Clinical trials: Cancer Cachexia
Cachexia, Lymphoma
Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer
RATIONALE: Celecoxib may help relieve moderate or severe pain associated with cancer. It may also decrease weight loss and improve muscle strength in cancer patients.
- Conditions
- Cachexia, Lymphoma, Melanoma (Skin), Ovarian Cancer
- Trial name
- NCT00093678
- Testing
- celecoxib, anticachectic therapy, nutritional support
- Sponsor
- Eastern Cooperative Oncology Group
Gastrointestinal Neoplasms, Bronchial Carcinoma
Effect of an Antioxidant on Cancer-Cachectic Patients Undergoing Exercise Training
The purpose of the study is to tests the hypothesis, that N-acetylcysteine (a thiol-antioxidant)improves the exercise training effect on cancer patients that experience weight loss (cachexia) as assessed by muscle mass and…
- Conditions
- Gastrointestinal Neoplasms, Bronchial Carcinoma, Hodgkin Disease, Non-Hodgkin Lymphoma
- Trial name
- NCT00196885
- Testing
- N-acetylcysteine
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- German Cancer Research Center
Stage IV Non-small Cell Lung Cancer, Cachexia
Ruxolitinib for Cancer Cachexia
To assess toxicity with use of Ruxolitinib in NSCLC cachexia patients; to associate levels of JAK/STAT signaling in blood, adipose, and muscle pre- and post-ruxolitinib treatment with changes in cachexia and anorexia.
- Trial name
- NCT04906746
- Testing
- Identify any dose-limiting toxicity (DLT) when ruxolitinib is administered to NSCLC cachexia patients.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tu Dan
Cachexia, Pancreatic Neoplasms
A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Pancreatic Cancer Related Cachexia
The purpose of this study is to evaluate the effectiveness and safety of infliximab, the active ingredient in Remicade, for the treatment of cachexia in pancreatic cancer patients who are receiving chemotherapy with gemcitabine.
- Trial name
- NCT00060502
- Testing
- Infliximab; Gemcitabine
- Volunteers
- 73 people
- Sponsor
- Centocor, Inc.
Hematologic Diseases, Cachexia; Cancer
WB-EMS and Nutrition in Patients With Hematological Malignancies
This study evaluates the effects of a whole-body electromyostimulation (WB-EMS) training combined with individualized nutritional support on skeletal muscle mass, body composition, muscle strength/function, quality of life…
- Conditions
- Hematologic Diseases, Cachexia; Cancer, Leukemia, Myeloma
- Trial name
- NCT03556748
- Testing
- whole-body electromyostimulation
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Cancer, Cachexia; Cancer
Improvement of Neuromuscular Function, Fatigue and Quality of Life by Optimizing Muscle Building and Nutrition in Colorectal Cancer: a Pilot Study
This study is based on the assumption that muscle strength and muscle mass will be better preserved in an "intervention" group with specific management combining retraining and nutritional monitoring compared to the "no…
- Trial name
- ColCanter (NCT04136249)
- Testing
- Over physical activity
- Where
- France
- Volunteers
- 30 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Cachexia; Cancer; Sarcopenia
Telemedicine Nutritional Counseling for Cancer Cachexia in Pakistan
What is this study about? Cancer often causes unwanted weight loss and loss of appetite, a condition called "cancer cachexia." This affects patients' strength, quality of life, and ability to tolerate cancer treatment.
- Trial name
- TELE-CACHE (NCT07606417)
- Testing
- Telemedicine-Delivered Nutritional Counseling, Standard In-Person Nutritional Counseling
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- King Edward Medical University
Pancreatic Cancer, Cancer Cachexia
Florida Pancreas Collaborative Next Generation Biobank
The goal of this study is to partner with individuals known or suspected to have pancreatic cancer to build a biobank dedicated to minimizing disparities and personalizing care for individuals affected by pancreatic cancer.
- Trial name
- NCT03851133
- Testing
- Blood Sample Collection, Tumor Sample collection, Data Collection
- Where
- 14 sites in United States
- Volunteers
- 500 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Cancer Cachexia (CC), Cancer Patients With Solid Tumors
Efficacy and Safety of MitoQ in Improving Cancer Cachexia
Muscle strength was evaluated in subjects with malignant solid tumors and cachexia after 12 weeks of oral MitoQ treatment.
- Trial name
- NCT07836777
- Testing
- MitoQ (mitoquinol mesylate)
- Volunteers
- 20 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Cancer Cachexia, Pancreatic Cancer
Parenteral Nutrition Support for Patients With Pancreatic Cancer
The purpose of this study is to determine whether the additional nutrition support is improving the nutritional status of patients suffering cancer caxechia or not.
- Trial name
- NCT00919659
- Testing
- parenteral nutrition
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- CONKO-Studiengruppe
Cancer Cachexia
A Multicenter Real World Study of Kanglaite for Cancer Cachexia
A prospective, multi-center real-world study of the effectiveness and safety of Kanglaita Injection/Capsule in Chinese patients with cancer cachexia
- Trial name
- NCT03631459
- Testing
- Kanglaite Injection/Capsules
- Where
- 2 sites in China
- Volunteers
- 100,000 people
- Sponsor
- Zhejiang Kanglaite Pharmaceutical Co.Ltd
Resectable Pancreatic Adenocarcinoma
Identify microRNAs in Cachexia in Pancreatic Carcinoma
The purpose of this study is to determine the proportion of pancreatic patients who experience weight loss and cachexia, and to identify any differences in the genes between patient groups.
- Trial name
- SCC-miRPanCa (NCT05275075)
- Testing
- Pancreatic cancer microRNA and messenger RNA expression.
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Oklahoma
Cancer Cachexia, Head and Neck Cancer
The Effect of Curcumin for Treatment of Cancer Anorexia-Cachexia Syndrome in Patients With Stage III-IV of Head and Neck Cancer
A study of Curcumin to prevent cancer anorexia and cachexia Syndrom in locally advance and advance stage head and neck cancer (stage III, IV)
- Conditions
- Cancer Cachexia, Head and Neck Cancer, Head and Neck Neoplasms
- Trial name
- CurChexia (NCT04208334)
- Testing
- Curcumin
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
SCLC, Extensive Stage
Nanocrystalline Megestrol + Immunochemo As 1st-Line for ES-SCLC Cachexia
This study hypothesizes that nanocrystalline megestrol acetate can improve the cachexia condition in patients and enhance the efficacy of immunochemotherapy regimens.
- Trial name
- NCT06793228
- Testing
- Nanocrystalline Megestrol Acetate, Tislelizumab, PTOC
- Where
- 4 sites in China
- Volunteers
- 250 people
- Sponsor
- Henan Cancer Hospital
Advanced Cancer, Weight Loss
Olanzapine in Patients With Advanced Cancer and Weight Loss
The goal of this clinical research study is to find the highest tolerable dose of the drug Olanzapine that can be given to patients with advanced cancer who are experiencing weight loss.
- Trial name
- NCT00489593
- Testing
- Olanzapine
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- M.D. Anderson Cancer Center
Anorexia
Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients.
This study was 8 weeks randomized, double-blind trail to assess the effect of mirtazapine versus megestrol acetate in treatment of anorexia-cachexia in advanced cancer patients in 80 patients.
- Trial name
- NCT05380479
- Testing
- Mirtazapine, Megestrol Acetate
- Where
- Bangladesh
- Volunteers
- 80 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Cancer
Effect of Nutritional Formula (Protison) on Various Cancer Patients: A Randomized Clinical Trial
Many studies (including ASPEN/ESPEN) have demonstrated that balanced diet formula rich in omega 3 fatty acids (ω-3 FA), fibers, protein as well as mineral, vitamins (trace elements) are essential for cancer patients to improve…
- Trial name
- Protison (NCT04643613)
- Testing
- Protison cancer nutritional formula (PCNF)
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- Chung Shan Medical University
Cachexia
Retrospective Review of Cachexia in Lung and Gastrointestinal Cancer Patients
The objective is to perform a retrospective chart review of patients with cachexia related to cancer in patients treated at UT Southwestern Medical Center and Parkland Hospital to evaluate the prognosis and practice patterns in…
- Trial name
- NCT03606317
- Volunteers
- 20,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Pancreatic Cancer
The Significance of Postoperative Muscle Wasting in Pancreatic Cancer
To assess the impact of preoperative sarcopenia and postoperative skeletal muscle wasting on the outcomes of patients with resectable pancreatic cancer who underwent pancreatectomy.
- Trial name
- NCT06093009
- Testing
- pancreatectomy
- Where
- Taiwan
- Volunteers
- 208 people
- Sponsor
- National Cheng-Kung University Hospital
Hepatocellular Carcinoma
Effects of EPA Supplementation on Patients With Unresectable Hepatocellular Carcinoma.
Dietary intervention with eicosapentaenoic acid combined with chemotherapy may shift inflammatory mediators toward resolution in non-resectable hepatocarcinoma and help to preserve muscle mass.
- Trial name
- NCT07664007
- Testing
- Eicosapentaenoic acid oral lipidic emulsion, Pacebo oral lipidic emulsion
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón