Clinical trials: Cancer
Colorectal Cancer
The C-SPAN Coalition: Colorectal Cancer Screening and Patient Navigation
Participants will be mailed an invitation to complete CRC screening along with a fecal immunochemical test (FIT) kit, containing a 1-sample "Polymedco Over the Counter (OC) Sensor FIT", simplified English/Spanish instructions on…
- Trial name
- C-SPAN (NCT03181334)
- Testing
- Branch I, Branch II, Branch III
- Where
- 2 sites in United States
- Volunteers
- 7,711 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Caregiver, Malignant Neoplasm
Patient Portal and Navigation Program in Providing Information for Asian American Cancer Patients
This phase I/II trial studies how well patient portal and navigation program work in providing information for Asian American cancer patients.
- Conditions
- Caregiver, Malignant Neoplasm, Physician, Stage I Colorectal Cancer AJCC v8
- Trial name
- NCT03867916
- Testing
- Patient Navigation Program, Quality-of-Life Assessment, Survey Administration
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Barrett Esophagus
Impact of NBI on Patients Undergoing Endoscopic Eradication Therapy
This study tests the impact of narrow band imaging (NBI) on endoscopists' accurate detection of visible lesions and dysplasia in patients with Barrett's esophagus, as well as the effect of NBI on the choice of primary treatment…
- Trial name
- NCT03191604
- Testing
- Video intervention
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Eczema/Atopic Dermatitis, Cancer
Patient Forward Access to Clinical and Technological Research: Genetic Influences on Cancer and Atopic Dermatitis
This Patient Forward study intends to conduct research to investigate potential genetic factors causing cancer and eczema/atopic dermatitis.
- Trial name
- PFACTR02 (NCT04362852)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Cancer Screening, Early Detection of Cancer
Risk Reduction Program for Women Having High Risk of Breast Cancer
An intervention program involving education, guidance, counseling, case management and surveillance based on the Health Belief Model will be implemented on women with high risk of breast cancer.
- Conditions
- Cancer Screening, Early Detection of Cancer, Breast Cancer, Preventive Health Care
- Trial name
- BrCaRRP (NCT04304404)
- Testing
- Breast Cancer Risk Reduction Program (BrCaRRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Skin Cancer
In Vivo Confocal Microscopy of Cutaneous Neoplasms and Normal Skin
The purpose of this study is to investigate new non-invasive imaging techniques for the evaluation of skin lesions, as well as normal skin.
- Trial name
- NCT00588315
- Where
- 4 sites in United States
- Volunteers
- 1,889 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
the Beijing Randomized Study Of Prostate Cancer Screening
BROPCS is a randomized trial study comparing the effectiveness of traditional systematic biopsies and bpMRI followed targeted biopsies with PSA > 4ng/ml in initial screening.
- Trial name
- BROPCS (NCT05961514)
- Testing
- Target biopsies, systemic biopsies
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Chronic Obstructive Pulmonary Disease (COPD)
Temple Health Chest Initiative (THCI 2.0)
Chronic obstructive pulmonary disease is highly prevalent globally, with considerable morbidity and mortality associated. In the US, it is the 4th leading cause of death, as well as contributing to significant costs on healthcare…
- Trial name
- NCT06933758
- Testing
- Determine COPD prevalence utilizing spirometry along with CT scans and symptom assessments in the THCI lung cancer screening populatio
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Temple University
Gut Microbiota
Establishment of Individualized Immunotherapy Strategy and Platform Based on Changes of Intestinal Microbiota
To explore and analyze the relationship between intestinal flora changes and the efficacy of individualized immunotherapy in patients with upper gastrointestinal cancer, and to find new biomarkers to predict the efficacy of…
- Trial name
- NCT05065515
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Ovarian Carcinoma
Prophylactic Salpingectomy With Delayed Oophorectomy
The goal of this clinical research study is to compare ovarian cancer screening, risk-reducing salpingo-oophorectomy (RRSO), and prophylactic salpingectomy with delayed oophorectomy (PSDO).
- Trial name
- NCT01907789
- Testing
- Ovarian Cancer Screening, Prophylactic Salpingectomy with Delayed Oophorectomy, Risk-Reducing Salpingo-Oophorectomy
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Healthy Volunteers Bioequivalence or Bioavailability Study
A Study to Assess the Relative Bioavailability of Process Variants of Selumetinib in Healthy Male Volunteers
A Study to assess, against a reference selumetinib capsule, if the drug levels of a variant of selumetinib capsule are comparable, and to assess how drug levels differed in another variant of Selumetinib in Healthy Male…
- Trial name
- NCT02322749
- Testing
- selumetinib 75mg single dose
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Bladder Cancer
Tumorspecific T-cell Immunity in Bladder Cancer as Prognostic Marker
Bladder cancer is generally susceptible to immunotherapeutic measures. The investigators will characterize 40 patients with muscle-invasive bladder cancer regarding the existence and frequency of tumorspecific T-cells and…
- Trial name
- NCT01198808
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Caregiver Burden, Caregiver Burnout
A Study of Meaning-Centered Psychotherapy for Caregivers to People With Cancer
Participants will complete 1 set of questionnaires about 2 weeks before beginning their Meaning-Centered Psychotherapy for Caregivers/MCP-C or standard Supportive Psychotherapy for Caregivers/SP-C sessions.
- Conditions
- Caregiver Burden, Caregiver Burnout, Caregiver Stress Syndrome
- Trial name
- NCT06307535
- Testing
- Meaning-Centered Psychotherapy for Caregivers, Supportive Psychotherapy for Caregivers
- Where
- 8 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pancreas Cancer, Pancreatic Ductal Adenocarcinoma
Clinical Performance of Medical Device Software "Lipidica 1.0" for Processing Data Generated by Lipidomic Analysis in Pancreatic Cancer Screening
Software "Lipidica" is intended to be used for processing data generated by the in-house in vitro diagnostic medical device for lipidomic testing for the purpose of screening Pancreatic cancer (PaC) in the population at high risk…
- Conditions
- Pancreas Cancer, Pancreatic Ductal Adenocarcinoma, Hereditary Diseases, Pancreatitis, Chronic
- Trial name
- NCT06549725
- Testing
- software Lipidica, endoscopic ultrasonography, magnetic resonance
- Where
- 16 sites in Czechia
- Volunteers
- 419 people, healthy volunteers welcome
- Sponsor
- Lipidica, a.s.
Motivational Intervention, Cancer
Hope-Focused Motivational Interviewing in Cancer Patients
This study aims to examine the effects of hope-focused motivational interviewing on levels of hope, self-efficacy, and self-compassion in patients with cancer receiving radiotherapy, using a randomized controlled design.
- Conditions
- Motivational Intervention, Cancer, Hope, Self-Compassion
- Trial name
- NCT07585838
- Testing
- Hope-Focused Motivational Interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Nasopharyngeal Carcinoma
KSD-101 Therapy for Standard Treatment Failed EBV-associated NPC: an Exploratory Clinical Trial
The main purpse of this study is to evaluate the safety of KSD-101 in patients with EBV-associated Nasopharyngeal Carcinoma,to evaluate the initial clinical outcomes and evaluate the immune response to KSD-101 for the treatment…
- Trial name
- NCT06370026
- Testing
- KSD-101
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Posterior Fossa Hemorrhage, Lung Cancer
Pilot Study of Model Based Iterative Reconstruction Using 64-Slice
This study is being performed to confirm that the new technique, Model-Based Iterative Reconstruction (MBIR) with reduced radiation dose can deliver equivalent image quality for CT scans compared to current techniques (Filtered…
- Conditions
- Posterior Fossa Hemorrhage, Lung Cancer, Flank Pain, Urolithiasis
- Trial name
- MBIR (NCT01431378)
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Solid Tumors
A Study to Investigate the Effect of Single Dose of AZD6094 (600 mg) on Cardiac Repolarization in Healthy Volunteers
This is a randomized, placebo-controlled, double-blind, 3-way crossover phase I study being conducted on healthy volunteers to investigate the effect of single dose of AZD6094 (600 mg) on cardiac repolarization under…
- Trial name
- NCT03258515
- Testing
- AZD6094 200 mg, Moxifloxacin
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Infantile Hemangiomas
Ontogeny of Infantile Hemangiomas With Skin Imaging Modalities
A combined set of quantitative skin imaging methods will quantitatively describe the natural ontogeny and the response to standard treatments over time in patients with infantile hemangiomas.
- Trial name
- NCT02061735
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Metabolic Disturbance
Remote Time-restricted EAting DeliverY
This study will evaluate the implementation and effectiveness of free-living TRE on biological and behavioural breast cancer risk factors.
- Trial name
- READY (NCT05454943)
- Testing
- Standardized TRE Protocol, Personalized TRE Protocol, External Support for TRE
- Where
- Canada
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of Toronto
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