Clinical trials: Cancer Colon
Colon Cancer
Narrow-Band Imaging Versus Standard White Light for the Detection of Serrated Lesions in the Proximal Colon
This is a study to determine if using Narrow-Band Imaging of the colon, rather than the usual white light on the colon, will improve the detection of a type of polyp called serrated.
- Trial name
- NCT01572428
- Testing
- Inspection with Narrow-Band Imaging(NBI), Standard White Light
- Where
- United States
- Volunteers
- 898 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Polyp, Colorectal Adenoma
Standard Colonoscopy Versus Colonoscopy With Endocuff Vision
This study seeks to compare colonoscopy results between a standard method and one using a distal scope attachment (Endocuff Vision).
- Conditions
- Colorectal Polyp, Colorectal Adenoma, Colon Cancer
- Trial name
- NCT03361917
- Testing
- Endocuff Vision
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Breast Cancer, Cervical Cancer
Improving Compliance With Medical Testing Guidelines
The study hypothesis is that clearer visual presentation of guideline recommendations and educational outreach, or academic detailing, can improve guideline compliance.
- Conditions
- Breast Cancer, Cervical Cancer, Prostate Cancer, Colon Cancer
- Trial name
- NCT02430948
- Testing
- Color-coded materials, Academic detailing, Standard support
- Where
- 2 sites in United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Beth Israel Medical Center
Colon Cancer
Novel Biophotonics Methodology for Colon Cancer Screening
This is a proposal to establish a Bioengineering Research Partnership (BRP). The major objective of the BRP is to refine and provide comprehensive, definitive multi-center validation of these novel methodologies for colorectal…
- Trial name
- BRP (NCT04031963)
- Where
- United States
- Volunteers
- 857 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Bowel Cancer, Colon Cancer
Serial SMS Reminders and an Opt-out Mailed FIT Kits to Improve Colorectal Screening Participation: A Single Center RCT
This pilot study is a 2-armed randomized controlled trial assessing the impact of a multimodal approach on colorectal cancer screening participation rates in a Federally Qualified Health Center.
- Trial name
- NCT03479645
- Testing
- Serial text messages and mailed FIT kit
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Colon Cancer
Impact of a Mailed Educational Reminder on Fecal Occult Blood Testing (FOBT): A Randomized Controlled Trial
The purpose of our randomized controlled trial is to determine whether mailed educational reminders would increase fecal occult blood test (FOBT) card return rates and, therefore, improve patient compliance with colonrectal…
- Trial name
- NCT00534053
- Testing
- Mailed Educational Reminder
- Where
- United States
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Colon Disease, Colonic Neoplasms
3-day vs. 1-day Low Residue Diet Influence in Colonoscopy Preparation and Patient Tolerability
Colonoscopy is one of the most common methods for the diagnosis and treatment of lower gastrointestinal tract diseases and provides a unique opportunity to identify early neoplastic lesions.
- Trial name
- NCT02955901
- Testing
- 3 day low residue diet prior to the colonoscopy, 1 day low residue diet prior to the colonoscopy
- Where
- Portugal
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Colonic Polyp, Colonic Diseases
Optical Polyp Testing for In Vivo Classification
Small growths detected in the colon (polyps) during a colonoscopy may or may not have the potential to develop into cancer. However, since visual inspection alone cannot separate all potentially harmful polyps from harmless ones…
- Conditions
- Colonic Polyp, Colonic Diseases, Colonic Neoplasms, Colonic Adenoma
- Trial name
- OPTIC (NCT03139942)
- Testing
- Optical spectral reflectance and autofluorescence imaging
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Colon Polyp, Adenoma Colon
AmplifEYE Colonoscopy vs Standard Colonoscopy
Colonoscopy screening is proven to reduce mortality rates for colorectal cancer, which relies on early detection and removal of colonic polyps.
- Conditions
- Colon Polyp, Adenoma Colon, Serrated Polyp, Colonic Neoplasms
- Trial name
- NCT03814369
- Testing
- AmplifEYE
- Where
- Hong Kong
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Colon Cancer
The Comparison of Postoperative Pain After Colon Resection in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With 'PAINSTOP' Equipment
Colon resection is one of the major surgery, the postoperative pain is so severe that it is necessary to use additional analgesics as well as a patient controlled analgesia (PCA).
- Trial name
- NCT03011359
- Testing
- Optimizing B.I (New) PCA mode, Conventional PCA mode
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Breast Cancer, Lung Cancer
Effects of Somnage® in the Management on Sleep and Mood in Cancer Patients
The aim of this placebo-controlled randomized study is to evaluate the effects of Melatonin 1mg/Zn 30% VNR/Mg 100% VNR (food supplement) in the management on sleep quality and mood alteration in cancer patients
- Conditions
- Breast Cancer, Lung Cancer, Colon Cancer
- Trial name
- NCT02883790
- Testing
- Somnage
- Where
- 5 sites in Italy
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Helsinn Healthcare SA
Cancer of the Colon
Behavioral Economic Incentives and Cancer Health Risk Assessment
This is an RCT among UPHS employees between ages 50-64 comparing no incentive and a loss-framed incentive for completing cancer health risk assessment.
- Trial name
- NCT03068052
- Testing
- No incentive, Incentive
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cancer of the Colon
Colorectal Cancer Screening in a Community Health Setting
This randomized controlled pilot study at the Health Annex, Family Practice \& Counseling Network (FPCN), a community clinic in Southwest Philadelphia, aimed at providing data on the feasibility of a mailed FIT approach to CRC…
- Trial name
- NCT03072095
- Testing
- Text-only, Text + Lottery
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cancer of Colon
Choice Architecture and Colorectal Cancer Screening Outreach
This pilot study is a 3-arm randomized control trial assessing the effectiveness of sequential or active choice in CRC (colorectal cancer) screening outreach vs.
- Trial name
- NCT03246438
- Testing
- Colonoscopy only, Colonoscopy outreach + mailed FIT follow-up, Colonoscopy + Mailed FIT outreach and follow-up
- Where
- United States
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Huntington Disease, Hereditary Breast and Ovarian Cancer
Genetic Risk: Whether, When, and How to Tell Adolescents
This study is being conducted to learn more about family communication of genetic risk information. Semi-structured interviews lasting up to one hour will be conducted with three populations: parent/child pairs at risk for…
- Conditions
- Huntington Disease, Hereditary Breast and Ovarian Cancer, Hereditary Cancer, Hereditary Non-polyposis Colon Cancer
- Trial name
- NCT03421327
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Colon Cancer, Endometrial Cancer
Healthcare Decisions Post-Testing, Risk-reducing and Preventative Strategies Using LYNCH Genetic Testing Reducing, and Preventative Strategies Using LYNCH Genetic Testing
Increase surveillance for LYNCH Syndrome
- Trial name
- NCT03322176
- Testing
- Genetic testing
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Data Collection Analysis Business Management
Colon Cancer
The Efficiency of Colon Capsule Endoscopy in Colon Cancer Screening
Main objective is to improve colorectal cancer (CRC) screening programme in the Czech Republic and decrease the disease incidence and mortality.
- Trial name
- NCT03052335
- Testing
- Pillcam® COLON 2 Capsule, Colonoscopy
- Where
- Czechia
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Military University Hospital, Prague
Colon Cancer
Robotic-assisted Left Hemicolectomy for Left Colon Cancer
The main goal of this study is to clarify if Robotic-assisted surgery could become the standard approach in patients undergoing left colonic resection.
- Trial name
- RALH (NCT03696472)
- Testing
- robotic assisted surgery, laparoscopic
- Where
- China
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Southwest Hospital, China
Colon Cancer, Colon Sessile Serrated Adenoma/Polyp
Narrow Band Imaging Versus White Light for Colonoscopy Serrate Lesions Detection
Colorectal cancer (CRC) is a leading cause of cancer death and its' incidence is rising in most European countries. Colonoscopy has been shown to reduce CRC incidence, however its effectiveness depends on the sensitivity to…
- Trial name
- NCT02876133
- Testing
- narrow band imaging withdrawal, white light withdrawal
- Where
- 3 sites in Portugal
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- Hospital Beatriz Ângelo
Colon Cancer, Colitis
Novel Listeria Vectors Secreting Gut Flora-Altering Agents to Prevent Colon Cancer and Treat Colitis
This is a simple tissue collection study with no therapeutic intent. Colon tissues will be taken from standard of care procedures.
- Trial name
- NCT03014284
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio