Clinical trials: Cancer Childhood
Childhood Cancer, ALL, Childhood
Retun-to-school Adaptation Program for Children With Cancer
The aim of this action research is to: Stage 1: Conduct an in-depth investigation into the adaptation challenges faced by children aged 8-17 who are being treated for cancer during their return to school, from both the children's…
- Conditions
- Childhood Cancer, ALL, Childhood, AML, Childhood, Lymphoma
- Trial name
- web-based (NCT06389357)
- Testing
- training and counselling, Interview
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gazi University
Late Effect, Childhood Cancer
The Swiss Childhood Cancer Survivor Study - Follow-up (SCCSS-FollowUp)
The SCCSS-FollowUp is a national, multicenter cohort study designed to investigate late effects in childhood cancer survivors in a prospective and longitudinal way.
- Trial name
- SCCSS-FU (NCT04732273)
- Testing
- Physical examination, diagnostic tests, laboratory tests, Personal history, questionnaire
- Where
- 3 sites in Switzerland
- Volunteers
- 3,000 people
- Sponsor
- University of Bern
Cancer, Parent
Adapting The Fear Of Recurrence Therapy (FORT) for Parents and Establishing Acceptability and Feasibility
Clinical levels of fear of cancer recurrence (FCR) affect up to 59% of adult cancer survivors. Family caregivers experience equal or greater levels of FCR, which has been linked to lower quality of life and increased distress.
- Conditions
- Cancer, Parent, Fear of Cancer Recurrence, CBT
- Trial name
- Parent-FORT (NCT06872840)
- Testing
- Parent Fear of Recurrence Therapy (Parent-FORT)
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Ottawa
Childhood Malignant Tumors of Lower Limbs
Diaphyseal Reconstruction of Malignant Tumors in Children
Primary malignant bone tumors represent 5% of malignant tumors in children, 90% of which are osteosarcomas or Ewing sarcomas. The objective of oncological resection is local control of the disease.
- Trial name
- RDTM (NCT06361290)
- Testing
- Data collection from hospital medical records
- Where
- 2 sites in France
- Volunteers
- 91 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Childhood Non-Hodgkin Lymphoma, Childhood Acute Lymphoblastic Leukemia
Goal Management Training for Adult Survivors of Childhood Leukemia and Non-Hodgkins Lymphoma With Neurocognitive Sequelae
Survivors of childhood cancer are at risk for developing neurocognitive sequelae. Multiple meta-analyses demonstrate significant deficits in overall intellectual abilities, academic functioning and specific cognitive skills among…
- Conditions
- Childhood Non-Hodgkin Lymphoma, Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia
- Trial name
- NCT04541056
- Testing
- Goal Management Training (GMT), Brain Health Workshop (BHW)
- Where
- 3 sites in Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Childhood Cancer, Cancer-related Problem/Condition
Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
When it comes to exercise and sport for children and adolescents with cancer, there is often still the opinion that physical activity has a negative effect on the weakened body suffering from cancer.
- Conditions
- Childhood Cancer, Cancer-related Problem/Condition, Cognitive Side Effects of Cancer Therapy, Physical Activity
- Trial name
- KiKli Fit (NCT06839794)
- Testing
- Cognitively challenging physical activity for paediatric cancer patients, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
Testis Cancer, Germ Cell Tumor
Role of Axumin PET Scan in Germ Cell Tumor
Investigators will use Axumin PET/CT to help with the imaging modalities to determine the presence of occult retroperitoneal disease.
- Conditions
- Testis Cancer, Germ Cell Tumor, Testicular Cancer, Germ Cell Tumor of Testis
- Trial name
- TESTPET (NCT03426865)
- Testing
- Axumin PET scan
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Texas Southwestern Medical Center
Adult Solid Neoplasm, Childhood Solid Neoplasm
Gene-Modified T Cells, Vaccine Therapy, and Nivolumab in Treating Patients With Stage IV or Locally Advanced Solid Tumors Expressing NY-ESO-1
This phase I trial studies the side effects and the best dose of nivolumab when given together with gene-modified T cells and vaccine therapy in treating patients with solid tumors that express the cancer-testes antigen NY-ESO-1…
- Conditions
- Adult Solid Neoplasm, Childhood Solid Neoplasm, Metastatic Neoplasm
- Trial name
- NYM (NCT02775292)
- Testing
- Aldesleukin, Cyclophosphamide, Fludarabine Phosphate
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Adverse Childhood Experiences, Cancer, Breast
Adverse Childhood Experiences, Adaptation and Breast Cancer
Adverse Childhood Experiences (ACEs) have long been linked to mental health problems in adulthood. In the case of cancer, no study has considered that such an anteriority could make patients more vulnerable emotionally, even…
- Conditions
- Adverse Childhood Experiences, Cancer, Breast, Attachment Styles, Resilience, Psychological
- Trial name
- CAPONE (NCT05843539)
- Testing
- Biological and epigenetic measures
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University of Lorraine
Childhood Cancer, Fertility Issues
Addressing Fertility Information Needs and Distress
The purpose of this study is to develop and refine a behavioral intervention to address fertility-related information needs and fertility-related distress among female adult survivors of childhood cancer.
- Trial name
- NCT06834945
- Testing
- AYA SPARK
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Acute Lymphoblastic Leukemia ALL, Childhood Cancer Survivors
Online Physical Activity and Health Counseling for Survivors of Childhood Acute Lymphoblastic Leukemia
Advances in the medical treatment of childhood acute lymphoblastic leukemia (ALL) have resulted in 5-year survival rates above 90%- however, the success is not without consequences.
- Conditions
- Acute Lymphoblastic Leukemia ALL, Childhood Cancer Survivors, Exercise, Rehabilitation Exercise
- Trial name
- OPAC-ALL (NCT07042932)
- Testing
- Exercise
- Volunteers
- 82 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Solid Tumor, Adult, Solid Tumor, Childhood
An Exploratory Study to Evaluate Immune Determinants of the Response to Adoptive Cell Therapy (ACT) in Solid and Hematologic Tumors
This is a study to explore the phenotypic and transcriptional changes of different cellular components in the tumor following the injection of somatic cell therapy drugs.
- Conditions
- Solid Tumor, Adult, Solid Tumor, Childhood, Hematologic Cancer
- Trial name
- PIONEER (NCT05481502)
- Testing
- Tumor biopsy, Blood sample, Bone marrow sample
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Solid Tumor, Solid Tumor, Childhood
A Study of Romiplostim to Prevent Low Platelet Counts in Children and Young Adults Receiving Chemotherapy for Solid Tumors
The purpose of this study is to find out whether romiplostim can help prevent low platelet counts caused by N8 or EFT chemotherapy, reduce the number of platelet transfusions required during chemotherapy, and prevent treatment…
- Conditions
- Solid Tumor, Solid Tumor, Childhood, Solid Carcinoma
- Trial name
- NCT04671901
- Testing
- Romiplostim
- Where
- 7 sites in United States
- Volunteers
- 2 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Minimal Residual Disease, Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes
Daratumumab and Donor Lymphocyte Infusion in Treating Participants With Relapsed Acute Myeloid Leukemia After Stem Cell Transplant
This phase I/II trial studies the side effects and best dose of donor lymphocyte infusions when given together with daratumumab and to see how well they work in treating participants with acute myeloid leukemia that has come back…
- Conditions
- Minimal Residual Disease, Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia
- Trial name
- NCT03537599
- Testing
- Daratumumab, Donor Lymphocyte Infusion, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Sumithira Vasu
Solid Tumor, Adult, Solid Tumor, Childhood
Evaluation of the Impact of Chemotherapy on Body Odor in Adolescents and Young Adults in Oncology
The appearance of unpleasant body odors in adolescent Young adult (aya) wille be evaluated undergoing chemotherapy
- Conditions
- Solid Tumor, Adult, Solid Tumor, Childhood, Chemotherapy Effect
- Trial name
- ODORAJA (NCT04899505)
- Testing
- Evaluation on appearance of unpleasant body odors
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Institut Curie
Childhood Cancer Survivors
Exercise and Pain in CCS
The purpose of this study is to demonstrate that integration of exercise intervention into standard post-cancer directed treatment care will improve patient reported pain, decrease the need for medications to manage chronic pain…
- Trial name
- NCT05562193
- Testing
- Physical activity intervention coupled with standard post-cancer directed treatment care, Standard post-cancer directed treatment care control
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Childhood Renal Tumor
Clinical Trial for Patients With a Stage IV Childhood Renal Tumor, Comparing Upfront Vincristine, Actinomycin-D and Doxorubicin (Standard Arm) With Upfront Vincristine, Carboplatin and Etoposide (Experimental Arm)
Nephroblastoma (Wilms tumor, WT) is the most common renal tumor of childhood representing ± 6% of all childhood malignancies. The diagnosis is established on clinical and radiological grounds.
- Trial name
- RANDOMET (NCT03669783)
- Testing
- treatment Vincristin, treatment Actinomycin-D, treatment Doxorubicin
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Late-effects of Childhood Cancer
SURfit - A Physical Activity Intervention for Childhood Cancer Survivors
Exercise can play a major role to mitigate or even prevent late effects in cancer survivors, such as cardiovascular disease, obesity, osteoporosis, fatigue, depression, reduced quality of life, mental health and physical…
- Trial name
- SURfit (NCT02730767)
- Testing
- partially supervised exercise intervention
- Where
- Switzerland
- Volunteers
- 151 people
- Sponsor
- University of Zurich
Solid Tumor, Adult Central Nervous System Germ Cell Tumor
Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor
RATIONALE: Giving high-dose chemotherapy before an autologous stem cell transplant stops the growth of tumor cells by stopping them from dividing or killing them.
- Conditions
- Solid Tumor, Adult Central Nervous System Germ Cell Tumor, Adult Rhabdomyosarcoma, Childhood Central Nervous System Germ Cell Tumor
- Trial name
- NCT00638898
- Testing
- busulfan, melphalan, topotecan hydrochloride
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- City of Hope Medical Center
Predisposition, Genetic, Cancer Childhood
EXOme Rare Cancers in Children (EXOCARE)
Other than high-dose radiation and previous chemotherapy, few strong risk factors have been identified as causes of childhood cancer.
- Conditions
- Predisposition, Genetic, Cancer Childhood, Development Delay
- Trial name
- EXOCARE (NCT03472807)
- Testing
- Collection of blood sample or saliva, Collection of a tumor sample taken before the participation of the patient in study, Collection of blood sample if tumor sample is not available
- Where
- 27 sites in France, Reunion
- Volunteers
- 169 people
- Sponsor
- University Hospital, Angers