Clinical trials: Calcium Hydroxide
Pulp Necroses
Revascularization of Immature Anterior Necrotic Teeth
The object of this study is to compare the effect of Calcium Hydroxide and Di-antibiotic paste as intracanal disinfectants in the 1st visit of revascularization of necrotic immature permanent anterior teeth.
- Trial name
- NCT03504332
- Testing
- intracanal disinfection in revascularization
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain, Healing
Effect of Using Nanochitosan Versus Calcium Hydroxide as Disinfectant on Pain and Apical Bone Healing
Effect of Using Nanochitosan versus Calcium Hydroxide as Intracanal Medications on the Postoperative Pain and Apical Bone Healing
- Trial name
- NCT03724266
- Testing
- Chitosan, Calcium Hydroxide
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bacterial Load Reduction, Postoperative Pain
Evaluation of Postoperative Pain and Bacterial Load After Hyalone or Calcium Hydroxide Medication in Mandibular First Molars
This randomized controlled clinical trial aims to evaluate the effect of Hyalone hydrogel compared with calcium hydroxide as an intracanal medicament on postoperative pain and bacterial load reduction in mandibular first molars…
- Trial name
- HYACAL-ENDO (NCT07775456)
- Testing
- Hyalone, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Periapical Periodontitis, Root Canal Infection
Antibacterial Efficacy of Bioceramic and Calcium Hydroxide Intracanal Medicaments
This study evaluates the antibacterial effectiveness of two different intracanal medicaments, Bio-C Temp and UltraCal XS , in mandibular molar teeth with chronic apical periodontitis.
- Conditions
- Periapical Periodontitis, Root Canal Infection, Intracanal Medicaments
- Trial name
- NCT07671326
- Testing
- Root canal treatment with Bio-C Temp, a calcium silicate-based bioceramic intracanal medicament, Root canal treatment with UltraCal XS, a calcium hydroxide-based intracanal medicament
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medipol University
Regenerative Endodontics
Regenerative Endodontics Using Different Intracanal Medicaments on Radiographic Outcomes and Periapical MMP-8 Levels
Two-session regenerative endodontic treatment was applied to 20 immature mandibular first molars with symptomatic irreversible pulpitis and symptomatic apical periodontitis.
- Trial name
- NCT05581706
- Testing
- Place the freshly prepared calcium hydroxide in to the root canals, Place the freshly prepared double antibiotic paste in to the root canals, Taking standart periapical radiography with film holder
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Ege University
Deep Caries
Calcium Silicate Versus Calcium Hydroxide in Two-step Indirect Pulp Treatment
Clinical and microbiological evaluation of Calcium silicate versus Calcium hydroxide in two-step indirect pulp treatment: Randomized clinical trial
- Trial name
- NCT03032978
- Testing
- Calcium hydroxide, Calcium silicate
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intervention
Effect of Boswellia Sacra as an Intracanal Medicament on Postoperative Pain Intensity and Bacterial Load Reduction
This research will study the effect of Boswellia Sacra versus calcium hydroxide as an intracanal medicament on postoperative pain intensity measured using numerical rating scale (NRS) and bacterial load reduction reduction…
- Trial name
- NCT05820646
- Testing
- Boswellia Sacra
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Indirect Pulp Cap
COMPARISON of MINERAL TRIOXIDE AGGREGATE and CALCIUM HYDROXIDE AS INDIRECT PULP CAPPING AGENTS in PRIMARY MOLARS
The study is designed as randomized clinical trial performed at the Department of Pediatric Dentistry , Pakistan Institute of Medical Sciences (PIMS) , Islamabad on primary molars requiring indirect pulp treatment in patients…
- Trial name
- NCT06807320
- Testing
- MTA pulp dressing material, Calcium Hydroxide (Ca(OH)2)
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Pain, Postoperative, Irreversible Pulpitis
Comparison of Nitrofurantoin and Calcium Hydroxide as Intracanal Medicaments in Alleviating Post-operative Pain
Intracanal medicaments have been frequently used in patients with endodontic and periradicular infection for the elimination of microorganisms.
- Trial name
- NCT04900571
- Testing
- Nitrofurantoin 100 MG
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Postoperative Pain, Pain, Dental
Influence of Intra Canal Medications on Postoperative Flare-up in Endodontic Re-treatment Cases
Is to evaluate the influence of the calcium hydroxide / chlorhexidine combination and calcium hydroxide alone as an intra-canal medication in postoperative flare-up in two visits endodontic retreatment cases
- Trial name
- NCT03064191
- Testing
- calcium hydroxide chlorhexidine combination, calcium hydroxide intra-canal medicament
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- rayan rabie dahab
Chronic Apical Periodontitis
Comparison of the Effects of N-acetylcysteine, Calcium Hydroxide, and Double Antibiotic Paste
This study aimed to evaluate the efficacy of N-acetylcysteine (NAC) used as an intracanal medicament on antibacterial activity, periapical RANKL/OPG ratio, and postoperative pain levels.
- Trial name
- NCT07340944
- Testing
- N Acetyl Cysteine, Calcium Hydroxide (Ca(OH)2), Double Antibiotic Paste
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Inflammation, Necrosis
Antimicrobial Pulpotomy of Primary Molars
There is a lack of evidence of the long-term successful outcomes of antimicrobial endodontic treatment for primary teeth. This study intended to evaluate (by survival analysis) the effectiveness of an antimicrobial pulpotomy…
- Trial name
- NCT01010451
- Testing
- Antimicrobial pulpotomy, Calcium hydroxide pulpectomy
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Apical Periodontitis, Periapical Radiolucency
Comparative Evaluation of Clinical and Radiographic Treatment Outcomes of Garlic Gel and Calcium Hydroxide as an Intracanal Medicament in Nonsurgical Root Canal Treatment of Permanent Teeth.
Researchers want to check how well garlic works inside permanent teeth as a medicament during root canal treatments. Garlic has shown to possess many helpful properties, like reducing inflammation, helping wounds heal, and…
- Trial name
- NCT07289971
- Testing
- Allium Sativum as an intracanal medicament
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Asymptomatic Apical Periodontitis
Antimicrobial Effect of Calcium Silicate and Pectin as Intracanal Medications in Necrotic Teeth With Periapical Lesions
It is tackling antimicrobial resistance in endodontics, specifically comparing different intracanal medications used in root canal treatment.
- Trial name
- NCT07423663
- Testing
- Calcium Hydroxide Intracanal medication, Calcium silicate based intracanal medication, Pectin
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Retreatment, Root Canal Retreatment
Comparison of the Efficacy of Calcium Hydroxide With Silver Nanoparticle and Conventional Calcium Hydroxide Intra Canal Medications on Post-Operative Pain in Symptomatic Root Canal Treatment Failure Cases:
The aim of this study is to measure and compare the effectiveness of nanosilver combined calcium hydroxide and conventional calcium hydroxide intracanal medications in reducing postoperative pain in patients with Symptomatic Root…
- Conditions
- Retreatment, Root Canal Retreatment, Nonsurgical Retreatment, Endodontic Failure
- Trial name
- CSNIMSRRT (NCT04213716)
- Testing
- silver nano particulate solution mixed with calcium hydroxide powder, conventional calcium hydroxide
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Apical Periodontitis
2% Chlorhexidine (CHX) vs CaOH2 (CH) Calcium Hydroxide Paste as an Intracanal Medicament
This is a Pilot Phase III single-blind randomized controlled clinical trial in patients, aged 18 years and older, presenting with symptoms of apical periodontitis.
- Trial name
- NCT03700788
- Testing
- Chlorhexidine, Calcium Hydroxide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Carious Primary Molars
Pulpotomy With CEM vs Pulpectomy With Ca(OH)2/Iodoform in Primary Molars
Will Calcium-Enriched Mixture (CEM) cement pulpotomy have less postoperative pain and more clinical and radiographic success compared to Calcium Hydroxide/Iodoform (Metapex) pulpectomy when managing second primary molars with…
- Trial name
- NCT07265063
- Testing
- Pulpotomy using Calcium-Enriched Mixture (CEM) Cement, Pulpectomy using Calcium Hydroxide/Iodoform Paste (Metapex)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp with Symptomatic Apical Periodontitis, Postoperative Dental Pain
Evaluation of Postoperative Pain and Antimicrobial Efficacy of Selenium Versus Calcium Hydroxide As Intracanal Medication in Mandibular First Molars with Necrotic Pulp and Symptomatic Apical Periodontitis
The main rational behind intracanal medicament is to kill the bacteria inside the root canal and to avert reinfection. In absence of nutrients, the bacteria remains after obturation in root canal may not survive.
- Conditions
- Necrotic Pulp with Symptomatic Apical Periodontitis, Postoperative Dental Pain, Antimicrobial Effect
- Trial name
- NCT06804330
- Testing
- root canal treatment and intracanal medicament
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Pulpitis - Irreversible, Pulp Necroses
Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars
The aim of this study was to compare the clinical and radiographic success of conventional root canal treatment and lesion sterilisation tissue repair methods in deciduous molars with necrotic or irreversible pulpitis.
- Conditions
- Pulpitis - Irreversible, Pulp Necroses, Root Canal Infection
- Trial name
- NCT06811636
- Testing
- Lesion sterilization and tissue repair, Conventional pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Post-Operative Pain, Chronic, Necrotic Pulp
Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp
Propolis is a resinous product of honeybees. Propolis is said to be effective against resistant microorganisms inside the root canal compared to the gold standard medication known as calcium hydroxide.
- Trial name
- NCT04983524
- Testing
- propolis, Calcium Hydroxide
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University