Clinical trials: Cancer
Gastrointestinal Disease, Colorectal Cancer
Randomized Controlled Study Comparing Colon Evaluation With The Pure-Vu System To A Standard Colonoscopy In Patients Who Are High Risk For Inadequate Bowel Preparation
The primary objective of this multi-center, prospective, randomized controlled trial is to evaluate the bowel cleansing after Pure-Vu use in outpatient subjects at high risk for inadequate colon preparation as compare to standard…
- Trial name
- RESCue (NCT04285008)
- Testing
- Pure-Vu System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Geriatric Care Survivorship Intervention for Improving the Overall Health of Older Adults With Stage I-III Breast Cancer Who Have Completed Curative Treatment
This trial studies the effect of a geriatric care survivorship intervention in improving the overall health of older adults who have completed curative treatment for stage I-III breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- NCT05928325
- Testing
- Comprehensive Geriatric Assessment, Health Education, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer (CRC)
Colon Cancer Liquid Biopsy Investigation of Methylation-based Biomarkers Evaluation Using Delta-HLD (CLIMBED)
CLIMBED (Colon cancer Liquid biopsy Investigation of Methylation-based Biomarkers Evaluation using Delta-HLD) is a non-randomized, observational, cross-sectional clinical validation study designed to assess the performance of…
- Trial name
- CLIMBED (NCT07168876)
- Where
- Argentina
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Epiliquid Holding, Inc
Cancer Pain
Opioid Titration in the Hospice Setting: Barriers Assessment and Modification of the Model Order Sheet and Protocol
The purpose of this study is to modify the opioid titration order sheet to meet the needs of the outpatient hospice population and to conduct a pilot trial to assess feasibility, utility, and derive preliminary efficacy data.
- Trial name
- NCT01230515
- Testing
- Individual patient interview, focus group and structured survey, interview, focus group and structured survey
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Lung Cancer
Duet TRS Used in Pulmonary Resections
The objectives of this clinical trial are to estimate the incidence and duration of air leaks and the incidence of prolonged air leaks (defined as > 5 days by the Society for Thoracic Surgery) when using the ENDO GIA Staplers…
- Trial name
- NCT01026025
- Testing
- Duet TRS
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Esophageal Neoplasms
Barrett's Esophagus and Esophageal Adenocarcinoma, Searching for Reliable Diagnostic RNA Plasma-based Biomarkers
This study is designed to perform a explorative search of the transcriptome to detect new circulating diagnostic sensitive and specific biomarkers in patients with Barrett's esophagus or esophageal adenocarcinoma.
- Trial name
- NCT05688176
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Asymptomatic
Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts
This randomized phase II trial studies how well abbreviated breast magnetic resonance imaging (MRI) and digital tomosynthesis mammography work in detecting cancer in women with dense breasts.
- Trial name
- NCT02933489
- Testing
- Contrast-enhanced Magnetic Resonance Imaging, Digital Tomosynthesis Mammography, Quality-of-Life Assessment
- Where
- 68 sites in United States, Germany
- Volunteers
- 1,516 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Breast Abnormality
Circulating Tumor Cells (CTCs): A Potential Screening Test for Clinically Undetectable Breast Carcinoma
With an estimated > 2 million women with undetected breast cancer in the United States, the need for improved early detection is imperative.
- Trial name
- NCT01322750
- Where
- United States
- Volunteers
- 3,125 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Polycystic Ovarian Syndrome
The Relationship Between Adipokines, Obesity and Insulin Resistance in Women With Polycystic Ovarian Syndrome
To evaluate possible clinical effects of adipokines , ( ghrelin, resistin and adiponectin), in obese and non-obese patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT02869750
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Breast Cancer, Transcriptomes
Transcriptomes Breast, Ovarian and Leukocyte Hereditary Genes Predisposing to Breast and / or Ovarian Cancer
This is a case-control study of molecular diagnostics. This study requires two steps: The first part of the study will be conducted on a population of 20 women without breast cancer and, or ovarian family (Healthy Volunteers…
- Conditions
- Breast Cancer, Transcriptomes, Molecular Diagnostic, Ovarian Cancer
- Trial name
- CASOHAR (NCT02560818)
- Testing
- collection of a blood sample and breast and ovarian tissue, use of a previous blood collection for patients
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
Glioblastoma
Expectations and Needs of a Glioblastoma Caregiver
Cancers of the central nervous system have a poor prognosis. Glioblastoma is most common glial tumor of the central nervous system.
- Trial name
- GLOIOS (NCT06490497)
- Testing
- Interview
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Hopital Nord Franche-Comte
Thyroid Cancer, Thyroid Nodule
Educational Videos for Thyroid Surgery Patient
The researchers aim to evaluate the performance of two groups of participants after receiving traditional education-one group supplemented with video-based education and the other without.
- Conditions
- Thyroid Cancer, Thyroid Nodule, TSH, Education of Patients
- Trial name
- NCT07823543
- Testing
- Thyroid Surgery Educational Video
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Cervical Cancer, Breast Cancer
Using Effective Provider-Patient Communication to Improve Cancer Screening Among Low Literacy Patients
What's the purpose of this study? This 4-year study is designed: (1) to teach primary care physicians how to recognize low health literacy patients and effectively counsel them on cancer screening using risk communication and…
- Conditions
- Cervical Cancer, Breast Cancer, Colorectal Cancer
- Trial name
- NCT01361035
- Testing
- Cancer risk communication skills training
- Where
- 5 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Medicine
Actinic Keratoses
PDT vs Peels for Treatment of Actinic Keratoses
The purpose of this study is to to compare photodynamic therapy (PDT) versus the combination of Jessner's solution and 35% trichloroacetic acid (TCA) chemical peels for the treatment of actinic keratoses on upper extremities.
- Trial name
- NCT04429308
- Testing
- Photodynamic Therapy, Chemical Peels
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Oral Cancer, Palliative Supportive Care
Early Palliative Care For Patients With Oral Cancer in Sri Lanka
The goal of this quasi experimental study is to develop and assess the effectiveness of an early palliative care intervention in patients with oral cancer in Sri Lanka.
- Conditions
- Oral Cancer, Palliative Supportive Care, Psychological Distress, Quality of Life of Patients
- Trial name
- NCT06726317
- Testing
- Early palliative care integration
- Where
- 4 sites in Sri Lanka
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Colombo
Breast Neoplasms
In Vitro Study of the Liquid Biopsy Test System of the Diagnostic Value, in Women With Various Forms of Breast Cancer
The Study Objective is to evaluate the diagnostic efficacy of the liquid biopsy system versus the gold standard mammography (or MRI, or Ultrasound) diagnosis in patients with suspected breast cancer.
- Trial name
- ARNABreast (NCT04890340)
- Testing
- ARNA Breast
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- ARNA Genomics US Inc.
Microbiota
Intestinal Microbiota and Thyroid Cancer
Thyroid cancer (TC), the most common malignancy of the endocrine system, is currently the fifth most common malignancy diagnosed in women (1).
- Trial name
- NCT03543891
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Melanoma
Tailored Intervention for Melanoma Patient's Families
The purpose of the investigators' study is to find the best way to provide information about sun protection and skin cancer detection.
- Trial name
- NCT00816374
- Testing
- Reading materials and discussions, Questionnaires
- Where
- 3 sites in United States
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Metabolic Syndrome
Metabolic Syndrome in Childhood Cancer Survivors
The research is devoted to studying the features of the metabolic syndrome in cancer survivors in childhood is supposed to answer the following questions: How can metabolic syndrome be diagnosed in the Russian population of…
- Trial name
- NCT03773718
- Where
- Russia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Breast Cancer
Effect of Midazolam Premedication Before Induction on the Functional Recovery After General Anesthesia in the Patients Undergoing Breast Surgery Due to Breast Cancer
Normally, higher levels of preoperational stress or anxiety affect behavior and recovery after the operation. Moreover, patients undergoing mastectomy are usually young women, and this demographic is known to experience higher…
- Trial name
- NCT01945476
- Testing
- midazolam premedication
- Where
- South Korea
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Yonsei University
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