
- Trial name
- NCT07410741
- Testing
- Coffee Consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Volunteers
Open-label Study to Evaluate the Effects of NST-1024 on the PK of Multiple Drugs in Healthy Subjects
Phase 1, open label study to evaluate the effects of NST-1024 on the pharmacokinetics (PK) of caffeine (and paraxanthine), flurbiprofen, omeprazole, metoprolol, and midazolam (and 1-hydroxymidazolam) in healthy male and female…
- Trial name
- NCT05368831
- Testing
- NST-1024
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- NorthSea Therapeutics B.V.
Performance Enhancing Product Use
Effect of Creatine and Caffeine on Muscle Performance
To determine if creatine and caffeine can be co-supplemented without inhibiting the effects of creatine.
- Trial name
- NCT04290819
- Testing
- Creatine Monohydrate, Creatine Monohydrate and Caffeine, Caffeine
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Regina
Athletes
Effects of Caffeine on Elite Weightlifting Performance
Weightlifting is a high-intensity strength-power sport where performance depends on maximal force, power output, and technical execution in the snatch and clean and jerk.
- Trial name
- POWER-CAF (NCT07520864)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia Comillas
Focus: to Compare a Commercially Available Energy Drink, B Vitamins, Caffeine Alone, and Placebo for Effectiveness on Perceived Energy Level and Wakefulness
Efficacy of Energy Shots and Caffeine for Energy and Wakefulness Levels
The line of "5-hour Energy"® products are available over-the-counter as energy supplements. The appeal of these products involves ease of use, low caloric value, and the absence of sugar to prevent a "crash" later in the day.
- Trial name
- NCT01755299
- Testing
- Regular "5-hour Energy", Decaf "5-hour Energy", Compounded concentrated caffeine liquid
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- ProMedica Health System
Second Stage of Labor
Caffeine in the Second Stage of Labor in Low-risk Nulliparous Mothers at Term
Single blind, randomized control trial to determine benefit of caffeine and sodium benzoate on the second stage of labor
- Trial name
- NCT05906303
- Testing
- Caffeine and Sodium Benzoate Injection, Normal Saline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Reading Hospital and Medical Center
Fatigue
"WakeUp" for Vigilance Following Lunch
This is a single center, double-blind, placebo and active controlled clinical trial comprised of a single drink of WakeUp beverage (in 3 doses) compared to Caffeine (100mg) and placebo given to health volunteers.
- Trial name
- NCT04685005
- Testing
- "Wake Up", Caffeine
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Caffeine, Athletic Performance
The Effects of Caffeine on Physical Performance of Ice Hockey Players
To date, only one study has evaluated the effect of caffeine supplementation on athletic performance in ice hockey players finding a lack of ergogenic effect.
- Trial name
- cafhoc (NCT05170139)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Healthy
CYP1A2 and ADORA2A Genotypes and Endurance Performance.
The aim of this randomized, double-blind, placebo-controlled experiment will be to assess the potential effect of the selected gene polymorphism (CYP1A2, ADORA2A) on performance after caffeine ingestion.
- Trial name
- NCT06547307
- Testing
- Caffeine 2 mg, Caffeine 4 mg, Caffeine 0 mg
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Masaryk University