Clinical trials: Calcium Disorder
Insulin Resistance, Insulin Sensitivity
Calcium, Vitamin D and Metformin to Treat Insulin Resistance in Obese African American Adolescent Females
This is a feasibility study to examine the treatment with Metformin, vitamin D with calcium supplement for insulin resistance in obese, black, female teens.
- Conditions
- Insulin Resistance, Insulin Sensitivity, Obesity, Vitamin D Deficiency
- Trial name
- NCT01107808
- Testing
- Calcium and Vit D, Metformin, Vit D and Calcium
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Osteoporosis
PTH And Calcium Responses to Exercise (PACE) in Older Adults
Exercise that causes a decline in serum Calcium (Ca) as a result of dermal Ca loss stimulates bone resorption via an increase in Parathyroid Hormone (PTH).
- Trial name
- NCT02468817
- Testing
- Treadmill Exercise, Magnitude of Ca loss during Exercise at 26 degrees Celcius
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Osteoporosis
Soluble Corn Fiber and Calcium Utilization in Adolescents
The purpose of this study was to determine the effect of soluble corn fiber on calcium absorption and retention and gut microflora in adolescent boys and girls.
- Trial name
- NCT01571440
- Testing
- No soluble corn fiber, 12 g soluble corn fiber
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Purdue University
Diabetes Mellitus
Evaluating a Pharmacokinetic Drug Interaction Between Metformin Hydrochloride and Rosuvastatin Calcium
We investigate the potential pharmacokinetic drug-drug interaction between metformin extended release and rosuvastatin in healthy male volunteers who receive metformin extended release alone, rosuvastatin alone, and both together…
- Trial name
- NCT01775579
- Testing
- Glucophage SR tablet 750 mg, Crestor tablet 20 mg
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
Diagnostic Accuracy Of Seismocardiography for Coronary Artery Disease
This study aims to evaluate a new, non-invasive method for detecting coronary artery disease (CAD) using seismocardiography (SCG) and gyrocardiography (GCG).
- Trial name
- HF-CAD (NCT06880120)
- Testing
- Seismocardiography (SCG) and Gyrocardiography (GCG) Diagnostic Testing
- Where
- Uzbekistan
- Volunteers
- 1,534 people, healthy volunteers welcome
- Sponsor
- Heart Force Medical Inc.
Osteoporosis
Fructooligosaccharide and Calcium Absorption in Adolescent Girls
Fructooligosaccharides (FOS) are believed to have positive effects on calcium absorption and bone accrual during growth. This study aims to see whether the addition of fiber in the form of FOS to a calcium-containing beverage…
- Trial name
- NCT01005927
- Testing
- Fructooligosaccharide
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Purdue University
Dentin Hypersensitivity
A Comparison of Long-Term Effectiveness of Two Desensitizing Products
This randomized, controlled, clinical trial aimed to compare the 6- month clinical performance of a desensitizer that contains calcium phosphate TM with a two-step self-etch adhesive SE and placebo (distilled water).
- Trial name
- NCT03851900
- Testing
- Teethmate Desensitizer (TM), Clearfil SE Bond 2, Distilled water
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baskent University
Parathyroid Hormone, Tenofovir Disoproxil Fumarate
The Effects of Vitamin D and Calcium Supplementation to Parathyroid Hormone in CHB Patients Treated With TDF
Nucleot(s)ide is an antiviral drug that can reduce the number of viruses, reduce the risk of HCC, regress hepatic fibrosis and reduce death from Hepatitis B viral infection.
- Conditions
- Parathyroid Hormone, Tenofovir Disoproxil Fumarate, Chronic Hepatitis B Virus, Vitamin D
- Trial name
- TDF (NCT05313477)
- Testing
- Ergocalciferol Capsules, Calcium carbonate
- Where
- Thailand
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Dental Caries
2-year Caries Clinical Study: Arginine Fluoride-Free Toothpastes vs. NaF Toothpaste
The objective of this study is to evaluate the anticaries efficacy for three dentifrices (1.5% arginine in a calcium base, 8.0% arginine in a calcium base, and 0.32% sodium fluoride in a silica base) in a two-year caries clinical…
- Trial name
- NCT05560945
- Testing
- 0.32% Sodium Fluoride Dentifrice Toothpaste, 1.5% Arginine Dentifrice, 8.0% Arginine Dentifrice
- Where
- 3 sites in China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Healthy
Study Comparing Two Isoforms of Vitamin D Supplements for Infants
There are two different types of vitamin D - vitamin D3 (animal source) and vitamin D2 (plant source). Almost all the usual vitamin D preparations for infants available in Canadian pharmacies contain vitamin D3 which may not be…
- Trial name
- NCT01190137
- Testing
- Cholecalciferol (D3) or ergocalciferol (D2)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- McGill University
Cardiovascular Diseases, Heart Diseases
Aortic Calcium: Epidemiology and Progression -- Ancillary to MESA
To study the epidemiology of aortic calcium.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, Coronary Arteriosclerosis
- Trial name
- NCT00059124
- Volunteers
- 1,980 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Renal Insufficiency, Chronic, Renal Osteodystrophy
Kidney Yin/Yang Replenishment on Patients With Renal Osteodystrophy
Patients with serious chronic renal insufficiency usually develop secondary osteoporosis or bone loss, especially those with chronic dialysis, and the degree of bone loss is corrected with decrease of renal function.
- Trial name
- NCT01665651
- Testing
- Yougui granules, Zuogui granules
- Where
- 3 sites in China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bing Shu
Bone Atrophy, Alveolar, Bone Loss
Tunnel Access for Horizontal Alveolar Ridge Augmentation
Minimally invasive procedures with the tunnel technique have been suggested to decrease patient post-operative discomfort and morbidity in oral bone regeneration.
- Conditions
- Bone Atrophy, Alveolar, Bone Loss, Bone Resorption, Alveolar Bone Loss
- Trial name
- NCT06424223
- Testing
- Horizontal Ridge augmentation
- Where
- Italy
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Osteoporosis
Building Better Bones in Children
Calcium is important for healthy bone growth in children. Poor bone growth and development during childhood can lead to osteoporosis later in life.
- Trial name
- NCT00063037
- Testing
- Behavioral modification - nutrition education
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Spinal Cord Injury
Vitamin D and Calcium Study
Vitamin D aids in the body's ability to absorb calcium, it is a vital component in bone formation and break down. Reduced levels of vitamin D can indicate a vitamin deficiency and may depress serum calcium levels.
- Trial name
- NCT00857831
- Testing
- Vitamin D and Calcium
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hypophosphatemia, Familial, Rickets
Hypophosphatemic Rickets in Norway
The purpose of the study is to do a follow-up survey of all individuals with hereditary hypophosphatemia in Norway, focusing on manifestations in childhood and adolescence.
- Conditions
- Hypophosphatemia, Familial, Rickets, Hyperphosphatemia
- Trial name
- NCT01057186
- Testing
- Alfacalcidol; phosphate., Sevelamer
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Vitamin D Deficiency, Iodine Deficiency
Vitamin D, Iodine, and Lead Levels in Haitian Infants and Children.
Vitamin D deficiency is common worldwide, including in infants and children, and rickets remains a public health concern in many developing countries.
- Conditions
- Vitamin D Deficiency, Iodine Deficiency, Hypothyroidism, Rickets
- Trial name
- Haiti (NCT02301520)
- Where
- 2 sites in Haiti
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Asthma
Detection of Cav1 Calcium Channels in Inflammatory Cells of Asthmatic Children
Asthma affects about 10% of children and 6% of adults in industrialized countries. Lymphocytes (L) Th2, a T cell population (LT) producing interleukin (IL) -4, 5 and 13 are broadly involved in this pathology in experimental…
- Trial name
- CAVASTHME (NCT02809560)
- Testing
- Induced sputum method using hypertonic serum
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Micronutrient Deficiency
Assessing the Quality of Breast Milk
The purpose of the study is to establish a protocol for collecting representative samples of breastmilk (BM) that can be used to assess the effect of maternal micronutrient (MN) supplementation on milk MN concentrations.
- Trial name
- NCT02756026
- Testing
- Multiple micronutrient supplement (Nutri-Fem)
- Where
- Bangladesh
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Atherosclerosis
Effects of Omega-3 Fatty Acids and Menaquinone-7 on Thrombotic Tendency
Omega-3 fatty acids are notably present in fish oil and krill oil, and are known to have beneficial effects on the vasculature. Vitamin K2 is known for preventing vascular calcification.
- Trial name
- NCT00732576
- Testing
- menaquinone-7, fish oil, krill oil
- Where
- Netherlands
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center